Click here to switch to the map view.

The map label for this gene is ftsX [H]

Identifier: 158335012

GI number: 158335012

Start: 1837631

End: 1838566

Strand: Direct

Name: ftsX [H]

Synonym: AM1_1850

Alternate gene names: 158335012

Gene position: 1837631-1838566 (Clockwise)

Preceding gene: 158335011

Following gene: 158335017

Centisome position: 28.26

GC content: 48.5

Gene sequence:

>936_bases
ATGCGTTCTCATCCGTTCCAAGTTCCTGAACAACTCAAGGTGGTAGCCACAAAACTCACCTATTTGTTACAAGAAACGGG
GCGAGGTCTCAAGCGAGGCGGCTGGATGAATTGGGCTGCAATTAGTACTGTGACCGTATTGCTGTTCCTCCTCGGCATCA
GCTTGCAAACCTCCTGGCAAGTGAGTGGATTACTCAATAATTTAGGATCTCGATTTGAAGTTGCAGTTTATCTAAAGCCA
GAGGCCACTGGCACCCAGCTCAAATCCTCCATTGCTCAATTTCCCGATGTCTCCAGTATTGAAGTGATTCCTAAAGATGA
GGCTTGGAAAGAATTGCTAGCGGACCTAGGCACCACGGATATAGCAGGTGCCACGGAAGGATTAGGGGAAAATCCCTTGG
TCGATGCCCTCAAAGTACAGGCCAATTCTGCAATAGCCGTCCCAAATCTGGCGAAAAAGATTGCGCGTTTACGCGGGGTA
GAAACGGTTCAATATTTGGACGAAGCCCTGAAAAATCTCACCCAGCTAAATCGAGGATTTAGTCAGATCAGTTTGGGAGT
CGTGGCATTGCTGACGTTGACAGCGATTGCAGTCATCACTACCACGATTCGACTGATTGTCGTGGCTCGGAATCAAGAAA
TTGAAGTCATGAAATTGGTCGGGGCAACTACAAGCTGGATCTATTTCCCTTTTGTGTTGCAAGGGATCACCTTTGGGCTA
GTGGGAGCTGTCATTGCCTGGATATTTCTGGTGGTCATCCGACAGCTGATGCGCACCGCCTTTGCGCAGCAACCTATTTT
TTTACAAACCTTGGGAGAAGGACTACAGCTGAGTCCGTGGCAAGTCGTCGTATTGCCTCTAATTCTGTTAGGGTTTGGCA
GTGTTGTCGGGATTATTGGAAGTCTATTTGCGGTTCGCCGCTTCGCCAGCAAGTAG

Upstream 100 bases:

>100_bases
TAACAACCCACGATATGGGACTGATACAAGCGGTGAAAGCGCCCGTTGCTCAGCTCGATCAGGGGCGTTTACAGGTGGTA
CCCGCAGAACAGGTAATCTA

Downstream 100 bases:

>100_bases
CGGCTTATCCCCCAAAGAGCCTCTGCCACCAGCCCTGCTTTTTGGCAGGCTGTGGGCGCTGGGCAAGTTCCTGGGTTAAA
CGCTGGTTTGTTGCCCGTAA

Product: permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 311; Mature: 311

Protein sequence:

>311_residues
MRSHPFQVPEQLKVVATKLTYLLQETGRGLKRGGWMNWAAISTVTVLLFLLGISLQTSWQVSGLLNNLGSRFEVAVYLKP
EATGTQLKSSIAQFPDVSSIEVIPKDEAWKELLADLGTTDIAGATEGLGENPLVDALKVQANSAIAVPNLAKKIARLRGV
ETVQYLDEALKNLTQLNRGFSQISLGVVALLTLTAIAVITTTIRLIVVARNQEIEVMKLVGATTSWIYFPFVLQGITFGL
VGAVIAWIFLVVIRQLMRTAFAQQPIFLQTLGEGLQLSPWQVVVLPLILLGFGSVVGIIGSLFAVRRFASK

Sequences:

>Translated_311_residues
MRSHPFQVPEQLKVVATKLTYLLQETGRGLKRGGWMNWAAISTVTVLLFLLGISLQTSWQVSGLLNNLGSRFEVAVYLKP
EATGTQLKSSIAQFPDVSSIEVIPKDEAWKELLADLGTTDIAGATEGLGENPLVDALKVQANSAIAVPNLAKKIARLRGV
ETVQYLDEALKNLTQLNRGFSQISLGVVALLTLTAIAVITTTIRLIVVARNQEIEVMKLVGATTSWIYFPFVLQGITFGL
VGAVIAWIFLVVIRQLMRTAFAQQPIFLQTLGEGLQLSPWQVVVLPLILLGFGSVVGIIGSLFAVRRFASK
>Mature_311_residues
MRSHPFQVPEQLKVVATKLTYLLQETGRGLKRGGWMNWAAISTVTVLLFLLGISLQTSWQVSGLLNNLGSRFEVAVYLKP
EATGTQLKSSIAQFPDVSSIEVIPKDEAWKELLADLGTTDIAGATEGLGENPLVDALKVQANSAIAVPNLAKKIARLRGV
ETVQYLDEALKNLTQLNRGFSQISLGVVALLTLTAIAVITTTIRLIVVARNQEIEVMKLVGATTSWIYFPFVLQGITFGL
VGAVIAWIFLVVIRQLMRTAFAQQPIFLQTLGEGLQLSPWQVVVLPLILLGFGSVVGIIGSLFAVRRFASK

Specific function: Part of the ABC transporter ftsEX involved in sporulation. May act as an importer, possibly at the top of a hierarchical cascade leading to the correct temporal initiation of sporulation. Acts upstream of the histidine kinases KinA, KinB and KInC, the Rap

COG id: COG2177

COG function: function code D; Cell division protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable). Note=Unlike the E.coli ortholog, localization is not restricted to division septa, nor is it dependent on ftsZ [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-4 integral membrane protein family. FtsX subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003838 [H]

Pfam domain/function: PF02687 FtsX [H]

EC number: NA

Molecular weight: Translated: 33810; Mature: 33810

Theoretical pI: Translated: 10.22; Mature: 10.22

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRSHPFQVPEQLKVVATKLTYLLQETGRGLKRGGWMNWAAISTVTVLLFLLGISLQTSWQ
CCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHH
VSGLLNNLGSRFEVAVYLKPEATGTQLKSSIAQFPDVSSIEVIPKDEAWKELLADLGTTD
HHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHCCCCC
IAGATEGLGENPLVDALKVQANSAIAVPNLAKKIARLRGVETVQYLDEALKNLTQLNRGF
CCCCCCCCCCCCHHHHHHHHCCCCEECHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCH
SQISLGVVALLTLTAIAVITTTIRLIVVARNQEIEVMKLVGATTSWIYFPFVLQGITFGL
HHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHH
VGAVIAWIFLVVIRQLMRTAFAQQPIFLQTLGEGLQLSPWQVVVLPLILLGFGSVVGIIG
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
SLFAVRRFASK
HHHHHHHHHCC
>Mature Secondary Structure
MRSHPFQVPEQLKVVATKLTYLLQETGRGLKRGGWMNWAAISTVTVLLFLLGISLQTSWQ
CCCCCCCCHHHHHHHHHHHHHHHHHHCCHHHCCCCCCHHHHHHHHHHHHHHHCCCCCHHH
VSGLLNNLGSRFEVAVYLKPEATGTQLKSSIAQFPDVSSIEVIPKDEAWKELLADLGTTD
HHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHHCCCCC
IAGATEGLGENPLVDALKVQANSAIAVPNLAKKIARLRGVETVQYLDEALKNLTQLNRGF
CCCCCCCCCCCCHHHHHHHHCCCCEECHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCH
SQISLGVVALLTLTAIAVITTTIRLIVVARNQEIEVMKLVGATTSWIYFPFVLQGITFGL
HHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHCCCHHHHHHHHHHHHHHHHH
VGAVIAWIFLVVIRQLMRTAFAQQPIFLQTLGEGLQLSPWQVVVLPLILLGFGSVVGIIG
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
SLFAVRRFASK
HHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]