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The map label for this gene is fusA [C]

Identifier: 158333793

GI number: 158333793

Start: 589587

End: 591605

Strand: Direct

Name: fusA [C]

Synonym: AM1_0601

Alternate gene names: 158333793

Gene position: 589587-591605 (Clockwise)

Preceding gene: 158333791

Following gene: 158333794

Centisome position: 9.07

GC content: 50.37

Gene sequence:

>2019_bases
ATGAATAGTTTCCGAAATATCGCCCTGGTGGGTCCCTATTCCAGTGGCAAAACAACGCTCCTCGAAAGTTTACTTCATGT
CACGGAGGTCACCACCCGAAAAGGGTCCGTAAAAGAAGGCAACACCGTGGGGGATGCAAGTGCTGAAGCCCGGGAGCGCC
AAATGAGTACAGAAGTAACGGCTGCCAGTTTTGAACATGGCGGCCTTTCTTTTACTTTTTTAGACTGCCCAGGTTCCGTC
GAGTTATTGCAAGAAACCCTTAACTGTCTGGTTGGGGTTGATGCTGCGGTGGTGGTTTGTGAACCGGAACCCCAGAAGGT
TCTCACTCTGGCCCCCTTGTTTCAAACCCTAGATGAATGGGAGATTCCCCATCTGGTGTTTATCAATAAAATGGATCGCG
CCAATTCCCCCTTTAGCGAAGTCTTGGATGCCCTCAAGCAGGTCTCCAGCCGTCCACTGGTCCTCCATCAATATCCCATT
GGCCAAAATGAAGACCTTCAGGGATTCATCGATCTCGTTTCGGAACAAGCGTTCCATTACCATCCCGACTCTCCAGCAGA
TCCGATGCCTCTACCCGCAGAGTTGGCAGACCAGGAAAAGGCGGCCCATACAGAAATGTTGGAAGCGCTCGCCGATTTTG
ATGATCACCTTTTAGAAGAATTACTAGAAGATATCGAGCCCCCTCAATCTGAAGTCCTACAAGATCTGAAAACAGAACTC
GGGGCTGATTTAATTGTACCCGTCTTTGTGGGAGTGGCCGAGGCTGGGTATGGTGTACGCCCTCTCCTGGATGCCCTAGA
GAAGGAAGCACCTGAGGCGAATGACACGGCTAAATCTCGTGAACTAGAGCCCAGCTCAGATCGTCTGGTTGCCCAGGTCC
TGAAAAACTATTTCTCTCCCCAGGGCGGCAAACTATCCCTAGTGCGAGTGTGGCAAGGCACCCTGACCGATGGCATGATC
TTAAATCAAGTTCGAGTGGGAGGCATCTATCGTTTATTGGGGCAACAGCAAAAAACGCTTACCCAAGCAGAGGCTGGGGA
CATTGTGGCTTTAAGCCGTTTAGATGGCGTCAAAACGGGGGATACGCTGGTTGTTGTCGATGGATCTGCCGTGCCGGATT
TACCCACGGCTCAACAGCTAGAACCGGTTTACTCCCTGGCGATTGCTCCCAGAGACCGCAAAGACGAAGTTAAGCTCAGT
AGTGCCGTTAGTAAACTTCTGGAAGAAGATCCCAGCTTAAGTTGGGAGCATCGAGAGACGACCCATGAGATCATTCTGTG
GGGACAAGGCGATATCCACTTAAAAATTGCCATCGATCGGCTAGGACGAAAGCATAAGTTACCGATTAAAACCCATACCC
CCCATGTCCCCTATAAGGAAAGTATTCGGAAGTCTGCCTCTAGTCATGGTCGCTATAAGCACCAAACGGGTGGCCATGGT
CAATTTGGGGATGTGCGGTTAGATATCAAACCCAAAGCTAGAGGAGAAGGCTTTACGTTTAAGGAAACCATTGTAGGAGG
GGTAGTCCCTCGTCAATATATTCCAGGTGTAGAGATGGGAGTTCGTGAATTTCTCCAGCATGGCGTCTTGGGTTTCCCCA
TCGTGGATATTGATGTCACCCTGACGGATGGGTCCTACCACTCTGTGGATAGCTCAGAACAGGCGTTTAAGCAGGCTGCT
CGGATTGCCATGCAGTCTGGACTTCCCAACTGTCAGCCTGTGCTTTTGGAACCCATTGAGCGGGTGATCTTGTCAACGCC
CACGAAGTTCACGTCTCAGGTCCTGCGCTTGATTAGCAATCATCGAGGCCAGGTTCTAGGCTATGAAGGCAAAAGCGGTT
GGGATAGCTGGGATGAAATCTCGGCCTACTTACCGATGGCAGAGATGCAAAGTCTGATTATTGAGTTGAGATCCCTCACT
CAAGGGGTGGGCTTCTTTATTTGGCGAGACGACCACTTAGAAGAAGTACCCGACAAAGTGGCTGAACGTGTTTTGGCAAG
AGTCGAAACAGAATTCTAA

Upstream 100 bases:

>100_bases
CTTCATTCATGAGACTGAGATTTACCCCTTCTAGTTTCAATTTTCTTCATTTTGCAAGCTGTGCTTGATCGCAACACTAT
CGTCCATCAACGAGGCAACT

Downstream 100 bases:

>100_bases
GGTTTTCCTCGTCTTTCTCCGAATTATTGTGATGCGGTCTGTTGGTATCAACCGCATCACTTTTTTTGGGAATTCCTGTA
GATTTACAAACCAATTTCTC

Product: elongation factor G

Products: GDP; phosphate

Alternate protein names: NA

Number of amino acids: Translated: 672; Mature: 672

Protein sequence:

>672_residues
MNSFRNIALVGPYSSGKTTLLESLLHVTEVTTRKGSVKEGNTVGDASAEARERQMSTEVTAASFEHGGLSFTFLDCPGSV
ELLQETLNCLVGVDAAVVVCEPEPQKVLTLAPLFQTLDEWEIPHLVFINKMDRANSPFSEVLDALKQVSSRPLVLHQYPI
GQNEDLQGFIDLVSEQAFHYHPDSPADPMPLPAELADQEKAAHTEMLEALADFDDHLLEELLEDIEPPQSEVLQDLKTEL
GADLIVPVFVGVAEAGYGVRPLLDALEKEAPEANDTAKSRELEPSSDRLVAQVLKNYFSPQGGKLSLVRVWQGTLTDGMI
LNQVRVGGIYRLLGQQQKTLTQAEAGDIVALSRLDGVKTGDTLVVVDGSAVPDLPTAQQLEPVYSLAIAPRDRKDEVKLS
SAVSKLLEEDPSLSWEHRETTHEIILWGQGDIHLKIAIDRLGRKHKLPIKTHTPHVPYKESIRKSASSHGRYKHQTGGHG
QFGDVRLDIKPKARGEGFTFKETIVGGVVPRQYIPGVEMGVREFLQHGVLGFPIVDIDVTLTDGSYHSVDSSEQAFKQAA
RIAMQSGLPNCQPVLLEPIERVILSTPTKFTSQVLRLISNHRGQVLGYEGKSGWDSWDEISAYLPMAEMQSLIIELRSLT
QGVGFFIWRDDHLEEVPDKVAERVLARVETEF

Sequences:

>Translated_672_residues
MNSFRNIALVGPYSSGKTTLLESLLHVTEVTTRKGSVKEGNTVGDASAEARERQMSTEVTAASFEHGGLSFTFLDCPGSV
ELLQETLNCLVGVDAAVVVCEPEPQKVLTLAPLFQTLDEWEIPHLVFINKMDRANSPFSEVLDALKQVSSRPLVLHQYPI
GQNEDLQGFIDLVSEQAFHYHPDSPADPMPLPAELADQEKAAHTEMLEALADFDDHLLEELLEDIEPPQSEVLQDLKTEL
GADLIVPVFVGVAEAGYGVRPLLDALEKEAPEANDTAKSRELEPSSDRLVAQVLKNYFSPQGGKLSLVRVWQGTLTDGMI
LNQVRVGGIYRLLGQQQKTLTQAEAGDIVALSRLDGVKTGDTLVVVDGSAVPDLPTAQQLEPVYSLAIAPRDRKDEVKLS
SAVSKLLEEDPSLSWEHRETTHEIILWGQGDIHLKIAIDRLGRKHKLPIKTHTPHVPYKESIRKSASSHGRYKHQTGGHG
QFGDVRLDIKPKARGEGFTFKETIVGGVVPRQYIPGVEMGVREFLQHGVLGFPIVDIDVTLTDGSYHSVDSSEQAFKQAA
RIAMQSGLPNCQPVLLEPIERVILSTPTKFTSQVLRLISNHRGQVLGYEGKSGWDSWDEISAYLPMAEMQSLIIELRSLT
QGVGFFIWRDDHLEEVPDKVAERVLARVETEF
>Mature_672_residues
MNSFRNIALVGPYSSGKTTLLESLLHVTEVTTRKGSVKEGNTVGDASAEARERQMSTEVTAASFEHGGLSFTFLDCPGSV
ELLQETLNCLVGVDAAVVVCEPEPQKVLTLAPLFQTLDEWEIPHLVFINKMDRANSPFSEVLDALKQVSSRPLVLHQYPI
GQNEDLQGFIDLVSEQAFHYHPDSPADPMPLPAELADQEKAAHTEMLEALADFDDHLLEELLEDIEPPQSEVLQDLKTEL
GADLIVPVFVGVAEAGYGVRPLLDALEKEAPEANDTAKSRELEPSSDRLVAQVLKNYFSPQGGKLSLVRVWQGTLTDGMI
LNQVRVGGIYRLLGQQQKTLTQAEAGDIVALSRLDGVKTGDTLVVVDGSAVPDLPTAQQLEPVYSLAIAPRDRKDEVKLS
SAVSKLLEEDPSLSWEHRETTHEIILWGQGDIHLKIAIDRLGRKHKLPIKTHTPHVPYKESIRKSASSHGRYKHQTGGHG
QFGDVRLDIKPKARGEGFTFKETIVGGVVPRQYIPGVEMGVREFLQHGVLGFPIVDIDVTLTDGSYHSVDSSEQAFKQAA
RIAMQSGLPNCQPVLLEPIERVILSTPTKFTSQVLRLISNHRGQVLGYEGKSGWDSWDEISAYLPMAEMQSLIIELRSLT
QGVGFFIWRDDHLEEVPDKVAERVLARVETEF

Specific function: This Protein Promotes The GTP-Dependent Translocation Of The Nascent Protein Chain From The A-Site To The P-Site Of The Ribosome. [C]

COG id: COG0480

COG function: function code J; Translation elongation factors (GTPases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI18390331, Length=672, Percent_Identity=28.125, Blast_Score=247, Evalue=2e-65,
Organism=Homo sapiens, GI19923640, Length=693, Percent_Identity=26.1183261183261, Blast_Score=181, Evalue=1e-45,
Organism=Homo sapiens, GI25306287, Length=670, Percent_Identity=25.2238805970149, Blast_Score=157, Evalue=3e-38,
Organism=Homo sapiens, GI25306283, Length=382, Percent_Identity=28.0104712041885, Blast_Score=127, Evalue=3e-29,
Organism=Escherichia coli, GI1789738, Length=706, Percent_Identity=31.1614730878187, Blast_Score=311, Evalue=6e-86,
Organism=Escherichia coli, GI1790835, Length=393, Percent_Identity=23.6641221374046, Blast_Score=85, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17533571, Length=673, Percent_Identity=27.1916790490342, Blast_Score=251, Evalue=1e-66,
Organism=Caenorhabditis elegans, GI17556745, Length=689, Percent_Identity=22.7866473149492, Blast_Score=125, Evalue=6e-29,
Organism=Saccharomyces cerevisiae, GI6323098, Length=684, Percent_Identity=29.3859649122807, Blast_Score=263, Evalue=8e-71,
Organism=Saccharomyces cerevisiae, GI6322359, Length=524, Percent_Identity=26.1450381679389, Blast_Score=174, Evalue=6e-44,
Organism=Drosophila melanogaster, GI24582462, Length=671, Percent_Identity=29.2101341281669, Blast_Score=256, Evalue=3e-68,
Organism=Drosophila melanogaster, GI221458488, Length=723, Percent_Identity=22.9598893499308, Blast_Score=149, Evalue=5e-36,

Paralogues:

None

Copy number: 1080 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 7984 Molecules/Cell In: Growth Phase, Gl

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR005225
- InterPro:   IPR000640
- InterPro:   IPR005517
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00679 EFG_C; PF03764 EFG_IV; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: 3.6.5.3

Molecular weight: Translated: 74130; Mature: 74130

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: PS00398 RECOMBINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNSFRNIALVGPYSSGKTTLLESLLHVTEVTTRKGSVKEGNTVGDASAEARERQMSTEVT
CCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHH
AASFEHGGLSFTFLDCPGSVELLQETLNCLVGVDAAVVVCEPEPQKVLTLAPLFQTLDEW
HHEECCCCEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCCCCEEHHHHHHHHHHHC
EIPHLVFINKMDRANSPFSEVLDALKQVSSRPLVLHQYPIGQNEDLQGFIDLVSEQAFHY
CCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHEEE
HPDSPADPMPLPAELADQEKAAHTEMLEALADFDDHLLEELLEDIEPPQSEVLQDLKTEL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHH
GADLIVPVFVGVAEAGYGVRPLLDALEKEAPEANDTAKSRELEPSSDRLVAQVLKNYFSP
CCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHCC
QGGKLSLVRVWQGTLTDGMILNQVRVGGIYRLLGQQQKTLTQAEAGDIVALSRLDGVKTG
CCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCC
DTLVVVDGSAVPDLPTAQQLEPVYSLAIAPRDRKDEVKLSSAVSKLLEEDPSLSWEHRET
CEEEEECCCCCCCCCCHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
THEIILWGQGDIHLKIAIDRLGRKHKLPIKTHTPHVPYKESIRKSASSHGRYKHQTGGHG
CEEEEEECCCCEEEEEEEHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCC
QFGDVRLDIKPKARGEGFTFKETIVGGVVPRQYIPGVEMGVREFLQHGVLGFPIVDIDVT
CCCCEEEEECCCCCCCCCCHHHHHHHCCCCHHHCCCHHHHHHHHHHCCCCCCEEEEEEEE
LTDGSYHSVDSSEQAFKQAARIAMQSGLPNCQPVLLEPIERVILSTPTKFTSQVLRLISN
EECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHC
HRGQVLGYEGKSGWDSWDEISAYLPMAEMQSLIIELRSLTQGVGFFIWRDDHLEEVPDKV
CCCCEEEECCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHH
AERVLARVETEF
HHHHHHHHHCCC
>Mature Secondary Structure
MNSFRNIALVGPYSSGKTTLLESLLHVTEVTTRKGSVKEGNTVGDASAEARERQMSTEVT
CCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHH
AASFEHGGLSFTFLDCPGSVELLQETLNCLVGVDAAVVVCEPEPQKVLTLAPLFQTLDEW
HHEECCCCEEEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCCCCEEHHHHHHHHHHHC
EIPHLVFINKMDRANSPFSEVLDALKQVSSRPLVLHQYPIGQNEDLQGFIDLVSEQAFHY
CCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEECCCCCCCCHHHHHHHHHHHHEEE
HPDSPADPMPLPAELADQEKAAHTEMLEALADFDDHLLEELLEDIEPPQSEVLQDLKTEL
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHCCCCHHHHHHHHHHHH
GADLIVPVFVGVAEAGYGVRPLLDALEKEAPEANDTAKSRELEPSSDRLVAQVLKNYFSP
CCCHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHCCCCCCHHHHHHHHHHHHHCC
QGGKLSLVRVWQGTLTDGMILNQVRVGGIYRLLGQQQKTLTQAEAGDIVALSRLDGVKTG
CCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCC
DTLVVVDGSAVPDLPTAQQLEPVYSLAIAPRDRKDEVKLSSAVSKLLEEDPSLSWEHRET
CEEEEECCCCCCCCCCHHHHHHHHHHEECCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCC
THEIILWGQGDIHLKIAIDRLGRKHKLPIKTHTPHVPYKESIRKSASSHGRYKHQTGGHG
CEEEEEECCCCEEEEEEEHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCC
QFGDVRLDIKPKARGEGFTFKETIVGGVVPRQYIPGVEMGVREFLQHGVLGFPIVDIDVT
CCCCEEEEECCCCCCCCCCHHHHHHHCCCCHHHCCCHHHHHHHHHHCCCCCCEEEEEEEE
LTDGSYHSVDSSEQAFKQAARIAMQSGLPNCQPVLLEPIERVILSTPTKFTSQVLRLISN
EECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHC
HRGQVLGYEGKSGWDSWDEISAYLPMAEMQSLIIELRSLTQGVGFFIWRDDHLEEVPDKV
CCCCEEEECCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHCCCCEEEECCCHHHHHHHHH
AERVLARVETEF
HHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GTP; H2O

Specific reaction: GTP + H2O = GDP + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231 [H]