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The map label for this gene is pilC [H]

Identifier: 158333616

GI number: 158333616

Start: 390490

End: 391710

Strand: Reverse

Name: pilC [H]

Synonym: AM1_0417

Alternate gene names: 158333616

Gene position: 391710-390490 (Counterclockwise)

Preceding gene: 158333617

Following gene: 158333615

Centisome position: 6.02

GC content: 43.24

Gene sequence:

>1221_bases
ATGCCAACTTACGTCGTCCGTGCGCGAGACTCTCAAGGAAAATCAAGCCAAAAAAGGGTAAACGCAACCTCTCAAAAAGA
AGCTCGTTCTAATATCCAACGCCAAGGGCTACAGATCCTTGATATAAAGGAATCTCAAGGCTTCAGCATGAATGCTGAGC
TGGATCTGAGTTTTCTTCAGTCCATCACTGTTAAAGATAAAGCTTTGTTCTCGAGACAGTTTTCAGCTCTAGTCAATGCC
GGGGTTGCATTGGTAAGGGGCTTGGGAGTTATGTCTGAACAGTGTAAGAATCCTAAGCTTAAAAAGGCACTTCTAGATGT
CAATGCTGCTGTCCAACAAGGCGTTAGCTTATCAGATGCTATGAGGGGCCACCCTGCTGCTTTCGATCAGCTGTATGTTG
CCATGATTCAAGCAGGTGAAACAGGTGGTGTTTTGGATGAGGTTCTCAATCGTCTAGCCACTTTGCTGGAAGATCAAGCG
CGTTTGAAAAACCAGATTCGATCAGCGCTAGCATATCCAGTTGTCGTTGGTTTTATCGCTGTTTCAATCTTTTTGGGAAT
GGTTATTTTCCTTATCCCAGTATTTGACGGCATATTTAGCCAATTAGGTGGTGACTTACCTGCATTTACTCAATTTATGG
TGAATCTCAGTGAATTTCTGAGAACACCGATTTATGGGATTTCAGCTGCCATTGTAGTTTTTGGATCCACATTTGCCCTT
CGGCAGTACTATCGAACCCGAGCAGGCAGAGAAACTATTGATCGAATCATGCTTAAGTTGCCTCTGTTTGGTGATCTGAT
TCAAAAGACGGCTGTGGCTAGATTTTGTCGAACTTTTGGGTCACTTTCTCGTTCGGGTGTGCCTATTCTCTATTCTCTCG
AAATTGTTCGTGATACTGCAGGAAACCAGGTTGTATCTAACGCTATTGATGAAGCTCGACGAGAAATTCAAGGGGGTGGC
ATGTTGAGCTTAGCGTTGCAAAAAGAAAAAGTATTTCCTCTCCTAGCGACTCAAATGATCAATGTTGGGGAAGAAACAGG
AGAGATTGACAAGATGCTGATGAAGGTTGCTGATTTTTATGAAGATGAAGTCGAACAGGCGGTTAAAGCCATGACTAGTG
TGATGGAACCCTTGATGATCGTTGTTTTAGGAGGTATGGTTGGTTCCATTCTTGTGGCTATGTATTTGCCTATGTTCAAG
ATCTTCGATCTAATCGGTTAA

Upstream 100 bases:

>100_bases
GGGGAATCAACGTGGCTCTGGTGCCGCACCCTATCGGCGATAAGCATTGAGTATAAACCTAACATTCGTTCTTTCTTCAT
TTACTGCTGAGAATTGAGTT

Downstream 100 bases:

>100_bases
TCAAGGGTTATTCAGTGGTTTACTCAGTTTAAGTGTGATTTACGCTAAATTTCGCTAGCTCCTAATACATATTGTAAGCA
AGCTCTATCGACTAAGAGAT

Product: type II secretion system domain-containing protein/ pilin biogenesis protein PilC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 406; Mature: 405

Protein sequence:

>406_residues
MPTYVVRARDSQGKSSQKRVNATSQKEARSNIQRQGLQILDIKESQGFSMNAELDLSFLQSITVKDKALFSRQFSALVNA
GVALVRGLGVMSEQCKNPKLKKALLDVNAAVQQGVSLSDAMRGHPAAFDQLYVAMIQAGETGGVLDEVLNRLATLLEDQA
RLKNQIRSALAYPVVVGFIAVSIFLGMVIFLIPVFDGIFSQLGGDLPAFTQFMVNLSEFLRTPIYGISAAIVVFGSTFAL
RQYYRTRAGRETIDRIMLKLPLFGDLIQKTAVARFCRTFGSLSRSGVPILYSLEIVRDTAGNQVVSNAIDEARREIQGGG
MLSLALQKEKVFPLLATQMINVGEETGEIDKMLMKVADFYEDEVEQAVKAMTSVMEPLMIVVLGGMVGSILVAMYLPMFK
IFDLIG

Sequences:

>Translated_406_residues
MPTYVVRARDSQGKSSQKRVNATSQKEARSNIQRQGLQILDIKESQGFSMNAELDLSFLQSITVKDKALFSRQFSALVNA
GVALVRGLGVMSEQCKNPKLKKALLDVNAAVQQGVSLSDAMRGHPAAFDQLYVAMIQAGETGGVLDEVLNRLATLLEDQA
RLKNQIRSALAYPVVVGFIAVSIFLGMVIFLIPVFDGIFSQLGGDLPAFTQFMVNLSEFLRTPIYGISAAIVVFGSTFAL
RQYYRTRAGRETIDRIMLKLPLFGDLIQKTAVARFCRTFGSLSRSGVPILYSLEIVRDTAGNQVVSNAIDEARREIQGGG
MLSLALQKEKVFPLLATQMINVGEETGEIDKMLMKVADFYEDEVEQAVKAMTSVMEPLMIVVLGGMVGSILVAMYLPMFK
IFDLIG
>Mature_405_residues
PTYVVRARDSQGKSSQKRVNATSQKEARSNIQRQGLQILDIKESQGFSMNAELDLSFLQSITVKDKALFSRQFSALVNAG
VALVRGLGVMSEQCKNPKLKKALLDVNAAVQQGVSLSDAMRGHPAAFDQLYVAMIQAGETGGVLDEVLNRLATLLEDQAR
LKNQIRSALAYPVVVGFIAVSIFLGMVIFLIPVFDGIFSQLGGDLPAFTQFMVNLSEFLRTPIYGISAAIVVFGSTFALR
QYYRTRAGRETIDRIMLKLPLFGDLIQKTAVARFCRTFGSLSRSGVPILYSLEIVRDTAGNQVVSNAIDEARREIQGGGM
LSLALQKEKVFPLLATQMINVGEETGEIDKMLMKVADFYEDEVEQAVKAMTSVMEPLMIVVLGGMVGSILVAMYLPMFKI
FDLIG

Specific function: Involved in the translocation of the type IV pilin (pilA) [H]

COG id: COG1459

COG function: function code NU; Type II secretory pathway, component PulF

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP F family [H]

Homologues:

Organism=Escherichia coli, GI1789724, Length=404, Percent_Identity=25.4950495049505, Blast_Score=171, Evalue=6e-44,
Organism=Escherichia coli, GI1786295, Length=334, Percent_Identity=28.1437125748503, Blast_Score=152, Evalue=5e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003004
- InterPro:   IPR018076
- InterPro:   IPR001992 [H]

Pfam domain/function: PF00482 GSPII_F [H]

EC number: NA

Molecular weight: Translated: 44504; Mature: 44373

Theoretical pI: Translated: 8.94; Mature: 8.94

Prosite motif: PS00874 T2SP_F

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTYVVRARDSQGKSSQKRVNATSQKEARSNIQRQGLQILDIKESQGFSMNAELDLSFLQ
CCCEEEEECCCCCCCHHHHHCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHH
SITVKDKALFSRQFSALVNAGVALVRGLGVMSEQCKNPKLKKALLDVNAAVQQGVSLSDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHH
MRGHPAAFDQLYVAMIQAGETGGVLDEVLNRLATLLEDQARLKNQIRSALAYPVVVGFIA
HCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSIFLGMVIFLIPVFDGIFSQLGGDLPAFTQFMVNLSEFLRTPIYGISAAIVVFGSTFAL
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
RQYYRTRAGRETIDRIMLKLPLFGDLIQKTAVARFCRTFGSLSRSGVPILYSLEIVRDTA
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHCC
GNQVVSNAIDEARREIQGGGMLSLALQKEKVFPLLATQMINVGEETGEIDKMLMKVADFY
CHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
EDEVEQAVKAMTSVMEPLMIVVLGGMVGSILVAMYLPMFKIFDLIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PTYVVRARDSQGKSSQKRVNATSQKEARSNIQRQGLQILDIKESQGFSMNAELDLSFLQ
CCEEEEECCCCCCCHHHHHCCHHHHHHHHHHHHCCCEEEEECCCCCCCCCCHHHHHHHH
SITVKDKALFSRQFSALVNAGVALVRGLGVMSEQCKNPKLKKALLDVNAAVQQGVSLSDA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHH
MRGHPAAFDQLYVAMIQAGETGGVLDEVLNRLATLLEDQARLKNQIRSALAYPVVVGFIA
HCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VSIFLGMVIFLIPVFDGIFSQLGGDLPAFTQFMVNLSEFLRTPIYGISAAIVVFGSTFAL
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
RQYYRTRAGRETIDRIMLKLPLFGDLIQKTAVARFCRTFGSLSRSGVPILYSLEIVRDTA
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHHCC
GNQVVSNAIDEARREIQGGGMLSLALQKEKVFPLLATQMINVGEETGEIDKMLMKVADFY
CHHHHHHHHHHHHHHHCCCCEEEEEHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
EDEVEQAVKAMTSVMEPLMIVVLGGMVGSILVAMYLPMFKIFDLIG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1971619; 10984043 [H]