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The map label for this gene is csgA [H]

Identifier: 158335017

GI number: 158335017

Start: 1842348

End: 1843013

Strand: Direct

Name: csgA [H]

Synonym: AM1_1855

Alternate gene names: 158335017

Gene position: 1842348-1843013 (Clockwise)

Preceding gene: 158335012

Following gene: 158335019

Centisome position: 28.33

GC content: 48.95

Gene sequence:

>666_bases
ATGGCAACTTATTTAGTGACCGGTGCCAATCGCGGTATTGGCTTAGAATATTGCCGACAGCTCCAGCAACGGGGTGACAC
AGTTATTGCCGCCTGTCGCACCTCATCACCTGAGTTAGAAGCCCTTGGCATTCAGATTGAAACTCAAGTGGATATCACTT
CAGACACCGCTGTGGCCGATTTCAAGCAGCGGTTGGCAGGGCAGTCCCTAGATGGATTAATCAATAATGCGGGGATGATT
GATCGAGTCACTTTGGAGGACCTAAATATTGAAAGTATTCGCCGCCAATACGAAGTGAATGCCATTGGCCCCTTACGTCT
AACTCATGCTCTCTTGCCCAATCTTCCATCGGGTTCCAAGGTGATTCTGATGACGAGCCGGATGGGCTCGATTGGTGACA
ACACCTCTGGTAGCTCCTATGGCTATCGCATGTCTAAAGTCGCTCTTTGCATGGCGGGGAAATCTTTATCTCATGATCTC
AAACCAAAAGGGATAGCTGTAGCGATTCTGCATCCTGGCTTGGTTCAGACTCGAATGACCCGCTTTAATGCTAAAGGAAT
TACCCCGGAGCAATCCGTCAATGGACTATTGGAACGCATCGATCAGTTGACGCTAGACAATACAGGTACGTTCTGGCATG
CCAATGGAGAGGTATTGCCCTGGTAA

Upstream 100 bases:

>100_bases
AACATCTCCCATCTTAATGATGATGGCTCGACCAGACAGGTCTACCGGTTCCAAGGTCTTGTATTTTATGTAACTTGATA
GGAGTGTACAGAATTTTCCT

Downstream 100 bases:

>100_bases
AAGGGTGTTCAACAGGCGTTACGGTTGTGCTCGCCGCCAAAATTCAACATAAAATACTGCATCTTCCCTAGGTTGAACAT
CGTGTTGGACTTCGGGCAGA

Product: short chain dehydrogenase/reductase family oxidoreductase

Products: NA

Alternate protein names: C signal [H]

Number of amino acids: Translated: 221; Mature: 220

Protein sequence:

>221_residues
MATYLVTGANRGIGLEYCRQLQQRGDTVIAACRTSSPELEALGIQIETQVDITSDTAVADFKQRLAGQSLDGLINNAGMI
DRVTLEDLNIESIRRQYEVNAIGPLRLTHALLPNLPSGSKVILMTSRMGSIGDNTSGSSYGYRMSKVALCMAGKSLSHDL
KPKGIAVAILHPGLVQTRMTRFNAKGITPEQSVNGLLERIDQLTLDNTGTFWHANGEVLPW

Sequences:

>Translated_221_residues
MATYLVTGANRGIGLEYCRQLQQRGDTVIAACRTSSPELEALGIQIETQVDITSDTAVADFKQRLAGQSLDGLINNAGMI
DRVTLEDLNIESIRRQYEVNAIGPLRLTHALLPNLPSGSKVILMTSRMGSIGDNTSGSSYGYRMSKVALCMAGKSLSHDL
KPKGIAVAILHPGLVQTRMTRFNAKGITPEQSVNGLLERIDQLTLDNTGTFWHANGEVLPW
>Mature_220_residues
ATYLVTGANRGIGLEYCRQLQQRGDTVIAACRTSSPELEALGIQIETQVDITSDTAVADFKQRLAGQSLDGLINNAGMID
RVTLEDLNIESIRRQYEVNAIGPLRLTHALLPNLPSGSKVILMTSRMGSIGDNTSGSSYGYRMSKVALCMAGKSLSHDLK
PKGIAVAILHPGLVQTRMTRFNAKGITPEQSVNGLLERIDQLTLDNTGTFWHANGEVLPW

Specific function: Cell-cell signaling protein required for fruiting body morphogenesis. Necessary for cellular aggregation, for spore differentiation, and for gene expression that is initiated after 6 hour of starvation [H]

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Secreted [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To yeast YKL071W [H]

Homologues:

Organism=Homo sapiens, GI4557649, Length=212, Percent_Identity=26.8867924528302, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI19743808, Length=188, Percent_Identity=28.7234042553192, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI119392083, Length=192, Percent_Identity=32.8125, Blast_Score=67, Evalue=9e-12,
Organism=Homo sapiens, GI40548397, Length=187, Percent_Identity=30.4812834224599, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI214010158, Length=187, Percent_Identity=30.4812834224599, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI214010156, Length=187, Percent_Identity=30.4812834224599, Blast_Score=65, Evalue=4e-11,
Organism=Homo sapiens, GI22758144, Length=187, Percent_Identity=30.4812834224599, Blast_Score=65, Evalue=4e-11,
Organism=Escherichia coli, GI1786701, Length=185, Percent_Identity=33.5135135135135, Blast_Score=75, Evalue=2e-15,
Organism=Escherichia coli, GI1787335, Length=186, Percent_Identity=27.4193548387097, Blast_Score=60, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17558996, Length=255, Percent_Identity=30.5882352941176, Blast_Score=92, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17558994, Length=241, Percent_Identity=31.1203319502075, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17558990, Length=249, Percent_Identity=28.9156626506024, Blast_Score=84, Evalue=8e-17,
Organism=Caenorhabditis elegans, GI17558992, Length=241, Percent_Identity=34.0248962655602, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI193207563, Length=241, Percent_Identity=29.4605809128631, Blast_Score=80, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17558006, Length=204, Percent_Identity=30.3921568627451, Blast_Score=76, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17559962, Length=250, Percent_Identity=32, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17541382, Length=251, Percent_Identity=29.4820717131474, Blast_Score=74, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17559964, Length=247, Percent_Identity=30.7692307692308, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17542178, Length=239, Percent_Identity=28.8702928870293, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI72001658, Length=244, Percent_Identity=29.9180327868852, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6322779, Length=246, Percent_Identity=28.4552845528455, Blast_Score=82, Evalue=5e-17,
Organism=Drosophila melanogaster, GI24640547, Length=252, Percent_Identity=32.5396825396825, Blast_Score=94, Evalue=5e-20,
Organism=Drosophila melanogaster, GI24643142, Length=182, Percent_Identity=32.967032967033, Blast_Score=75, Evalue=3e-14,
Organism=Drosophila melanogaster, GI23397609, Length=202, Percent_Identity=34.6534653465347, Blast_Score=72, Evalue=2e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 23968; Mature: 23837

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATYLVTGANRGIGLEYCRQLQQRGDTVIAACRTSSPELEALGIQIETQVDITSDTAVAD
CCEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCCCCEEEEEEEEEEEEEECCCHHHHH
FKQRLAGQSLDGLINNAGMIDRVTLEDLNIESIRRQYEVNAIGPLRLTHALLPNLPSGSK
HHHHHCCCCHHHHHCCCCCEEEEEECCCCHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCE
VILMTSRMGSIGDNTSGSSYGYRMSKVALCMAGKSLSHDLKPKGIAVAILHPGLVQTRMT
EEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCHHHHHHH
RFNAKGITPEQSVNGLLERIDQLTLDNTGTFWHANGEVLPW
HHCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCC
>Mature Secondary Structure 
ATYLVTGANRGIGLEYCRQLQQRGDTVIAACRTSSPELEALGIQIETQVDITSDTAVAD
CEEEEECCCCCCCHHHHHHHHHCCCEEEEEECCCCCCEEEEEEEEEEEEEECCCHHHHH
FKQRLAGQSLDGLINNAGMIDRVTLEDLNIESIRRQYEVNAIGPLRLTHALLPNLPSGSK
HHHHHCCCCHHHHHCCCCCEEEEEECCCCHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCE
VILMTSRMGSIGDNTSGSSYGYRMSKVALCMAGKSLSHDLKPKGIAVAILHPGLVQTRMT
EEEEECCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCHHHHHHH
RFNAKGITPEQSVNGLLERIDQLTLDNTGTFWHANGEVLPW
HHCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2152896; 2107980; 2118510; 1372277 [H]