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The map label for this gene is prmA [H]

Identifier: 158334454

GI number: 158334454

Start: 1265568

End: 1266506

Strand: Direct

Name: prmA [H]

Synonym: AM1_1275

Alternate gene names: 158334454

Gene position: 1265568-1266506 (Clockwise)

Preceding gene: 158334453

Following gene: 158334455

Centisome position: 19.46

GC content: 47.82

Gene sequence:

>939_bases
ATGGCCGATCCAGGCATCCACACTCCGTCGGACACTCCTACGGCTTTACCCCCTAGCCAATGGTGGGAAATTAAAGTTGT
GGGAGTGCCACTGCTAGATGATCTACTCTTCTGGCGGCTACAAGAAGAAGGATGCCAAGGCACGGCCAGCCAAATAGTCA
ATCAAGAGTTGACTGTTTGCGGATATTTATCCCTGGATCGGGTCCAGTCCATCGATCTGCAAAAACTTGCCGAGAGATTA
CATCAGGATGTCCAGTCAGTGGGATATCCTGCCCCAGATATTAGCTGGCAACTGATCACAGAAGAAGATTGGGCCCATAA
CTGGCGAGACTATTGGCATCCTCAAGAAGTTGGCAATCGGTTACTGATTTATCCGGCTTGGCTAGAGGTGCCAGAACAAT
GTGAACGTCTTTTGATTCGCCTTAATCCCGGAGTCGCTTTTGGCACAGGCGCTCATGCAACCACGCAGCTCTGCTTGCGA
GCCCTAGAACAACGAATTTCAGAACAACCCAATCCTCTAAGTATCGCTGATATTGGTTGTGGCACGGGTATTCTTTCCAT
TGCTGCTCTTCTTTTAGGAGTTCAAAAAGCCTATGCGGTTGATCTAGATCCACTCGCCATTGGTGCAACCCAAGCTAGTC
GAGAACTGAATGGCCTCACTTCAGATCAGTTATGGGTTAAGGAAGGAAGTCTTGATCAAGTGATACAGCAGCTTCAGCAT
CCAGTCCAAGGGTTTTGTTGCAATATTTTGGCCCATATCATTCTTGACCTAATACCCCATTTCGCTGATATCACTGACCA
AAACGGTTGGGGAATTCTTAGCGGCATTTTGGATACTCAAGAACCGATGATTATTGAGGCACTAAATGCTCATGGCTGGC
AAGTTCGCGATACCCATCATGAGCAAGACTGGTGCAGTTTAATCATTGAGCGCAGATGA

Upstream 100 bases:

>100_bases
TGATGGTTCTTAGCCTAGATGATCCCTTACCCGAAGGAGTACTGTCTGAAATCACGAATGTAGAAGGCATTCGTGATGCC
TATATTGTGAATTTACAATA

Downstream 100 bases:

>100_bases
AACACCGAACTCTCTAAATTCTGGCACTACCGATAGGTCGGATAAATCTGAAGTTTAGCTTCCCATTTATTTCAATCTAA
CTTTATAGATGCTTTTCCTG

Product: ribosomal protein L11 methyltransferase

Products: NA

Alternate protein names: L11 Mtase [H]

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MADPGIHTPSDTPTALPPSQWWEIKVVGVPLLDDLLFWRLQEEGCQGTASQIVNQELTVCGYLSLDRVQSIDLQKLAERL
HQDVQSVGYPAPDISWQLITEEDWAHNWRDYWHPQEVGNRLLIYPAWLEVPEQCERLLIRLNPGVAFGTGAHATTQLCLR
ALEQRISEQPNPLSIADIGCGTGILSIAALLLGVQKAYAVDLDPLAIGATQASRELNGLTSDQLWVKEGSLDQVIQQLQH
PVQGFCCNILAHIILDLIPHFADITDQNGWGILSGILDTQEPMIIEALNAHGWQVRDTHHEQDWCSLIIERR

Sequences:

>Translated_312_residues
MADPGIHTPSDTPTALPPSQWWEIKVVGVPLLDDLLFWRLQEEGCQGTASQIVNQELTVCGYLSLDRVQSIDLQKLAERL
HQDVQSVGYPAPDISWQLITEEDWAHNWRDYWHPQEVGNRLLIYPAWLEVPEQCERLLIRLNPGVAFGTGAHATTQLCLR
ALEQRISEQPNPLSIADIGCGTGILSIAALLLGVQKAYAVDLDPLAIGATQASRELNGLTSDQLWVKEGSLDQVIQQLQH
PVQGFCCNILAHIILDLIPHFADITDQNGWGILSGILDTQEPMIIEALNAHGWQVRDTHHEQDWCSLIIERR
>Mature_311_residues
ADPGIHTPSDTPTALPPSQWWEIKVVGVPLLDDLLFWRLQEEGCQGTASQIVNQELTVCGYLSLDRVQSIDLQKLAERLH
QDVQSVGYPAPDISWQLITEEDWAHNWRDYWHPQEVGNRLLIYPAWLEVPEQCERLLIRLNPGVAFGTGAHATTQLCLRA
LEQRISEQPNPLSIADIGCGTGILSIAALLLGVQKAYAVDLDPLAIGATQASRELNGLTSDQLWVKEGSLDQVIQQLQHP
VQGFCCNILAHIILDLIPHFADITDQNGWGILSGILDTQEPMIIEALNAHGWQVRDTHHEQDWCSLIIERR

Specific function: Methylates ribosomal protein L11 [H]

COG id: COG2264

COG function: function code J; Ribosomal protein L11 methylase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. PrmA family [H]

Homologues:

Organism=Escherichia coli, GI2367208, Length=126, Percent_Identity=45.2380952380952, Blast_Score=93, Evalue=2e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010456
- InterPro:   IPR004498 [H]

Pfam domain/function: PF06325 PrmA [H]

EC number: 2.1.1.- [C]

Molecular weight: Translated: 34881; Mature: 34750

Theoretical pI: Translated: 4.37; Mature: 4.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
0.3 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADPGIHTPSDTPTALPPSQWWEIKVVGVPLLDDLLFWRLQEEGCQGTASQIVNQELTVC
CCCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHE
GYLSLDRVQSIDLQKLAERLHQDVQSVGYPAPDISWQLITEEDWAHNWRDYWHPQEVGNR
EEHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCHHHCCHHHCCCHHHHCCE
LLIYPAWLEVPEQCERLLIRLNPGVAFGTGAHATTQLCLRALEQRISEQPNPLSIADIGC
EEEEEHHHCCHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCC
GTGILSIAALLLGVQKAYAVDLDPLAIGATQASRELNGLTSDQLWVKEGSLDQVIQQLQH
CHHHHHHHHHHHHHHHHHEECCCCCEECCHHHHHHHCCCCCCCEEEECCCHHHHHHHHHH
PVQGFCCNILAHIILDLIPHFADITDQNGWGILSGILDTQEPMIIEALNAHGWQVRDTHH
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCEEEECCCCCCEECCCCC
EQDWCSLIIERR
HHHHHHHHHCCC
>Mature Secondary Structure 
ADPGIHTPSDTPTALPPSQWWEIKVVGVPLLDDLLFWRLQEEGCQGTASQIVNQELTVC
CCCCCCCCCCCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHE
GYLSLDRVQSIDLQKLAERLHQDVQSVGYPAPDISWQLITEEDWAHNWRDYWHPQEVGNR
EEHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCEEEEECCHHHCCHHHCCCHHHHCCE
LLIYPAWLEVPEQCERLLIRLNPGVAFGTGAHATTQLCLRALEQRISEQPNPLSIADIGC
EEEEEHHHCCHHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHHHHHCCCCCCEEEECCC
GTGILSIAALLLGVQKAYAVDLDPLAIGATQASRELNGLTSDQLWVKEGSLDQVIQQLQH
CHHHHHHHHHHHHHHHHHEECCCCCEECCHHHHHHHCCCCCCCEEEECCCHHHHHHHHHH
PVQGFCCNILAHIILDLIPHFADITDQNGWGILSGILDTQEPMIIEALNAHGWQVRDTHH
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCEEEECCCCCCEECCCCC
EQDWCSLIIERR
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: Catalyzes the methylation of ribosomal protein L11 by S-adenosyl methionine [C]

General reaction: Transferases; Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA