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The map label for this gene is petH [H]

Identifier: 158336080

GI number: 158336080

Start: 2973157

End: 2974047

Strand: Reverse

Name: petH [H]

Synonym: AM1_2941

Alternate gene names: 158336080

Gene position: 2974047-2973157 (Counterclockwise)

Preceding gene: 158336081

Following gene: 158336076

Centisome position: 45.73

GC content: 48.37

Gene sequence:

>891_bases
ATGCAGCTAAAAGAAAAAATCCCAGTCAATATTTATCGTCCCAAAGAACCTTTAACGAGTCAGTGTCTGACTAATGAAGA
GCTGGTTCAGCCCGGTGGAGAAGGAACAGTTCGCCACATCACCTTTGATTTAGCAGGGAGCGATTTTCATTATCTTGAAG
GGCAAAGCTTAGGGATTATTCCAGAAGGGACCGATGAAAACGGTCGCCTTCATAAGCTGCGGCTTTATTCAATTGCCTCC
ACGCGCCATGGTGATCAGGGCGACGACAAAACCGTCTCCTTATGCGTTCGGCAGTTGGAATATAATCATCCCGAGACAGG
CGAGCGGGTATATGGCGTTTGCTCTAGCTATTTAAACCAGCTCCAACCCGGTGCTCCTGTTAAAATCACAGGTCCGGTGG
GCAAAGAAATGCTCTTGCCTGATGATCCAGAAGCCAATGTGATTATGATTGCCACAGGTACAGGCATCGCCCCGTTTCGG
GCTTATCTGTGGCGATTGTTTCAGGAAAAGCATCCTGACTATCAGTTCAAAGGCAATGCATGGCTGTTCTTTGGTGTGCC
CTACACGGCCAATATCCTCTATAAAGAGCAACTAGAAGCCTTAGCCACGCAATTCTCAGATCAGTTCCAACTCACCTATG
CCATTAGTCGGGAGCAGCAAAATCCCCAGGGCGGCAAGATGTATATTCAACATCGTATCGCCGAGCAGGCAGATGCCCTT
TGGGAATTGATACAGAATGACAAGACCCATACCTATATCTGTGGTTTGAAAGGTATGGAAGGGGGCATTGATGACGGCAT
GTCCGTCGCCGCCCAAAAGCATGGCGTCGATTGGATCGAATATCGCAAAGCCCTCAAGAAAGCCGGACGATGGCACGTTG
AGACTTATTAA

Upstream 100 bases:

>100_bases
GACAATGGGATCCAACGAATACCCCTAGGCTTGTTGGAGTCTTAATATCTCCTCCACTGCCAGTTATGGTGGTGGTTCGC
TCACTTCAGATTCAATCTCT

Downstream 100 bases:

>100_bases
AGTTAGGTCAATTAATCATTTCTTTGGCATTCGCGATATCTTCACTTTTGACTGATATCTTTAATTCCAGAGATAAGCAA
ACCCTTTAAACCTCATTAGC

Product: ferredoxin-NADP reductase PetH

Products: NA

Alternate protein names: FNR [H]

Number of amino acids: Translated: 296; Mature: 296

Protein sequence:

>296_residues
MQLKEKIPVNIYRPKEPLTSQCLTNEELVQPGGEGTVRHITFDLAGSDFHYLEGQSLGIIPEGTDENGRLHKLRLYSIAS
TRHGDQGDDKTVSLCVRQLEYNHPETGERVYGVCSSYLNQLQPGAPVKITGPVGKEMLLPDDPEANVIMIATGTGIAPFR
AYLWRLFQEKHPDYQFKGNAWLFFGVPYTANILYKEQLEALATQFSDQFQLTYAISREQQNPQGGKMYIQHRIAEQADAL
WELIQNDKTHTYICGLKGMEGGIDDGMSVAAQKHGVDWIEYRKALKKAGRWHVETY

Sequences:

>Translated_296_residues
MQLKEKIPVNIYRPKEPLTSQCLTNEELVQPGGEGTVRHITFDLAGSDFHYLEGQSLGIIPEGTDENGRLHKLRLYSIAS
TRHGDQGDDKTVSLCVRQLEYNHPETGERVYGVCSSYLNQLQPGAPVKITGPVGKEMLLPDDPEANVIMIATGTGIAPFR
AYLWRLFQEKHPDYQFKGNAWLFFGVPYTANILYKEQLEALATQFSDQFQLTYAISREQQNPQGGKMYIQHRIAEQADAL
WELIQNDKTHTYICGLKGMEGGIDDGMSVAAQKHGVDWIEYRKALKKAGRWHVETY
>Mature_296_residues
MQLKEKIPVNIYRPKEPLTSQCLTNEELVQPGGEGTVRHITFDLAGSDFHYLEGQSLGIIPEGTDENGRLHKLRLYSIAS
TRHGDQGDDKTVSLCVRQLEYNHPETGERVYGVCSSYLNQLQPGAPVKITGPVGKEMLLPDDPEANVIMIATGTGIAPFR
AYLWRLFQEKHPDYQFKGNAWLFFGVPYTANILYKEQLEALATQFSDQFQLTYAISREQQNPQGGKMYIQHRIAEQADAL
WELIQNDKTHTYICGLKGMEGGIDDGMSVAAQKHGVDWIEYRKALKKAGRWHVETY

Specific function: Catalyzes The 6-Electron Reduction Of Sulfite To Sulfide. This Is One Of Several Activities Required For The Biosynthesis Of L-Cysteine From Sulfate. The Flavo-Protein Component Catalyzes The Electron Flow From Nadph -> FAD -> Fmn To The Hemoprotein Compo

COG id: COG0369

COG function: function code P; Sulfite reductase, alpha subunit (flavoprotein)

Gene ontology:

Cell location: Cellular thylakoid membrane; Peripheral membrane protein; Cytoplasmic side. Note=May be bound to the thylakoid membrane or anchored to the thylakoid-bound phycobilisomes (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 FAD-binding FR-type domain [H]

Homologues:

Organism=Homo sapiens, GI7657393, Length=192, Percent_Identity=33.3333333333333, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI221316709, Length=192, Percent_Identity=33.3333333333333, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI221316705, Length=197, Percent_Identity=32.994923857868, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI40254422, Length=197, Percent_Identity=31.4720812182741, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI221316707, Length=142, Percent_Identity=37.3239436619718, Blast_Score=72, Evalue=5e-13,
Organism=Homo sapiens, GI24041029, Length=237, Percent_Identity=29.535864978903, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI169790958, Length=202, Percent_Identity=28.2178217821782, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI169790956, Length=202, Percent_Identity=29.7029702970297, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI10835173, Length=239, Percent_Identity=28.8702928870293, Blast_Score=68, Evalue=9e-12,
Organism=Escherichia coli, GI1789123, Length=183, Percent_Identity=33.3333333333333, Blast_Score=84, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI17554134, Length=242, Percent_Identity=28.5123966942149, Blast_Score=74, Evalue=7e-14,
Organism=Saccharomyces cerevisiae, GI6321143, Length=236, Percent_Identity=30.5084745762712, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6321832, Length=168, Percent_Identity=29.1666666666667, Blast_Score=72, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24582192, Length=235, Percent_Identity=29.3617021276596, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI17137192, Length=235, Percent_Identity=29.3617021276596, Blast_Score=89, Evalue=5e-18,
Organism=Drosophila melanogaster, GI78706872, Length=234, Percent_Identity=31.1965811965812, Blast_Score=85, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24583543, Length=234, Percent_Identity=31.1965811965812, Blast_Score=85, Evalue=6e-17,
Organism=Drosophila melanogaster, GI78706876, Length=234, Percent_Identity=31.1965811965812, Blast_Score=85, Evalue=6e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003097
- InterPro:   IPR017927
- InterPro:   IPR001709
- InterPro:   IPR012146
- InterPro:   IPR015701
- InterPro:   IPR008333
- InterPro:   IPR001433
- InterPro:   IPR008213
- InterPro:   IPR017938 [H]

Pfam domain/function: PF01383 CpcD; PF00667 FAD_binding_1; PF00970 FAD_binding_6; PF00175 NAD_binding_1 [H]

EC number: =1.18.1.2 [H]

Molecular weight: Translated: 33462; Mature: 33462

Theoretical pI: Translated: 6.18; Mature: 6.18

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLKEKIPVNIYRPKEPLTSQCLTNEELVQPGGEGTVRHITFDLAGSDFHYLEGQSLGII
CCCCCCCCEEEECCCCCHHHHHCCCHHHHCCCCCCEEEEEEEEECCCCEEEECCCEEECC
PEGTDENGRLHKLRLYSIASTRHGDQGDDKTVSLCVRQLEYNHPETGERVYGVCSSYLNQ
CCCCCCCCCEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
LQPGAPVKITGPVGKEMLLPDDPEANVIMIATGTGIAPFRAYLWRLFQEKHPDYQFKGNA
HCCCCCEEEECCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCEEECCCE
WLFFGVPYTANILYKEQLEALATQFSDQFQLTYAISREQQNPQGGKMYIQHRIAEQADAL
EEEEECCCEEHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
WELIQNDKTHTYICGLKGMEGGIDDGMSVAAQKHGVDWIEYRKALKKAGRWHVETY
HHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHCCCEEECCC
>Mature Secondary Structure
MQLKEKIPVNIYRPKEPLTSQCLTNEELVQPGGEGTVRHITFDLAGSDFHYLEGQSLGII
CCCCCCCCEEEECCCCCHHHHHCCCHHHHCCCCCCEEEEEEEEECCCCEEEECCCEEECC
PEGTDENGRLHKLRLYSIASTRHGDQGDDKTVSLCVRQLEYNHPETGERVYGVCSSYLNQ
CCCCCCCCCEEEEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHH
LQPGAPVKITGPVGKEMLLPDDPEANVIMIATGTGIAPFRAYLWRLFQEKHPDYQFKGNA
HCCCCCEEEECCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCEEECCCE
WLFFGVPYTANILYKEQLEALATQFSDQFQLTYAISREQQNPQGGKMYIQHRIAEQADAL
EEEEECCCEEHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
WELIQNDKTHTYICGLKGMEGGIDDGMSVAAQKHGVDWIEYRKALKKAGRWHVETY
HHHHHCCCCEEEEEECCCCCCCCCCCHHHHHHHCCCHHHHHHHHHHHCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12240834 [H]