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The map label for this gene is murA [H]

Identifier: 158334127

GI number: 158334127

Start: 910749

End: 912044

Strand: Reverse

Name: murA [H]

Synonym: AM1_0943

Alternate gene names: 158334127

Gene position: 912044-910749 (Counterclockwise)

Preceding gene: 158334133

Following gene: 158334121

Centisome position: 14.02

GC content: 50.39

Gene sequence:

>1296_bases
GTGGATCAGTCTGTTTCGACCAAAGCAAACTCGTCGATCCTTGAGGTATGGGGAGGGACACCACTCCAAGGGAAAGTCAA
CATCAGTGGAGCCAAGAACTCCGCCCTCGTGCTCATGGCTGGGGCACTTCTCTGTTCAGAACCCTGCCGTTTGCGGAATG
TTCCATCCCTTGCAGATATCCAAGGAATGGCCAAAATTCTCAAAGCCTTAGGGGTCAAAATTAAGCAAGATAACGATGTT
TTAGAGCTAGATCCGACCCACATCACCACAACGGATGCCCCCTATGAACTCGTCAGTAAGCTAAGAGCCAGTTTCTTTGC
CATTGGTCCGTTACTAGCCCGTATGGGCGTTGCCAAAGTCCCCTTACCCGGCGGCTGCGCCATTGGTGCGAGACCCGTAG
AAATTCACGTTCGAGGTCTAAAGCAACTTGGAGCCGAAGTTTACATTGAACATGGTGTCGTCCATGCCTATGCTTCTAAA
CTTAAAGGCGCCAAGATTTATCTGGATTACCCCAGTGTGGGGGCGACCGAAACCTTGATGATGGCTGCAACCCTGGCCGA
GGGGGAAACCGTTTTGGATAATGCTGCCCAAGAGCCTGAAGTTGCAGACTTAGCGAACTTCTGTATATCCATGGGAGCCA
AAATTACGGGAGCGGGCACCAAAACGATTACCATTTCTGGCGTTCCTAAACTGCACAGCACCGATTACAACATTGTGCCG
GATCGGATTGAAGCAGGCACCTTTTTGATGGCGGGAGCGATTACCCACTCTGACATTCTCCTGTCGCCTGTCGTGCCTGA
TCACCTAACTGCAGTCATTGCTAAACTCAGGTCTATCGGATTTCAATTGACACCGGATGCCCAACAGGGATTGCGGATCC
AGTCTAAAGGGGTTCATACAGGGACCGAAATTGAGACGCTTCCCTATCCGGGGTTCCCCACTGATATGCAATCCATTTTT
ATGGCTCTGCTGACCTTAAGTGAGGGAAACAGTGTTGTGACTGAAACAGTATTTGAAAACCGTTTGGGCCATGTCCCCGA
ACTGGTCAGAATGGGAGCTGATATTAGAGTTAAGGGCAATATTGCTGTTATTCATGGCGTGCCATTCTTGTCCGGAGCAC
CAGTTACAGGAACTGACTTAAGAGCAACGGCAGCACTCGTGGTTGCCGCCCTAGCCGCCAAAGGTAAAACTAGCATTGAA
GGTCTGCAGCATCTCGATCGAGGTTATTCTGATTTTGAGCAGAAGTTACGTGGTTTAGGCGCTAGGATTGAGCGGGTTCC
TGCCCCTAACGCCTAA

Upstream 100 bases:

>100_bases
CCGGTTTTAGGGTACACTCTAGACCACATTCCCCTGCAAATTTTTGGTGTGGTGTAGGCCATTGAATACTCTTAAAACCG
TTTCTTCCCCCGTTAGCATA

Downstream 100 bases:

>100_bases
ATCGATTTCGACTTTAACCCGTCCCAGCATCAAGATGCTCATGATCTCGAGGCTGGGATTTTGGTTTCGGCTTGTGTTGA
GCTTCAGGCTTGTTCAACCC

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase; UDP-N-acetylglucosamine enolpyruvyl transferase; EPT [H]

Number of amino acids: Translated: 431; Mature: 431

Protein sequence:

>431_residues
MDQSVSTKANSSILEVWGGTPLQGKVNISGAKNSALVLMAGALLCSEPCRLRNVPSLADIQGMAKILKALGVKIKQDNDV
LELDPTHITTTDAPYELVSKLRASFFAIGPLLARMGVAKVPLPGGCAIGARPVEIHVRGLKQLGAEVYIEHGVVHAYASK
LKGAKIYLDYPSVGATETLMMAATLAEGETVLDNAAQEPEVADLANFCISMGAKITGAGTKTITISGVPKLHSTDYNIVP
DRIEAGTFLMAGAITHSDILLSPVVPDHLTAVIAKLRSIGFQLTPDAQQGLRIQSKGVHTGTEIETLPYPGFPTDMQSIF
MALLTLSEGNSVVTETVFENRLGHVPELVRMGADIRVKGNIAVIHGVPFLSGAPVTGTDLRATAALVVAALAAKGKTSIE
GLQHLDRGYSDFEQKLRGLGARIERVPAPNA

Sequences:

>Translated_431_residues
MDQSVSTKANSSILEVWGGTPLQGKVNISGAKNSALVLMAGALLCSEPCRLRNVPSLADIQGMAKILKALGVKIKQDNDV
LELDPTHITTTDAPYELVSKLRASFFAIGPLLARMGVAKVPLPGGCAIGARPVEIHVRGLKQLGAEVYIEHGVVHAYASK
LKGAKIYLDYPSVGATETLMMAATLAEGETVLDNAAQEPEVADLANFCISMGAKITGAGTKTITISGVPKLHSTDYNIVP
DRIEAGTFLMAGAITHSDILLSPVVPDHLTAVIAKLRSIGFQLTPDAQQGLRIQSKGVHTGTEIETLPYPGFPTDMQSIF
MALLTLSEGNSVVTETVFENRLGHVPELVRMGADIRVKGNIAVIHGVPFLSGAPVTGTDLRATAALVVAALAAKGKTSIE
GLQHLDRGYSDFEQKLRGLGARIERVPAPNA
>Mature_431_residues
MDQSVSTKANSSILEVWGGTPLQGKVNISGAKNSALVLMAGALLCSEPCRLRNVPSLADIQGMAKILKALGVKIKQDNDV
LELDPTHITTTDAPYELVSKLRASFFAIGPLLARMGVAKVPLPGGCAIGARPVEIHVRGLKQLGAEVYIEHGVVHAYASK
LKGAKIYLDYPSVGATETLMMAATLAEGETVLDNAAQEPEVADLANFCISMGAKITGAGTKTITISGVPKLHSTDYNIVP
DRIEAGTFLMAGAITHSDILLSPVVPDHLTAVIAKLRSIGFQLTPDAQQGLRIQSKGVHTGTEIETLPYPGFPTDMQSIF
MALLTLSEGNSVVTETVFENRLGHVPELVRMGADIRVKGNIAVIHGVPFLSGAPVTGTDLRATAALVVAALAAKGKTSIE
GLQHLDRGYSDFEQKLRGLGARIERVPAPNA

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=418, Percent_Identity=50, Blast_Score=393, Evalue=1e-110,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 45415; Mature: 45415

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDQSVSTKANSSILEVWGGTPLQGKVNISGAKNSALVLMAGALLCSEPCRLRNVPSLADI
CCCCCCCCCCCCEEEECCCCCCCCEEEECCCCCCEEEEEHHHHHHCCCHHHCCCCCHHHH
QGMAKILKALGVKIKQDNDVLELDPTHITTTDAPYELVSKLRASFFAIGPLLARMGVAKV
HHHHHHHHHHCCEEECCCCEEEECCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
PLPGGCAIGARPVEIHVRGLKQLGAEVYIEHGVVHAYASKLKGAKIYLDYPSVGATETLM
CCCCCCCCCCCEEEEEEHHHHHCCHHEEHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHH
MAATLAEGETVLDNAAQEPEVADLANFCISMGAKITGAGTKTITISGVPKLHSTDYNIVP
HHHHHHCCCHHHHCCCCCCCHHHHHHHHHHCCCEEECCCCEEEEEECCCCCCCCCCCCCC
DRIEAGTFLMAGAITHSDILLSPVVPDHLTAVIAKLRSIGFQLTPDAQQGLRIQSKGVHT
CCCCCCCEEEEECCCCCCEEECCCCHHHHHHHHHHHHHCCCEECCCHHHCCEEECCCCCC
GTEIETLPYPGFPTDMQSIFMALLTLSEGNSVVTETVFENRLGHVPELVRMGADIRVKGN
CCCEEECCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHCCCCEEEECC
IAVIHGVPFLSGAPVTGTDLRATAALVVAALAAKGKTSIEGLQHLDRGYSDFEQKLRGLG
EEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHC
ARIERVPAPNA
HHHHCCCCCCC
>Mature Secondary Structure
MDQSVSTKANSSILEVWGGTPLQGKVNISGAKNSALVLMAGALLCSEPCRLRNVPSLADI
CCCCCCCCCCCCEEEECCCCCCCCEEEECCCCCCEEEEEHHHHHHCCCHHHCCCCCHHHH
QGMAKILKALGVKIKQDNDVLELDPTHITTTDAPYELVSKLRASFFAIGPLLARMGVAKV
HHHHHHHHHHCCEEECCCCEEEECCCEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCC
PLPGGCAIGARPVEIHVRGLKQLGAEVYIEHGVVHAYASKLKGAKIYLDYPSVGATETLM
CCCCCCCCCCCEEEEEEHHHHHCCHHEEHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHH
MAATLAEGETVLDNAAQEPEVADLANFCISMGAKITGAGTKTITISGVPKLHSTDYNIVP
HHHHHHCCCHHHHCCCCCCCHHHHHHHHHHCCCEEECCCCEEEEEECCCCCCCCCCCCCC
DRIEAGTFLMAGAITHSDILLSPVVPDHLTAVIAKLRSIGFQLTPDAQQGLRIQSKGVHT
CCCCCCCEEEEECCCCCCEEECCCCHHHHHHHHHHHHHCCCEECCCHHHCCEEECCCCCC
GTEIETLPYPGFPTDMQSIFMALLTLSEGNSVVTETVFENRLGHVPELVRMGADIRVKGN
CCCEEECCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHCCCCEEEECC
IAVIHGVPFLSGAPVTGTDLRATAALVVAALAAKGKTSIEGLQHLDRGYSDFEQKLRGLG
EEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHC
ARIERVPAPNA
HHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA