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The map label for this gene is nlpI [C]

Identifier: 158336093

GI number: 158336093

Start: 2984387

End: 2985541

Strand: Direct

Name: nlpI [C]

Synonym: AM1_2955

Alternate gene names: 158336093

Gene position: 2984387-2985541 (Clockwise)

Preceding gene: 158336092

Following gene: 158336096

Centisome position: 45.89

GC content: 42.08

Gene sequence:

>1155_bases
ATGACTCAGTCACTGACGGATTGGGACGAGGATGTAGCGGTCGATCCGGAAGCAGGGTATCAAGCTTTACTGAGGACTAT
ACGTTGGACAAACGGATTTGGCCTATCGTTTGTACGCTGTTCGCCTGCAGAGGCAGAACAATTAATTGAACGAGTTCAGC
TAGATTTAGGGAGTCAACCACCTTCGTCTGAATCGCAAAAAAAGATTGAGGTTTTAAGGTTAGACCAGCCTATCGATAAC
TTTTATGAAATGGTTGCAGCCTTACCAAATCAGGATCAAATAGACGTTTTATTTATTAAAGGCATTGAAAAGTCTTTGAT
TGCTGATATTAAACCTGGATATCAAGGAGAGGGAGAATATTACAACCTCAACACACTGCCACGCATTTTAGGCCACTTGA
ATTTACAGCGGGAGCGGTTTCGAGATGATTTTGATATTTGCTTTATCTTTTTGGTGCCTCTATTTGCGCTGAAATACTTT
ACTAGAAGGGCACCTGACTTTTTCGATTGGCGATCGGGGGTTTGGGCGTTTGGCACTAATTCACAAGTTCTTCAGCAAGA
ATCATTACGTATTCTTCAGGAAGGAAATTTTGCAAAGTATTTAGCTCTCTCACCACAAGAGCGAACTCAGAAAATTTTAG
AAATTCAAGAACTAATTGATGACATTTATGCTGTTCCACGAGAACAAATCTACTTGTTCTTTGAGCTAGGAAATCTTTTT
GCGGCTGAAGCAGATTATCGATCTGCGATCGCAAGCTATGACAAAGCCCTCGAATTTAAGCCGGATGATGATCAAGCCTG
GTACAACCGAGGCATTGCTCTACGTCAATTAGGGCGTCTCGAAGAGGCGATCGCGAGCTATGACAAAGCCCTCGAATTTA
AGCCGGATGATGATCAAGCCTGGTACAACCGAGGCATTGCTCTACATCAATTAGGGCGTTTCGAAGAGGCGATCACAAGC
TATGATAAAGCCCTCGCATTTAAGCCGGATGATGCTATGACCTTGCTCAACCGGGGAAACGCTTTCCTGCAACTAAGGAA
ATATAAAGATGGTTTTCAGAGTTTTGAAAAAGCTCTTGGGCCAAAGCCTAATATTGCAATTAAGCTAATATTTCAGGTTA
TAAAGTTTGTAGGTAGAATACGCTTTAAGTTTTGA

Upstream 100 bases:

>100_bases
TAATCCGAGGGATCCAAGAATTTCAGATTGCTTTAAATAAGGCTGAGGATGCGGCAATGACAAAGGTCGAGGCAAAGACT
AAAACTGAGGATGAAGCATC

Downstream 100 bases:

>100_bases
TATATTTCATCTCAATCCGCCTTTAGTAGCTACTAAATTCAGGTAATTCGTCTAAGGAGTTAGATATCCAATACCTTCGA
GTAAATCAAATCGCAGCGTT

Product: TPR domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 384; Mature: 383

Protein sequence:

>384_residues
MTQSLTDWDEDVAVDPEAGYQALLRTIRWTNGFGLSFVRCSPAEAEQLIERVQLDLGSQPPSSESQKKIEVLRLDQPIDN
FYEMVAALPNQDQIDVLFIKGIEKSLIADIKPGYQGEGEYYNLNTLPRILGHLNLQRERFRDDFDICFIFLVPLFALKYF
TRRAPDFFDWRSGVWAFGTNSQVLQQESLRILQEGNFAKYLALSPQERTQKILEIQELIDDIYAVPREQIYLFFELGNLF
AAEADYRSAIASYDKALEFKPDDDQAWYNRGIALRQLGRLEEAIASYDKALEFKPDDDQAWYNRGIALHQLGRFEEAITS
YDKALAFKPDDAMTLLNRGNAFLQLRKYKDGFQSFEKALGPKPNIAIKLIFQVIKFVGRIRFKF

Sequences:

