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The map label for this gene is aroQ

Identifier: 158335102

GI number: 158335102

Start: 1936500

End: 1936949

Strand: Direct

Name: aroQ

Synonym: AM1_1943

Alternate gene names: 158335102

Gene position: 1936500-1936949 (Clockwise)

Preceding gene: 158335101

Following gene: 158335103

Centisome position: 29.78

GC content: 47.33

Gene sequence:

>450_bases
GTGAGCCGTCCTAGCATTCTGGTCCTGCACGGTCCCAATCTAAATCTGCTCGGCCAGCGTGAGCCTGGTATTTACGGTTC
AGTCACCCTAGAAAAAATTAATCAGCAACTGCTATCTCTAGCAGAATCGCTGAAATGCAATATTGAATTTTATCAGTCCA
ACCATGAAGGCAACCTAGTCGATTCCATTCAGGAAGCCTTGGGTTGTCATAACGGCATTCTCATCAATGCAGCTGCCTAT
ACCCACACTAGTGTTGCGATTCGTGATGCTTTAGCGGCCGTCGCGATTCCCGCCGTCGAAGTCCATCTCAGTAATATTTA
TCGGCGCGAAGACTTTCGACACCATTCCTTTATTGCTCCCATCGTAATCGGTCAAATTAGCGGATTCGGTGCCCAGAGCT
ACTCTTTAGGCCTTCAAGCCTTAATTCACCACTTACAAACCCAGACTTAA

Upstream 100 bases:

>100_bases
TCGTTAAACATCTAATTTATCCATCTTGCTGCTACACAGTGTTTATAACCATCATGTTCTGAATATTGTGGCCAACCAGT
CTTTTTTTAACTAATTTTCT

Downstream 100 bases:

>100_bases
TCCTGCTCTAGGCAATTCGTTACGAAGTCTAGACTATAATGAACTTTTGTTGCTGAAATACGGGATTGTCAAGGGAGAAT
TCCGTGAGCCTGCTGTTGGT

Product: 3-dehydroquinate dehydratase

Products: NA

Alternate protein names: 3-dehydroquinase; Type II DHQase

Number of amino acids: Translated: 149; Mature: 148

Protein sequence:

>149_residues
MSRPSILVLHGPNLNLLGQREPGIYGSVTLEKINQQLLSLAESLKCNIEFYQSNHEGNLVDSIQEALGCHNGILINAAAY
THTSVAIRDALAAVAIPAVEVHLSNIYRREDFRHHSFIAPIVIGQISGFGAQSYSLGLQALIHHLQTQT

Sequences:

>Translated_149_residues
MSRPSILVLHGPNLNLLGQREPGIYGSVTLEKINQQLLSLAESLKCNIEFYQSNHEGNLVDSIQEALGCHNGILINAAAY
THTSVAIRDALAAVAIPAVEVHLSNIYRREDFRHHSFIAPIVIGQISGFGAQSYSLGLQALIHHLQTQT
>Mature_148_residues
SRPSILVLHGPNLNLLGQREPGIYGSVTLEKINQQLLSLAESLKCNIEFYQSNHEGNLVDSIQEALGCHNGILINAAAYT
HTSVAIRDALAAVAIPAVEVHLSNIYRREDFRHHSFIAPIVIGQISGFGAQSYSLGLQALIHHLQTQT

Specific function: Catalyzes a trans-dehydration via an enolate intermediate

COG id: COG0757

COG function: function code E; 3-dehydroquinate dehydratase II

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the type-II 3-dehydroquinase family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROQ_ACAM1 (B0CEJ4)

Other databases:

- EMBL:   CP000828
- RefSeq:   YP_001516274.1
- ProteinModelPortal:   B0CEJ4
- SMR:   B0CEJ4
- GeneID:   5680758
- GenomeReviews:   CP000828_GR
- KEGG:   amr:AM1_1943
- HOGENOM:   HBG284657
- OMA:   HSYIAPI
- ProtClustDB:   PRK05395
- BioCyc:   AMAR329726:AM1_1943-MONOMER
- HAMAP:   MF_00169
- InterPro:   IPR001874
- InterPro:   IPR018509
- Gene3D:   G3DSA:3.40.50.9100
- PANTHER:   PTHR21272
- PIRSF:   PIRSF001399
- ProDom:   PD004527
- TIGRFAMs:   TIGR01088

Pfam domain/function: PF01220 DHquinase_II; SSF52304 DHquinase_II

EC number: =4.2.1.10

Molecular weight: Translated: 16261; Mature: 16130

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS01029 DEHYDROQUINASE_II

Important sites: ACT_SITE 25-25 ACT_SITE 102-102 BINDING 76-76 BINDING 82-82 BINDING 89-89 BINDING 113-113

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRPSILVLHGPNLNLLGQREPGIYGSVTLEKINQQLLSLAESLKCNIEFYQSNHEGNLV
CCCCCEEEEECCCCCEEECCCCCCEEEHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCHH
DSIQEALGCHNGILINAAAYTHTSVAIRDALAAVAIPAVEVHLSNIYRREDFRHHSFIAP
HHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
IVIGQISGFGAQSYSLGLQALIHHLQTQT
HHHCCCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SRPSILVLHGPNLNLLGQREPGIYGSVTLEKINQQLLSLAESLKCNIEFYQSNHEGNLV
CCCCEEEEECCCCCEEECCCCCCEEEHHHHHHHHHHHHHHHHHEEEEEEEECCCCCCHH
DSIQEALGCHNGILINAAAYTHTSVAIRDALAAVAIPAVEVHLSNIYRREDFRHHSFIAP
HHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
IVIGQISGFGAQSYSLGLQALIHHLQTQT
HHHCCCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA