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The map label for this gene is ygaF [H]

Identifier: 158336079

GI number: 158336079

Start: 2972414

End: 2972968

Strand: Direct

Name: ygaF [H]

Synonym: AM1_2940

Alternate gene names: 158336079

Gene position: 2972414-2972968 (Clockwise)

Preceding gene: 158336078

Following gene: 158336085

Centisome position: 45.7

GC content: 50.63

Gene sequence:

>555_bases
ATGAAACCGCTACGCCATCATCTAACCCGTATCTGTCTTGTTCTGGGACTGATTGTTTCCCTAGTTATGGCTGCCCCTGC
AGCTTTTGCCATGGGGGGTGACCCACCGCCTCTGGATCAACCTGCACCCACATTCACATTGCCTAGCAATACAGGGGATG
GTGAGGTGTCATTATCGGACTATCGAGGTCAGTGGGTGGTTTTATACTTCTACCCCCAAGACTTTACGCCGGGATGTACT
GTCGAAGCCCAACGGTTCCAGCAGGACCTACCGAAATATATCGAGCGCAACACCCAAGTCATTGGCGTTAGCGTTGACTC
CGTAGATAGCCACGCTGAATTTTGTGATTCTGAAGGGCTGAAATTTCCCTTGTTAGCCGATGAAGATGGCAGTGTGAGTA
AAGCCTATGGCTCTTGGATGAGCTACTTTTCCCTACGGCACACTTATTTGATCGATCCAGAGGGAATTCTGCGAGAACAG
TACGTCAAGGTGCGTCCTGTGATCCATAGCGAAGAAGTGTTAGCCCGCTTAGACGAACTCCAAGCCGCGAGTTGA

Upstream 100 bases:

>100_bases
CCTGGATGCAGCGAAGCGATGATTATCTCTATCGGGCCAAATCGGCAGGGCGCAATCAAGTGATGTGCAGGTAATCTCTT
TTTCCAGGTATAACCAAAAT

Downstream 100 bases:

>100_bases
ACAGAATCCTGATTTGCCAAAAAAAAACGCCCCCGAAAGGGGGCATATTTGTTGGAATGCACGTATTGGGTTGATGACGA
CCCAACGCGCTAATGAGGTT

Product: alkyl hydroperoxide reductase/ Thiol specific antioxidant

Products: NA

Alternate protein names: Bacterioferritin comigratory protein; Thioredoxin reductase [H]

Number of amino acids: Translated: 184; Mature: 184

Protein sequence:

>184_residues
MKPLRHHLTRICLVLGLIVSLVMAAPAAFAMGGDPPPLDQPAPTFTLPSNTGDGEVSLSDYRGQWVVLYFYPQDFTPGCT
VEAQRFQQDLPKYIERNTQVIGVSVDSVDSHAEFCDSEGLKFPLLADEDGSVSKAYGSWMSYFSLRHTYLIDPEGILREQ
YVKVRPVIHSEEVLARLDELQAAS

Sequences:

>Translated_184_residues
MKPLRHHLTRICLVLGLIVSLVMAAPAAFAMGGDPPPLDQPAPTFTLPSNTGDGEVSLSDYRGQWVVLYFYPQDFTPGCT
VEAQRFQQDLPKYIERNTQVIGVSVDSVDSHAEFCDSEGLKFPLLADEDGSVSKAYGSWMSYFSLRHTYLIDPEGILREQ
YVKVRPVIHSEEVLARLDELQAAS
>Mature_184_residues
MKPLRHHLTRICLVLGLIVSLVMAAPAAFAMGGDPPPLDQPAPTFTLPSNTGDGEVSLSDYRGQWVVLYFYPQDFTPGCT
VEAQRFQQDLPKYIERNTQVIGVSVDSVDSHAEFCDSEGLKFPLLADEDGSVSKAYGSWMSYFSLRHTYLIDPEGILREQ
YVKVRPVIHSEEVLARLDELQAAS

Specific function: Unknown

COG id: COG1225

COG function: function code O; Peroxiredoxin

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI4505591, Length=152, Percent_Identity=34.8684210526316, Blast_Score=81, Evalue=6e-16,
Organism=Homo sapiens, GI32455266, Length=152, Percent_Identity=34.8684210526316, Blast_Score=81, Evalue=6e-16,
Organism=Homo sapiens, GI32455264, Length=152, Percent_Identity=34.8684210526316, Blast_Score=81, Evalue=6e-16,
Organism=Homo sapiens, GI5453549, Length=132, Percent_Identity=36.3636363636364, Blast_Score=78, Evalue=4e-15,
Organism=Homo sapiens, GI5802974, Length=153, Percent_Identity=33.3333333333333, Blast_Score=77, Evalue=7e-15,
Organism=Homo sapiens, GI32189392, Length=152, Percent_Identity=36.8421052631579, Blast_Score=77, Evalue=7e-15,
Organism=Homo sapiens, GI32483377, Length=132, Percent_Identity=33.3333333333333, Blast_Score=74, Evalue=6e-14,
Organism=Escherichia coli, GI1788825, Length=146, Percent_Identity=34.2465753424658, Blast_Score=91, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI32565831, Length=152, Percent_Identity=34.8684210526316, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193204376, Length=152, Percent_Identity=34.8684210526316, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6319407, Length=163, Percent_Identity=30.0613496932515, Blast_Score=70, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323613, Length=154, Percent_Identity=34.4155844155844, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6320661, Length=113, Percent_Identity=35.3982300884956, Blast_Score=63, Evalue=2e-11,
Organism=Drosophila melanogaster, GI17738015, Length=151, Percent_Identity=39.0728476821192, Blast_Score=97, Evalue=5e-21,
Organism=Drosophila melanogaster, GI24656348, Length=151, Percent_Identity=37.7483443708609, Blast_Score=81, Evalue=4e-16,
Organism=Drosophila melanogaster, GI17864676, Length=151, Percent_Identity=37.7483443708609, Blast_Score=81, Evalue=4e-16,
Organism=Drosophila melanogaster, GI17157991, Length=153, Percent_Identity=33.9869281045752, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24641739, Length=153, Percent_Identity=33.9869281045752, Blast_Score=76, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21357347, Length=151, Percent_Identity=31.1258278145695, Blast_Score=69, Evalue=1e-12,

Paralogues:

None

Copy number: 920 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000866
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00578 AhpC-TSA [H]

EC number: =1.11.1.15 [H]

Molecular weight: Translated: 20462; Mature: 20462

Theoretical pI: Translated: 4.58; Mature: 4.58

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPLRHHLTRICLVLGLIVSLVMAAPAAFAMGGDPPPLDQPAPTFTLPSNTGDGEVSLSD
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCEECCCCCCCCEEEEEC
YRGQWVVLYFYPQDFTPGCTVEAQRFQQDLPKYIERNTQVIGVSVDSVDSHAEFCDSEGL
CCCCEEEEEEECCCCCCCCCEEHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHCCCCC
KFPLLADEDGSVSKAYGSWMSYFSLRHTYLIDPEGILREQYVKVRPVIHSEEVLARLDEL
EEEEEECCCCCHHHHHHHHHHHHHHHCEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHH
QAAS
HCCC
>Mature Secondary Structure
MKPLRHHLTRICLVLGLIVSLVMAAPAAFAMGGDPPPLDQPAPTFTLPSNTGDGEVSLSD
CCHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCEECCCCCCCCEEEEEC
YRGQWVVLYFYPQDFTPGCTVEAQRFQQDLPKYIERNTQVIGVSVDSVDSHAEFCDSEGL
CCCCEEEEEEECCCCCCCCCEEHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHCCCCC
KFPLLADEDGSVSKAYGSWMSYFSLRHTYLIDPEGILREQYVKVRPVIHSEEVLARLDEL
EEEEEECCCCCHHHHHHHHHHHHHHHCEEEECCHHHHHHHHHHHCCCCCHHHHHHHHHHH
QAAS
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]