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The map label for this gene is ftsW [H]

Identifier: 158334974

GI number: 158334974

Start: 1798887

End: 1800338

Strand: Reverse

Name: ftsW [H]

Synonym: AM1_1811

Alternate gene names: 158334974

Gene position: 1800338-1798887 (Counterclockwise)

Preceding gene: 158334975

Following gene: 158334973

Centisome position: 27.68

GC content: 47.59

Gene sequence:

>1452_bases
GTGAAGATACGTCGCCTCATTCCCTCCCTTCCCTATTCAACAGAAGAATGGGCTGCTGAAGCCCGATTCCTTCATTGGCT
AACCCTCTTTTGGTTAGGCATTGGCCTTGTCGTTCTATTCTCAGCGTCCTACCATGCGGGGGCGATTGAATCTGGGGATG
GTCTCTACTATTCCAAACGCCAGCTATTAGGGGTGATTTTGGGACTGTTGGGTTTTTGTGCGGTGATCCACATTCCCTTA
TACAAACTCATGAAAGTTTCCGCGTTTGGATTCTTTCTGTTTTTGATGTTGATTTTTGCCACAAAAATTCCAGGGCTAGG
GATCACGATTAATGGTGCAACCCGATGGATTGATATTGGCCCCTTTCCACTTCAGCCTTCCGAATTAATCAAACCTTTCC
TGATTCTGCAGAGTGCCTATATTTTTAATCGCTGGTCTCGATTAACCCTGGGTGAGCGACTATGGTGGTTATTTCTATTT
TCCCTCACCCTTTTGGGCATCTTGGTCCAGCCGAATCTAAGCACCACGGCCTTGTGTGGTATGACCCTTTGGTTGATTGC
TTTGGCAGCGGGGTTACGCTACCAGTCTCTTTTCTTAACGGCGTTGGCAGGGGTAGGTCTAGCAGCGATTAGTGTGTTGC
GTAATCCCTATCAGCAAAGTCGGATCCTCTCATTCTTGAATCCTTGGGCCGACGCCCTTGGAGATGGCTTTCAGCTTCAT
CAGAGCTTGTTAGCAGTTGGCTCCGGGGGCATCCTGGGCGTTGGCTTTGGTGAGTCACAATTGAAGCTTTCCTATTTACC
TATTCAGCATACAGATTTTATTTTTGCGGTTTTTGCCGAAGAATTTGGTTTGTTGGGGGGATTTTGTTTTTTATTGCTCC
TGGGGACCTACAGCTTTTTAGCCTTACGGGTAGCCATGAAATCTACCCATGTCATTCAGCGTTTGGTGGCCATTGGGGCC
ATGATTTTCTTAGTCGGTCAGGCCTTGATAAATATCGGTGTGGTAATTGGTGTATTGCCAACGACAGGTCTTCCCCTCCC
CATGTTTAGCTATGGGGGGAATTCTATGATCGCTAGCTTATTAATCGCAGGACTGTTGATCCGGGCTGCTCGAGAGAGCC
AAAGTGCCGAGGTGGTTGCTATCCCCCATCATGAGGGCGAGTCCCCATCTTTGATCCGACTGGTTGGCGATCACTCTTCC
GTGGCAACAGCTAGACATGGTTCTTCTGCCAATGCGCTATCTGGTCCTCAAACTTCTCTGCATCCTCGCGAAAATGAACA
CCTAAAGTTAGTCCGTAAACGGAAACCAACTTCTTTATGGCGCAGAATACTCGTTAAACTTCGCTCATCAAAGGGTGTAG
CGTCTGCAACCGCTAGAAAAAATGATCCTAAAGCAGCACTGGCTGCTAAAAAACAACGACTAAAACAACGCCGAAAACAC
AGACTTCGTTAA

Upstream 100 bases:

>100_bases
GATCACCAATCGCTGATGTGAGGGGTTGCTCATTAACCCCCTTCAATTCCTAGATGGGTCTGCTATACTGGCCTCGACTT
AACGCTGGGAATTACTGGTT

Downstream 100 bases:

>100_bases
GATCAATAGCGAACACCTGATTGTTAGTTGCGTCGAAGCAGCTTCTCCTTATGCTGGAAACGCTGGAAATTCAGCTTTAT
CACCTTGAACAATTTGCGAA

Product: cell cycle protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 483; Mature: 483

Protein sequence:

>483_residues
MKIRRLIPSLPYSTEEWAAEARFLHWLTLFWLGIGLVVLFSASYHAGAIESGDGLYYSKRQLLGVILGLLGFCAVIHIPL
YKLMKVSAFGFFLFLMLIFATKIPGLGITINGATRWIDIGPFPLQPSELIKPFLILQSAYIFNRWSRLTLGERLWWLFLF
SLTLLGILVQPNLSTTALCGMTLWLIALAAGLRYQSLFLTALAGVGLAAISVLRNPYQQSRILSFLNPWADALGDGFQLH
QSLLAVGSGGILGVGFGESQLKLSYLPIQHTDFIFAVFAEEFGLLGGFCFLLLLGTYSFLALRVAMKSTHVIQRLVAIGA
MIFLVGQALINIGVVIGVLPTTGLPLPMFSYGGNSMIASLLIAGLLIRAARESQSAEVVAIPHHEGESPSLIRLVGDHSS
VATARHGSSANALSGPQTSLHPRENEHLKLVRKRKPTSLWRRILVKLRSSKGVASATARKNDPKAALAAKKQRLKQRRKH
RLR

Sequences:

