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The map label for this gene is malE [C]

Identifier: 158336096

GI number: 158336096

Start: 2986717

End: 2988153

Strand: Direct

Name: malE [C]

Synonym: AM1_2958

Alternate gene names: 158336096

Gene position: 2986717-2988153 (Clockwise)

Preceding gene: 158336093

Following gene: 158336098

Centisome position: 45.92

GC content: 52.19

Gene sequence:

>1437_bases
TTGGTATCGGATTTACCCTTCTTTACCTTAATCGTTGGCAGACAGCTTGCCTACCATCGGATTTTGATTTTTACTCACGG
GGGATCTAGAGTGATGAGAACGCCTGCTGAGGGACTCATCAACATGAACATGCGATCACCGCAACTCTGGCGCACCCTAA
ATCCGTTCCATCGCCTTTCCAAGCGACTGCGCTTTATGGTGCTGAGTTTGCTGGTTTGCTTGAGCGTCATCGGGGGCTAT
TGGGTGTGGGCTCAACAGCCCGTTCGCCTATCCATGATGCTCCAGGGTCAGGAAATTCCTAACTGGCAGCTGATTGTTGA
TGATTTTGAAGCCCAAAACCCCGATATCAAGATTGACCTGATTGAAGGCCCCAACGCCACCAATCTTCGAGAAGATCTCT
ATACCACGTCTTTTCTGCTGGGCGATTCCCCCTACGACTTGATCTATATGGATATCGTCTGGGCCCCCAAATTCGCTGCT
GCGGGATGGCTGTTAGACCTGTCTGATCGCATTTCTGATGAAGAACTCGCTGAATTTATGACCGGCGACGTGGATGGGGG
ACGCTATGAAGGGGGGCTGTATCGGATGCCCTTCCGCTCCGATGGCGGCATGCTCTACTATCGGCAGGATTTGCTATCTG
AGGCTGGCTTTGAACCACCTGAAACCACGGCTGAACTGATCGACATTTCCAAAGCTCTGCAATCTCAAAACAAAGCCCAG
TGGGGGTATGTCTGGCAGGGCAAGCAGTACGAAGGGGCGGCAGCCATGTTTGTGGAAATGCTGGAAGGCTTTGGTGGCTA
CTGGGTCAATCCTGAAACCAAAGAGGTGGGACTCGATAGTCCAGAAGCTATTGAGTCCCTGAAATTTCTGCAAACCACTG
TTGCCGATAAAATTTCTCCTCCAGGAACAACTGCCACGGATGAAGAAGTGGCTCGCCTCCAGTTCCAAAGTGGCAACACA
GTGTTTATGCGCAACTGGCCCTATGCTTGGAAACTCGGCAACACCGAACCAAGCTCCAAAATCCAAGGCAAGTTTGGGAT
TAAGCCCATGGTCCATACCGCAGGGCTGGGGAGCGGTGCCTGCCAAGGGGGCTGGGGTGTCGGCATCTCGAAAACCACGC
GTCATGCCGATGAAGCCTGGCGGGCCGTCGAATACTTTAGCAGCACAGAAGCCCAGCGTAAGTTTATTTTGGCCTCTGGG
TTTGTGCCCAGCCGAAAAGCGCTATTTACCGACCCCACCCTGGTCAAGGAATATGAGTATTTACCTGACTTACAGAAGGT
GATTGAGAGCTCTGTATTGCGTCCGCCCATTGCCCAATATGCTCAGGCCTCCGATATTTTACAGCGCTATCTCAGCGCAG
CCTTAACAGGACGGCAAACCCCTGAGAAAGCCATGCAAGCTGCGGCCCAGGAAACCCGACAGCTATTAAAAACCTAA

Upstream 100 bases:

>100_bases
CTGGTCAATCCAGTCCGAGCGCGTCGGTTGCTGCAAAAACTTGATCGTGGGTTGCGCCCGCTCAGGAGCATCAGTGGGCA
ACGTTGAGTGAGTCATCGTA

Downstream 100 bases:

>100_bases
TTACCCCAACTTTTACAGGGTCAAGGCAACCCGAAATCCAATATCATTGACGCGGTTGTTGGGAGTATAGCGACTGCGAT
TGGCGGCGCGACAATACCGG

Product: sugar ABC transporter solute-binding protein

Products: ADP; phosphate; maltose [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 478; Mature: 478

Protein sequence:

>478_residues
MVSDLPFFTLIVGRQLAYHRILIFTHGGSRVMRTPAEGLINMNMRSPQLWRTLNPFHRLSKRLRFMVLSLLVCLSVIGGY
WVWAQQPVRLSMMLQGQEIPNWQLIVDDFEAQNPDIKIDLIEGPNATNLREDLYTTSFLLGDSPYDLIYMDIVWAPKFAA
AGWLLDLSDRISDEELAEFMTGDVDGGRYEGGLYRMPFRSDGGMLYYRQDLLSEAGFEPPETTAELIDISKALQSQNKAQ
WGYVWQGKQYEGAAAMFVEMLEGFGGYWVNPETKEVGLDSPEAIESLKFLQTTVADKISPPGTTATDEEVARLQFQSGNT
VFMRNWPYAWKLGNTEPSSKIQGKFGIKPMVHTAGLGSGACQGGWGVGISKTTRHADEAWRAVEYFSSTEAQRKFILASG
FVPSRKALFTDPTLVKEYEYLPDLQKVIESSVLRPPIAQYAQASDILQRYLSAALTGRQTPEKAMQAAAQETRQLLKT

Sequences:

>Translated_478_residues
MVSDLPFFTLIVGRQLAYHRILIFTHGGSRVMRTPAEGLINMNMRSPQLWRTLNPFHRLSKRLRFMVLSLLVCLSVIGGY
WVWAQQPVRLSMMLQGQEIPNWQLIVDDFEAQNPDIKIDLIEGPNATNLREDLYTTSFLLGDSPYDLIYMDIVWAPKFAA
AGWLLDLSDRISDEELAEFMTGDVDGGRYEGGLYRMPFRSDGGMLYYRQDLLSEAGFEPPETTAELIDISKALQSQNKAQ
WGYVWQGKQYEGAAAMFVEMLEGFGGYWVNPETKEVGLDSPEAIESLKFLQTTVADKISPPGTTATDEEVARLQFQSGNT
VFMRNWPYAWKLGNTEPSSKIQGKFGIKPMVHTAGLGSGACQGGWGVGISKTTRHADEAWRAVEYFSSTEAQRKFILASG
FVPSRKALFTDPTLVKEYEYLPDLQKVIESSVLRPPIAQYAQASDILQRYLSAALTGRQTPEKAMQAAAQETRQLLKT
>Mature_478_residues
MVSDLPFFTLIVGRQLAYHRILIFTHGGSRVMRTPAEGLINMNMRSPQLWRTLNPFHRLSKRLRFMVLSLLVCLSVIGGY
WVWAQQPVRLSMMLQGQEIPNWQLIVDDFEAQNPDIKIDLIEGPNATNLREDLYTTSFLLGDSPYDLIYMDIVWAPKFAA
AGWLLDLSDRISDEELAEFMTGDVDGGRYEGGLYRMPFRSDGGMLYYRQDLLSEAGFEPPETTAELIDISKALQSQNKAQ
WGYVWQGKQYEGAAAMFVEMLEGFGGYWVNPETKEVGLDSPEAIESLKFLQTTVADKISPPGTTATDEEVARLQFQSGNT
VFMRNWPYAWKLGNTEPSSKIQGKFGIKPMVHTAGLGSGACQGGWGVGISKTTRHADEAWRAVEYFSSTEAQRKFILASG
FVPSRKALFTDPTLVKEYEYLPDLQKVIESSVLRPPIAQYAQASDILQRYLSAALTGRQTPEKAMQAAAQETRQLLKT

Specific function: Probably part of a binding-protein-dependent transport system [H]

COG id: COG1653

COG function: function code G; ABC-type sugar transport system, periplasmic component

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial solute-binding protein 1 family [H]

Homologues:

None

Paralogues:

None

Copy number: 660 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 720 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 240 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase,

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006059 [H]

Pfam domain/function: PF01547 SBP_bac_1 [H]

EC number: NA

Molecular weight: Translated: 53709; Mature: 53709

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSDLPFFTLIVGRQLAYHRILIFTHGGSRVMRTPAEGLINMNMRSPQLWRTLNPFHRLS
CCCCCHHHHHHHHHHHEEEEEEEEEECCCCEEECCHHHEEECCCCCCHHHHHCCHHHHHH
KRLRFMVLSLLVCLSVIGGYWVWAQQPVRLSMMLQGQEIPNWQLIVDDFEAQNPDIKIDL
HHHHHHHHHHHHHHHHHCCEEEECCCCEEEEEEEECCCCCCCEEEEECCCCCCCCEEEEE
IEGPNATNLREDLYTTSFLLGDSPYDLIYMDIVWAPKFAAAGWLLDLSDRISDEELAEFM
ECCCCCCCHHHHHHHHHEEECCCCCCEEEEEEEECCCHHHCCEEEECHHCCCHHHHHHHH
TGDVDGGRYEGGLYRMPFRSDGGMLYYRQDLLSEAGFEPPETTAELIDISKALQSQNKAQ
HCCCCCCEECCCEEECCEECCCCEEEEHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCC
WGYVWQGKQYEGAAAMFVEMLEGFGGYWVNPETKEVGLDSPEAIESLKFLQTTVADKISP
CCEEECCCCCCCHHHHHHHHHHCCCCEECCCCCHHCCCCCHHHHHHHHHHHHHHHHCCCC
PGTTATDEEVARLQFQSGNTVFMRNWPYAWKLGNTEPSSKIQGKFGIKPMVHTAGLGSGA
CCCCCCHHHHHHEEECCCCEEEEECCCEEEECCCCCCCCCCCCCCCCCCHHHCCCCCCCC
CQGGWGVGISKTTRHADEAWRAVEYFSSTEAQRKFILASGFVPSRKALFTDPTLVKEYEY
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHEEEEECCCCCCCCCEECCCHHHHHHHH
LPDLQKVIESSVLRPPIAQYAQASDILQRYLSAALTGRQTPEKAMQAAAQETRQLLKT
CHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVSDLPFFTLIVGRQLAYHRILIFTHGGSRVMRTPAEGLINMNMRSPQLWRTLNPFHRLS
CCCCCHHHHHHHHHHHEEEEEEEEEECCCCEEECCHHHEEECCCCCCHHHHHCCHHHHHH
KRLRFMVLSLLVCLSVIGGYWVWAQQPVRLSMMLQGQEIPNWQLIVDDFEAQNPDIKIDL
HHHHHHHHHHHHHHHHHCCEEEECCCCEEEEEEEECCCCCCCEEEEECCCCCCCCEEEEE
IEGPNATNLREDLYTTSFLLGDSPYDLIYMDIVWAPKFAAAGWLLDLSDRISDEELAEFM
ECCCCCCCHHHHHHHHHEEECCCCCCEEEEEEEECCCHHHCCEEEECHHCCCHHHHHHHH
TGDVDGGRYEGGLYRMPFRSDGGMLYYRQDLLSEAGFEPPETTAELIDISKALQSQNKAQ
HCCCCCCEECCCEEECCEECCCCEEEEHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCC
WGYVWQGKQYEGAAAMFVEMLEGFGGYWVNPETKEVGLDSPEAIESLKFLQTTVADKISP
CCEEECCCCCCCHHHHHHHHHHCCCCEECCCCCHHCCCCCHHHHHHHHHHHHHHHHCCCC
PGTTATDEEVARLQFQSGNTVFMRNWPYAWKLGNTEPSSKIQGKFGIKPMVHTAGLGSGA
CCCCCCHHHHHHEEECCCCEEEEECCCEEEECCCCCCCCCCCCCCCCCCHHHCCCCCCCC
CQGGWGVGISKTTRHADEAWRAVEYFSSTEAQRKFILASGFVPSRKALFTDPTLVKEYEY
CCCCCCCCCCHHHHHHHHHHHHHHHHHCCHHHHEEEEECCCCCCCCCEECCCHHHHHHHH
LPDLQKVIESSVLRPPIAQYAQASDILQRYLSAALTGRQTPEKAMQAAAQETRQLLKT
CHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; maltose [Periplasm]; H2O [C]

Specific reaction: ATP + maltose [Periplasm] + H2O = ADP + phosphate + maltose [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10567266 [H]