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The map label for this gene is spoVD [H]

Identifier: 158334033

GI number: 158334033

Start: 826959

End: 828758

Strand: Reverse

Name: spoVD [H]

Synonym: AM1_0847

Alternate gene names: 158334033

Gene position: 828758-826959 (Counterclockwise)

Preceding gene: 158334034

Following gene: 158334032

Centisome position: 12.74

GC content: 48.89

Gene sequence:

>1800_bases
ATGCCCACTCCCTCTCACCCCATTCAAGATCGTCGGGCCGCAATCAAGGCTCGAATCCAAACGAAGCAGCCCCATCGAGT
TCCAAATCAGCGATTACGCTTATTTCTTGTTTGGTTGGTGGTATTTGGAGGCATTGTGGGCTTGTTAGCCCGTTTAGTCT
ATTTGCAAGTCAGTGCGGCCCCGTTTCTCCGAACAAAAGCCCAAAATCAGCAGCTAGGTAGTCTGCCTGAACGTACCTTT
CGTTATCCGATTGTCGATAGCCAGGGGAATCTACTGGCTAAGGATGAACCGGTCTTTCGTCTATTTGCCCATCCCTTTTT
ATTCCAAAAACAGCCAGATGAAATCGCGCAGGCTCTAGCTCCGGTCCTTGACCGCTCTTCCGATTCTCTGATGGAGCTAT
TCAAAACTGGAGAAAGTGGGATTCCAATTGGGTATCGCTTGTCGGAAACCGAAGCGGAAAAAATCAACAATCTCTATTTA
GATGGATTAGAAATTACTCGGGAATGGCAACGGGTTTATCCCCAATCGGAACTAACTTCGGGGCTGGTTGGGTATGTCAA
CACCGAAAATCAAGGACAGTCTGGCATTGAATATAGCCAGCAGCCTCTCTTAAAGGGAGATCCGATTCCCTTACTGGTAG
CGAGGGATGGCCAGGGCAAGCTTTTACCGGATCGATTTCCCTTAGAGTCCCTGAATGCCAATGACCTGACTCTGAAACTA
ACCCTAGATACCCGACTCCAGCGGTCAGCTCGACAGGCTCTGCATAAAAAGATGGCAGAGTTTCGCGCTAAGCGAGGCAC
CGTTATTGTGATGGATGTTGAGGATGGCTCCCTTAAGGCTTTGGCCTCGGAACCCTCCTTTAATCCCCAGCGTTATTTTG
AAGCGAATACCGAGCTGTTTAAAAACTGGGCCATTTCGGATCTCTATGAGCCAGGGTCGACCTTTAAGCCGATCAATATT
GCGATCGCATTAGAATCCAATGCCATCAAAGCCGACAGTGTTTTCCATGATGGCGGTCAAATTACCGTAGGGGGCTGGCC
AATTAATAATGCCGACAACTCAGGTCACGGCAACCTTTCCATTACTGGCATCTTGGAATATTCCAGCAACGTGGGCATGG
TTCATGTCATGCAGCGGATGGATCGATCGGCTTACTACAATTACCTGAAAAAAATTGGGATTGGCCAAATTACGGGTACT
GATCTTCCCTTTGAAACCCCTGGCCAGTTTAAGGATAAGCAGCAGTTTTTAGACTATCCCATTGAAGCAGCAACCGCAGC
TTTCGGCCAAGGATTTTCGGTAACGCCTCTACAAATGGCGCAGCTCCATGCCGCGATCGCTAATGGGGGCGAGTTAGTAA
CTCCCCATGTGGTCGATGGTCTGTATAACCCTGCTGGCAAGAAAACCAAGGGATTAAACCTAATTCAACCCCGACGCATC
TTTTCGAAAAATACAGCCGCCAAAGTTCGGACTATGATGGGCAGCGTTGTCCAAAACGGCACGGGTAAACCCGCCAAAAT
TCCCGGCTATCGCTTAGGGGGTAAAACAGGAACAGCCCAAAAAGCAGATAGTGGTACCTACAGCAATGCCCGCATTACCA
GCTTTGTCGCCTCATTTCCTTTGGAGTCTCCTAAATATGTGGTGTTGGCCGTAGTGGATGAACCGCAGGGGGGCAATGCT
TATGGCTCAACAGTTGCCGCTCCGGTTGTGAAGTCAGTGTTGGAAACTTTGATTAGCGTTAAGGGCATTCCTCCCAGTCA
TCCTGCAGAATTGAAGGCAAAACCAAAACCATCTCGTTAA

Upstream 100 bases:

>100_bases
CCCGGCGCGTCCGGCTCAGCCTGCGCCTTCTCAGGGAAATGGCATCACCCATATTGATGTTGCTCCGATTGGTTATTAAG
TCCAACTTCTTTGCAAGTTT

Downstream 100 bases:

