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The map label for this gene is pqqL [C]

Identifier: 158333791

GI number: 158333791

Start: 586965

End: 588221

Strand: Direct

Name: pqqL [C]

Synonym: AM1_0599

Alternate gene names: 158333791

Gene position: 586965-588221 (Clockwise)

Preceding gene: 158333790

Following gene: 158333793

Centisome position: 9.03

GC content: 51.63

Gene sequence:

>1257_bases
ATGGCAACTCCCCCATTACTGCATCCCTCCTGCCACCGTACCCCTGAAGGGTTAACGGTTATTGCCGAACATCTACCCGT
GGATGCGGTCAACTTTAGTTTGTGGGTCAATGCGGGGTCGGCGGTGGAGGACGACGCCATCAATGGGATGGCCCATTTTT
TAGAGCATATGGTGTTTAAGGGGACGGAGCAGCTTCCCGAAGGTGAGTTTGAGCGCCAGGTGGAAGCCCGAGGCGGCGTC
ACCAATGCGGTCACCAGCCAGGACTATACCTGTTTTTACGTCACCGTTGCTCCCCAAGACTTTACTACGATCGCTCCTTT
GCAAATCGATCTAACCCTCAATGCTCGCCTTGATGTCGAGAGCTTCGAGCGGGAACGACTTGTTGTCTTAGAAGAAATTC
GACGGTCTGATGATAATGTTCGCCGTCGGTTATTTCGCCAAGCCATGACCTTGGGATATGCCCAATTACCCTATCGGCGA
CCGGTTCTGGGTCCTGCTGAAGTGATCCAATCCCTGGCTCCAGAGCAAATGTACGACCATCATCGGTCCTGGTATCATCC
CGAAAATATCACTGCCGTTGTGGTGGGGAATTTACCCGTAGAGCAGATGGTTGAAACCGTAGTTCAAGAATTTGCCACCC
CTTCTCGCCCTCCTCCCCTGGCTCCAGTCCAATCCCTCGAACCGCCTTTTGTTGAAATTACTCGGCAAACGGTCGTTGAC
CCTAAACTGACTCAAGCTCGTTTAGTGTTGCTATGGCGAGTCCCAGGTATTCAACAGCTCTCCCAAACCTATACCTTAGA
TGTCCTAGCCAGGATCTTAGGGGGTGGACGAAACTCTCGCTTAGTCAAATCCTTGCGGGAAGAGAAACAGTGGGTTGAGC
GTATTTCTGTGAGTAACCTGACTCAGGTGTGGCAAGGATTATTTTGGATCTCCGCCCAGGTGCCACCAGAGAACTTGGAA
CGGGTAGAAGCGGAAATTGTCAATCATTTGCGTCAGCTCCAAGATGAAGCTTTGCCTGGATCAGAACTGGCTCGACGACA
ACGACAACTGGTCAATCAGCATTTATTTGGTACTGAAAGCCCGTCTAGTCGAGCAGGTCTTTATGGATACCACCATGCGA
TCGCCCATAACCTAGAGGCTGGTCTTCTGTATCCACAACATATTCAGCAGCTGACCCCAGCTGATTTGCAGCAGGCTGCC
CAGACCTACCTCTCCACGACTGCTTACCGGGTGTTAAAGGTACTGCCAAAGTCTTAA

Upstream 100 bases:

>100_bases
ATTTACTAGGTCTATTACGAAATCACGCCCTCGTGCTCGGGGACTTCGGTGCGATTGTCAAAAGCTAGAATATAGAAGAA
CGCACAGTGCCTTTGCCTCC

Downstream 100 bases:

>100_bases
TCCCTAATGCCGACCTTAACTGACCGATAACTGTTTCAAGAGGGTATCCACTTTTTTGACCCCATCGGCTTGGCGCTGAA
GCTGGTATAGCTGGCGAGCC

Product: M16 family peptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 418; Mature: 417

Protein sequence:

>418_residues
MATPPLLHPSCHRTPEGLTVIAEHLPVDAVNFSLWVNAGSAVEDDAINGMAHFLEHMVFKGTEQLPEGEFERQVEARGGV
TNAVTSQDYTCFYVTVAPQDFTTIAPLQIDLTLNARLDVESFERERLVVLEEIRRSDDNVRRRLFRQAMTLGYAQLPYRR
PVLGPAEVIQSLAPEQMYDHHRSWYHPENITAVVVGNLPVEQMVETVVQEFATPSRPPPLAPVQSLEPPFVEITRQTVVD
PKLTQARLVLLWRVPGIQQLSQTYTLDVLARILGGGRNSRLVKSLREEKQWVERISVSNLTQVWQGLFWISAQVPPENLE
RVEAEIVNHLRQLQDEALPGSELARRQRQLVNQHLFGTESPSSRAGLYGYHHAIAHNLEAGLLYPQHIQQLTPADLQQAA
QTYLSTTAYRVLKVLPKS

Sequences:

>Translated_418_residues
MATPPLLHPSCHRTPEGLTVIAEHLPVDAVNFSLWVNAGSAVEDDAINGMAHFLEHMVFKGTEQLPEGEFERQVEARGGV
TNAVTSQDYTCFYVTVAPQDFTTIAPLQIDLTLNARLDVESFERERLVVLEEIRRSDDNVRRRLFRQAMTLGYAQLPYRR
PVLGPAEVIQSLAPEQMYDHHRSWYHPENITAVVVGNLPVEQMVETVVQEFATPSRPPPLAPVQSLEPPFVEITRQTVVD
PKLTQARLVLLWRVPGIQQLSQTYTLDVLARILGGGRNSRLVKSLREEKQWVERISVSNLTQVWQGLFWISAQVPPENLE
RVEAEIVNHLRQLQDEALPGSELARRQRQLVNQHLFGTESPSSRAGLYGYHHAIAHNLEAGLLYPQHIQQLTPADLQQAA
QTYLSTTAYRVLKVLPKS
>Mature_417_residues
ATPPLLHPSCHRTPEGLTVIAEHLPVDAVNFSLWVNAGSAVEDDAINGMAHFLEHMVFKGTEQLPEGEFERQVEARGGVT
NAVTSQDYTCFYVTVAPQDFTTIAPLQIDLTLNARLDVESFERERLVVLEEIRRSDDNVRRRLFRQAMTLGYAQLPYRRP
VLGPAEVIQSLAPEQMYDHHRSWYHPENITAVVVGNLPVEQMVETVVQEFATPSRPPPLAPVQSLEPPFVEITRQTVVDP
KLTQARLVLLWRVPGIQQLSQTYTLDVLARILGGGRNSRLVKSLREEKQWVERISVSNLTQVWQGLFWISAQVPPENLER
VEAEIVNHLRQLQDEALPGSELARRQRQLVNQHLFGTESPSSRAGLYGYHHAIAHNLEAGLLYPQHIQQLTPADLQQAAQ
TYLSTTAYRVLKVLPKS

Specific function: Unknown

COG id: COG0612

COG function: function code R; Predicted Zn-dependent peptidases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M16 family [H]

Homologues:

Organism=Homo sapiens, GI94538354, Length=268, Percent_Identity=28.3582089552239, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI46593007, Length=189, Percent_Identity=26.4550264550265, Blast_Score=99, Evalue=6e-21,
Organism=Homo sapiens, GI155969707, Length=323, Percent_Identity=23.2198142414861, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI24308013, Length=186, Percent_Identity=26.8817204301075, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI1787770, Length=243, Percent_Identity=27.1604938271605, Blast_Score=79, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17553678, Length=182, Percent_Identity=28.021978021978, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI71999683, Length=198, Percent_Identity=26.7676767676768, Blast_Score=89, Evalue=4e-18,
Organism=Saccharomyces cerevisiae, GI6323192, Length=351, Percent_Identity=24.2165242165242, Blast_Score=102, Evalue=9e-23,
Organism=Saccharomyces cerevisiae, GI6321813, Length=372, Percent_Identity=23.1182795698925, Blast_Score=70, Evalue=7e-13,
Organism=Saccharomyces cerevisiae, GI6323421, Length=285, Percent_Identity=21.0526315789474, Blast_Score=65, Evalue=2e-11,
Organism=Drosophila melanogaster, GI21357875, Length=200, Percent_Identity=29.5, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24646943, Length=200, Percent_Identity=29.5, Blast_Score=112, Evalue=4e-25,
Organism=Drosophila melanogaster, GI24641429, Length=268, Percent_Identity=24.2537313432836, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24667786, Length=138, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011249
- InterPro:   IPR011237
- InterPro:   IPR011765
- InterPro:   IPR001431
- InterPro:   IPR007863 [H]

Pfam domain/function: PF00675 Peptidase_M16; PF05193 Peptidase_M16_C [H]

EC number: 3.4.99.- [C]

Molecular weight: Translated: 47205; Mature: 47074

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS00143 INSULINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATPPLLHPSCHRTPEGLTVIAEHLPVDAVNFSLWVNAGSAVEDDAINGMAHFLEHMVFK
CCCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHC
GTEQLPEGEFERQVEARGGVTNAVTSQDYTCFYVTVAPQDFTTIAPLQIDLTLNARLDVE
CCCCCCCCHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCEECCEEEEEEECCEECHH
SFERERLVVLEEIRRSDDNVRRRLFRQAMTLGYAQLPYRRPVLGPAEVIQSLAPEQMYDH
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCHHHHHHH
HRSWYHPENITAVVVGNLPVEQMVETVVQEFATPSRPPPLAPVQSLEPPFVEITRQTVVD
HCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCHHHHHHHHHCC
PKLTQARLVLLWRVPGIQQLSQTYTLDVLARILGGGRNSRLVKSLREEKQWVERISVSNL
CCHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
TQVWQGLFWISAQVPPENLERVEAEIVNHLRQLQDEALPGSELARRQRQLVNQHLFGTES
HHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC
PSSRAGLYGYHHAIAHNLEAGLLYPQHIQQLTPADLQQAAQTYLSTTAYRVLKVLPKS
CCCCCCCHHHHHHHHHCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
ATPPLLHPSCHRTPEGLTVIAEHLPVDAVNFSLWVNAGSAVEDDAINGMAHFLEHMVFK
CCCCCCCCCCCCCCCCHHHHHHHCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHC
GTEQLPEGEFERQVEARGGVTNAVTSQDYTCFYVTVAPQDFTTIAPLQIDLTLNARLDVE
CCCCCCCCHHHHHHHHCCCCCCCCCCCCCEEEEEEECCCCCCEECCEEEEEEECCEECHH
SFERERLVVLEEIRRSDDNVRRRLFRQAMTLGYAQLPYRRPVLGPAEVIQSLAPEQMYDH
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCHHHHHHH
HRSWYHPENITAVVVGNLPVEQMVETVVQEFATPSRPPPLAPVQSLEPPFVEITRQTVVD
HCCCCCCCCCEEEEECCCCHHHHHHHHHHHHCCCCCCCCCCCHHCCCCCHHHHHHHHHCC
PKLTQARLVLLWRVPGIQQLSQTYTLDVLARILGGGRNSRLVKSLREEKQWVERISVSNL
CCHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHH
TQVWQGLFWISAQVPPENLERVEAEIVNHLRQLQDEALPGSELARRQRQLVNQHLFGTES
HHHHHHHEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCC
PSSRAGLYGYHHAIAHNLEAGLLYPQHIQQLTPADLQQAAQTYLSTTAYRVLKVLPKS
CCCCCCCHHHHHHHHHCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: Zn [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Endopeptidases of unknown catalytic mechanism [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11234002 [H]