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The map label for this gene is yyxA [H]

Identifier: 158335104

GI number: 158335104

Start: 1938893

End: 1940674

Strand: Direct

Name: yyxA [H]

Synonym: AM1_1945

Alternate gene names: 158335104

Gene position: 1938893-1940674 (Clockwise)

Preceding gene: 158335103

Following gene: 158335105

Centisome position: 29.81

GC content: 51.57

Gene sequence:

>1782_bases
ATGGTGTTTAAAAGTTTTACGTATCCAGCTGTGGCGTTTATGGGGGTTGCAGCCGTTGCGATTGCACCTCATCCCGCCCA
AGCCCTCAGTCCTGACCAAATTAGTGGCATCGCCAAGCAAGTCACGGTGCTCATTGATGGTCAAAATCCTGGATCAGGGG
TCATTATCGATCGGAATGGCGATACCTATACGGTCCTCACGGCGTTTCATGTGGTTGGCACCCCCGATGAATACGATGTC
GTCACCCCCACCGATCAACGCTACAAATTAGACTACCAAACCGTTAAACGCTTGCCGGGTGTTGATCTAGCGGTTCTCAA
ATTTAAAAGCAATAAAACCTATAAGGTTGCCGACCTGGGGAACTCCACCCAAGTACAAGAAGGAAAGCCCATCTATGTGG
CCGGATTTCCCCAACCCACCCAAGCCATTAACTTATCCATTTATCGGTTTACAGAAGGACGACTCACGGCCAACTCATCG
AAACCCTTAGCCGATGGTTATGCCCTGGTTTATAACAATTCCACTCGACCCGGCATGAGTGGTGGCCCCGTCCTCAATGA
CCAAGGTGCCCTAGTCGGCATTCATGGCCGCTCGGATGCTCAGCAACAGGGCAATGTCTACTTCAAAAATGACACCAACT
TGGGGGTTCCCATCGATACCTTCTCAATGATGGCCCCTCAAATAGGGGTGAAGTTAGATTCAATCCCTGGATCCTCAACG
CCTAGCCCATCCATTCCCGCTACAGCTCCTACCCGCCCACCAAGACCGCCGGTCCCCCAAGGACCTAGGGCAGGAGATTT
TTACCTCCAGGCCACTGATAAGTTGCAACGGGGAGATTCCCAAGGTGCTTTGCGAGATCTGAACCAAGCCATTAGCCTGA
ATCCCAATTATGCCAATGCCTATGGCGATCGAGCCACGATCAAATTTCAGCAGGGCGATCGCAGAGGAGCACTTGCAGAC
TTAGACCAAGCCATCCAGATTGATCCTCAGTTAGCAGATGCCTATGGCATTCGTGGACTATATCGAGTGGTGACGGGCAA
TATTCGCGGCGCTCAGTCCGATGTAGAGAAAGCGGTCCGTCTCAAACCTGAGATCGGCTATGCCTCTCGGGGCGTGGTGC
GCTGGTATCGCAGTGATTTGGCAGGCGCTCAATCCGATTTTGACCAGGCGCTCAGTCTCAAGGATTCGTTCAAAGATGCC
TATGCCGTCCACTATTTTCGTGGGTTTGTCCGTTGGCAGCTGGGCAATTTTGATGGTGCCCTCCAGGATCTCAATCGCTC
TATTCAGCTGAACCCCAAATATCTAGAAGCCGTCGGCGTTCGAGGGATTCTGCGATTCCAAATGGGGGATGAGGTCGGCG
CTTTACGAGACTTTGATGAAGGCATTCGCATCAACACGGGCAGTAGTGATATCTACACCATCCGCGGCATGATTCGCCTC
ACCCAGGGCGATAGCCAAGGCGCAATCTCTGATTTTGATCAAGTGATTCGCATCCAGCCCGGCAACGTCGCTTTAGCAGA
TATGTATGGCAGTCGGGGGATTGCCTACTTCCAAGCGGGTAATGATGAACAAGCCTTAGCTAGTCTCCGCCAGGCCGTTC
AACTTGCCAAAGATGCCAGCAGCCGAGAGTCCTATCAGAAATTAGGTAACGCCATCAGTAACTTACAATCGCAACCTGCA
TTACGTCCTAAGATGAAGGCCTATATTCAAACCTTTATGCAAAGCTACCTGAAACGATATATCGGCCAGTATGTGCAGTC
CTATCGTCCGTTGCAGGGCTAA

Upstream 100 bases:

>100_bases
GTTTTAGGCTATCAAACGACACCTTAACCCTGCTGAAAGACATCCGGTGGTCTATTTTTCTCCGTGCTAGAGTATGGTCT
GGTGGCGATCTTTCAGCATT

Downstream 100 bases:

>100_bases
GGGCAACCATGAGGTCCAGCCAGAAGGGATTCTCCACTCATGTTGGTAGAGGTTAGCCCTCTACAGGCCCCAGACTTAGC
CGATGCAGTGGCCTTAGATC

Product: TPR domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 593; Mature: 593

Protein sequence:

>593_residues
MVFKSFTYPAVAFMGVAAVAIAPHPAQALSPDQISGIAKQVTVLIDGQNPGSGVIIDRNGDTYTVLTAFHVVGTPDEYDV
VTPTDQRYKLDYQTVKRLPGVDLAVLKFKSNKTYKVADLGNSTQVQEGKPIYVAGFPQPTQAINLSIYRFTEGRLTANSS
KPLADGYALVYNNSTRPGMSGGPVLNDQGALVGIHGRSDAQQQGNVYFKNDTNLGVPIDTFSMMAPQIGVKLDSIPGSST
PSPSIPATAPTRPPRPPVPQGPRAGDFYLQATDKLQRGDSQGALRDLNQAISLNPNYANAYGDRATIKFQQGDRRGALAD
LDQAIQIDPQLADAYGIRGLYRVVTGNIRGAQSDVEKAVRLKPEIGYASRGVVRWYRSDLAGAQSDFDQALSLKDSFKDA
YAVHYFRGFVRWQLGNFDGALQDLNRSIQLNPKYLEAVGVRGILRFQMGDEVGALRDFDEGIRINTGSSDIYTIRGMIRL
TQGDSQGAISDFDQVIRIQPGNVALADMYGSRGIAYFQAGNDEQALASLRQAVQLAKDASSRESYQKLGNAISNLQSQPA
LRPKMKAYIQTFMQSYLKRYIGQYVQSYRPLQG

Sequences:

>Translated_593_residues
MVFKSFTYPAVAFMGVAAVAIAPHPAQALSPDQISGIAKQVTVLIDGQNPGSGVIIDRNGDTYTVLTAFHVVGTPDEYDV
VTPTDQRYKLDYQTVKRLPGVDLAVLKFKSNKTYKVADLGNSTQVQEGKPIYVAGFPQPTQAINLSIYRFTEGRLTANSS
KPLADGYALVYNNSTRPGMSGGPVLNDQGALVGIHGRSDAQQQGNVYFKNDTNLGVPIDTFSMMAPQIGVKLDSIPGSST
PSPSIPATAPTRPPRPPVPQGPRAGDFYLQATDKLQRGDSQGALRDLNQAISLNPNYANAYGDRATIKFQQGDRRGALAD
LDQAIQIDPQLADAYGIRGLYRVVTGNIRGAQSDVEKAVRLKPEIGYASRGVVRWYRSDLAGAQSDFDQALSLKDSFKDA
YAVHYFRGFVRWQLGNFDGALQDLNRSIQLNPKYLEAVGVRGILRFQMGDEVGALRDFDEGIRINTGSSDIYTIRGMIRL
TQGDSQGAISDFDQVIRIQPGNVALADMYGSRGIAYFQAGNDEQALASLRQAVQLAKDASSRESYQKLGNAISNLQSQPA
LRPKMKAYIQTFMQSYLKRYIGQYVQSYRPLQG
>Mature_593_residues
MVFKSFTYPAVAFMGVAAVAIAPHPAQALSPDQISGIAKQVTVLIDGQNPGSGVIIDRNGDTYTVLTAFHVVGTPDEYDV
VTPTDQRYKLDYQTVKRLPGVDLAVLKFKSNKTYKVADLGNSTQVQEGKPIYVAGFPQPTQAINLSIYRFTEGRLTANSS
KPLADGYALVYNNSTRPGMSGGPVLNDQGALVGIHGRSDAQQQGNVYFKNDTNLGVPIDTFSMMAPQIGVKLDSIPGSST
PSPSIPATAPTRPPRPPVPQGPRAGDFYLQATDKLQRGDSQGALRDLNQAISLNPNYANAYGDRATIKFQQGDRRGALAD
LDQAIQIDPQLADAYGIRGLYRVVTGNIRGAQSDVEKAVRLKPEIGYASRGVVRWYRSDLAGAQSDFDQALSLKDSFKDA
YAVHYFRGFVRWQLGNFDGALQDLNRSIQLNPKYLEAVGVRGILRFQMGDEVGALRDFDEGIRINTGSSDIYTIRGMIRL
TQGDSQGAISDFDQVIRIQPGNVALADMYGSRGIAYFQAGNDEQALASLRQAVQLAKDASSRESYQKLGNAISNLQSQPA
LRPKMKAYIQTFMQSYLKRYIGQYVQSYRPLQG

Specific function: Unknown

COG id: COG0457

COG function: function code R; FOG: TPR repeat

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Homo sapiens, GI170784867, Length=307, Percent_Identity=25.0814332247557, Blast_Score=80, Evalue=6e-15,
Organism=Homo sapiens, GI54607135, Length=269, Percent_Identity=25.2788104089219, Blast_Score=74, Evalue=5e-13,
Organism=Homo sapiens, GI32307148, Length=278, Percent_Identity=23.7410071942446, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI32307150, Length=278, Percent_Identity=23.7410071942446, Blast_Score=72, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00089 Trypsin [H]

EC number: NA

Molecular weight: Translated: 64668; Mature: 64668

Theoretical pI: Translated: 9.49; Mature: 9.49

Prosite motif: PS50005 TPR L=RR ; PS50293 TPR_REGION

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVFKSFTYPAVAFMGVAAVAIAPHPAQALSPDQISGIAKQVTVLIDGQNPGSGVIIDRNG
CCCCCCCHHHHHHHHHHHHEECCCCHHHCCCHHHHHHEEEEEEEEECCCCCCEEEEECCC
DTYTVLTAFHVVGTPDEYDVVTPTDQRYKLDYQTVKRLPGVDLAVLKFKSNKTYKVADLG
CEEEEEEEEEEECCCCCCCEECCCCCCEEECHHHHHHCCCCCEEEEEEECCCEEEEEECC
NSTQVQEGKPIYVAGFPQPTQAINLSIYRFTEGRLTANSSKPLADGYALVYNNSTRPGMS
CCCCCCCCCEEEEECCCCCCCEEEEEEEEEECCEEECCCCCCCCCCEEEEEECCCCCCCC
GGPVLNDQGALVGIHGRSDAQQQGNVYFKNDTNLGVPIDTFSMMAPQIGVKLDSIPGSST
CCCEECCCCCEEEEECCCCHHHCCCEEEECCCCCCCCCHHHHHHCCHHCEEEECCCCCCC
PSPSIPATAPTRPPRPPVPQGPRAGDFYLQATDKLQRGDSQGALRDLNQAISLNPNYANA
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECHHHHCCCCCCHHHHHHHHEECCCCCCCC
YGDRATIKFQQGDRRGALADLDQAIQIDPQLADAYGIRGLYRVVTGNIRGAQSDVEKAVR
CCCCEEEEEECCCCCCCHHHCHHHEECCCHHHHHHHHHHEEHHHCCCCCCCHHHHHHHHH
LKPEIGYASRGVVRWYRSDLAGAQSDFDQALSLKDSFKDAYAVHYFRGFVRWQLGNFDGA
CCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHH
LQDLNRSIQLNPKYLEAVGVRGILRFQMGDEVGALRDFDEGIRINTGSSDIYTIRGMIRL
HHHCCCCEECCHHHHHHHCCCEEEEEECCCCCCCHHCCCCCCEEECCCCCEEEEEEEEEE
TQGDSQGAISDFDQVIRIQPGNVALADMYGSRGIAYFQAGNDEQALASLRQAVQLAKDAS
ECCCCCCCHHHHHHEEEECCCCEEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHCCH
SRESYQKLGNAISNLQSQPALRPKMKAYIQTFMQSYLKRYIGQYVQSYRPLQG
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MVFKSFTYPAVAFMGVAAVAIAPHPAQALSPDQISGIAKQVTVLIDGQNPGSGVIIDRNG
CCCCCCCHHHHHHHHHHHHEECCCCHHHCCCHHHHHHEEEEEEEEECCCCCCEEEEECCC
DTYTVLTAFHVVGTPDEYDVVTPTDQRYKLDYQTVKRLPGVDLAVLKFKSNKTYKVADLG
CEEEEEEEEEEECCCCCCCEECCCCCCEEECHHHHHHCCCCCEEEEEEECCCEEEEEECC
NSTQVQEGKPIYVAGFPQPTQAINLSIYRFTEGRLTANSSKPLADGYALVYNNSTRPGMS
CCCCCCCCCEEEEECCCCCCCEEEEEEEEEECCEEECCCCCCCCCCEEEEEECCCCCCCC
GGPVLNDQGALVGIHGRSDAQQQGNVYFKNDTNLGVPIDTFSMMAPQIGVKLDSIPGSST
CCCEECCCCCEEEEECCCCHHHCCCEEEECCCCCCCCCHHHHHHCCHHCEEEECCCCCCC
PSPSIPATAPTRPPRPPVPQGPRAGDFYLQATDKLQRGDSQGALRDLNQAISLNPNYANA
CCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECHHHHCCCCCCHHHHHHHHEECCCCCCCC
YGDRATIKFQQGDRRGALADLDQAIQIDPQLADAYGIRGLYRVVTGNIRGAQSDVEKAVR
CCCCEEEEEECCCCCCCHHHCHHHEECCCHHHHHHHHHHEEHHHCCCCCCCHHHHHHHHH
LKPEIGYASRGVVRWYRSDLAGAQSDFDQALSLKDSFKDAYAVHYFRGFVRWQLGNFDGA
CCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCHH
LQDLNRSIQLNPKYLEAVGVRGILRFQMGDEVGALRDFDEGIRINTGSSDIYTIRGMIRL
HHHCCCCEECCHHHHHHHCCCEEEEEECCCCCCCHHCCCCCCEEECCCCCEEEEEEEEEE
TQGDSQGAISDFDQVIRIQPGNVALADMYGSRGIAYFQAGNDEQALASLRQAVQLAKDAS
ECCCCCCCHHHHHHEEEECCCCEEEEEECCCCCEEEEECCCCHHHHHHHHHHHHHHHCCH
SRESYQKLGNAISNLQSQPALRPKMKAYIQTFMQSYLKRYIGQYVQSYRPLQG
HHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 8113162 [H]