>100_bases
AGAACCTAAGCAAATCGCCCTTGCTAGCTTCTCTCTCCAGTTCAAGGTGGCGCTTAAACAAGGTACATAAAGCAAAATAA
CAACCTTCTCATTAAGTGGG

Product: penicillin-binding protein

Products: NA

Alternate protein names: Sporulation-specific penicillin-binding protein [H]

Number of amino acids: Translated: 599; Mature: 598

Protein sequence:

>599_residues
MPTPSHPIQDRRAAIKARIQTKQPHRVPNQRLRLFLVWLVVFGGIVGLLARLVYLQVSAAPFLRTKAQNQQLGSLPERTF
RYPIVDSQGNLLAKDEPVFRLFAHPFLFQKQPDEIAQALAPVLDRSSDSLMELFKTGESGIPIGYRLSETEAEKINNLYL
DGLEITREWQRVYPQSELTSGLVGYVNTENQGQSGIEYSQQPLLKGDPIPLLVARDGQGKLLPDRFPLESLNANDLTLKL
TLDTRLQRSARQALHKKMAEFRAKRGTVIVMDVEDGSLKALASEPSFNPQRYFEANTELFKNWAISDLYEPGSTFKPINI
AIALESNAIKADSVFHDGGQITVGGWPINNADNSGHGNLSITGILEYSSNVGMVHVMQRMDRSAYYNYLKKIGIGQITGT
DLPFETPGQFKDKQQFLDYPIEAATAAFGQGFSVTPLQMAQLHAAIANGGELVTPHVVDGLYNPAGKKTKGLNLIQPRRI
FSKNTAAKVRTMMGSVVQNGTGKPAKIPGYRLGGKTGTAQKADSGTYSNARITSFVASFPLESPKYVVLAVVDEPQGGNA
YGSTVAAPVVKSVLETLISVKGIPPSHPAELKAKPKPSR

Sequences:

>Translated_599_residues
MPTPSHPIQDRRAAIKARIQTKQPHRVPNQRLRLFLVWLVVFGGIVGLLARLVYLQVSAAPFLRTKAQNQQLGSLPERTF
RYPIVDSQGNLLAKDEPVFRLFAHPFLFQKQPDEIAQALAPVLDRSSDSLMELFKTGESGIPIGYRLSETEAEKINNLYL
DGLEITREWQRVYPQSELTSGLVGYVNTENQGQSGIEYSQQPLLKGDPIPLLVARDGQGKLLPDRFPLESLNANDLTLKL
TLDTRLQRSARQALHKKMAEFRAKRGTVIVMDVEDGSLKALASEPSFNPQRYFEANTELFKNWAISDLYEPGSTFKPINI
AIALESNAIKADSVFHDGGQITVGGWPINNADNSGHGNLSITGILEYSSNVGMVHVMQRMDRSAYYNYLKKIGIGQITGT
DLPFETPGQFKDKQQFLDYPIEAATAAFGQGFSVTPLQMAQLHAAIANGGELVTPHVVDGLYNPAGKKTKGLNLIQPRRI
FSKNTAAKVRTMMGSVVQNGTGKPAKIPGYRLGGKTGTAQKADSGTYSNARITSFVASFPLESPKYVVLAVVDEPQGGNA
YGSTVAAPVVKSVLETLISVKGIPPSHPAELKAKPKPSR
>Mature_598_residues
PTPSHPIQDRRAAIKARIQTKQPHRVPNQRLRLFLVWLVVFGGIVGLLARLVYLQVSAAPFLRTKAQNQQLGSLPERTFR
YPIVDSQGNLLAKDEPVFRLFAHPFLFQKQPDEIAQALAPVLDRSSDSLMELFKTGESGIPIGYRLSETEAEKINNLYLD
GLEITREWQRVYPQSELTSGLVGYVNTENQGQSGIEYSQQPLLKGDPIPLLVARDGQGKLLPDRFPLESLNANDLTLKLT
LDTRLQRSARQALHKKMAEFRAKRGTVIVMDVEDGSLKALASEPSFNPQRYFEANTELFKNWAISDLYEPGSTFKPINIA
IALESNAIKADSVFHDGGQITVGGWPINNADNSGHGNLSITGILEYSSNVGMVHVMQRMDRSAYYNYLKKIGIGQITGTD
LPFETPGQFKDKQQFLDYPIEAATAAFGQGFSVTPLQMAQLHAAIANGGELVTPHVVDGLYNPAGKKTKGLNLIQPRRIF
SKNTAAKVRTMMGSVVQNGTGKPAKIPGYRLGGKTGTAQKADSGTYSNARITSFVASFPLESPKYVVLAVVDEPQGGNAY
GSTVAAPVVKSVLETLISVKGIPPSHPAELKAKPKPSR

Specific function: Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex, which is a modified form of peptidoglycan. Pore cortex formation is determined primarily by the mother cell [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PASTA domain [H]

Homologues:

Organism=Escherichia coli, GI1786272, Length=589, Percent_Identity=30.2207130730051, Blast_Score=234, Evalue=1e-62,
Organism=Escherichia coli, GI1786854, Length=635, Percent_Identity=24.4094488188976, Blast_Score=105, Evalue=8e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005543
- InterPro:   IPR005311
- InterPro:   IPR001460
- InterPro:   IPR011927 [H]

Pfam domain/function: PF03793 PASTA; PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 65602; Mature: 65471

Theoretical pI: Translated: 9.93; Mature: 9.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTPSHPIQDRRAAIKARIQTKQPHRVPNQRLRLFLVWLVVFGGIVGLLARLVYLQVSAA
CCCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PFLRTKAQNQQLGSLPERTFRYPIVDSQGNLLAKDEPVFRLFAHPFLFQKQPDEIAQALA
HHHHHHCCCCHHCCCCHHHEECCEECCCCCEEECCCCHHHHHHCCHHCCCCHHHHHHHHH
PVLDRSSDSLMELFKTGESGIPIGYRLSETEAEKINNLYLDGLEITREWQRVYPQSELTS
HHHCCCHHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHEECHHHHHHHHHHHCCHHHHCC
GLVGYVNTENQGQSGIEYSQQPLLKGDPIPLLVARDGQGKLLPDRFPLESLNANDLTLKL
CCEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCEEEEE
TLDTRLQRSARQALHKKMAEFRAKRGTVIVMDVEDGSLKALASEPSFNPQRYFEANTELF
EECHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCCCCHHHHHHCCHHHH
KNWAISDLYEPGSTFKPINIAIALESNAIKADSVFHDGGQITVGGWPINNADNSGHGNLS
HHCCHHHHCCCCCCCCCEEEEEEEECCCEECCCEEECCCEEEECCEECCCCCCCCCCCEE
ITGILEYSSNVGMVHVMQRMDRSAYYNYLKKIGIGQITGTDLPFETPGQFKDKQQFLDYP
EEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHCCC
IEAATAAFGQGFSVTPLQMAQLHAAIANGGELVTPHVVDGLYNPAGKKTKGLNLIQPRRI
HHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEECHHHHHHCCCCCCCCCCCCCCCCCHHH
FSKNTAAKVRTMMGSVVQNGTGKPAKIPGYRLGGKTGTAQKADSGTYSNARITSFVASFP
HCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHCC
LESPKYVVLAVVDEPQGGNAYGSTVAAPVVKSVLETLISVKGIPPSHPAELKAKPKPSR
CCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
PTPSHPIQDRRAAIKARIQTKQPHRVPNQRLRLFLVWLVVFGGIVGLLARLVYLQVSAA
CCCCCCHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PFLRTKAQNQQLGSLPERTFRYPIVDSQGNLLAKDEPVFRLFAHPFLFQKQPDEIAQALA
HHHHHHCCCCHHCCCCHHHEECCEECCCCCEEECCCCHHHHHHCCHHCCCCHHHHHHHHH
PVLDRSSDSLMELFKTGESGIPIGYRLSETEAEKINNLYLDGLEITREWQRVYPQSELTS
HHHCCCHHHHHHHHHCCCCCCCCEEEECHHHHHHHHHHEECHHHHHHHHHHHCCHHHHCC
GLVGYVNTENQGQSGIEYSQQPLLKGDPIPLLVARDGQGKLLPDRFPLESLNANDLTLKL
CCEEEEECCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCEEEEE
TLDTRLQRSARQALHKKMAEFRAKRGTVIVMDVEDGSLKALASEPSFNPQRYFEANTELF
EECHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEEECCCCCCHHHHHHCCHHHH
KNWAISDLYEPGSTFKPINIAIALESNAIKADSVFHDGGQITVGGWPINNADNSGHGNLS
HHCCHHHHCCCCCCCCCEEEEEEEECCCEECCCEEECCCEEEECCEECCCCCCCCCCCEE
ITGILEYSSNVGMVHVMQRMDRSAYYNYLKKIGIGQITGTDLPFETPGQFKDKQQFLDYP
EEEEEEECCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHHCCC
IEAATAAFGQGFSVTPLQMAQLHAAIANGGELVTPHVVDGLYNPAGKKTKGLNLIQPRRI
HHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCEECHHHHHHCCCCCCCCCCCCCCCCCHHH
FSKNTAAKVRTMMGSVVQNGTGKPAKIPGYRLGGKTGTAQKADSGTYSNARITSFVASFP
HCCCHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCCCCCCCCCCCCCCHHHHHHHHHCC
LESPKYVVLAVVDEPQGGNAYGSTVAAPVVKSVLETLISVKGIPPSHPAELKAKPKPSR
CCCCCEEEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8289242; 9384377; 8244929; 8436954 [H]