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The map label for this gene is yycG [H]

Identifier: 158334899

GI number: 158334899

Start: 1722961

End: 1724928

Strand: Reverse

Name: yycG [H]

Synonym: AM1_1735

Alternate gene names: 158334899

Gene position: 1724928-1722961 (Counterclockwise)

Preceding gene: 158334901

Following gene: 158334897

Centisome position: 26.52

GC content: 48.63

Gene sequence:

>1968_bases
GTGAGTAATTTAGACTCTTTGTTGCAGACTCTGTTAACGGACTTACCAGATCTGCATCCACAGATGTATTTTAAGTCGTC
TCTCAATGCTCTCTGTCGGGCCATTGAAGATGTTGTGCTGGCGGGAAATGAAGCCCCCCTCGTCATTGCTAGTTTTCAAC
AGGAGCGCTTTTATCGCCAAGAAACCCGTCGATATCAGCGTATTGCTCAAAAGACAGACCATGTCTATGTTCTGGCAGCC
CCTGAACCGGAATCCAGTTTTGCGATCGCATCCGATCAATACGAAACCATTCCCCTCGATCTTGAGGATAGTCTGGCCAA
CGAAAAACATTTGATTATCGTGGGTCAAGACTACACGGCCTGCTTGGCCTGCCAAGAACAGAAGAAAGTACTCACGTCCG
TCGAACAGTCTCAACGGTACGAAGGCATTTGGACCTTTGAACGAGACGTGTGCCTGCATGCCGCCAGCCTTCTGTTGGAT
CGGATTGCCCAATATCGTCCTGAGCTGGCGTCTAAAGTCAAAAAGGCCAAGAAGCAATACTGTTTAACTTCGACTTCTTC
CATTCCCCCCTTGCCTGTCTTGCAATCTCGGGTGTTTGGCCAGCGATTGGTGACTTATTTACAGGCGAGTCAATACAAAT
TACTCAAAGCCTATCGAGCCCTATCGGCTAAAGAACGAAAAGAGCGGTTTGCCAATGCCATGACGGCTGCGATCCGCCAA
TCCCTTGACCCGAAAGAAGTGTTGGCGGTTGCCGTCAATGAGTTAGGTAAAGTATTCGAGCATTGTCGGTGTATTCTCTA
CTGTTGCGATCGCACCGATGAAGCCGTTGAAATTGAATATGAATTTGTGGCCCCAGGCTTGCCCTCCTTACAAGGAACCC
CCTGGCCCATTAGCACCAACCCTCTCTTATCTGTTGCTCTAGCCCAAGAACGGGCCATTGCCATTGCCGATGTCTTTGAA
GTTCAACACCTGCGCCAAGATAAAAAATTTGCAGCCAAGTTAGAACAATGGCAAATTCATTCCTGGTTGATTGCCCCGAT
TCGACATCAGGGAGAATTGTTGGGGGTCTTAGAGTTGCACCATGGTGGACCCCTGATTTATCAGTGGCATGAAAATGATA
TTGCCCTAGTCGAAGCCATTGCTGCCCAAGCCGGGGTTGCCCTCACCCAAGCTCAAGCCTATTCAGATTCTGAATCCCTT
AACCGCAACTTGGCTGCTCTCGAACAAACCCGGAGTAATTTGATTGCCATTGTTGGCCATGAACTGCGGACTCCCCTGTC
TACTATCCAGGTTTGTTTAGAAAGTTTGGATAGTGAACCGGATATTTCGCCAGTCTTTCGCCAAGCTCTCCTGAGCACGG
CCCTAGAAGACTTAGGTCGTTTGCGGGATTTGATTCAAGATATTCTAATTCTCTCTCGGTTAGAGGGGGGACAAATCTAT
AACCAAATTGAGTCCATTGAATTTCAAGAAACCCTAGAGCTGGCCTTGAGTTCCATGCGATCGAGCAATAACAGTAAAGA
TTTACCCACCATCAGTGTGGAGGTTGATCCGCATCTACCCACCATTCAGGTCGATGCGGAAGGCCTAGAAGAAGTGCTTA
ATCGGATTCTGGATAATGCTTGTAAGTTCACAGGGGTGGATGGAGAAGTGACCATTCAAGCTCATATTGCCCCAGACGAT
GACTGTTTGGAAGTCATTGTCGCCGATACTGGGAGAGGCATTGAGCCGAGCCGATTGGAATCTATCTTTGATTCTTTCTA
TCAAGAAGAAGACTTTCTGCGGCGTAGTAAAGGCGGTACGGGCTTGGGATTAGCCATTTGCCGACAAGTGATTCAAGGGA
TGAATGGCAGAATCTGGGCGGAATCTGCCGGACGCGATCAAGGCAGCGCATTTCATTTCACGCTGCCCTTAGAGGCGCCT
AGTGACTCCCAAGATCTAATGCCGGTTACCCAAACCAGTCACCCTTAG

