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The map label for this gene is adrA [H]

Identifier: 158333739

GI number: 158333739

Start: 529233

End: 530564

Strand: Reverse

Name: adrA [H]

Synonym: AM1_0547

Alternate gene names: 158333739

Gene position: 530564-529233 (Counterclockwise)

Preceding gene: 158333740

Following gene: 158333737

Centisome position: 8.16

GC content: 48.5

Gene sequence:

>1332_bases
ATGCCCTTTTGGTCCACGCCTAAAACCTCTCTAAACCAGCGTCTTCGGCTGGGTTTAGGGACCATGCTTGTGCCCTTACT
GATGTTAGCGGCAGGGGCAGTTATTTCCTTTGAAGGGGCATTGGATAGCTTTCGTAAGCACGATAATGTAGGTCGAGAAG
CCTTGTTCCCCCTAGCCCATGTTGAGGGGTTACTTCTAGATTTAAATGTGGTGGCCTCACCGGTGGAACCATCTCGCTCC
ATAACGTGGAGTGAGTATCAGCTTAAAAGTCAAGCGATTGAAGCGAGTTTGGCCAGGCTCCTAGAATTCTCCCACCAGGA
TCCACACAAATTTAATTCTGTACAGGAAATACAACGAAAATGGCATCGAATTTCCCAGCTGTGTCAACAAATCTTGGATC
CTTCGGTTGCTCAATCGGGAAAGGGCTTGTCAGAACCTGCCAGAGTTGAGCTGCAAGAACAGCTGAAAATGATTTTGCAG
AATGTCCAACAACTGAATTATCGGTTAATTGCATTTCAAAATGATGCCAATGCCAACCACGCAGAAGCCGTGCGCAAAGA
AGTTAGACAGATGATCGCCATGATTTGCGGTTTGGCTTTGATGCTAGCAGTCGTGTTTGCCTATGGACTCACTCGGTCCA
TTACAGTCCCCCTTCAATCTTTGGAGGACGGGGTTGAGAAATTAGGCAAGGGAGATTTGAGCCATCGGATTTCTTTGGCC
GCTGACGCTGAATTTAGTCATTTGGCCGCAACCTTTAACTTAATGGCGACCAAGCTGGAGCAAAGCCAACAAGACTTATA
CCGTTTAGCAACATTGGATGGGCTAACGGAAGTTTACAATCGGCGGGAATTTAATCGCTGGTTGAGGGTGGAAGTCGAGA
AATCCCAGCGCAATACCGATCAAGTTTCGCTGATCATGGTGGATATTGATCATTTCAAGCAGCTCAATGATACCTATGGC
CATCAGGCCGGAGATTTGGCCCTTTGTGAGGTGGCTCAACTTCTACAGCGCGAAGTGCGACCTGGGGATATTGTCTGCCG
GTATGGTGGCGAAGAATTTGCGGTCATTCTGCCCAAGACCAATCATGATGATAGTGTTGCGATCGCAGATCGGATCCGTC
TAGCCATTGCCGAGGAAGCGATTATTCTACCCTCCTTGCAGCAAATAGAGATGACGGCCAGCCTAGGGGTTGCCACCTTC
CCTGGTGATGCCCAAACCAAAGAGCACCTGATCAAACAAGCCGATCAGGCGCTCTATGGTGCTAAGACTTCAGGTCGAAA
TCGAGTCCACCAGGCTCAACAAAATGTTGTCGAAAACCAAGTGGTGGTCTAA

Upstream 100 bases:

>100_bases
TTGCTCGTCCTCTTCAACCGGAGGCAGCCCAACAGGTTATTGCTACCCTGTCTAGTCCCATGAGCTTGTCTCTACCGATT
GCAGAATAAGCAGTACTTCC

Downstream 100 bases:

>100_bases
CTACTTCTTATCAAACAAGGCCCCTAGAGTATCAGGATTCATCATATTGCACTCCATCAGCTTGAGGGCCAAGGCTGTGC
CAACACGATTGGCTACAACT

Product: diguanylate cyclase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 442

Protein sequence:

>443_residues
MPFWSTPKTSLNQRLRLGLGTMLVPLLMLAAGAVISFEGALDSFRKHDNVGREALFPLAHVEGLLLDLNVVASPVEPSRS
ITWSEYQLKSQAIEASLARLLEFSHQDPHKFNSVQEIQRKWHRISQLCQQILDPSVAQSGKGLSEPARVELQEQLKMILQ
NVQQLNYRLIAFQNDANANHAEAVRKEVRQMIAMICGLALMLAVVFAYGLTRSITVPLQSLEDGVEKLGKGDLSHRISLA
ADAEFSHLAATFNLMATKLEQSQQDLYRLATLDGLTEVYNRREFNRWLRVEVEKSQRNTDQVSLIMVDIDHFKQLNDTYG
HQAGDLALCEVAQLLQREVRPGDIVCRYGGEEFAVILPKTNHDDSVAIADRIRLAIAEEAIILPSLQQIEMTASLGVATF
PGDAQTKEHLIKQADQALYGAKTSGRNRVHQAQQNVVENQVVV

Sequences:

>Translated_443_residues
MPFWSTPKTSLNQRLRLGLGTMLVPLLMLAAGAVISFEGALDSFRKHDNVGREALFPLAHVEGLLLDLNVVASPVEPSRS
ITWSEYQLKSQAIEASLARLLEFSHQDPHKFNSVQEIQRKWHRISQLCQQILDPSVAQSGKGLSEPARVELQEQLKMILQ
NVQQLNYRLIAFQNDANANHAEAVRKEVRQMIAMICGLALMLAVVFAYGLTRSITVPLQSLEDGVEKLGKGDLSHRISLA
ADAEFSHLAATFNLMATKLEQSQQDLYRLATLDGLTEVYNRREFNRWLRVEVEKSQRNTDQVSLIMVDIDHFKQLNDTYG
HQAGDLALCEVAQLLQREVRPGDIVCRYGGEEFAVILPKTNHDDSVAIADRIRLAIAEEAIILPSLQQIEMTASLGVATF
PGDAQTKEHLIKQADQALYGAKTSGRNRVHQAQQNVVENQVVV
>Mature_442_residues
PFWSTPKTSLNQRLRLGLGTMLVPLLMLAAGAVISFEGALDSFRKHDNVGREALFPLAHVEGLLLDLNVVASPVEPSRSI
TWSEYQLKSQAIEASLARLLEFSHQDPHKFNSVQEIQRKWHRISQLCQQILDPSVAQSGKGLSEPARVELQEQLKMILQN
VQQLNYRLIAFQNDANANHAEAVRKEVRQMIAMICGLALMLAVVFAYGLTRSITVPLQSLEDGVEKLGKGDLSHRISLAA
DAEFSHLAATFNLMATKLEQSQQDLYRLATLDGLTEVYNRREFNRWLRVEVEKSQRNTDQVSLIMVDIDHFKQLNDTYGH
QAGDLALCEVAQLLQREVRPGDIVCRYGGEEFAVILPKTNHDDSVAIADRIRLAIAEEAIILPSLQQIEMTASLGVATFP
GDAQTKEHLIKQADQALYGAKTSGRNRVHQAQQNVVENQVVV

Specific function: Unknown

COG id: COG2199

COG function: function code T; FOG: GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1786584, Length=177, Percent_Identity=38.9830508474576, Blast_Score=131, Evalue=8e-32,
Organism=Escherichia coli, GI87081881, Length=208, Percent_Identity=36.0576923076923, Blast_Score=118, Evalue=1e-27,
Organism=Escherichia coli, GI145693134, Length=158, Percent_Identity=37.3417721518987, Blast_Score=115, Evalue=5e-27,
Organism=Escherichia coli, GI87082007, Length=177, Percent_Identity=39.5480225988701, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1787262, Length=164, Percent_Identity=37.1951219512195, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI1788381, Length=211, Percent_Identity=30.3317535545024, Blast_Score=98, Evalue=8e-22,
Organism=Escherichia coli, GI1787802, Length=165, Percent_Identity=35.1515151515151, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788085, Length=167, Percent_Identity=32.9341317365269, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1787816, Length=175, Percent_Identity=33.7142857142857, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1787056, Length=166, Percent_Identity=32.5301204819277, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081974, Length=165, Percent_Identity=30.9090909090909, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1787541, Length=173, Percent_Identity=29.4797687861272, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI1788956, Length=245, Percent_Identity=28.9795918367347, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI87081977, Length=150, Percent_Identity=28.6666666666667, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI87081921, Length=181, Percent_Identity=23.7569060773481, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR007894 [H]

Pfam domain/function: PF00990 GGDEF; PF05230 MASE2 [H]

EC number: NA

Molecular weight: Translated: 49484; Mature: 49353

Theoretical pI: Translated: 6.33; Mature: 6.33

Prosite motif: PS50885 HAMP ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPFWSTPKTSLNQRLRLGLGTMLVPLLMLAAGAVISFEGALDSFRKHDNVGREALFPLAH
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHEEEHHHHHHHHHHCCCCHHHHHHHHH
VEGLLLDLNVVASPVEPSRSITWSEYQLKSQAIEASLARLLEFSHQDPHKFNSVQEIQRK
HHHHHEEHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
WHRISQLCQQILDPSVAQSGKGLSEPARVELQEQLKMILQNVQQLNYRLIAFQNDANANH
HHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCH
AEAVRKEVRQMIAMICGLALMLAVVFAYGLTRSITVPLQSLEDGVEKLGKGDLSHRISLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEHHHHHHHHHHHHHCCCCHHHEEEEE
ADAEFSHLAATFNLMATKLEQSQQDLYRLATLDGLTEVYNRREFNRWLRVEVEKSQRNTD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHHCCCCC
QVSLIMVDIDHFKQLNDTYGHQAGDLALCEVAQLLQREVRPGDIVCRYGGEEFAVILPKT
CEEEEEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCEEEEEECCC
NHDDSVAIADRIRLAIAEEAIILPSLQQIEMTASLGVATFPGDAQTKEHLIKQADQALYG
CCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHC
AKTSGRNRVHQAQQNVVENQVVV
CCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PFWSTPKTSLNQRLRLGLGTMLVPLLMLAAGAVISFEGALDSFRKHDNVGREALFPLAH
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCHHEEEHHHHHHHHHHCCCCHHHHHHHHH
VEGLLLDLNVVASPVEPSRSITWSEYQLKSQAIEASLARLLEFSHQDPHKFNSVQEIQRK
HHHHHEEHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
WHRISQLCQQILDPSVAQSGKGLSEPARVELQEQLKMILQNVQQLNYRLIAFQNDANANH
HHHHHHHHHHHHCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEEEEECCCCCCH
AEAVRKEVRQMIAMICGLALMLAVVFAYGLTRSITVPLQSLEDGVEKLGKGDLSHRISLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHEEHHHHHHHHHHHHHCCCCHHHEEEEE
ADAEFSHLAATFNLMATKLEQSQQDLYRLATLDGLTEVYNRREFNRWLRVEVEKSQRNTD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEHHHCCCCC
QVSLIMVDIDHFKQLNDTYGHQAGDLALCEVAQLLQREVRPGDIVCRYGGEEFAVILPKT
CEEEEEEEHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCEEEEEECCC
NHDDSVAIADRIRLAIAEEAIILPSLQQIEMTASLGVATFPGDAQTKEHLIKQADQALYG
CCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCEECCCCCHHHHHHHHHHHHHHHC
AKTSGRNRVHQAQQNVVENQVVV
CCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]