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The map label for this gene is gapA [H]

Identifier: 158334133

GI number: 158334133

Start: 917594

End: 918646

Strand: Reverse

Name: gapA [H]

Synonym: AM1_0949

Alternate gene names: 158334133

Gene position: 918646-917594 (Counterclockwise)

Preceding gene: 158334135

Following gene: 158334127

Centisome position: 14.12

GC content: 50.43

Gene sequence:

>1053_bases
ATGAGGTTCTCAATGACTATAAAAATAGGCATTAATGGGTTTGGCCGTATTGGTCGACTAGTATTCCGAGCTGGGATCAA
TAATCCCAATATTGAATTTGTCGGCATTAATGATTTAGTCCCTGCCGAGAACATCGCCTACCTACTGAAGTATGACTCAA
CCCATGGTCCCTTTCGCGGCACGGTTGCGGCCACGTCTGAGGGAATTATGGTCAATGACAAATTCATCCCCTGTACCGCG
ATTCGTAATCCAGAGGAACTGCCTTGGGGCCGGCTAGGGGCAGAGTATGTCGTGGAAGCGACAGGACTTTTCACCACCTT
CGATACGGCCTCAAAACATCTCGCTGCTGGGGCCAAGCGGGTTACTATTTCAGCCCCTACGAAAGAAGAGGATCCTGAGA
AGGTTCCGACGCTCCTTATGGGAGTTAACCATGATCTCTACAATCCCCAGCAACATACGGTTGTATCTAACGCCAGCTGT
ACCACCAATTGTCTGGCCCCCATTGCCAAAGTCATTCACGATAACTTTGGTTTTGCCGAAGGACTGATGACGACAGTTCA
TGCCATGACTGCCACCCAGCCAACAGTAGATGGCCCCAGCAAAAAAGATCTGCGAGGAGGCCGAAGTGCAGCCCAAAACA
TTATTCCGGCTTCCACCGGCGCAGCCAAAGCGGTTACCCTAGTTCTGCCTGAACTCAAAGGAAAGTTGACGGGGATGGCC
CTGCGGGTCCCGACCCCTGATGTCTCTGTTGTTGATCTCACCTTCCGCACAGAGCGTTCCACCACCTATGCCGATATTTG
TGCAGCCATGCGAACCGCTGCCTATGGGGAACTCAAAGGGATTTTAGGATATACCGAAGATGCCGTTGTCTCTACGGACT
TCACCAGTGATCCCCATTCCAGCATTTTTGATGCTGGAGCGGGTATGGAACTGAACTCTAATTTCTTTAAGGTTGTGGCT
TGGTATGACAACGAATGGGGTTACTCCAATCGCATGATTGATTTAATCCAGTCCATGGCCGCCAAGGAATCGGAAAGGAT
GGCTTTTGCCTAG

Upstream 100 bases:

>100_bases
GAACATGATTGCATCCTGTCAGGGTGATAGGACTGGCTGAGAGACATCTGATTTTCGCTGCATGAATAGGGCCTAAAGCA
AGTGCCTAGTACTCCTTCCT

Downstream 100 bases:

>100_bases
TTCGCGCTCTCATTGCTTTATGCCACACTCCCTTAACTAATGGTTGGGGGAGTGTTTTTTTTGGGAACGAGTAATGCATC
AGCCCGCTGGCGGCGCCGCT

Product: type I glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 350; Mature: 350

Protein sequence:

>350_residues
MRFSMTIKIGINGFGRIGRLVFRAGINNPNIEFVGINDLVPAENIAYLLKYDSTHGPFRGTVAATSEGIMVNDKFIPCTA
IRNPEELPWGRLGAEYVVEATGLFTTFDTASKHLAAGAKRVTISAPTKEEDPEKVPTLLMGVNHDLYNPQQHTVVSNASC
TTNCLAPIAKVIHDNFGFAEGLMTTVHAMTATQPTVDGPSKKDLRGGRSAAQNIIPASTGAAKAVTLVLPELKGKLTGMA
LRVPTPDVSVVDLTFRTERSTTYADICAAMRTAAYGELKGILGYTEDAVVSTDFTSDPHSSIFDAGAGMELNSNFFKVVA
WYDNEWGYSNRMIDLIQSMAAKESERMAFA

Sequences:

>Translated_350_residues
MRFSMTIKIGINGFGRIGRLVFRAGINNPNIEFVGINDLVPAENIAYLLKYDSTHGPFRGTVAATSEGIMVNDKFIPCTA
IRNPEELPWGRLGAEYVVEATGLFTTFDTASKHLAAGAKRVTISAPTKEEDPEKVPTLLMGVNHDLYNPQQHTVVSNASC
TTNCLAPIAKVIHDNFGFAEGLMTTVHAMTATQPTVDGPSKKDLRGGRSAAQNIIPASTGAAKAVTLVLPELKGKLTGMA
LRVPTPDVSVVDLTFRTERSTTYADICAAMRTAAYGELKGILGYTEDAVVSTDFTSDPHSSIFDAGAGMELNSNFFKVVA
WYDNEWGYSNRMIDLIQSMAAKESERMAFA
>Mature_350_residues
MRFSMTIKIGINGFGRIGRLVFRAGINNPNIEFVGINDLVPAENIAYLLKYDSTHGPFRGTVAATSEGIMVNDKFIPCTA
IRNPEELPWGRLGAEYVVEATGLFTTFDTASKHLAAGAKRVTISAPTKEEDPEKVPTLLMGVNHDLYNPQQHTVVSNASC
TTNCLAPIAKVIHDNFGFAEGLMTTVHAMTATQPTVDGPSKKDLRGGRSAAQNIIPASTGAAKAVTLVLPELKGKLTGMA
LRVPTPDVSVVDLTFRTERSTTYADICAAMRTAAYGELKGILGYTEDAVVSTDFTSDPHSSIFDAGAGMELNSNFFKVVA
WYDNEWGYSNRMIDLIQSMAAKESERMAFA

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:
GO:0005488: Glyceraldehyde-3-phosphate dehydrogenase
GO:0006006: Glyceraldehyde-3-phosphate dehydrogenase
GO:0008943: Glyceraldehyde-3-phosphate dehydrogenase
GO:0016491: Glyceraldehyde-3-phosphate dehydrogenase
GO:0016620: Glyceraldehyde-3-phosphate dehydrogenase
GO:0051287: Glyceraldehyde-3-phosphate dehydrogenase
GO:0055114: Glyceraldehyde-3-phosphate dehydrogenase

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=338, Percent_Identity=59.4674556213018, Blast_Score=406, Evalue=1e-113,
Organism=Homo sapiens, GI7657116, Length=338, Percent_Identity=56.2130177514793, Blast_Score=392, Evalue=1e-109,
Organism=Escherichia coli, GI1788079, Length=336, Percent_Identity=62.202380952381, Blast_Score=420, Evalue=1e-119,
Organism=Escherichia coli, GI1789295, Length=339, Percent_Identity=38.0530973451327, Blast_Score=247, Evalue=7e-67,
Organism=Caenorhabditis elegans, GI17534677, Length=340, Percent_Identity=58.5294117647059, Blast_Score=396, Evalue=1e-111,
Organism=Caenorhabditis elegans, GI32566163, Length=340, Percent_Identity=58.2352941176471, Blast_Score=395, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI17568413, Length=340, Percent_Identity=58.2352941176471, Blast_Score=394, Evalue=1e-110,
Organism=Caenorhabditis elegans, GI17534679, Length=340, Percent_Identity=57.9411764705882, Blast_Score=394, Evalue=1e-110,
Organism=Saccharomyces cerevisiae, GI6322409, Length=335, Percent_Identity=57.6119402985075, Blast_Score=397, Evalue=1e-111,
Organism=Saccharomyces cerevisiae, GI6321631, Length=335, Percent_Identity=56.7164179104478, Blast_Score=393, Evalue=1e-110,
Organism=Saccharomyces cerevisiae, GI6322468, Length=335, Percent_Identity=56.1194029850746, Blast_Score=385, Evalue=1e-108,
Organism=Drosophila melanogaster, GI17933600, Length=337, Percent_Identity=60.5341246290801, Blast_Score=396, Evalue=1e-110,
Organism=Drosophila melanogaster, GI18110149, Length=337, Percent_Identity=60.5341246290801, Blast_Score=396, Evalue=1e-110,
Organism=Drosophila melanogaster, GI85725000, Length=337, Percent_Identity=60.5341246290801, Blast_Score=394, Evalue=1e-110,
Organism=Drosophila melanogaster, GI22023983, Length=337, Percent_Identity=60.5341246290801, Blast_Score=394, Evalue=1e-110,
Organism=Drosophila melanogaster, GI19922412, Length=330, Percent_Identity=52.1212121212121, Blast_Score=338, Evalue=3e-93,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 37781; Mature: 37781