>Translated_384_residues
MTQSLTDWDEDVAVDPEAGYQALLRTIRWTNGFGLSFVRCSPAEAEQLIERVQLDLGSQPPSSESQKKIEVLRLDQPIDN
FYEMVAALPNQDQIDVLFIKGIEKSLIADIKPGYQGEGEYYNLNTLPRILGHLNLQRERFRDDFDICFIFLVPLFALKYF
TRRAPDFFDWRSGVWAFGTNSQVLQQESLRILQEGNFAKYLALSPQERTQKILEIQELIDDIYAVPREQIYLFFELGNLF
AAEADYRSAIASYDKALEFKPDDDQAWYNRGIALRQLGRLEEAIASYDKALEFKPDDDQAWYNRGIALHQLGRFEEAITS
YDKALAFKPDDAMTLLNRGNAFLQLRKYKDGFQSFEKALGPKPNIAIKLIFQVIKFVGRIRFKF
>Mature_383_residues
TQSLTDWDEDVAVDPEAGYQALLRTIRWTNGFGLSFVRCSPAEAEQLIERVQLDLGSQPPSSESQKKIEVLRLDQPIDNF
YEMVAALPNQDQIDVLFIKGIEKSLIADIKPGYQGEGEYYNLNTLPRILGHLNLQRERFRDDFDICFIFLVPLFALKYFT
RRAPDFFDWRSGVWAFGTNSQVLQQESLRILQEGNFAKYLALSPQERTQKILEIQELIDDIYAVPREQIYLFFELGNLFA
AEADYRSAIASYDKALEFKPDDDQAWYNRGIALRQLGRLEEAIASYDKALEFKPDDDQAWYNRGIALHQLGRFEEAITSY
DKALAFKPDDAMTLLNRGNAFLQLRKYKDGFQSFEKALGPKPNIAIKLIFQVIKFVGRIRFKF

Specific function: May Be Involved In Cell Division. Overexpression Of Nlpi Results In The Loss Of The Rod Morphology And The Formation Of Single Prolate Ellipsoids And Pairs Of Prolate Ellipsoids Joined By Partial Constrictions. [C]

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Attached To The Membrane By A Lipid Anchor [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 4 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI32307148, Length=135, Percent_Identity=31.8518518518519, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI32307150, Length=135, Percent_Identity=31.8518518518519, Blast_Score=74, Evalue=3e-13,
Organism=Homo sapiens, GI301336134, Length=230, Percent_Identity=25.2173913043478, Blast_Score=67, Evalue=3e-11,
Organism=Homo sapiens, GI83415184, Length=218, Percent_Identity=26.1467889908257, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI17647755, Length=135, Percent_Identity=32.5925925925926, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24585827, Length=135, Percent_Identity=32.5925925925926, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24585829, Length=135, Percent_Identity=32.5925925925926, Blast_Score=73, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24647123, Length=178, Percent_Identity=25.8426966292135, Blast_Score=72, Evalue=9e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001440
- InterPro:   IPR013026
- InterPro:   IPR011990
- InterPro:   IPR019734 [H]

Pfam domain/function: PF00515 TPR_1 [H]

EC number: NA

Molecular weight: Translated: 44399; Mature: 44268

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS50005 TPR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.5 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQSLTDWDEDVAVDPEAGYQALLRTIRWTNGFGLSFVRCSPAEAEQLIERVQLDLGSQP
CCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHCCCCC
PSSESQKKIEVLRLDQPIDNFYEMVAALPNQDQIDVLFIKGIEKSLIADIKPGYQGEGEY
CCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHCCCCCCCCCCE
YNLNTLPRILGHLNLQRERFRDDFDICFIFLVPLFALKYFTRRAPDFFDWRSGVWAFGTN
ECCHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCEEEECCC
SQVLQQESLRILQEGNFAKYLALSPQERTQKILEIQELIDDIYAVPREQIYLFFELGNLF
HHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHEEEEEEECCHH
AAEADYRSAIASYDKALEFKPDDDQAWYNRGIALRQLGRLEEAIASYDKALEFKPDDDQA
HCCHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
WYNRGIALHQLGRFEEAITSYDKALAFKPDDAMTLLNRGNAFLQLRKYKDGFQSFEKALG
HHHCCHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHCCCHHEEHHHHHHHHHHHHHHCC
PKPNIAIKLIFQVIKFVGRIRFKF
CCCCHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TQSLTDWDEDVAVDPEAGYQALLRTIRWTNGFGLSFVRCSPAEAEQLIERVQLDLGSQP
CCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHCCCCC
PSSESQKKIEVLRLDQPIDNFYEMVAALPNQDQIDVLFIKGIEKSLIADIKPGYQGEGEY
CCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCEEEEEECCCHHHHHHHCCCCCCCCCCE
YNLNTLPRILGHLNLQRERFRDDFDICFIFLVPLFALKYFTRRAPDFFDWRSGVWAFGTN
ECCHHHHHHHHHCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCEEEECCC
SQVLQQESLRILQEGNFAKYLALSPQERTQKILEIQELIDDIYAVPREQIYLFFELGNLF
HHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHCCHHHEEEEEEECCHH
AAEADYRSAIASYDKALEFKPDDDQAWYNRGIALRQLGRLEEAIASYDKALEFKPDDDQA
HCCHHHHHHHHHHHHHCCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
WYNRGIALHQLGRFEEAITSYDKALAFKPDDAMTLLNRGNAFLQLRKYKDGFQSFEKALG
HHHCCHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHCCCHHEEHHHHHHHHHHHHHHCC
PKPNIAIKLIFQVIKFVGRIRFKF
CCCCHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1368342; 8905231 [H]