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The map label for this gene is ydjG [C]

Identifier: 158335175

GI number: 158335175

Start: 2006396

End: 2007337

Strand: Reverse

Name: ydjG [C]

Synonym: AM1_2018

Alternate gene names: 158335175

Gene position: 2007337-2006396 (Counterclockwise)

Preceding gene: 158335177

Following gene: 158335172

Centisome position: 30.86

GC content: 49.47

Gene sequence:

>942_bases
ATGACAACGAAACAACTTGGCCCTAGTGGGCCTCTGGTGTCAGCTGTGGGCATTGGCACATGGTCATGGGGCGATCGGAT
CTTTTGGGGCTATGGCGATCAGTATGGTGAGGCTGAAGTTGCTGATGCGTTTCAATCTGCGGTTCAGGCTGGAATTACCT
TGTTTGATACAGCTGAAATTTATGGATGGGGTGAGTCTGAGCGACTGTTAGGTCAGTTCTGTCGGGACTGTCAGCGTCCA
GTTTGTTTGGCGACTAAATATGGTCCGGTTCCTTGGCGTTTGGGTGAAGACGCAGTTCTTCAGGCGGTTCAAGACAGTCT
GAAACGATTGCAGGTAGATGTGATTGATTTATACCAGGTTCATTGGCCTTTCAATTTCTTTATGAGTTATGAGACTCTAT
TTCGAGCCCTGGCGAAGGCGGTTAATCAAGGGCTGATTAAAACCGTTGGTGTAAGCAACTACAGTGCTAAGCAAATGCAT
ACAGCTCATGCTTTATTGGCCGAGCAAGGGGTGTCTCTCGCCGTGAACCAGGTGCGATATTCTCTGATTACTCGCCAAGT
GGAGAGTCAAGGATTGATAGCTAAGGCCAGAGAATTAGGGGTCACCATCTTGGCCTATAGCCCCCTAGCCCAGGGGTTAC
TAACGGGTAAATATACGCCTGAACAGCTCCCGACAGGTGCTCGCAAAGCCGATCAGCGCTTTAAACCTGAGGGATTACGA
AAAGTGGCTCCAGTTACTAACTTGCTGCGTCAATTTGCGGAAGCCCATGACAAAACGATGGCGCAAGTAGCGCTGAATTG
GTTGATTGCTCAAGAAGGTGTTATTCCCATTCCAGGGGCGAAAACGGCACAGCAAGCCATAGAAAATGCGGGGACTTTGG
GATGGTCCTTAACGCCTGAAGAGGTGACTGCTTTAGAAGAAGCTAGTCGTCCCTGGTTGTGA

Upstream 100 bases:

>100_bases
ACTTACGGCTGGAGATTCCTGTTGATGAAGCCGGTAAAGTACTCCTATCTAAAGTGGTTTTTATTAAACTAGAAGTAGAA
ATATTAAGAAGTGTTTATCA

Downstream 100 bases:

>100_bases
AGCCGATTCATAACATTTAAGGTGCAGATTGGCTTTGAACCGCTTGCCGTAGATTGCCTTGATGTTGGTCTAGCAGAGCT
TGGCCCTGATCGGTAGAGAG

Product: oxidoreductase, aldo reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 313; Mature: 312

Protein sequence:

>313_residues
MTTKQLGPSGPLVSAVGIGTWSWGDRIFWGYGDQYGEAEVADAFQSAVQAGITLFDTAEIYGWGESERLLGQFCRDCQRP
VCLATKYGPVPWRLGEDAVLQAVQDSLKRLQVDVIDLYQVHWPFNFFMSYETLFRALAKAVNQGLIKTVGVSNYSAKQMH
TAHALLAEQGVSLAVNQVRYSLITRQVESQGLIAKARELGVTILAYSPLAQGLLTGKYTPEQLPTGARKADQRFKPEGLR
KVAPVTNLLRQFAEAHDKTMAQVALNWLIAQEGVIPIPGAKTAQQAIENAGTLGWSLTPEEVTALEEASRPWL

Sequences:

>Translated_313_residues
MTTKQLGPSGPLVSAVGIGTWSWGDRIFWGYGDQYGEAEVADAFQSAVQAGITLFDTAEIYGWGESERLLGQFCRDCQRP
VCLATKYGPVPWRLGEDAVLQAVQDSLKRLQVDVIDLYQVHWPFNFFMSYETLFRALAKAVNQGLIKTVGVSNYSAKQMH
TAHALLAEQGVSLAVNQVRYSLITRQVESQGLIAKARELGVTILAYSPLAQGLLTGKYTPEQLPTGARKADQRFKPEGLR
KVAPVTNLLRQFAEAHDKTMAQVALNWLIAQEGVIPIPGAKTAQQAIENAGTLGWSLTPEEVTALEEASRPWL
>Mature_312_residues
TTKQLGPSGPLVSAVGIGTWSWGDRIFWGYGDQYGEAEVADAFQSAVQAGITLFDTAEIYGWGESERLLGQFCRDCQRPV
CLATKYGPVPWRLGEDAVLQAVQDSLKRLQVDVIDLYQVHWPFNFFMSYETLFRALAKAVNQGLIKTVGVSNYSAKQMHT
AHALLAEQGVSLAVNQVRYSLITRQVESQGLIAKARELGVTILAYSPLAQGLLTGKYTPEQLPTGARKADQRFKPEGLRK
VAPVTNLLRQFAEAHDKTMAQVALNWLIAQEGVIPIPGAKTAQQAIENAGTLGWSLTPEEVTALEEASRPWL

Specific function: Unknown

COG id: COG0667

COG function: function code C; Predicted oxidoreductases (related to aryl-alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436962, Length=311, Percent_Identity=28.2958199356913, Blast_Score=106, Evalue=3e-23,
Organism=Homo sapiens, GI27436964, Length=311, Percent_Identity=28.2958199356913, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI27436966, Length=311, Percent_Identity=28.2958199356913, Blast_Score=105, Evalue=4e-23,
Organism=Homo sapiens, GI27436969, Length=311, Percent_Identity=27.3311897106109, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI27436971, Length=327, Percent_Identity=28.1345565749235, Blast_Score=101, Evalue=9e-22,
Organism=Homo sapiens, GI4504825, Length=308, Percent_Identity=27.2727272727273, Blast_Score=100, Evalue=1e-21,
Organism=Homo sapiens, GI223718702, Length=285, Percent_Identity=33.3333333333333, Blast_Score=92, Evalue=8e-19,
Organism=Homo sapiens, GI41327764, Length=329, Percent_Identity=31.9148936170213, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI41152114, Length=226, Percent_Identity=34.9557522123894, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI223468663, Length=329, Percent_Identity=25.8358662613982, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI24497577, Length=335, Percent_Identity=25.3731343283582, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI5174391, Length=335, Percent_Identity=25.3731343283582, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI291291012, Length=238, Percent_Identity=26.890756302521, Blast_Score=71, Evalue=1e-12,
Organism=Escherichia coli, GI1788070, Length=329, Percent_Identity=30.3951367781155, Blast_Score=124, Evalue=7e-30,
Organism=Escherichia coli, GI1788081, Length=309, Percent_Identity=32.6860841423948, Blast_Score=124, Evalue=8e-30,
Organism=Escherichia coli, GI87081735, Length=320, Percent_Identity=30, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI1789375, Length=313, Percent_Identity=30.6709265175719, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI87082198, Length=308, Percent_Identity=25.6493506493506, Blast_Score=93, Evalue=2e-20,
Organism=Escherichia coli, GI1789199, Length=341, Percent_Identity=31.9648093841642, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1786400, Length=299, Percent_Identity=25.4180602006689, Blast_Score=77, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17564128, Length=324, Percent_Identity=28.7037037037037, Blast_Score=98, Evalue=4e-21,
Organism=Caenorhabditis elegans, GI71998625, Length=303, Percent_Identity=26.7326732673267, Blast_Score=79, Evalue=4e-15,
Organism=Caenorhabditis elegans, GI17566692, Length=317, Percent_Identity=23.9747634069401, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17537075, Length=332, Percent_Identity=24.6987951807229, Blast_Score=65, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6325169, Length=344, Percent_Identity=26.1627906976744, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6325384, Length=258, Percent_Identity=27.5193798449612, Blast_Score=83, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6319958, Length=296, Percent_Identity=25.6756756756757, Blast_Score=77, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6323998, Length=323, Percent_Identity=25.3869969040248, Blast_Score=77, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6320079, Length=311, Percent_Identity=24.1157556270096, Blast_Score=69, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6322615, Length=218, Percent_Identity=25.2293577981651, Blast_Score=67, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24644950, Length=328, Percent_Identity=27.7439024390244, Blast_Score=97, Evalue=1e-20,
Organism=Drosophila melanogaster, GI221378297, Length=348, Percent_Identity=27.0114942528736, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI24657054, Length=328, Percent_Identity=24.390243902439, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24646159, Length=252, Percent_Identity=28.968253968254, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI20129731, Length=325, Percent_Identity=24.3076923076923, Blast_Score=72, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 34365; Mature: 34233

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00062 ALDOKETO_REDUCTASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTKQLGPSGPLVSAVGIGTWSWGDRIFWGYGDQYGEAEVADAFQSAVQAGITLFDTAEI
CCCCCCCCCCCCEEEECCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCEEEECHHH
YGWGESERLLGQFCRDCQRPVCLATKYGPVPWRLGEDAVLQAVQDSLKRLQVDVIDLYQV
CCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
HWPFNFFMSYETLFRALAKAVNQGLIKTVGVSNYSAKQMHTAHALLAEQGVSLAVNQVRY
HCCHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHH
SLITRQVESQGLIAKARELGVTILAYSPLAQGLLTGKYTPEQLPTGARKADQRFKPEGLR
HHHHHHHHHCCHHHHHHHCCEEEEEECHHHHHHHCCCCCHHHCCCCHHHHHHCCCHHHHH
KVAPVTNLLRQFAEAHDKTMAQVALNWLIAQEGVIPIPGAKTAQQAIENAGTLGWSLTPE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHCCCCCCCCCHH
EVTALEEASRPWL
HHHHHHHHCCCCC
>Mature Secondary Structure 
TTKQLGPSGPLVSAVGIGTWSWGDRIFWGYGDQYGEAEVADAFQSAVQAGITLFDTAEI
CCCCCCCCCCCEEEECCCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHCCEEEECHHH
YGWGESERLLGQFCRDCQRPVCLATKYGPVPWRLGEDAVLQAVQDSLKRLQVDVIDLYQV
CCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
HWPFNFFMSYETLFRALAKAVNQGLIKTVGVSNYSAKQMHTAHALLAEQGVSLAVNQVRY
HCCHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHH
SLITRQVESQGLIAKARELGVTILAYSPLAQGLLTGKYTPEQLPTGARKADQRFKPEGLR
HHHHHHHHHCCHHHHHHHCCEEEEEECHHHHHHHCCCCCHHHCCCCHHHHHHCCCHHHHH
KVAPVTNLLRQFAEAHDKTMAQVALNWLIAQEGVIPIPGAKTAQQAIENAGTLGWSLTPE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCHHHHHHHHHCCCCCCCCCHH
EVTALEEASRPWL
HHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]