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The map label for this gene is trx [H]

Identifier: 158335030

GI number: 158335030

Start: 1853399

End: 1853722

Strand: Direct

Name: trx [H]

Synonym: AM1_1868

Alternate gene names: 158335030

Gene position: 1853399-1853722 (Clockwise)

Preceding gene: 158335029

Following gene: 158335031

Centisome position: 28.5

GC content: 44.14

Gene sequence:

>324_bases
ATGTCATCAGCTGCCCCAGTCACAGATGCCACATTCAAAGAAGAAGTCATTGAAAGTGATGTTCCTGTTCTTGTTGATTT
TTGGGCACCTTGGTGCGGACCTTGTCGGATGGTTGCTCCCGTCGTTGATGAAATCTCTGAGCAATATAAAGGCCAAGTCA
AGGTTGTAAAAATCAACACGGATGAAAATCCCAATGTTGCCAGTCAGTACGGAATTCGTAGTATTCCGACTTTAATGGTC
TTTAAGGGCGGGCAGCGTGTCGATATGGTTGTAGGAGCTGTTCCTAAAACCACTTTGGCCAGTACTTTAGATAAGTATCT
CTAA

Upstream 100 bases:

>100_bases
TAGGCATTTTGATTGTTAATTTTCTGTTTATGTCTAGGTGGGGTTGAACCTGCTATGGTACAAATCGTAGATAAGCTACA
GTCGATAAAGGTTTCTAAGC

Downstream 100 bases:

>100_bases
TTTTTCAGGTTTTTCGGGTTCTAGCATGGAATCCGTTCGCTGCAACCCATCTTTGCAGTTCATTTAAGTTATAGAAGCGG
TCCTTCGCCAATAAACTAAG

Product: thioredoxin

Products: NA

Alternate protein names: Trx-1; Thioredoxin-M [H]

Number of amino acids: Translated: 107; Mature: 106

Protein sequence:

>107_residues
MSSAAPVTDATFKEEVIESDVPVLVDFWAPWCGPCRMVAPVVDEISEQYKGQVKVVKINTDENPNVASQYGIRSIPTLMV
FKGGQRVDMVVGAVPKTTLASTLDKYL

Sequences:

>Translated_107_residues
MSSAAPVTDATFKEEVIESDVPVLVDFWAPWCGPCRMVAPVVDEISEQYKGQVKVVKINTDENPNVASQYGIRSIPTLMV
FKGGQRVDMVVGAVPKTTLASTLDKYL
>Mature_106_residues
SSAAPVTDATFKEEVIESDVPVLVDFWAPWCGPCRMVAPVVDEISEQYKGQVKVVKINTDENPNVASQYGIRSIPTLMVF
KGGQRVDMVVGAVPKTTLASTLDKYL

Specific function: Participates in various redox reactions through the reversible oxidation of its active center dithiol to a disulfide and catalyzes dithiol-disulfide exchange reactions [H]

COG id: NA

COG function: NA

Gene ontology:
GO:0006662: Thioredoxin
GO:0009055: Thioredoxin
GO:0015035: Thioredoxin
GO:0045454: Thioredoxin

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Homo sapiens, GI21361403, Length=96, Percent_Identity=33.3333333333333, Blast_Score=77, Evalue=3e-15,
Organism=Homo sapiens, GI5031973, Length=105, Percent_Identity=35.2380952380952, Blast_Score=73, Evalue=4e-14,
Organism=Homo sapiens, GI50592994, Length=86, Percent_Identity=38.3720930232558, Blast_Score=69, Evalue=9e-13,
Organism=Homo sapiens, GI21361657, Length=106, Percent_Identity=30.188679245283, Blast_Score=65, Evalue=1e-11,
Organism=Homo sapiens, GI42794771, Length=84, Percent_Identity=33.3333333333333, Blast_Score=63, Evalue=4e-11,
Organism=Homo sapiens, GI224493972, Length=84, Percent_Identity=33.3333333333333, Blast_Score=63, Evalue=5e-11,
Organism=Escherichia coli, GI87082331, Length=101, Percent_Identity=49.5049504950495, Blast_Score=120, Evalue=2e-29,
Organism=Escherichia coli, GI1788936, Length=94, Percent_Identity=48.936170212766, Blast_Score=115, Evalue=8e-28,
Organism=Escherichia coli, GI87081747, Length=96, Percent_Identity=34.375, Blast_Score=74, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI212646193, Length=96, Percent_Identity=38.5416666666667, Blast_Score=83, Evalue=3e-17,
Organism=Caenorhabditis elegans, GI17507705, Length=71, Percent_Identity=40.8450704225352, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17510299, Length=84, Percent_Identity=42.8571428571429, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71998175, Length=84, Percent_Identity=40.4761904761905, Blast_Score=74, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17509965, Length=72, Percent_Identity=38.8888888888889, Blast_Score=70, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI115532378, Length=72, Percent_Identity=38.8888888888889, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI115532380, Length=72, Percent_Identity=38.8888888888889, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17544108, Length=72, Percent_Identity=38.8888888888889, Blast_Score=67, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17554386, Length=82, Percent_Identity=37.8048780487805, Blast_Score=66, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI71980565, Length=72, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17556044, Length=78, Percent_Identity=34.6153846153846, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71980562, Length=72, Percent_Identity=33.3333333333333, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17549970, Length=80, Percent_Identity=32.5, Blast_Score=62, Evalue=7e-11,
Organism=Saccharomyces cerevisiae, GI6323072, Length=82, Percent_Identity=45.1219512195122, Blast_Score=82, Evalue=2e-17,
Organism=Saccharomyces cerevisiae, GI6321648, Length=87, Percent_Identity=43.6781609195402, Blast_Score=80, Evalue=8e-17,
Organism=Saccharomyces cerevisiae, GI6319925, Length=94, Percent_Identity=31.9148936170213, Blast_Score=70, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24639826, Length=91, Percent_Identity=38.4615384615385, Blast_Score=89, Evalue=5e-19,
Organism=Drosophila melanogaster, GI28573567, Length=98, Percent_Identity=35.7142857142857, Blast_Score=78, Evalue=1e-15,
Organism=Drosophila melanogaster, GI17648013, Length=74, Percent_Identity=41.8918918918919, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24583090, Length=74, Percent_Identity=41.8918918918919, Blast_Score=75, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24664269, Length=82, Percent_Identity=40.2439024390244, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI19921434, Length=80, Percent_Identity=33.75, Blast_Score=69, Evalue=4e-13,
Organism=Drosophila melanogaster, GI24639068, Length=93, Percent_Identity=29.0322580645161, Blast_Score=65, Evalue=6e-12,
Organism=Drosophila melanogaster, GI24664525, Length=98, Percent_Identity=30.6122448979592, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: 3,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR013766
- InterPro:   IPR012335 [H]

Pfam domain/function: PF00085 Thioredoxin [H]

EC number: NA

Molecular weight: Translated: 11676; Mature: 11544

Theoretical pI: Translated: 4.54; Mature: 4.54

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSAAPVTDATFKEEVIESDVPVLVDFWAPWCGPCRMVAPVVDEISEQYKGQVKVVKINT
CCCCCCCCCHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECC
DENPNVASQYGIRSIPTLMVFKGGQRVDMVVGAVPKTTLASTLDKYL
CCCCCHHHHCCCCCCCEEEEECCCCEEEHEECCCCHHHHHHHHHHCC
>Mature Secondary Structure 
SSAAPVTDATFKEEVIESDVPVLVDFWAPWCGPCRMVAPVVDEISEQYKGQVKVVKINT
CCCCCCCCHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEECC
DENPNVASQYGIRSIPTLMVFKGGQRVDMVVGAVPKTTLASTLDKYL
CCCCCHHHHCCCCCCCEEEEECCCCEEEHEECCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Reduction reactions; participates in dithiol-disulfide exchange reactions [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3096973; 3926769 [H]