Upstream 100 bases:

>100_bases
CGCCAAAACGAGCCTCAGTTCGCTTTTTTCTGCTGTTAACTTTCCCTACTAGTGTCAGGCCGTTGTCCCTAATCTAAGCA
AGATTCAGCAAGCTGTTGGT

Downstream 100 bases:

>100_bases
AGGGGCCGAGAATAACCCAAAGCATCCTTGACCTTCGTTAAGGTCTTGTTGGCAATCTCACTGGCTTGGTCTTTGCCCTG
TTGGAGAACCCCCTCCAAAT

Product: GAF sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 655; Mature: 654

Protein sequence:

>655_residues
MSNLDSLLQTLLTDLPDLHPQMYFKSSLNALCRAIEDVVLAGNEAPLVIASFQQERFYRQETRRYQRIAQKTDHVYVLAA
PEPESSFAIASDQYETIPLDLEDSLANEKHLIIVGQDYTACLACQEQKKVLTSVEQSQRYEGIWTFERDVCLHAASLLLD
RIAQYRPELASKVKKAKKQYCLTSTSSIPPLPVLQSRVFGQRLVTYLQASQYKLLKAYRALSAKERKERFANAMTAAIRQ
SLDPKEVLAVAVNELGKVFEHCRCILYCCDRTDEAVEIEYEFVAPGLPSLQGTPWPISTNPLLSVALAQERAIAIADVFE
VQHLRQDKKFAAKLEQWQIHSWLIAPIRHQGELLGVLELHHGGPLIYQWHENDIALVEAIAAQAGVALTQAQAYSDSESL
NRNLAALEQTRSNLIAIVGHELRTPLSTIQVCLESLDSEPDISPVFRQALLSTALEDLGRLRDLIQDILILSRLEGGQIY
NQIESIEFQETLELALSSMRSSNNSKDLPTISVEVDPHLPTIQVDAEGLEEVLNRILDNACKFTGVDGEVTIQAHIAPDD
DCLEVIVADTGRGIEPSRLESIFDSFYQEEDFLRRSKGGTGLGLAICRQVIQGMNGRIWAESAGRDQGSAFHFTLPLEAP
SDSQDLMPVTQTSHP

Sequences:

>Translated_655_residues
MSNLDSLLQTLLTDLPDLHPQMYFKSSLNALCRAIEDVVLAGNEAPLVIASFQQERFYRQETRRYQRIAQKTDHVYVLAA
PEPESSFAIASDQYETIPLDLEDSLANEKHLIIVGQDYTACLACQEQKKVLTSVEQSQRYEGIWTFERDVCLHAASLLLD
RIAQYRPELASKVKKAKKQYCLTSTSSIPPLPVLQSRVFGQRLVTYLQASQYKLLKAYRALSAKERKERFANAMTAAIRQ
SLDPKEVLAVAVNELGKVFEHCRCILYCCDRTDEAVEIEYEFVAPGLPSLQGTPWPISTNPLLSVALAQERAIAIADVFE
VQHLRQDKKFAAKLEQWQIHSWLIAPIRHQGELLGVLELHHGGPLIYQWHENDIALVEAIAAQAGVALTQAQAYSDSESL
NRNLAALEQTRSNLIAIVGHELRTPLSTIQVCLESLDSEPDISPVFRQALLSTALEDLGRLRDLIQDILILSRLEGGQIY
NQIESIEFQETLELALSSMRSSNNSKDLPTISVEVDPHLPTIQVDAEGLEEVLNRILDNACKFTGVDGEVTIQAHIAPDD
DCLEVIVADTGRGIEPSRLESIFDSFYQEEDFLRRSKGGTGLGLAICRQVIQGMNGRIWAESAGRDQGSAFHFTLPLEAP
SDSQDLMPVTQTSHP
>Mature_654_residues
SNLDSLLQTLLTDLPDLHPQMYFKSSLNALCRAIEDVVLAGNEAPLVIASFQQERFYRQETRRYQRIAQKTDHVYVLAAP
EPESSFAIASDQYETIPLDLEDSLANEKHLIIVGQDYTACLACQEQKKVLTSVEQSQRYEGIWTFERDVCLHAASLLLDR
IAQYRPELASKVKKAKKQYCLTSTSSIPPLPVLQSRVFGQRLVTYLQASQYKLLKAYRALSAKERKERFANAMTAAIRQS
LDPKEVLAVAVNELGKVFEHCRCILYCCDRTDEAVEIEYEFVAPGLPSLQGTPWPISTNPLLSVALAQERAIAIADVFEV
QHLRQDKKFAAKLEQWQIHSWLIAPIRHQGELLGVLELHHGGPLIYQWHENDIALVEAIAAQAGVALTQAQAYSDSESLN
RNLAALEQTRSNLIAIVGHELRTPLSTIQVCLESLDSEPDISPVFRQALLSTALEDLGRLRDLIQDILILSRLEGGQIYN
QIESIEFQETLELALSSMRSSNNSKDLPTISVEVDPHLPTIQVDAEGLEEVLNRILDNACKFTGVDGEVTIQAHIAPDDD
CLEVIVADTGRGIEPSRLESIFDSFYQEEDFLRRSKGGTGLGLAICRQVIQGMNGRIWAESAGRDQGSAFHFTLPLEAPS
DSQDLMPVTQTSHP

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786912, Length=243, Percent_Identity=32.0987654320988, Blast_Score=100, Evalue=5e-22,
Organism=Escherichia coli, GI1788393, Length=246, Percent_Identity=29.2682926829268, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI145693157, Length=233, Percent_Identity=34.3347639484979, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1786600, Length=230, Percent_Identity=28.2608695652174, Blast_Score=93, Evalue=6e-20,
Organism=Escherichia coli, GI1788713, Length=231, Percent_Identity=28.5714285714286, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1789149, Length=237, Percent_Identity=30.379746835443, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1787894, Length=286, Percent_Identity=27.6223776223776, Blast_Score=82, Evalue=1e-16,
Organism=Escherichia coli, GI48994928, Length=269, Percent_Identity=28.2527881040892, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1790346, Length=240, Percent_Identity=29.1666666666667, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI87081816, Length=300, Percent_Identity=29.3333333333333, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1788549, Length=245, Percent_Identity=29.3877551020408, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1786783, Length=232, Percent_Identity=25, Blast_Score=73, Evalue=5e-14,
Organism=Escherichia coli, GI1787374, Length=234, Percent_Identity=29.9145299145299, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1790436, Length=229, Percent_Identity=24.4541484716157, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1790861, Length=209, Percent_Identity=28.7081339712919, Blast_Score=65, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6322044, Length=81, Percent_Identity=48.1481481481481, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 73113; Mature: 72982

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNLDSLLQTLLTDLPDLHPQMYFKSSLNALCRAIEDVVLAGNEAPLVIASFQQERFYRQ
CCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHH
ETRRYQRIAQKTDHVYVLAAPEPESSFAIASDQYETIPLDLEDSLANEKHLIIVGQDYTA
HHHHHHHHHHCCCCEEEEECCCCCCCEEEECCCCCEECCCCHHHCCCCCEEEEECCCHHH
CLACQEQKKVLTSVEQSQRYEGIWTFERDVCLHAASLLLDRIAQYRPELASKVKKAKKQY
HHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
CLTSTSSIPPLPVLQSRVFGQRLVTYLQASQYKLLKAYRALSAKERKERFANAMTAAIRQ
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLDPKEVLAVAVNELGKVFEHCRCILYCCDRTDEAVEIEYEFVAPGLPSLQGTPWPISTN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCC
PLLSVALAQERAIAIADVFEVQHLRQDKKFAAKLEQWQIHSWLIAPIRHQGELLGVLELH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEE
HGGPLIYQWHENDIALVEAIAAQAGVALTQAQAYSDSESLNRNLAALEQTRSNLIAIVGH
CCCCEEEEEECCCHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHHHHHHHHCEEEEECH
ELRTPLSTIQVCLESLDSEPDISPVFRQALLSTALEDLGRLRDLIQDILILSRLEGGQIY
HHHCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
NQIESIEFQETLELALSSMRSSNNSKDLPTISVEVDPHLPTIQVDAEGLEEVLNRILDNA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEECHHHHHHHHHHHHHHH
CKFTGVDGEVTIQAHIAPDDDCLEVIVADTGRGIEPSRLESIFDSFYQEEDFLRRSKGGT
HCCCCCCCEEEEEEEECCCCHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
GLGLAICRQVIQGMNGRIWAESAGRDQGSAFHFTLPLEAPSDSQDLMPVTQTSHP
CHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SNLDSLLQTLLTDLPDLHPQMYFKSSLNALCRAIEDVVLAGNEAPLVIASFQQERFYRQ
CCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHHHHH
ETRRYQRIAQKTDHVYVLAAPEPESSFAIASDQYETIPLDLEDSLANEKHLIIVGQDYTA
HHHHHHHHHHCCCCEEEEECCCCCCCEEEECCCCCEECCCCHHHCCCCCEEEEECCCHHH
CLACQEQKKVLTSVEQSQRYEGIWTFERDVCLHAASLLLDRIAQYRPELASKVKKAKKQY
HHHHHHHHHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHH
CLTSTSSIPPLPVLQSRVFGQRLVTYLQASQYKLLKAYRALSAKERKERFANAMTAAIRQ
HHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLDPKEVLAVAVNELGKVFEHCRCILYCCDRTDEAVEIEYEFVAPGLPSLQGTPWPISTN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCC
PLLSVALAQERAIAIADVFEVQHLRQDKKFAAKLEQWQIHSWLIAPIRHQGELLGVLELH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEE
HGGPLIYQWHENDIALVEAIAAQAGVALTQAQAYSDSESLNRNLAALEQTRSNLIAIVGH
CCCCEEEEEECCCHHHHHHHHHHHCHHHHHHHHCCCHHHHHHHHHHHHHHHHCEEEEECH
ELRTPLSTIQVCLESLDSEPDISPVFRQALLSTALEDLGRLRDLIQDILILSRLEGGQIY
HHHCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
NQIESIEFQETLELALSSMRSSNNSKDLPTISVEVDPHLPTIQVDAEGLEEVLNRILDNA
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEECHHHHHHHHHHHHHHH
CKFTGVDGEVTIQAHIAPDDDCLEVIVADTGRGIEPSRLESIFDSFYQEEDFLRRSKGGT
HCCCCCCCEEEEEEEECCCCHHHEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCC
GLGLAICRQVIQGMNGRIWAESAGRDQGSAFHFTLPLEAPSDSQDLMPVTQTSHP
CHHHHHHHHHHHCCCCEEEECCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]