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFSMTIKIGINGFGRIGRLVFRAGINNPNIEFVGINDLVPAENIAYLLKYDSTHGPFRG
CCEEEEEEECCCCCHHHHHHHHEECCCCCCEEEEECCCCCCCCCEEEEEEECCCCCCCCE
TVAATSEGIMVNDKFIPCTAIRNPEELPWGRLGAEYVVEATGLFTTFDTASKHLAAGAKR
EEEECCCCEEEECCEEEEEECCCCCCCCCCCCCHHHEEEECCEEEEHHHHHHHHHCCCEE
VTISAPTKEEDPEKVPTLLMGVNHDLYNPQQHTVVSNASCTTNCLAPIAKVIHDNFGFAE
EEEECCCCCCCHHHHHHHEEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCHHH
GLMTTVHAMTATQPTVDGPSKKDLRGGRSAAQNIIPASTGAAKAVTLVLPELKGKLTGMA
HHHHHHHHHHCCCCCCCCCCCHHHCCCHHHHHHCCCCCCCCCEEEEEEEHHHCCCCCCEE
LRVPTPDVSVVDLTFRTERSTTYADICAAMRTAAYGELKGILGYTEDAVVSTDFTSDPHS
EECCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCH
SIFDAGAGMELNSNFFKVVAWYDNEWGYSNRMIDLIQSMAAKESERMAFA
HHHCCCCCCEECCCEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MRFSMTIKIGINGFGRIGRLVFRAGINNPNIEFVGINDLVPAENIAYLLKYDSTHGPFRG
CCEEEEEEECCCCCHHHHHHHHEECCCCCCEEEEECCCCCCCCCEEEEEEECCCCCCCCE
TVAATSEGIMVNDKFIPCTAIRNPEELPWGRLGAEYVVEATGLFTTFDTASKHLAAGAKR
EEEECCCCEEEECCEEEEEECCCCCCCCCCCCCHHHEEEECCEEEEHHHHHHHHHCCCEE
VTISAPTKEEDPEKVPTLLMGVNHDLYNPQQHTVVSNASCTTNCLAPIAKVIHDNFGFAE
EEEECCCCCCCHHHHHHHEEECCCCCCCCCCCEEEECCCCCHHHHHHHHHHHHCCCCHHH
GLMTTVHAMTATQPTVDGPSKKDLRGGRSAAQNIIPASTGAAKAVTLVLPELKGKLTGMA
HHHHHHHHHHCCCCCCCCCCCHHHCCCHHHHHHCCCCCCCCCEEEEEEEHHHCCCCCCEE
LRVPTPDVSVVDLTFRTERSTTYADICAAMRTAAYGELKGILGYTEDAVVSTDFTSDPHS
EECCCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCH
SIFDAGAGMELNSNFFKVVAWYDNEWGYSNRMIDLIQSMAAKESERMAFA
HHHCCCCCCEECCCEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8378350 [H]