>Translated_483_residues
MKIRRLIPSLPYSTEEWAAEARFLHWLTLFWLGIGLVVLFSASYHAGAIESGDGLYYSKRQLLGVILGLLGFCAVIHIPL
YKLMKVSAFGFFLFLMLIFATKIPGLGITINGATRWIDIGPFPLQPSELIKPFLILQSAYIFNRWSRLTLGERLWWLFLF
SLTLLGILVQPNLSTTALCGMTLWLIALAAGLRYQSLFLTALAGVGLAAISVLRNPYQQSRILSFLNPWADALGDGFQLH
QSLLAVGSGGILGVGFGESQLKLSYLPIQHTDFIFAVFAEEFGLLGGFCFLLLLGTYSFLALRVAMKSTHVIQRLVAIGA
MIFLVGQALINIGVVIGVLPTTGLPLPMFSYGGNSMIASLLIAGLLIRAARESQSAEVVAIPHHEGESPSLIRLVGDHSS
VATARHGSSANALSGPQTSLHPRENEHLKLVRKRKPTSLWRRILVKLRSSKGVASATARKNDPKAALAAKKQRLKQRRKH
RLR
>Mature_483_residues
MKIRRLIPSLPYSTEEWAAEARFLHWLTLFWLGIGLVVLFSASYHAGAIESGDGLYYSKRQLLGVILGLLGFCAVIHIPL
YKLMKVSAFGFFLFLMLIFATKIPGLGITINGATRWIDIGPFPLQPSELIKPFLILQSAYIFNRWSRLTLGERLWWLFLF
SLTLLGILVQPNLSTTALCGMTLWLIALAAGLRYQSLFLTALAGVGLAAISVLRNPYQQSRILSFLNPWADALGDGFQLH
QSLLAVGSGGILGVGFGESQLKLSYLPIQHTDFIFAVFAEEFGLLGGFCFLLLLGTYSFLALRVAMKSTHVIQRLVAIGA
MIFLVGQALINIGVVIGVLPTTGLPLPMFSYGGNSMIASLLIAGLLIRAARESQSAEVVAIPHHEGESPSLIRLVGDHSS
VATARHGSSANALSGPQTSLHPRENEHLKLVRKRKPTSLWRRILVKLRSSKGVASATARKNDPKAALAAKKQRLKQRRKH
RLR

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=379, Percent_Identity=33.245382585752, Blast_Score=167, Evalue=1e-42,
Organism=Escherichia coli, GI1786853, Length=324, Percent_Identity=33.641975308642, Blast_Score=130, Evalue=1e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 53000; Mature: 53000

Theoretical pI: Translated: 10.98; Mature: 10.98

Prosite motif: PS00428 FTSW_RODA_SPOVE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIRRLIPSLPYSTEEWAAEARFLHWLTLFWLGIGLVVLFSASYHAGAIESGDGLYYSKR
CCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHH
QLLGVILGLLGFCAVIHIPLYKLMKVSAFGFFLFLMLIFATKIPGLGITINGATRWIDIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEECC
PFPLQPSELIKPFLILQSAYIFNRWSRLTLGERLWWLFLFSLTLLGILVQPNLSTTALCG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
MTLWLIALAAGLRYQSLFLTALAGVGLAAISVLRNPYQQSRILSFLNPWADALGDGFQLH
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCHHHHH
QSLLAVGSGGILGVGFGESQLKLSYLPIQHTDFIFAVFAEEFGLLGGFCFLLLLGTYSFL
HHHHHHCCCCEEEECCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALRVAMKSTHVIQRLVAIGAMIFLVGQALINIGVVIGVLPTTGLPLPMFSYGGNSMIASL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHH
LIAGLLIRAARESQSAEVVAIPHHEGESPSLIRLVGDHSSVATARHGSSANALSGPQTSL
HHHHHHHHHHHCCCCCCEEEECCCCCCCCCEEEEECCCCHHHHHCCCCCCCCCCCCCCCC
HPRENEHLKLVRKRKPTSLWRRILVKLRSSKGVASATARKNDPKAALAAKKQRLKQRRKH
CCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHH
RLR
CCC
>Mature Secondary Structure
MKIRRLIPSLPYSTEEWAAEARFLHWLTLFWLGIGLVVLFSASYHAGAIESGDGLYYSKR
CCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHH
QLLGVILGLLGFCAVIHIPLYKLMKVSAFGFFLFLMLIFATKIPGLGITINGATRWIDIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCEEEEECC
PFPLQPSELIKPFLILQSAYIFNRWSRLTLGERLWWLFLFSLTLLGILVQPNLSTTALCG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
MTLWLIALAAGLRYQSLFLTALAGVGLAAISVLRNPYQQSRILSFLNPWADALGDGFQLH
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCHHHHH
QSLLAVGSGGILGVGFGESQLKLSYLPIQHTDFIFAVFAEEFGLLGGFCFLLLLGTYSFL
HHHHHHCCCCEEEECCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALRVAMKSTHVIQRLVAIGAMIFLVGQALINIGVVIGVLPTTGLPLPMFSYGGNSMIASL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHCCCHHHHHHH
LIAGLLIRAARESQSAEVVAIPHHEGESPSLIRLVGDHSSVATARHGSSANALSGPQTSL
HHHHHHHHHHHCCCCCCEEEECCCCCCCCCEEEEECCCCHHHHHCCCCCCCCCCCCCCCC
HPRENEHLKLVRKRKPTSLWRRILVKLRSSKGVASATARKNDPKAALAAKKQRLKQRRKH
CCCCCHHHHHHHHCCCHHHHHHHHHHHHCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHHH
RLR
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]