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The map label for this gene is avtA [H]

Identifier: 158335185

GI number: 158335185

Start: 2018817

End: 2020094

Strand: Reverse

Name: avtA [H]

Synonym: AM1_2028

Alternate gene names: 158335185

Gene position: 2020094-2018817 (Counterclockwise)

Preceding gene: 158335187

Following gene: 158335184

Centisome position: 31.06

GC content: 50.0

Gene sequence:

>1278_bases
ATGCCTCCAACGCTTTCGCAAATTGGCAATCAGATGTCTGCATTGACCGGTGTTCGCGCCATCATGAAGGACATTATCGA
AACCTTGAGAGCCAATCCCGATGAATCTTTTATCAATCTCAGTGCAGGCAACCCGGTTATCCTACCTGAGGTCGAACAGC
TATGGCGGGACTGCACCACCCAACTGTTAGCAAGTCCTGATTACGGTGAAGTGGTTTGCCGCTACGGCACCAGCCAGGGC
TATCAGCCCCTTGTCGATGCCATTCAAAAAGATTTTAATCAGCGCTATGGCCTAAACCTAACGGATCGCCAAATTCTGAT
TACACCAGGCAGCCAAGCCCTCTATTTCCTGGCCGCAAATGCCTTTGGCGGGGCAACTGAAACGGGGCGGCTTAAAAAGA
TTGTCTTGCCCCTCTCGCCGGACTATACCGGATATGGTGGCATTTGCCTAACCCCAGAAGCCTTAAAAGCCTATCAACCT
ACTTTAGAGATTGACGAAACGGCCCATCGGTTCAAATACAGACCAGACTTTGAACAGCTGCACTTCGATGAAACTACAGG
CTGCATTATTTTTTCGCGCCCCTGCAATCCCACGGGGAACGTCCTCAGTAAGGCCGAAGTCAAACAGATTGCCGATTTGG
CGGCTCCCTTTAATATTCCAGTCCTGATTGATTCCGCCTATGGGCCACCCTATCCCAGCCTAAATTACACCGACATCGCG
CCCATCTTAGGGAATAACATCGTCCATTGCATGAGCTTGTCTAAAGCTGGCTTGCCTGGAGAACGGGTTGGTATTGCCAT
TGGCGATGAACGTATCATTCAAATCCTAGAGGCCTTCCAAACCAATGTCTGTATTCATTCTGGGCGATACGGACAAGCGA
TCGCAGCCCAAGCCATCCAATCTGGTGCCTTGGCAGAAATATCAGTTCAGGTGATCCGACCTTACTATCAGGCCAAGCTC
GCTCTCCTTCAATCCACCCTCGACCAACATATGCCCTCCACTCTGCCCTGGTTTTTACATTTGGGTGAAGGTGCAATTTT
TGCCTGGCTATGGCTTAAGGAATTGCCCATCTCAGACTGGCAACTCTATCAACAGCTCAAACGAGTCGGGGTTATCGTTG
TCCCAGGCCACTCCTTCTTTCCCGGTTTATCCCAAGACTGGCCCCACAAACATCAATGTTTGCGCATTAGCTTAACAGCC
ACTGACGAAGAAATCACCATCGCCATGCAGCGACTTGTTCCAGTCATTGAAGAAGTGTACCGAAGCAACAACGCATAA

Upstream 100 bases:

>100_bases
GCGAGTTCAGCCCACACCCCCTAAGATATTGGGATCTGCCCTACCTGGTTGGGCAAGGTCCCAAGTGCAAAACGATAAAC
TCTTGATTGGCTCATAATCA

Downstream 100 bases:

>100_bases
TGAGGCCCCTCCAGCTCATTTCAACTTAAAGGATATGCCGGTGAGTGACTCCCTTTCCCCAGATTTACCCAATGATGACA
CTTCAGAAGAATGGTTAGAA

Product: valine--pyruvate transaminase

Products: NA

Alternate protein names: Alanine--valine transaminase; Transaminase C [H]

Number of amino acids: Translated: 425; Mature: 424

Protein sequence:

>425_residues
MPPTLSQIGNQMSALTGVRAIMKDIIETLRANPDESFINLSAGNPVILPEVEQLWRDCTTQLLASPDYGEVVCRYGTSQG
YQPLVDAIQKDFNQRYGLNLTDRQILITPGSQALYFLAANAFGGATETGRLKKIVLPLSPDYTGYGGICLTPEALKAYQP
TLEIDETAHRFKYRPDFEQLHFDETTGCIIFSRPCNPTGNVLSKAEVKQIADLAAPFNIPVLIDSAYGPPYPSLNYTDIA
PILGNNIVHCMSLSKAGLPGERVGIAIGDERIIQILEAFQTNVCIHSGRYGQAIAAQAIQSGALAEISVQVIRPYYQAKL
ALLQSTLDQHMPSTLPWFLHLGEGAIFAWLWLKELPISDWQLYQQLKRVGVIVVPGHSFFPGLSQDWPHKHQCLRISLTA
TDEEITIAMQRLVPVIEEVYRSNNA

Sequences:

>Translated_425_residues
MPPTLSQIGNQMSALTGVRAIMKDIIETLRANPDESFINLSAGNPVILPEVEQLWRDCTTQLLASPDYGEVVCRYGTSQG
YQPLVDAIQKDFNQRYGLNLTDRQILITPGSQALYFLAANAFGGATETGRLKKIVLPLSPDYTGYGGICLTPEALKAYQP
TLEIDETAHRFKYRPDFEQLHFDETTGCIIFSRPCNPTGNVLSKAEVKQIADLAAPFNIPVLIDSAYGPPYPSLNYTDIA
PILGNNIVHCMSLSKAGLPGERVGIAIGDERIIQILEAFQTNVCIHSGRYGQAIAAQAIQSGALAEISVQVIRPYYQAKL
ALLQSTLDQHMPSTLPWFLHLGEGAIFAWLWLKELPISDWQLYQQLKRVGVIVVPGHSFFPGLSQDWPHKHQCLRISLTA
TDEEITIAMQRLVPVIEEVYRSNNA
>Mature_424_residues
PPTLSQIGNQMSALTGVRAIMKDIIETLRANPDESFINLSAGNPVILPEVEQLWRDCTTQLLASPDYGEVVCRYGTSQGY
QPLVDAIQKDFNQRYGLNLTDRQILITPGSQALYFLAANAFGGATETGRLKKIVLPLSPDYTGYGGICLTPEALKAYQPT
LEIDETAHRFKYRPDFEQLHFDETTGCIIFSRPCNPTGNVLSKAEVKQIADLAAPFNIPVLIDSAYGPPYPSLNYTDIAP
ILGNNIVHCMSLSKAGLPGERVGIAIGDERIIQILEAFQTNVCIHSGRYGQAIAAQAIQSGALAEISVQVIRPYYQAKLA
LLQSTLDQHMPSTLPWFLHLGEGAIFAWLWLKELPISDWQLYQQLKRVGVIVVPGHSFFPGLSQDWPHKHQCLRISLTAT
DEEITIAMQRLVPVIEEVYRSNNA

Specific function: Unknown

COG id: COG3977

COG function: function code E; Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Escherichia coli, GI48994949, Length=421, Percent_Identity=36.3420427553444, Blast_Score=297, Evalue=1e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.66 [H]

Molecular weight: Translated: 47008; Mature: 46877

Theoretical pI: Translated: 5.40; Mature: 5.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPPTLSQIGNQMSALTGVRAIMKDIIETLRANPDESFINLSAGNPVILPEVEQLWRDCTT
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEECCCHHHHHHHHHH
QLLASPDYGEVVCRYGTSQGYQPLVDAIQKDFNQRYGLNLTDRQILITPGSQALYFLAAN
HHHCCCCHHHHEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCEEEEEEEC
AFGGATETGRLKKIVLPLSPDYTGYGGICLTPEALKAYQPTLEIDETAHRFKYRPDFEQL
CCCCCCCCCCEEEEEEECCCCCCCCCCEEECHHHHHHHCCCCCCCHHHHHCCCCCCHHHH
HFDETTGCIIFSRPCNPTGNVLSKAEVKQIADLAAPFNIPVLIDSAYGPPYPSLNYTDIA
CCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCH
PILGNNIVHCMSLSKAGLPGERVGIAIGDERIIQILEAFQTNVCIHSGRYGQAIAAQAIQ
HHHCCCCEEEHHHHCCCCCCCCEEEEECHHHHHHHHHHHHHCEEEECCCCCHHHHHHHHH
SGALAEISVQVIRPYYQAKLALLQSTLDQHMPSTLPWFLHLGEGAIFAWLWLKELPISDW
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEECCCCEEEEHHHHHCCCCHH
QLYQQLKRVGVIVVPGHSFFPGLSQDWPHKHQCLRISLTATDEEITIAMQRLVPVIEEVY
HHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHH
RSNNA
HCCCC
>Mature Secondary Structure 
PPTLSQIGNQMSALTGVRAIMKDIIETLRANPDESFINLSAGNPVILPEVEQLWRDCTT
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEECCCHHHHHHHHHH
QLLASPDYGEVVCRYGTSQGYQPLVDAIQKDFNQRYGLNLTDRQILITPGSQALYFLAAN
HHHCCCCHHHHEEECCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCEEEEEEEC
AFGGATETGRLKKIVLPLSPDYTGYGGICLTPEALKAYQPTLEIDETAHRFKYRPDFEQL
CCCCCCCCCCEEEEEEECCCCCCCCCCEEECHHHHHHHCCCCCCCHHHHHCCCCCCHHHH
HFDETTGCIIFSRPCNPTGNVLSKAEVKQIADLAAPFNIPVLIDSAYGPPYPSLNYTDIA
CCCCCCCEEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCH
PILGNNIVHCMSLSKAGLPGERVGIAIGDERIIQILEAFQTNVCIHSGRYGQAIAAQAIQ
HHHCCCCEEEHHHHCCCCCCCCEEEEECHHHHHHHHHHHHHCEEEECCCCCHHHHHHHHH
SGALAEISVQVIRPYYQAKLALLQSTLDQHMPSTLPWFLHLGEGAIFAWLWLKELPISDW
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHEEECCCCEEEEHHHHHCCCCHH
QLYQQLKRVGVIVVPGHSFFPGLSQDWPHKHQCLRISLTATDEEITIAMQRLVPVIEEVY
HHHHHHHHCCEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHH
RSNNA
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2825136; 8041620; 9278503 [H]