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The map label for this gene is trpS [H]

Identifier: 158334898

GI number: 158334898

Start: 1721954

End: 1722964

Strand: Direct

Name: trpS [H]

Synonym: AM1_1736

Alternate gene names: 158334898

Gene position: 1721954-1722964 (Clockwise)

Preceding gene: 158334896

Following gene: 158334900

Centisome position: 26.48

GC content: 48.47

Gene sequence:

>1011_bases
ATGGGTAAGCAACGTGTTCTTTCAGGTGTCCAACCCACTGGCACCCTTCACTTAGGTAATTACTTGGGAGCCATTCGGAA
TTGGGTCGAAGGACAGAGTAACTATGAAAACTATTTTTTTATTGCGGATCTCCATGCCATCACTGTTCCCCATGATCCTC
AACAACTAGCCGATAATACCTATTCCCTTGCTGCCCTGTATTTGGCCTGCGGCTTAGATCCTGAACACACTACAATCTTT
GTTCAGTCCCATATCTCTGCCCATGCAGAACTGGCCTGGCTATTTAACTGCATTACACCGCTTAATTGGCTCGAGCGCAT
GATCCAGTTCAAAGAGAAGGCCCTTAAGCAAGGAGAGAACGTCAGCATTGGCTTACTCGACTATCCCGTTTTACAAGCTG
CCGACATCCTGCTGTATCAAGCGGATCTAGTGCCCGTGGGAGAAGACCAAAAGCAGCATCTAGAGCTCACCAGAGATATT
GCAGCCCGTCTAAACTTTCAGTATGGAACCGAAGAGAATCCTATTCTCAAGGTGCCAGAGCCTCTTATTCGGCCAGAGGG
GGCCCGGATCATGAGCCTGACAGACGGCACTAATAAAATGTCAAAGTCAGATCCCTCGGAACAAAGTCGAATTACCTTAC
TAGACACTCCCGATCAAATTCGCAATAAAATTAAGCGCTGCAAAACTGATCCCGTCCGAGGACTGAGTTTTGATGATCCA
GACCGCCCAGAATGCCAAAATCTGCTGACCTTATATCAGTTAATGTCAGGGCAAGCTAAAACGGCAGTCGCAGAGGAATG
TGCAGAGATGGGCTGGGGACAGTTCAAGCCCCTGCTGACTGAGGTAATGATTGAGGGCCTGCGCCCCATCCAAGACCGCT
ATACAGCGTTAATGACGAATAAACAAGATTTGGAGGGGGTTCTCCAACAGGGCAAAGACCAAGCCAGTGAGATTGCCAAC
AAGACCTTAACGAAGGTCAAGGATGCTTTGGGTTATTCTCGGCCCCTCTAA

Upstream 100 bases:

>100_bases
TTGAGTTCTATAAAAACCTCAAGAGCGAGCAGACAGAAGCTATGTCACACTAGATCACTGTGCAGATTGCATTGTGATCA
ACGATTCAAACATTTAAAGC

Downstream 100 bases:

>100_bases
GGGTGACTGGTTTGGGTAACCGGCATTAGATCTTGGGAGTCACTAGGCGCCTCTAAGGGCAGCGTGAAATGAAATGCGCT
GCCTTGATCGCGTCCGGCAG

Product: tryptophanyl-tRNA synthetase

Products: NA

Alternate protein names: Tryptophan--tRNA ligase; TrpRS [H]

Number of amino acids: Translated: 336; Mature: 335

Protein sequence:

>336_residues
MGKQRVLSGVQPTGTLHLGNYLGAIRNWVEGQSNYENYFFIADLHAITVPHDPQQLADNTYSLAALYLACGLDPEHTTIF
VQSHISAHAELAWLFNCITPLNWLERMIQFKEKALKQGENVSIGLLDYPVLQAADILLYQADLVPVGEDQKQHLELTRDI
AARLNFQYGTEENPILKVPEPLIRPEGARIMSLTDGTNKMSKSDPSEQSRITLLDTPDQIRNKIKRCKTDPVRGLSFDDP
DRPECQNLLTLYQLMSGQAKTAVAEECAEMGWGQFKPLLTEVMIEGLRPIQDRYTALMTNKQDLEGVLQQGKDQASEIAN
KTLTKVKDALGYSRPL

Sequences:

>Translated_336_residues
MGKQRVLSGVQPTGTLHLGNYLGAIRNWVEGQSNYENYFFIADLHAITVPHDPQQLADNTYSLAALYLACGLDPEHTTIF
VQSHISAHAELAWLFNCITPLNWLERMIQFKEKALKQGENVSIGLLDYPVLQAADILLYQADLVPVGEDQKQHLELTRDI
AARLNFQYGTEENPILKVPEPLIRPEGARIMSLTDGTNKMSKSDPSEQSRITLLDTPDQIRNKIKRCKTDPVRGLSFDDP
DRPECQNLLTLYQLMSGQAKTAVAEECAEMGWGQFKPLLTEVMIEGLRPIQDRYTALMTNKQDLEGVLQQGKDQASEIAN
KTLTKVKDALGYSRPL
>Mature_335_residues
GKQRVLSGVQPTGTLHLGNYLGAIRNWVEGQSNYENYFFIADLHAITVPHDPQQLADNTYSLAALYLACGLDPEHTTIFV
QSHISAHAELAWLFNCITPLNWLERMIQFKEKALKQGENVSIGLLDYPVLQAADILLYQADLVPVGEDQKQHLELTRDIA
ARLNFQYGTEENPILKVPEPLIRPEGARIMSLTDGTNKMSKSDPSEQSRITLLDTPDQIRNKIKRCKTDPVRGLSFDDPD
RPECQNLLTLYQLMSGQAKTAVAEECAEMGWGQFKPLLTEVMIEGLRPIQDRYTALMTNKQDLEGVLQQGKDQASEIANK
TLTKVKDALGYSRPL

Specific function: Unknown

COG id: COG0180

COG function: function code J; Tryptophanyl-tRNA synthetase

Gene ontology:
GO:0000166: Tryptophanyl-tRNA synthetase
GO:0004812: Tryptophanyl-tRNA synthetase
GO:0004830: Tryptophanyl-tRNA synthetase
GO:0005524: Tryptophanyl-tRNA synthetase
GO:0005737: Tryptophanyl-tRNA synthetase
GO:0006412: Tryptophanyl-tRNA synthetase
GO:0006418: Tryptophanyl-tRNA synthetase
GO:0006436: Tryptophanyl-tRNA synthetase
GO:0016874: Tryptophanyl-tRNA synthetase

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI7710154, Length=332, Percent_Identity=39.7590361445783, Blast_Score=259, Evalue=2e-69,
Organism=Homo sapiens, GI41352700, Length=183, Percent_Identity=49.1803278688525, Blast_Score=187, Evalue=1e-47,
Organism=Escherichia coli, GI1789786, Length=336, Percent_Identity=46.1309523809524, Blast_Score=293, Evalue=1e-80,
Organism=Caenorhabditis elegans, GI71982800, Length=334, Percent_Identity=35.6287425149701, Blast_Score=196, Evalue=2e-50,
Organism=Caenorhabditis elegans, GI71982793, Length=334, Percent_Identity=35.6287425149701, Blast_Score=193, Evalue=9e-50,
Organism=Saccharomyces cerevisiae, GI6320474, Length=348, Percent_Identity=37.0689655172414, Blast_Score=211, Evalue=1e-55,
Organism=Drosophila melanogaster, GI24666151, Length=330, Percent_Identity=39.6969696969697, Blast_Score=251, Evalue=4e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR002305
- InterPro:   IPR014729
- InterPro:   IPR002306 [H]

Pfam domain/function: PF00579 tRNA-synt_1b [H]

EC number: =6.1.1.2 [H]

Molecular weight: Translated: 37707; Mature: 37576

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKQRVLSGVQPTGTLHLGNYLGAIRNWVEGQSNYENYFFIADLHAITVPHDPQQLADNT
CCHHHHHCCCCCCCEEEHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEECCCCHHHHHCCH
YSLAALYLACGLDPEHTTIFVQSHISAHAELAWLFNCITPLNWLERMIQFKEKALKQGEN
HHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCC
VSIGLLDYPVLQAADILLYQADLVPVGEDQKQHLELTRDIAARLNFQYGTEENPILKVPE
CEEEEECCHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEECCC
PLIRPEGARIMSLTDGTNKMSKSDPSEQSRITLLDTPDQIRNKIKRCKTDPVRGLSFDDP
HHHCCCCCEEEEECCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHCCCCCCCCCCCCCC
DRPECQNLLTLYQLMSGQAKTAVAEECAEMGWGQFKPLLTEVMIEGLRPIQDRYTALMTN
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCC
KQDLEGVLQQGKDQASEIANKTLTKVKDALGYSRPL
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
GKQRVLSGVQPTGTLHLGNYLGAIRNWVEGQSNYENYFFIADLHAITVPHDPQQLADNT
CHHHHHCCCCCCCEEEHHHHHHHHHHHHCCCCCCCCEEEEEEEEEEECCCCHHHHHCCH
YSLAALYLACGLDPEHTTIFVQSHISAHAELAWLFNCITPLNWLERMIQFKEKALKQGEN
HHHHHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHCCCC
VSIGLLDYPVLQAADILLYQADLVPVGEDQKQHLELTRDIAARLNFQYGTEENPILKVPE
CEEEEECCHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCEEECCC
PLIRPEGARIMSLTDGTNKMSKSDPSEQSRITLLDTPDQIRNKIKRCKTDPVRGLSFDDP
HHHCCCCCEEEEECCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHCCCCCCCCCCCCCC
DRPECQNLLTLYQLMSGQAKTAVAEECAEMGWGQFKPLLTEVMIEGLRPIQDRYTALMTN
CCHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCC
KQDLEGVLQQGKDQASEIANKTLTKVKDALGYSRPL
HHHHHHHHHHCHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12240834 [H]