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The map label for this gene is pheA [H]

Identifier: 158335001

GI number: 158335001

Start: 1828207

End: 1829091

Strand: Reverse

Name: pheA [H]

Synonym: AM1_1839

Alternate gene names: 158335001

Gene position: 1829091-1828207 (Counterclockwise)

Preceding gene: 158335003

Following gene: 158335000

Centisome position: 28.12

GC content: 50.4

Gene sequence:

>885_bases
ATGTCGCTTTCCATTGCCCACCTGGGGCCTGCAGGAACCTATGCAGAACAAGCTGCGATCGCATATGCGGATTGGTACGC
TAATCTTACGCAACAGCCGATCCCCATCCTCTGTCCCTGTCCCAGCATTGCCCAAGCGCTGCAATCGACCGCTGCTGGCG
ATACTAAACTTTCTGTTTCCCCAGTCGAGAACTCCATTGAAGGCAGTGTCTCCGTTACCTTAGATACCGTCTGGCAGCTG
GAAATGCTGCAAATTCGGCAAGCTTTAGTGTTATCCATTGAGCATGTCTTGATTGCCAAAGCGCAACAATTGCAGTCGAT
TCAAGCGGTCTATTCTCACCCGCAAGCCCTCGGACAATGCCAGACCTGGCTGAAACATAACTTACCCCAAGCGACCTTGG
TGCCTGCCAGCTCAACGACAGAGGCCCTTAATTATGTGGATGAGGACGGTTCAATTGCAGCGATCTCCTCAGAACGAGCG
GCTCAGCTGTACCAACTGCCGGTGATTCAGCGGTCCATCCAAGATCATCCCGATAACTGCACCCGATTTTGGATTGTGAG
CCAAAAAGAGACACCTTATCCCGTTACGGCTCCAGAGGGTAGCCCGGTATATACATCTTTAGCCTTTAGCTTGCCAGCAA
ATGTTCCCGGTGCGTTGTTGCAGCCCCTAAAGATTTTCAATGACCGACATATTAATCTCAGTCGGATTGAGTCTCGTCCC
AGCAAACGCTCCTTAGGAGAATATGTCTTTTTTGTGGATGCAGAGGCGGACTTAAATACCAGCTTTTTTCAATCTGCTTT
AGATGAGTTAACCTCTCACACTGAAGTGCTGAAAGTATTTGGCAGTTATCCCCTGGTGCAAGTGGTGGGGACCGTTGGGC
CATAG

Upstream 100 bases:

>100_bases
GTTAAGGTAATTTTACATTTCTTTGGCTGATTCGTGGGTAGATTCCTCAGATGAACTTTCACAAACCCAGATAAACTGTC
TGTAATGATCAGGGATGTTT

Downstream 100 bases:

>100_bases
AAGATACCATCAACTAGCCAATGAGTTTGGTGGTAAAACTGCACGCCAGTTGTGAAATAAACTGAAGCAGTACTCTTTCC
GGGGCATATTTTGGGATCTG

Product: prephenate dehydratase

Products: NA

Alternate protein names: Chorismate mutase; CM; Prephenate dehydratase; PDT [H]

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MSLSIAHLGPAGTYAEQAAIAYADWYANLTQQPIPILCPCPSIAQALQSTAAGDTKLSVSPVENSIEGSVSVTLDTVWQL
EMLQIRQALVLSIEHVLIAKAQQLQSIQAVYSHPQALGQCQTWLKHNLPQATLVPASSTTEALNYVDEDGSIAAISSERA
AQLYQLPVIQRSIQDHPDNCTRFWIVSQKETPYPVTAPEGSPVYTSLAFSLPANVPGALLQPLKIFNDRHINLSRIESRP
SKRSLGEYVFFVDAEADLNTSFFQSALDELTSHTEVLKVFGSYPLVQVVGTVGP

Sequences:

>Translated_294_residues
MSLSIAHLGPAGTYAEQAAIAYADWYANLTQQPIPILCPCPSIAQALQSTAAGDTKLSVSPVENSIEGSVSVTLDTVWQL
EMLQIRQALVLSIEHVLIAKAQQLQSIQAVYSHPQALGQCQTWLKHNLPQATLVPASSTTEALNYVDEDGSIAAISSERA
AQLYQLPVIQRSIQDHPDNCTRFWIVSQKETPYPVTAPEGSPVYTSLAFSLPANVPGALLQPLKIFNDRHINLSRIESRP
SKRSLGEYVFFVDAEADLNTSFFQSALDELTSHTEVLKVFGSYPLVQVVGTVGP
>Mature_293_residues
SLSIAHLGPAGTYAEQAAIAYADWYANLTQQPIPILCPCPSIAQALQSTAAGDTKLSVSPVENSIEGSVSVTLDTVWQLE
MLQIRQALVLSIEHVLIAKAQQLQSIQAVYSHPQALGQCQTWLKHNLPQATLVPASSTTEALNYVDEDGSIAAISSERAA
QLYQLPVIQRSIQDHPDNCTRFWIVSQKETPYPVTAPEGSPVYTSLAFSLPANVPGALLQPLKIFNDRHINLSRIESRPS
KRSLGEYVFFVDAEADLNTSFFQSALDELTSHTEVLKVFGSYPLVQVVGTVGP

Specific function: L-phenylalanine biosynthesis. [C]

COG id: COG0077

COG function: function code E; Prephenate dehydratase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 prephenate dehydratase domain [H]

Homologues:

Organism=Escherichia coli, GI1788951, Length=291, Percent_Identity=31.6151202749141, Blast_Score=125, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6324013, Length=330, Percent_Identity=26.3636363636364, Blast_Score=88, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002912
- InterPro:   IPR008242
- InterPro:   IPR002701
- InterPro:   IPR020822
- InterPro:   IPR010957
- InterPro:   IPR001086
- InterPro:   IPR018528 [H]

Pfam domain/function: PF01842 ACT; PF01817 CM_2; PF00800 PDT [H]

EC number: =5.4.99.5; =4.2.1.51 [H]

Molecular weight: Translated: 31956; Mature: 31825

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00857 PREPHENATE_DEHYDR_1 ; PS00858 PREPHENATE_DEHYDR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSIAHLGPAGTYAEQAAIAYADWYANLTQQPIPILCPCPSIAQALQSTAAGDTKLSVS
CCEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHCCCCCEEEEC
PVENSIEGSVSVTLDTVWQLEMLQIRQALVLSIEHVLIAKAQQLQSIQAVYSHPQALGQC
CCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
QTWLKHNLPQATLVPASSTTEALNYVDEDGSIAAISSERAAQLYQLPVIQRSIQDHPDNC
HHHHHHCCCCEEEECCCCHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCC
TRFWIVSQKETPYPVTAPEGSPVYTSLAFSLPANVPGALLQPLKIFNDRHINLSRIESRP
EEEEEEECCCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCCHHHHHCCC
SKRSLGEYVFFVDAEADLNTSFFQSALDELTSHTEVLKVFGSYPLVQVVGTVGP
CHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCC
>Mature Secondary Structure 
SLSIAHLGPAGTYAEQAAIAYADWYANLTQQPIPILCPCPSIAQALQSTAAGDTKLSVS
CEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEECCHHHHHHHHHHCCCCCEEEEC
PVENSIEGSVSVTLDTVWQLEMLQIRQALVLSIEHVLIAKAQQLQSIQAVYSHPQALGQC
CCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHH
QTWLKHNLPQATLVPASSTTEALNYVDEDGSIAAISSERAAQLYQLPVIQRSIQDHPDNC
HHHHHHCCCCEEEECCCCHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCC
TRFWIVSQKETPYPVTAPEGSPVYTSLAFSLPANVPGALLQPLKIFNDRHINLSRIESRP
EEEEEEECCCCCCCCCCCCCCCEEEEEEEECCCCCCHHHHHHHHHHCCCCCCHHHHHCCC
SKRSLGEYVFFVDAEADLNTSFFQSALDELTSHTEVLKVFGSYPLVQVVGTVGP
CHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9537320 [H]