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The map label for this gene is tadA [H]

Identifier: 158334188

GI number: 158334188

Start: 975361

End: 975858

Strand: Reverse

Name: tadA [H]

Synonym: AM1_1004

Alternate gene names: 158334188

Gene position: 975858-975361 (Counterclockwise)

Preceding gene: 158334190

Following gene: 158334184

Centisome position: 15.0

GC content: 53.21

Gene sequence:

>498_bases
GTGGACGTCCCCAGCTACCCTGAACATCAACAATGGATGGAAAAAGCGATTGCTTTAGCGACTCAAGCAGGTGCTGCAGG
AGAGGTGCCGGTAGGTGCAGTGATTATTGGCCCTGATGGAGACTGCATTGCTGAAGGAGAAAACAGACGAGAACGCGATC
ACGACCCGACTGCTCATGCAGAAATTGTAGCTCTCAGAGCTGCTAGCCAAGTTATACAGTCTTGGCGACTCCATGAATGT
CGTCTCTACGTCACCCTCGAACCCTGTCCCATGTGTGCAGGGGCAATTATCCAAGCTCGTCTTGGTCTGTTGGTCTATGG
CGCCCATGATCCGAAAACTGGAGCGATTCGAACCGTCCTCAATCTACCGGGTAGCCCTTGCTCCTTCCATAAACTCCCCG
TCATTGCAGGCGTCCTTGAGCCCACCTGTCGTCAGCAACTACAAGAGTGGTTTGCCCGCAGGCGACTACAGCAAAAAACT
CAGCCCTCATCCTCTTGA

Upstream 100 bases:

>100_bases
CTTCCACAACAGGCTGTTCAGGAGCATTGATCGAAGATTGCACTTTAATGAGAGGCATAATAGTCGGCTAGCATGTAACG
ATAGTTTTATTAAATCAAGA

Downstream 100 bases:

>100_bases
GACCAATTCCTACCTTGGATTGATCTGCTATAAACGCTCTTGAATAGAACGAATCAAGTGATTGACGTCTTTAATTTGGT
TTAATTCAACGGTATCTATA

Product: cytidine/deoxycytidylate deaminase region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 165; Mature: 165

Protein sequence:

>165_residues
MDVPSYPEHQQWMEKAIALATQAGAAGEVPVGAVIIGPDGDCIAEGENRRERDHDPTAHAEIVALRAASQVIQSWRLHEC
RLYVTLEPCPMCAGAIIQARLGLLVYGAHDPKTGAIRTVLNLPGSPCSFHKLPVIAGVLEPTCRQQLQEWFARRRLQQKT
QPSSS

Sequences:

>Translated_165_residues
MDVPSYPEHQQWMEKAIALATQAGAAGEVPVGAVIIGPDGDCIAEGENRRERDHDPTAHAEIVALRAASQVIQSWRLHEC
RLYVTLEPCPMCAGAIIQARLGLLVYGAHDPKTGAIRTVLNLPGSPCSFHKLPVIAGVLEPTCRQQLQEWFARRRLQQKT
QPSSS
>Mature_165_residues
MDVPSYPEHQQWMEKAIALATQAGAAGEVPVGAVIIGPDGDCIAEGENRRERDHDPTAHAEIVALRAASQVIQSWRLHEC
RLYVTLEPCPMCAGAIIQARLGLLVYGAHDPKTGAIRTVLNLPGSPCSFHKLPVIAGVLEPTCRQQLQEWFARRRLQQKT
QPSSS

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=127, Percent_Identity=33.8582677165354, Blast_Score=74, Evalue=7e-14,
Organism=Escherichia coli, GI145693172, Length=156, Percent_Identity=44.8717948717949, Blast_Score=135, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI17541138, Length=158, Percent_Identity=33.5443037974684, Blast_Score=83, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI17554608, Length=99, Percent_Identity=39.3939393939394, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17555996, Length=108, Percent_Identity=36.1111111111111, Blast_Score=74, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6322425, Length=129, Percent_Identity=31.7829457364341, Blast_Score=65, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 18039; Mature: 18039

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVPSYPEHQQWMEKAIALATQAGAAGEVPVGAVIIGPDGDCIAEGENRRERDHDPTAHA
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCEEECCCCCCCCCCCCCHHH
EIVALRAASQVIQSWRLHECRLYVTLEPCPMCAGAIIQARLGLLVYGAHDPKTGAIRTVL
HHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHCEEEECCCCCCCHHHHHHH
NLPGSPCSFHKLPVIAGVLEPTCRQQLQEWFARRRLQQKTQPSSS
CCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MDVPSYPEHQQWMEKAIALATQAGAAGEVPVGAVIIGPDGDCIAEGENRRERDHDPTAHA
CCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEECCCCCEEECCCCCCCCCCCCCHHH
EIVALRAASQVIQSWRLHECRLYVTLEPCPMCAGAIIQARLGLLVYGAHDPKTGAIRTVL
HHHHHHHHHHHHHHHCCCEEEEEEEECCCCHHHHHHHHHHHCEEEECCCCCCCHHHHHHH
NLPGSPCSFHKLPVIAGVLEPTCRQQLQEWFARRRLQQKTQPSSS
CCCCCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]