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The map label for this gene is argJ [H]

Identifier: 158334275

GI number: 158334275

Start: 1068938

End: 1070155

Strand: Direct

Name: argJ [H]

Synonym: AM1_1094

Alternate gene names: 158334275

Gene position: 1068938-1070155 (Clockwise)

Preceding gene: 158334272

Following gene: 158334276

Centisome position: 16.44

GC content: 53.61

Gene sequence:

>1218_bases
ATGGCAGATTGGCAGACCATTCCAGGCGGGGTGACCGCTCCCCAGGGATACCGCGCAGCAGGTATGGCAACAGGCTTAAA
GCCATCAGGGGCAAAAGATTTGGCTCTGATTGTGTCCGATGTCAAAGCCCATGGAGCTGGGGTCTTTACGACCAATCGGG
TCAAAGCTGCTTGTGTGACCTATAGCCAGGACCGGATCCAAACCGGTCCAACCGAGATTCAGGCAATTTTGTGCAATTCT
GGCCAGGCAAATGCGGGAACAGGCCCCCAGGGAGACGCCATTGCGATCGCACAAGCAAAGAGCGCGGCCCAAACCTTGGG
ACTGACTCCGGAAGCCATTCTGATTGCTTCGACTGGGGTAATTGGTGAACAAATCCCGATTGATAAGGTGGAGGCGGCGA
TGCCTCAACTGGTGGGGCAGCTTTCCACTGAAGGGTCTGATCAAGCCGCCCAGGCGATTATGACCACTGACTTAGTGCCA
AAAACCATTGCTTTGGAAACTCACATTGGTGGGCAGCCAGTTCGAGTAGGGGGTATCGCCAAAGGTTCTGGCATGATTCA
TCCTGACATGGCGACCTTGTTAGTGTTTGTCACCTGTGATGCTCAGGTGGAACCGACGTTATGGCAGCTAATGATTGGGC
GAGCTGCAGATCGCAGTTTTAATCAAGTCACGGTGGATGGAGATACCAGTACCAACGATATGCTGTTAGCCCTAGCGAAT
GGCCAATCTGCCGCTCCAGCCATTCAGGGTCCCAGCCCTGAAGCCGAGCAAGTGGAAGCTCTGGTGACGGAAGTTTGTAA
GCAGTTGGCACAAAAAATTGCCCGAGATGGAGAAGGGGCGACTTGTCTAATTGAAGTGCAAGTCCAGGGGGCAACTGATG
AAGCGAGCGCCCAAAAGATTGCCAAAACCATTGCCGGGTCGATGTTAGTGAAATCGGCGGTGTTTGGCCGTGACCCCAAT
TGGGGCCGAATCGCGATGGCGGCAGGTCGGGCAGGGGTAGATTTTGATGCGACCCAGCTCCATATTCAGTTGGGGGATTT
CGTCCTGATGCATCATGGCACTCCCCAAGCGTTTGATCGAGAGGCGGCTAGCCAATATCTCCATCAAGATCCGGTGATGA
TTCAGGTTAGCGTCGGTGATGGAGCTGGGATGGGCAAAGCTTGGGGCTGTGATTTGAGCTATGACTACGTCAAAATCAAT
GCTGAATATACGACCTAA

Upstream 100 bases:

>100_bases
GCTGGCTTGAAACCCACCCTTGATGCCCATTAAAATAGGGCGACGCAGGCCCGTTGACGATGCTTGCTGATGCAGTACCT
AATGGGGGTAAGGAAAAGTA

Downstream 100 bases:

>100_bases
AGCTTTAATGGAATGTTGAATACCTAAAGGACTGGCCGTTTTGTATTACACATACTACGATTAAGCTCTGCTCATTTTCG
TAGATGATGGGTAGCCATAC

Product: bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein

Products: NA

Alternate protein names: Glutamate N-acetyltransferase; Ornithine acetyltransferase; OATase; Ornithine transacetylase; Amino-acid acetyltransferase; N-acetylglutamate synthase; AGS [H]

Number of amino acids: Translated: 405; Mature: 404

Protein sequence:

>405_residues
MADWQTIPGGVTAPQGYRAAGMATGLKPSGAKDLALIVSDVKAHGAGVFTTNRVKAACVTYSQDRIQTGPTEIQAILCNS
GQANAGTGPQGDAIAIAQAKSAAQTLGLTPEAILIASTGVIGEQIPIDKVEAAMPQLVGQLSTEGSDQAAQAIMTTDLVP
KTIALETHIGGQPVRVGGIAKGSGMIHPDMATLLVFVTCDAQVEPTLWQLMIGRAADRSFNQVTVDGDTSTNDMLLALAN
GQSAAPAIQGPSPEAEQVEALVTEVCKQLAQKIARDGEGATCLIEVQVQGATDEASAQKIAKTIAGSMLVKSAVFGRDPN
WGRIAMAAGRAGVDFDATQLHIQLGDFVLMHHGTPQAFDREAASQYLHQDPVMIQVSVGDGAGMGKAWGCDLSYDYVKIN
AEYTT

Sequences:

>Translated_405_residues
MADWQTIPGGVTAPQGYRAAGMATGLKPSGAKDLALIVSDVKAHGAGVFTTNRVKAACVTYSQDRIQTGPTEIQAILCNS
GQANAGTGPQGDAIAIAQAKSAAQTLGLTPEAILIASTGVIGEQIPIDKVEAAMPQLVGQLSTEGSDQAAQAIMTTDLVP
KTIALETHIGGQPVRVGGIAKGSGMIHPDMATLLVFVTCDAQVEPTLWQLMIGRAADRSFNQVTVDGDTSTNDMLLALAN
GQSAAPAIQGPSPEAEQVEALVTEVCKQLAQKIARDGEGATCLIEVQVQGATDEASAQKIAKTIAGSMLVKSAVFGRDPN
WGRIAMAAGRAGVDFDATQLHIQLGDFVLMHHGTPQAFDREAASQYLHQDPVMIQVSVGDGAGMGKAWGCDLSYDYVKIN
AEYTT
>Mature_404_residues
ADWQTIPGGVTAPQGYRAAGMATGLKPSGAKDLALIVSDVKAHGAGVFTTNRVKAACVTYSQDRIQTGPTEIQAILCNSG
QANAGTGPQGDAIAIAQAKSAAQTLGLTPEAILIASTGVIGEQIPIDKVEAAMPQLVGQLSTEGSDQAAQAIMTTDLVPK
TIALETHIGGQPVRVGGIAKGSGMIHPDMATLLVFVTCDAQVEPTLWQLMIGRAADRSFNQVTVDGDTSTNDMLLALANG
QSAAPAIQGPSPEAEQVEALVTEVCKQLAQKIARDGEGATCLIEVQVQGATDEASAQKIAKTIAGSMLVKSAVFGRDPNW
GRIAMAAGRAGVDFDATQLHIQLGDFVLMHHGTPQAFDREAASQYLHQDPVMIQVSVGDGAGMGKAWGCDLSYDYVKINA
EYTT

Specific function: Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis:the synthesis of acetylglutamate from glutamate and acetyl-CoA, and of ornithine by transacetylation between acetylornithine and glutamate [H]

COG id: COG1364

COG function: function code E; N-acetylglutamate synthase (N-acetylornithine aminotransferase)

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ArgJ family [H]

Homologues:

Organism=Saccharomyces cerevisiae, GI6323707, Length=420, Percent_Identity=36.6666666666667, Blast_Score=248, Evalue=2e-66,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002813
- InterPro:   IPR016117 [H]

Pfam domain/function: PF01960 ArgJ [H]

EC number: =2.3.1.35; =2.3.1.1 [H]

Molecular weight: Translated: 41993; Mature: 41862

Theoretical pI: Translated: 4.60; Mature: 4.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADWQTIPGGVTAPQGYRAAGMATGLKPSGAKDLALIVSDVKAHGAGVFTTNRVKAACVT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHEEEEEHHHHCCCCEEEECCEEEEEEE
YSQDRIQTGPTEIQAILCNSGQANAGTGPQGDAIAIAQAKSAAQTLGLTPEAILIASTGV
ECHHHCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEEHHHHHHHHCCCCCEEEEEECCC
IGEQIPIDKVEAAMPQLVGQLSTEGSDQAAQAIMTTDLVPKTIALETHIGGQPVRVGGIA
CCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCEEECCEE
KGSGMIHPDMATLLVFVTCDAQVEPTLWQLMIGRAADRSFNQVTVDGDTSTNDMLLALAN
CCCCCCCCCHHHEEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEEEEC
GQSAAPAIQGPSPEAEQVEALVTEVCKQLAQKIARDGEGATCLIEVQVQGATDEASAQKI
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCHHHHHHH
AKTIAGSMLVKSAVFGRDPNWGRIAMAAGRAGVDFDATQLHIQLGDFVLMHHGTPQAFDR
HHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCEEEEEEECCEEEEECCCCHHHHH
EAASQYLHQDPVMIQVSVGDGAGMGKAWGCDLSYDYVKINAEYTT
HHHHHHHCCCCEEEEEECCCCCCCCCEECCCCEEEEEEEEEEECC
>Mature Secondary Structure 
ADWQTIPGGVTAPQGYRAAGMATGLKPSGAKDLALIVSDVKAHGAGVFTTNRVKAACVT
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHEEEEEHHHHCCCCEEEECCEEEEEEE
YSQDRIQTGPTEIQAILCNSGQANAGTGPQGDAIAIAQAKSAAQTLGLTPEAILIASTGV
ECHHHCCCCCCCEEEEEECCCCCCCCCCCCCCEEEEEEHHHHHHHHCCCCCEEEEEECCC
IGEQIPIDKVEAAMPQLVGQLSTEGSDQAAQAIMTTDLVPKTIALETHIGGQPVRVGGIA
CCCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCEEECCEE
KGSGMIHPDMATLLVFVTCDAQVEPTLWQLMIGRAADRSFNQVTVDGDTSTNDMLLALAN
CCCCCCCCCHHHEEEEEEECCCCCHHHHHHHHHHHCCCCCCEEEECCCCCCCCEEEEEEC
GQSAAPAIQGPSPEAEQVEALVTEVCKQLAQKIARDGEGATCLIEVQVQGATDEASAQKI
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEEECCCCHHHHHHH
AKTIAGSMLVKSAVFGRDPNWGRIAMAAGRAGVDFDATQLHIQLGDFVLMHHGTPQAFDR
HHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCCEEEEEEECCEEEEECCCCHHHHH
EAASQYLHQDPVMIQVSVGDGAGMGKAWGCDLSYDYVKINAEYTT
HHHHHHHCCCCEEEEEECCCCCCCCCEECCCCEEEEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]