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The map label for this gene is atpA

Identifier: 158334080

GI number: 158334080

Start: 865090

End: 866607

Strand: Direct

Name: atpA

Synonym: AM1_0896

Alternate gene names: 158334080

Gene position: 865090-866607 (Clockwise)

Preceding gene: 158334079

Following gene: 158334081

Centisome position: 13.3

GC content: 51.65

Gene sequence:

>1518_bases
ATGGTAAGCATCAGACCCGACGAAATTAGCAATATTATTCGCCAACAGATTGAACAATACGACCAGCAAGTCAAAGTTGA
CAATGTTGGCACCGTCCTCCAGGTGGGTGACGGTATCGCCCGTGTTTATGGCCTAGAACAAGCCATGGCCGGGGAACTTC
TAGACTTTGAGGACGGTACTGTCGGTATCGCCCTAAACCTGGAAGAAGACAATGTGGGTGCGGTGCTCATGGGAGACGGT
CGTGACCTGCAGGAAGGCAGCACGGTGCGCTCCACGGGCAAAATCGCCCAGATTCCCGTGGGTGATGCTCTGATTGGTCG
CGTTCTAGATGCTCTCGCTCGCCCTATCGATGGTAAAGGCGACATCAACACTTCTGAAACTCGCCTGATTGAGTCCCCCG
CTCCTGGCATTATTGAGCGGAAATCTGTGTATGAGCCCATGCAAACGGGTATCACTGCGATTGACTCCATGGTGCCCATT
GGCCGAGGTCAGCGTGAGTTGATTATTGGTGACCGTCAAACCGGTAAGACCGCCGTTGCCATTGACACCATCCTCAACCA
AAAGTCTGAAGATGTGATTTGTGTCTACGTCGCCATCGGTCAGAAAGCCTCTACCGTGGCTCAAGTGGTTGAAGTCTTAA
GAGAGCGGGGTGCCCTTGACTACACCGTTGTGGTGGCTGCCAACGCCAACGACCCTGCAACGCTACAATATTTGGCTCCT
TATACCGGTGCTGCCATTGCTGAGTACTTTATGTACAACGGCAAGCACACCTTGGTGATCTACGATGACCTTTCCAAGCA
AGCTCAGGCCTATCGTCAGATGTCTCTACTTCTCCGTCGTCCACCCGGACGTGAGGCTTATCCTGGTGATGTGTTCTATC
TCCACTCTCGCTTGTTGGAGCGGGCAGCCAAGCTCAGTCCCGAATTGGGTGAAGGGAGTATGACCGCCCTACCGATTGTG
GAAACTCAAGCGGGTGACGTGTCGGCCTATATTCCTACCAATGTTATTTCCATTACCGACGGTCAGATTTTCTTGTCTTC
TGACTTGTTCAACGCTGGCTTACGTCCTGCCATTAACGCCGGTATTTCCGTGTCCCGAGTGGGATCTGCCGCTCAAATCA
AAGCCATGAAGCAGGTCGCCGGTAAGCTAAAGCTGGAATTGGCTCAGTTTGCTGAACTAGAAGCATTCGCTCAGTTTGCC
TCTGACCTAGACCAAGCTACCCAGAATCAGTTGGCTCGGGGTGCTCGTCTGCGGGAAATTCTGAAGCAGCCTCAATATTC
TCCATTACCAGTAGAAGAGATGGTTGCAGTCATTTATGCCGGTACCAATGGCTATCTGGATGATGTTCCTACTGATAAAG
TGACGGAGTTCGTTCAAGGTATGCGGGATGACCTGAAAGCTAACCATGCGAAGTATGGCGAGCTGGTCCGCAGCGAGAAG
AAAATGGGTGACGAGGCCGAAGGAATTCTCAAAACAGCCATTGCTGACTTTAAGAAATCTTTTATGGCTGCGGTCTAG

Upstream 100 bases:

>100_bases
AATTCTTCTATAACAAGCCTGTCTTAAGGTAATGGCAATTTTCTTAATTGCCGCTTAAGTTGTTTGACCTTTACCCACAT
CACAAATCAGAGCAAGTCCC

Downstream 100 bases:

>100_bases
GAGGGAATTATGCCAAACCTCAAATCGATTCGTGATCGTATTTCAACGGTCAAGAATACTAAAAAAATTACCGAGGCGAT
GCGGCTAGTGGCCGCCGCCA

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha 1; F-ATPase subunit alpha 1

Number of amino acids: Translated: 505; Mature: 505

Protein sequence:

>505_residues
MVSIRPDEISNIIRQQIEQYDQQVKVDNVGTVLQVGDGIARVYGLEQAMAGELLDFEDGTVGIALNLEEDNVGAVLMGDG
RDLQEGSTVRSTGKIAQIPVGDALIGRVLDALARPIDGKGDINTSETRLIESPAPGIIERKSVYEPMQTGITAIDSMVPI
GRGQRELIIGDRQTGKTAVAIDTILNQKSEDVICVYVAIGQKASTVAQVVEVLRERGALDYTVVVAANANDPATLQYLAP
YTGAAIAEYFMYNGKHTLVIYDDLSKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSPELGEGSMTALPIV
ETQAGDVSAYIPTNVISITDGQIFLSSDLFNAGLRPAINAGISVSRVGSAAQIKAMKQVAGKLKLELAQFAELEAFAQFA
SDLDQATQNQLARGARLREILKQPQYSPLPVEEMVAVIYAGTNGYLDDVPTDKVTEFVQGMRDDLKANHAKYGELVRSEK
KMGDEAEGILKTAIADFKKSFMAAV

Sequences:

>Translated_505_residues
MVSIRPDEISNIIRQQIEQYDQQVKVDNVGTVLQVGDGIARVYGLEQAMAGELLDFEDGTVGIALNLEEDNVGAVLMGDG
RDLQEGSTVRSTGKIAQIPVGDALIGRVLDALARPIDGKGDINTSETRLIESPAPGIIERKSVYEPMQTGITAIDSMVPI
GRGQRELIIGDRQTGKTAVAIDTILNQKSEDVICVYVAIGQKASTVAQVVEVLRERGALDYTVVVAANANDPATLQYLAP
YTGAAIAEYFMYNGKHTLVIYDDLSKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSPELGEGSMTALPIV
ETQAGDVSAYIPTNVISITDGQIFLSSDLFNAGLRPAINAGISVSRVGSAAQIKAMKQVAGKLKLELAQFAELEAFAQFA
SDLDQATQNQLARGARLREILKQPQYSPLPVEEMVAVIYAGTNGYLDDVPTDKVTEFVQGMRDDLKANHAKYGELVRSEK
KMGDEAEGILKTAIADFKKSFMAAV
>Mature_505_residues
MVSIRPDEISNIIRQQIEQYDQQVKVDNVGTVLQVGDGIARVYGLEQAMAGELLDFEDGTVGIALNLEEDNVGAVLMGDG
RDLQEGSTVRSTGKIAQIPVGDALIGRVLDALARPIDGKGDINTSETRLIESPAPGIIERKSVYEPMQTGITAIDSMVPI
GRGQRELIIGDRQTGKTAVAIDTILNQKSEDVICVYVAIGQKASTVAQVVEVLRERGALDYTVVVAANANDPATLQYLAP
YTGAAIAEYFMYNGKHTLVIYDDLSKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLERAAKLSPELGEGSMTALPIV
ETQAGDVSAYIPTNVISITDGQIFLSSDLFNAGLRPAINAGISVSRVGSAAQIKAMKQVAGKLKLELAQFAELEAFAQFA
SDLDQATQNQLARGARLREILKQPQYSPLPVEEMVAVIYAGTNGYLDDVPTDKVTEFVQGMRDDLKANHAKYGELVRSEK
KMGDEAEGILKTAIADFKKSFMAAV

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cellular thylakoid membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=504, Percent_Identity=59.5238095238095, Blast_Score=604, Evalue=1e-173,
Organism=Homo sapiens, GI4757810, Length=504, Percent_Identity=59.5238095238095, Blast_Score=604, Evalue=1e-173,
Organism=Homo sapiens, GI19913428, Length=301, Percent_Identity=30.8970099667774, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI19913426, Length=301, Percent_Identity=30.2325581395349, Blast_Score=116, Evalue=5e-26,
Organism=Homo sapiens, GI32189394, Length=313, Percent_Identity=25.5591054313099, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI19913424, Length=355, Percent_Identity=25.9154929577465, Blast_Score=79, Evalue=9e-15,
Organism=Escherichia coli, GI1790172, Length=504, Percent_Identity=55.1587301587302, Blast_Score=555, Evalue=1e-159,
Organism=Escherichia coli, GI1788251, Length=290, Percent_Identity=32.7586206896552, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1790170, Length=416, Percent_Identity=24.0384615384615, Blast_Score=107, Evalue=1e-24,
Organism=Caenorhabditis elegans, GI71988063, Length=502, Percent_Identity=58.9641434262948, Blast_Score=602, Evalue=1e-172,
Organism=Caenorhabditis elegans, GI71988080, Length=502, Percent_Identity=58.9641434262948, Blast_Score=601, Evalue=1e-172,
Organism=Caenorhabditis elegans, GI71988074, Length=502, Percent_Identity=55.5776892430279, Blast_Score=551, Evalue=1e-157,
Organism=Caenorhabditis elegans, GI17510931, Length=437, Percent_Identity=25.858123569794, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI17570191, Length=350, Percent_Identity=27.4285714285714, Blast_Score=114, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI25144756, Length=418, Percent_Identity=23.9234449760766, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI17565854, Length=254, Percent_Identity=28.740157480315, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=62, Blast_Score=75, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI71988068, Length=81, Percent_Identity=39.5061728395062, Blast_Score=70, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6319370, Length=505, Percent_Identity=58.4158415841584, Blast_Score=597, Evalue=1e-171,
Organism=Saccharomyces cerevisiae, GI6319603, Length=336, Percent_Identity=31.547619047619, Blast_Score=130, Evalue=7e-31,
Organism=Saccharomyces cerevisiae, GI6322581, Length=424, Percent_Identity=25.7075471698113, Blast_Score=109, Evalue=1e-24,
Organism=Drosophila melanogaster, GI24658560, Length=505, Percent_Identity=60, Blast_Score=606, Evalue=1e-173,
Organism=Drosophila melanogaster, GI281361666, Length=294, Percent_Identity=29.5918367346939, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24646341, Length=294, Percent_Identity=29.5918367346939, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI17136796, Length=294, Percent_Identity=29.5918367346939, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24638766, Length=373, Percent_Identity=25.4691689008043, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI28574560, Length=415, Percent_Identity=25.7831325301205, Blast_Score=101, Evalue=1e-21,
Organism=Drosophila melanogaster, GI24583988, Length=255, Percent_Identity=28.2352941176471, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24583986, Length=255, Percent_Identity=28.2352941176471, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24583984, Length=255, Percent_Identity=28.2352941176471, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24583992, Length=255, Percent_Identity=28.2352941176471, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI20129479, Length=242, Percent_Identity=28.9256198347107, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA1_ACAM1 (B0BZL2)

