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The map label for this gene is aapM [H]

Identifier: 158334197

GI number: 158334197

Start: 983293

End: 984486

Strand: Direct

Name: aapM [H]

Synonym: AM1_1015

Alternate gene names: 158334197

Gene position: 983293-984486 (Clockwise)

Preceding gene: 158334196

Following gene: 158334198

Centisome position: 15.12

GC content: 49.58

Gene sequence:

>1194_bases
ATGCCGCCGAAATCTCCGACTCCCCTTTCAACATCCTCCCTATTGATCTGGCTGCGCCGCAACCTCTTCAGCACCTGGTA
CAACGGTTTGCTGACAGTGATTAGCCTCTGGATTATTTATCTAGGGGGACGAGGTCTATTTCGATGGATGTTTAGTCAGG
CCCAATGGACGGTTTTGCAAGCGAACTTGCGCTTGTTCTTTGTAGGCCGTTTTCCCATCGACCAAATTTGGCGAGTATGG
CTAATTTTAGTGCTGGTTTCTGCCGTCACGAGTTTGACCATTGGAGTCGTTCAATGGAACCGTATTTTACCCATCAGTAT
GGGCCTTTTGACGGCAATTAGTTTAGGCATTGTCCCTCTAGTTGGCGGGCAAGGTCCAGAACTTGTGTGGGTTGCAGCGA
TAGGAAGTGTTGCAGTACTCAATCTGCTAGGGGGACCGTGGTTAAAAACTCACCTGTCTCCTCGCTTGCTCAGCAGAGGT
TTGCCCGCTGTCTGGTTCCTGACCGCATTTATCATCTTGTGGCTATTAATGGGAGGGTTGGGAATCAGCACCATCGGTAC
TAATGTTTGGCAAGGGTTCTTATTGACGGTGGTAGCGGCGGTCGTGAGTATTGCCCTGTCCTTTCCCCTGGGGGTGTTGT
TGGCCTTAGGACGGCGCAGTCCCTTGCCCGTCATTCGGACCCTGAGCGTTCTCTACATTGAGGTCATTCGAGGGTTGCCC
TTGATTGGTGTTCTTTTTGTCGCTGGGGTGATGTTGCCATTGATATTGCCGAGCCAAGTGCAGCTAGATGCCGTCTTTCG
GGCAATTTGTGGCCTCACACTCTTTAGCGCGGCTTATCTGGCCGAAAATGTGCGTGGAGGATTACAGTCTATCCCCCAAG
GTCAATTTGAAGCTGCAAAGGCATTGGGGCTAAATCCCATGTTGGTTTTAGGATTAGTGGTGTTACCTCAAGCCCTGCGA
TCGGTGATTCCCGCGATAGTAGGTCAGTTTATCGGATTGTTCAAAGACACTTCACTACTATCAATTATTGGTCTCGTGGA
ACTGACGGGGGTTTCTCGATCTGTTCTATCCCAACCCCGATTTATTGGTCGGCATGGAGAAGTGTATTTGTTTATTGGTT
TGCTGTACTGGTTATTCTGTTATCTGATGTCTTTGGGGAGTCGGCGTTTAGAACATCAACTCGGTGTGAAGTGA

Upstream 100 bases:

>100_bases
TTAATGGCGATCTATTTGACGATGAGTTTACTCATTTCAATTCTGATGAATCTCTACAACCGCAGTATTCAATTGGTTGA
GCGATAGGGAAATAAGTCTA

Downstream 100 bases:

>100_bases
AGCTTGCTGTGTCCCAACCTGTAAATGAACTGTAATGACTGAAACGAACCCAATTATTGTGGCCACAGATGTTCACAAGT
GGTACGACTCCTTCCACGTC

Product: polar amino acid ABC transporter permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 397; Mature: 396

Protein sequence:

>397_residues
MPPKSPTPLSTSSLLIWLRRNLFSTWYNGLLTVISLWIIYLGGRGLFRWMFSQAQWTVLQANLRLFFVGRFPIDQIWRVW
LILVLVSAVTSLTIGVVQWNRILPISMGLLTAISLGIVPLVGGQGPELVWVAAIGSVAVLNLLGGPWLKTHLSPRLLSRG
LPAVWFLTAFIILWLLMGGLGISTIGTNVWQGFLLTVVAAVVSIALSFPLGVLLALGRRSPLPVIRTLSVLYIEVIRGLP
LIGVLFVAGVMLPLILPSQVQLDAVFRAICGLTLFSAAYLAENVRGGLQSIPQGQFEAAKALGLNPMLVLGLVVLPQALR
SVIPAIVGQFIGLFKDTSLLSIIGLVELTGVSRSVLSQPRFIGRHGEVYLFIGLLYWLFCYLMSLGSRRLEHQLGVK

Sequences:

>Translated_397_residues
MPPKSPTPLSTSSLLIWLRRNLFSTWYNGLLTVISLWIIYLGGRGLFRWMFSQAQWTVLQANLRLFFVGRFPIDQIWRVW
LILVLVSAVTSLTIGVVQWNRILPISMGLLTAISLGIVPLVGGQGPELVWVAAIGSVAVLNLLGGPWLKTHLSPRLLSRG
LPAVWFLTAFIILWLLMGGLGISTIGTNVWQGFLLTVVAAVVSIALSFPLGVLLALGRRSPLPVIRTLSVLYIEVIRGLP
LIGVLFVAGVMLPLILPSQVQLDAVFRAICGLTLFSAAYLAENVRGGLQSIPQGQFEAAKALGLNPMLVLGLVVLPQALR
SVIPAIVGQFIGLFKDTSLLSIIGLVELTGVSRSVLSQPRFIGRHGEVYLFIGLLYWLFCYLMSLGSRRLEHQLGVK
>Mature_396_residues
PPKSPTPLSTSSLLIWLRRNLFSTWYNGLLTVISLWIIYLGGRGLFRWMFSQAQWTVLQANLRLFFVGRFPIDQIWRVWL
ILVLVSAVTSLTIGVVQWNRILPISMGLLTAISLGIVPLVGGQGPELVWVAAIGSVAVLNLLGGPWLKTHLSPRLLSRGL
PAVWFLTAFIILWLLMGGLGISTIGTNVWQGFLLTVVAAVVSIALSFPLGVLLALGRRSPLPVIRTLSVLYIEVIRGLPL
IGVLFVAGVMLPLILPSQVQLDAVFRAICGLTLFSAAYLAENVRGGLQSIPQGQFEAAKALGLNPMLVLGLVVLPQALRS
VIPAIVGQFIGLFKDTSLLSIIGLVELTGVSRSVLSQPRFIGRHGEVYLFIGLLYWLFCYLMSLGSRRLEHQLGVK

Specific function: Part of a binding-protein-dependent transport system for L-amino acids, affects the uptake as well as efflux of these amino acids. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI87082239, Length=409, Percent_Identity=35.9413202933985, Blast_Score=225, Evalue=5e-60,
Organism=Escherichia coli, GI1788226, Length=189, Percent_Identity=38.0952380952381, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1786874, Length=179, Percent_Identity=30.1675977653631, Blast_Score=91, Evalue=9e-20,
Organism=Escherichia coli, GI1786873, Length=200, Percent_Identity=30, Blast_Score=89, Evalue=6e-19,
Organism=Escherichia coli, GI1787030, Length=206, Percent_Identity=29.6116504854369, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI48994930, Length=125, Percent_Identity=36, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI1788645, Length=162, Percent_Identity=29.6296296296296, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1787087, Length=132, Percent_Identity=31.0606060606061, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 43357; Mature: 43226

Theoretical pI: Translated: 11.66; Mature: 11.66

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
PPKSPTPLSTSSLLIWLRRNLFSTWYNGLLTVISLWIIYLGGRGLFRWMFSQAQWTVLQ
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHEEE
ANLRLFFVGRFPIDQIWRVWLILVLVSAVTSLTIGVVQWNRILPISMGLLTAISLGIVPL
ECEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC
VGGQGPELVWVAAIGSVAVLNLLGGPWLKTHLSPRLLSRGLPAVWFLTAFIILWLLMGGL
CCCCCCCEEEHHHHHHHHHHHHHCCCHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHCCC
GISTIGTNVWQGFLLTVVAAVVSIALSFPLGVLLALGRRSPLPVIRTLSVLYIEVIRGLP
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCH
LIGVLFVAGVMLPLILPSQVQLDAVFRAICGLTLFSAAYLAENVRGGLQSIPQGQFEAAK
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ALGLNPMLVLGLVVLPQALRSVIPAIVGQFIGLFKDTSLLSIIGLVELTGVSRSVLSQPR
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHCCCC
FIGRHGEVYLFIGLLYWLFCYLMSLGSRRLEHQLGVK
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8898392 [H]