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The map label for this gene is tldD [C]

Identifier: 158335616

GI number: 158335616

Start: 2487563

End: 2489032

Strand: Reverse

Name: tldD [C]

Synonym: AM1_2466

Alternate gene names: 158335616

Gene position: 2489032-2487563 (Counterclockwise)

Preceding gene: 158335619

Following gene: 158335615

Centisome position: 38.27

GC content: 50.68

Gene sequence:

>1470_bases
ATGTCTCCAACAGCGCTGCTTTCCAAAGAACTGCCGACCCTAGAGTATTCTGCAACGCGCGATCGCTTTGACGATACCTG
GCGTTCGCCCTTGTCGACTCTATTGGGGTTAGGCCGAGCAGCTGGAGCCGATTTTGTCGAATTTTTCCTAGAGCGGGTTA
ACTATATCAGTTGCCTCGCCGAAGAAGATGCCATCACCAGCATCTCACCCCGATTGGTTGCGGGCGCGGGTGTACGCGTA
TTTCTGGGCAAGGGAGATTGCTACGTCAGTACCAATGATATGAGCTTTAAGGGCCTGAAGTCGGCCTTAGAAAAAGCGCT
CTCAATTCTGGGATTGAACCTACCGGGGCCTCAAGCCTTTATTCCTGAAATCAACCTAGAGCTGTTGCGAGATTACGCCT
CTGTCAATGGCAAAGAGACTTGGCTAGCCAAGTGTAGCTCTATGCAGGAAATGGGCGATATTTTGCTAACTGCTAATGCC
CAATTGAACAAAGATGCTGCTCATGTACAGTCTCGTCGCGCCACCTATTTCCGTGATTGGCAAGAAGTTTTAGTGGCGGC
TAGTGATGGGGTATTTGCCCGTGATATCCGCTTGACTCAATCCGTTGGCTATAGCTTGCTCTGTGCAGAAGGCAGCGATC
GCGCTTCCATTAACAAGCGGGTTGGTGCCACCAATAACCCTAATTTTCTGCGCTCCTGGCAGTATGCCGAAGATTCAGCA
GAAGTCTCAGAATCCGCCGGGCAGATGCTTCATGCGGACTATGTGGAGTCTGGTAATTACCCGATTATTATGGCTAATGA
GTTTGGCGGAGTGATCTTCCATGAAGCCTGTGGTCATTTGCTAGAAACGACTCAGATTGAGCGCCAGACCAGTCCCTTCT
CGGAAATGAAAGGCCAAAAAATTGCCCATGAGAATCTAACGGCCTGGGACGAAGGATTATCTCCTAATGCCTTTGGTTCT
ATTGATATGGACGACGAGGGTATGCCCGTGCAGCGCACCCTCTTGATTGAAAACGGCATCCTCAAAAATTTCTTATCTGA
CCGAGCAGGCTGTATCCGCACCGGACATCCCCGCACAGGAAGTGGCCGTCGCCAAAGCTATACCCATGCGGCTGCAAGTC
GGATGCGCAATACCTATATTGCCCCCGGTAACTTCACCAATGATGGTTTGTTTAACTCGGTGGAGAAGGGTATCTATTGC
AAAAAGATGGGAGGCGGTAGCGTCGGCCCGACAGGTGAGTTCAATTTTGGTGTGGATGAAGCCTATCTGATTAAGAATGG
CAAAATCACCAAGCCCCTCAAAGGCGCGACGTTGATTGGGGAAGCCAAAGAGATTATGAAGCGGATTTCCATGTCCTCCC
AGGATTTGGGCCTAGCGGCAGGCTTCTGTGGCTCTATCAGCGGCAGTATCTACGTCACGGTGGGACAACCCCATATCAAA
GTGGATGAGATTACCGTGGGTGGTCGTTAA

Upstream 100 bases:

>100_bases
GGCATTAGCTGATTTTGTTACACTTAACTACATCAGCCCTTCCTATCAGATTTGCTGATTCCTTTTTGTTCATCTGCAAT
CAATTTGGATCACTCCATTT

Downstream 100 bases:

>100_bases
ATCGTCACTGCCTACAAGCTATTACACCTATAAATTCCAGAGAATACACCTAAAAAATAGGAGAACCCGTTAGCGTGTCT
GATGTTGCTACCATCGCTGC

Product: modulator of DNA gyrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 489; Mature: 488

Protein sequence:

>489_residues
MSPTALLSKELPTLEYSATRDRFDDTWRSPLSTLLGLGRAAGADFVEFFLERVNYISCLAEEDAITSISPRLVAGAGVRV
FLGKGDCYVSTNDMSFKGLKSALEKALSILGLNLPGPQAFIPEINLELLRDYASVNGKETWLAKCSSMQEMGDILLTANA
QLNKDAAHVQSRRATYFRDWQEVLVAASDGVFARDIRLTQSVGYSLLCAEGSDRASINKRVGATNNPNFLRSWQYAEDSA
EVSESAGQMLHADYVESGNYPIIMANEFGGVIFHEACGHLLETTQIERQTSPFSEMKGQKIAHENLTAWDEGLSPNAFGS
IDMDDEGMPVQRTLLIENGILKNFLSDRAGCIRTGHPRTGSGRRQSYTHAAASRMRNTYIAPGNFTNDGLFNSVEKGIYC
KKMGGGSVGPTGEFNFGVDEAYLIKNGKITKPLKGATLIGEAKEIMKRISMSSQDLGLAAGFCGSISGSIYVTVGQPHIK
VDEITVGGR

Sequences:

>Translated_489_residues
MSPTALLSKELPTLEYSATRDRFDDTWRSPLSTLLGLGRAAGADFVEFFLERVNYISCLAEEDAITSISPRLVAGAGVRV
FLGKGDCYVSTNDMSFKGLKSALEKALSILGLNLPGPQAFIPEINLELLRDYASVNGKETWLAKCSSMQEMGDILLTANA
QLNKDAAHVQSRRATYFRDWQEVLVAASDGVFARDIRLTQSVGYSLLCAEGSDRASINKRVGATNNPNFLRSWQYAEDSA
EVSESAGQMLHADYVESGNYPIIMANEFGGVIFHEACGHLLETTQIERQTSPFSEMKGQKIAHENLTAWDEGLSPNAFGS
IDMDDEGMPVQRTLLIENGILKNFLSDRAGCIRTGHPRTGSGRRQSYTHAAASRMRNTYIAPGNFTNDGLFNSVEKGIYC
KKMGGGSVGPTGEFNFGVDEAYLIKNGKITKPLKGATLIGEAKEIMKRISMSSQDLGLAAGFCGSISGSIYVTVGQPHIK
VDEITVGGR
>Mature_488_residues
SPTALLSKELPTLEYSATRDRFDDTWRSPLSTLLGLGRAAGADFVEFFLERVNYISCLAEEDAITSISPRLVAGAGVRVF
LGKGDCYVSTNDMSFKGLKSALEKALSILGLNLPGPQAFIPEINLELLRDYASVNGKETWLAKCSSMQEMGDILLTANAQ
LNKDAAHVQSRRATYFRDWQEVLVAASDGVFARDIRLTQSVGYSLLCAEGSDRASINKRVGATNNPNFLRSWQYAEDSAE
VSESAGQMLHADYVESGNYPIIMANEFGGVIFHEACGHLLETTQIERQTSPFSEMKGQKIAHENLTAWDEGLSPNAFGSI
DMDDEGMPVQRTLLIENGILKNFLSDRAGCIRTGHPRTGSGRRQSYTHAAASRMRNTYIAPGNFTNDGLFNSVEKGIYCK
KMGGGSVGPTGEFNFGVDEAYLIKNGKITKPLKGATLIGEAKEIMKRISMSSQDLGLAAGFCGSISGSIYVTVGQPHIKV
DEITVGGR

Specific function: Suppresses The Inhibitory Activity Of The Carbon Storage Regulator (Csra). [C]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=453, Percent_Identity=35.3200883002208, Blast_Score=224, Evalue=7e-60,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 53112; Mature: 52980

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPTALLSKELPTLEYSATRDRFDDTWRSPLSTLLGLGRAAGADFVEFFLERVNYISCLA
CCCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
EEDAITSISPRLVAGAGVRVFLGKGDCYVSTNDMSFKGLKSALEKALSILGLNLPGPQAF
CCCCCCCCCCCEEECCCEEEEEECCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
IPEINLELLRDYASVNGKETWLAKCSSMQEMGDILLTANAQLNKDAAHVQSRRATYFRDW
CCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHHH
QEVLVAASDGVFARDIRLTQSVGYSLLCAEGSDRASINKRVGATNNPNFLRSWQYAEDSA
HHHHHHCCCCCEEHHHHHHHHCCCEEEEECCCCCCHHHHCCCCCCCCCHHCCCCCCCHHH
EVSESAGQMLHADYVESGNYPIIMANEFGGVIFHEACGHLLETTQIERQTSPFSEMKGQK
HHHHHHHHHEEHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCH
IAHENLTAWDEGLSPNAFGSIDMDDEGMPVQRTLLIENGILKNFLSDRAGCIRTGHPRTG
HHHCCCCHHHCCCCCCCCCCCCCCCCCCCEEEEEEEHHHHHHHHHHCCCCCEECCCCCCC
SGRRQSYTHAAASRMRNTYIAPGNFTNDGLFNSVEKGIYCKKMGGGSVGPTGEFNFGVDE
CCCHHHHHHHHHHHHHCCEECCCCCCCCCHHHHHHCCEEEEECCCCCCCCCCCCCCCCCC
AYLIKNGKITKPLKGATLIGEAKEIMKRISMSSQDLGLAAGFCGSISGSIYVTVGQPHIK
EEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCEEEEECCCCEE
VDEITVGGR
EEEEECCCC
>Mature Secondary Structure 
SPTALLSKELPTLEYSATRDRFDDTWRSPLSTLLGLGRAAGADFVEFFLERVNYISCLA
CCHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
EEDAITSISPRLVAGAGVRVFLGKGDCYVSTNDMSFKGLKSALEKALSILGLNLPGPQAF
CCCCCCCCCCCEEECCCEEEEEECCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCC
IPEINLELLRDYASVNGKETWLAKCSSMQEMGDILLTANAQLNKDAAHVQSRRATYFRDW
CCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHCCEEEECCCCCCCHHHHHHHHHHHHHHHH
QEVLVAASDGVFARDIRLTQSVGYSLLCAEGSDRASINKRVGATNNPNFLRSWQYAEDSA
HHHHHHCCCCCEEHHHHHHHHCCCEEEEECCCCCCHHHHCCCCCCCCCHHCCCCCCCHHH
EVSESAGQMLHADYVESGNYPIIMANEFGGVIFHEACGHLLETTQIERQTSPFSEMKGQK
HHHHHHHHHEEHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHCCCH
IAHENLTAWDEGLSPNAFGSIDMDDEGMPVQRTLLIENGILKNFLSDRAGCIRTGHPRTG
HHHCCCCHHHCCCCCCCCCCCCCCCCCCCEEEEEEEHHHHHHHHHHCCCCCEECCCCCCC
SGRRQSYTHAAASRMRNTYIAPGNFTNDGLFNSVEKGIYCKKMGGGSVGPTGEFNFGVDE
CCCHHHHHHHHHHHHHCCEECCCCCCCCCHHHHHHCCEEEEECCCCCCCCCCCCCCCCCC
AYLIKNGKITKPLKGATLIGEAKEIMKRISMSSQDLGLAAGFCGSISGSIYVTVGQPHIK
EEEEECCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCEEEEECCCCEE
VDEITVGGR
EEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]