Other databases:

- EMBL:   CP000828
- RefSeq:   YP_001515252.1
- ProteinModelPortal:   B0BZL2
- SMR:   B0BZL2
- GeneID:   5679722
- GenomeReviews:   CP000828_GR
- KEGG:   amr:AM1_0896
- HOGENOM:   HBG565875
- OMA:   GSDRDIK
- ProtClustDB:   PRK09281
- BioCyc:   AMAR329726:AM1_0896-MONOMER
- HAMAP:   MF_01346
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 54612; Mature: 54612

Theoretical pI: Translated: 4.59; Mature: 4.59

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSIRPDEISNIIRQQIEQYDQQVKVDNVGTVLQVGDGIARVYGLEQAMAGELLDFEDGT
CCCCCHHHHHHHHHHHHHHHHHHEECCCCCCHHHHCCHHHHHHHHHHHHHCCCEECCCCE
VGIALNLEEDNVGAVLMGDGRDLQEGSTVRSTGKIAQIPVGDALIGRVLDALARPIDGKG
EEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHCCCCCCCC
DINTSETRLIESPAPGIIERKSVYEPMQTGITAIDSMVPIGRGQRELIIGDRQTGKTAVA
CCCCCHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEE
IDTILNQKSEDVICVYVAIGQKASTVAQVVEVLRERGALDYTVVVAANANDPATLQYLAP
HHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCEEEEECC
YTGAAIAEYFMYNGKHTLVIYDDLSKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLE
CHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
RAAKLSPELGEGSMTALPIVETQAGDVSAYIPTNVISITDGQIFLSSDLFNAGLRPAINA
HHHHCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCCEEEECCHHHCCCCHHHHC
GISVSRVGSAAQIKAMKQVAGKLKLELAQFAELEAFAQFASDLDQATQNQLARGARLREI
CCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKQPQYSPLPVEEMVAVIYAGTNGYLDDVPTDKVTEFVQGMRDDLKANHAKYGELVRSEK
HHCCCCCCCCHHHHEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
KMGDEAEGILKTAIADFKKSFMAAV
HCCCHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MVSIRPDEISNIIRQQIEQYDQQVKVDNVGTVLQVGDGIARVYGLEQAMAGELLDFEDGT
CCCCCHHHHHHHHHHHHHHHHHHEECCCCCCHHHHCCHHHHHHHHHHHHHCCCEECCCCE
VGIALNLEEDNVGAVLMGDGRDLQEGSTVRSTGKIAQIPVGDALIGRVLDALARPIDGKG
EEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHCCCCCCCC
DINTSETRLIESPAPGIIERKSVYEPMQTGITAIDSMVPIGRGQRELIIGDRQTGKTAVA
CCCCCHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEE
IDTILNQKSEDVICVYVAIGQKASTVAQVVEVLRERGALDYTVVVAANANDPATLQYLAP
HHHHHCCCCCCEEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCCEEEEECC
YTGAAIAEYFMYNGKHTLVIYDDLSKQAQAYRQMSLLLRRPPGREAYPGDVFYLHSRLLE
CHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHH
RAAKLSPELGEGSMTALPIVETQAGDVSAYIPTNVISITDGQIFLSSDLFNAGLRPAINA
HHHHCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCCEEEECCHHHCCCCHHHHC
GISVSRVGSAAQIKAMKQVAGKLKLELAQFAELEAFAQFASDLDQATQNQLARGARLREI
CCCHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKQPQYSPLPVEEMVAVIYAGTNGYLDDVPTDKVTEFVQGMRDDLKANHAKYGELVRSEK
HHCCCCCCCCHHHHEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHHHHHHHHH
KMGDEAEGILKTAIADFKKSFMAAV
HCCCHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA