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The map label for this gene is wzc [H]

Identifier: 158333590

GI number: 158333590

Start: 362101

End: 364233

Strand: Reverse

Name: wzc [H]

Synonym: AM1_0391

Alternate gene names: 158333590

Gene position: 364233-362101 (Counterclockwise)

Preceding gene: 158333594

Following gene: 158333589

Centisome position: 5.6

GC content: 38.58

Gene sequence:

>2133_bases
TTGTCAAATTATTGGTTGATGCTGAAGAGACGAGGTTTGCCTGCGGGATTTACTTTTTTGACCGTTTTATCACTTGCGTT
GCTGCAAGCTTTTCAAGAGAAACCTATTTATGAAGCGGTTGGGCAACTGAAATTTGAGGAAAGTCAACGGAGCTCAAAAT
TAATTGGTCTAGATTCTGCAGTCGATGATGAAAGTCGGCAACAATCTAGTTTACGTTGGCAAAGGTCACTAGACACTGAA
ATCCTTACTATGAAAAGTCCCAGACGGCTTAGTATGCTTGCTTTGGCCATTGAAAGTCAAGGTCTGTTCTCCCGGCCTAG
CGTAGAGCAAATTAAATCTGGGTTAGATATTTCTCAATTTGATGAGACTAACGTAGTCCAGATTCGATTCAAAAGTTATA
ATCGCGAATTTCCCAAAAATATTGTTAACTTGCTGATGCAGCAATATGTTGACAATACTCCTAAGTCGAAACAAGCATCT
ACCCAATCAGCAATTTCGTTTATTGAAAAACAACTGCCTCAAGTTAAGCAGCGCGTTAACTCTGCAGAAACAGCATTGCG
CAAATTTAAGGAAACCTATCAGATTGCCGATCTAGAGATTGCTAAATCTGCTAACGCAACTAACCTTTCTCAACTCCAGA
CAGCCCTAGATGAAATCGATAGGGAGTTAGTAGAGGTGCAAACTCAGCAGCTAAGTCTGCAAAATATGCTAAAAGTGAAT
CCACAGCAAGCAATATTAGGAATTTCAACTGCCCACAAGAATATATCAACTAGCCTTGAGGAGATAGACAAAGACCTAGC
GGAAGCAAAATCAAACTTTAGAGAAGATCATCCCGCTGTTTTGGAATTATTGGAGAGGCAGGCTCAATTAAAGCAATTGC
TAAGCCAAAAAATAGAAAAATTTGCTCAGTCTGATGCCCAGTTAAATTTTGACTCGAATCAAGAAGATGATTTGCGCTCC
CAACTTATCCAGCTGGATATTAGGCGTAATGGGTTGTCTAAGCAACAGTTGAAATTGAGACAACAATTGTCTAGTTATCG
TCAGCAAGCACGAAATTTGCCTCAATTAGAACAACGTCAGAATGAGCTAGAGAGAACTGCAAAAGCATCTGCTTCTACCT
ATCGAAATTTGCTTGAACAAATTCAAGAGTTGAAAGTTACTGAAAATCAGTCTCCCTTGACTGTGAGTATTTTAGAAAGT
GCGACTGATCCGGAACCATCTAAAACCACTTTTATCTCAGCAGCGATGCGAGGCGGATTAGCAGGTATACTTTTGGCATC
AGGGGTAGTCTATGTTCTAGAACGAATAGATCGAAAGCTAAAATCCAAAGATGAAATTAGACAAGTTTACCCTTATCGAG
TGTTAGGTGAAATTCCTTTGTTTGACGAAAGTGAAGCGGAATCCCTAAAACTACCAACTTTGTCCGACCCTGCTTCTCAC
TTAAGTGAAGCTTACAGAATGCTCCAATCTAGCTTGAAATTCCATGGTTTGGAACATTCTCCTAGAGTATTAATGATGAC
TAGTGCCATAAACCAAGAGGGTAAAAGTACGACTTGTGCTAATTTAGCGGTTTCTTTGGCTCAAATGAACCATCGAGTTT
TATTGATTGATGCTGATATTCGCTTAGCCTCTCAACATCAAATCTGGGAATTAGGGAATCAAGAAGGCTTAACGCATATA
TTATTGAATAAACATTTTAATTATCATCAAGAATTGCCAACTCATAAGGTTGCAGATAATTTAGAGATTATTACTGCAGG
AAGGATTTCATCCAATCCACTACCGATGTTGGAATCTGAACAATTTGCTAATTTTGTACAGGTTCAAATAGAACATTATG
ACTACATCCTTATTGATGCACCACCTCTGGTTTCTGTTGCTGATCCCCTTATTATTGGCAAAGTAGTTGATGGCATCCTA
TTAGTTGCTCGCCCAGGTCATTTAGAGCGTGAGTATGCTCAGAAAGCCCATGAGCTATTGATTCATTCAAATTTGAGTGT
TTTGGGAACGGTTATTAACGGAATTCTTAATAAGAATGAGCTTTATTCTTATTATTCGCGATATGGTCACAACTCTAATC
AAGAGAAGACTGCAATAAAGAGAAATTTATTAAAGCAAGTTATTTCAAAATAA

Upstream 100 bases:

>100_bases
TTTGTATTTCGTTTTTGAACGGTCTTTTGTCTAATCTGGTTACTGGTATCCACTCATGAATCAACCGTTAAATATTGTTC
AATCCTCTGAACAGTCTGAT

Downstream 100 bases:

>100_bases
GAATCATCTTGTTTGTTATCTACAGTATTTTTTTGATTTTTCTTAAAGTGATCATGAGTAACTATATTGTAATTATTAAG
GGCTATTTTGTGAATTTATT

Product: lipopolysaccharide biosynthesis protein

Products: ADP; protein tyrosine phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 710; Mature: 709

Protein sequence:

>710_residues
MSNYWLMLKRRGLPAGFTFLTVLSLALLQAFQEKPIYEAVGQLKFEESQRSSKLIGLDSAVDDESRQQSSLRWQRSLDTE
ILTMKSPRRLSMLALAIESQGLFSRPSVEQIKSGLDISQFDETNVVQIRFKSYNREFPKNIVNLLMQQYVDNTPKSKQAS
TQSAISFIEKQLPQVKQRVNSAETALRKFKETYQIADLEIAKSANATNLSQLQTALDEIDRELVEVQTQQLSLQNMLKVN
PQQAILGISTAHKNISTSLEEIDKDLAEAKSNFREDHPAVLELLERQAQLKQLLSQKIEKFAQSDAQLNFDSNQEDDLRS
QLIQLDIRRNGLSKQQLKLRQQLSSYRQQARNLPQLEQRQNELERTAKASASTYRNLLEQIQELKVTENQSPLTVSILES
ATDPEPSKTTFISAAMRGGLAGILLASGVVYVLERIDRKLKSKDEIRQVYPYRVLGEIPLFDESEAESLKLPTLSDPASH
LSEAYRMLQSSLKFHGLEHSPRVLMMTSAINQEGKSTTCANLAVSLAQMNHRVLLIDADIRLASQHQIWELGNQEGLTHI
LLNKHFNYHQELPTHKVADNLEIITAGRISSNPLPMLESEQFANFVQVQIEHYDYILIDAPPLVSVADPLIIGKVVDGIL
LVARPGHLEREYAQKAHELLIHSNLSVLGTVINGILNKNELYSYYSRYGHNSNQEKTAIKRNLLKQVISK

Sequences:

>Translated_710_residues
MSNYWLMLKRRGLPAGFTFLTVLSLALLQAFQEKPIYEAVGQLKFEESQRSSKLIGLDSAVDDESRQQSSLRWQRSLDTE
ILTMKSPRRLSMLALAIESQGLFSRPSVEQIKSGLDISQFDETNVVQIRFKSYNREFPKNIVNLLMQQYVDNTPKSKQAS
TQSAISFIEKQLPQVKQRVNSAETALRKFKETYQIADLEIAKSANATNLSQLQTALDEIDRELVEVQTQQLSLQNMLKVN
PQQAILGISTAHKNISTSLEEIDKDLAEAKSNFREDHPAVLELLERQAQLKQLLSQKIEKFAQSDAQLNFDSNQEDDLRS
QLIQLDIRRNGLSKQQLKLRQQLSSYRQQARNLPQLEQRQNELERTAKASASTYRNLLEQIQELKVTENQSPLTVSILES
ATDPEPSKTTFISAAMRGGLAGILLASGVVYVLERIDRKLKSKDEIRQVYPYRVLGEIPLFDESEAESLKLPTLSDPASH
LSEAYRMLQSSLKFHGLEHSPRVLMMTSAINQEGKSTTCANLAVSLAQMNHRVLLIDADIRLASQHQIWELGNQEGLTHI
LLNKHFNYHQELPTHKVADNLEIITAGRISSNPLPMLESEQFANFVQVQIEHYDYILIDAPPLVSVADPLIIGKVVDGIL
LVARPGHLEREYAQKAHELLIHSNLSVLGTVINGILNKNELYSYYSRYGHNSNQEKTAIKRNLLKQVISK
>Mature_709_residues
SNYWLMLKRRGLPAGFTFLTVLSLALLQAFQEKPIYEAVGQLKFEESQRSSKLIGLDSAVDDESRQQSSLRWQRSLDTEI
LTMKSPRRLSMLALAIESQGLFSRPSVEQIKSGLDISQFDETNVVQIRFKSYNREFPKNIVNLLMQQYVDNTPKSKQAST
QSAISFIEKQLPQVKQRVNSAETALRKFKETYQIADLEIAKSANATNLSQLQTALDEIDRELVEVQTQQLSLQNMLKVNP
QQAILGISTAHKNISTSLEEIDKDLAEAKSNFREDHPAVLELLERQAQLKQLLSQKIEKFAQSDAQLNFDSNQEDDLRSQ
LIQLDIRRNGLSKQQLKLRQQLSSYRQQARNLPQLEQRQNELERTAKASASTYRNLLEQIQELKVTENQSPLTVSILESA
TDPEPSKTTFISAAMRGGLAGILLASGVVYVLERIDRKLKSKDEIRQVYPYRVLGEIPLFDESEAESLKLPTLSDPASHL
SEAYRMLQSSLKFHGLEHSPRVLMMTSAINQEGKSTTCANLAVSLAQMNHRVLLIDADIRLASQHQIWELGNQEGLTHIL
LNKHFNYHQELPTHKVADNLEIITAGRISSNPLPMLESEQFANFVQVQIEHYDYILIDAPPLVSVADPLIIGKVVDGILL
VARPGHLEREYAQKAHELLIHSNLSVLGTVINGILNKNELYSYYSRYGHNSNQEKTAIKRNLLKQVISK

Specific function: Required for the extracellular polysaccharide colanic acid synthesis. The autophosphorylated form is inactive. Probably involved in the export of colanic acid from the cell to medium. Phosphorylates udg [H]

COG id: COG0489

COG function: function code D; ATPases involved in chromosome partitioning

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the etk/wzc family [H]

Homologues:

Organism=Escherichia coli, GI87082032, Length=444, Percent_Identity=29.2792792792793, Blast_Score=150, Evalue=3e-37,
Organism=Escherichia coli, GI1787216, Length=436, Percent_Identity=27.0642201834862, Blast_Score=142, Evalue=5e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR005702
- InterPro:   IPR003856 [H]

Pfam domain/function: PF01656 CbiA; PF02706 Wzz [H]

EC number: 2.7.1.112 [C]

Molecular weight: Translated: 80439; Mature: 80308

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNYWLMLKRRGLPAGFTFLTVLSLALLQAFQEKPIYEAVGQLKFEESQRSSKLIGLDSA
CCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHCCCEEECCCC
VDDESRQQSSLRWQRSLDTEILTMKSPRRLSMLALAIESQGLFSRPSVEQIKSGLDISQF
CCCHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCC
DETNVVQIRFKSYNREFPKNIVNLLMQQYVDNTPKSKQASTQSAISFIEKQLPQVKQRVN
CCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SAETALRKFKETYQIADLEIAKSANATNLSQLQTALDEIDRELVEVQTQQLSLQNMLKVN
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PQQAILGISTAHKNISTSLEEIDKDLAEAKSNFREDHPAVLELLERQAQLKQLLSQKIEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
FAQSDAQLNFDSNQEDDLRSQLIQLDIRRNGLSKQQLKLRQQLSSYRQQARNLPQLEQRQ
HHHCCCEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHH
NELERTAKASASTYRNLLEQIQELKVTENQSPLTVSILESATDPEPSKTTFISAAMRGGL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCH
AGILLASGVVYVLERIDRKLKSKDEIRQVYPYRVLGEIPLFDESEAESLKLPTLSDPASH
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHCCCCCCCCCCCCCCCCCCCCCHHHH
LSEAYRMLQSSLKFHGLEHSPRVLMMTSAINQEGKSTTCANLAVSLAQMNHRVLLIDADI
HHHHHHHHHHHHHHCCCCCCCCEEEEEHHHCCCCCCHHHHHHHHHHHHCCCEEEEEECCC
RLASQHQIWELGNQEGLTHILLNKHFNYHQELPTHKVADNLEIITAGRISSNPLPMLESE
EECCCHHHHHCCCCCCCHHHHHHCCCCHHHCCCCHHHHCCCEEEEECCCCCCCCCCCCHH
QFANFVQVQIEHYDYILIDAPPLVSVADPLIIGKVVDGILLVARPGHLEREYAQKAHELL
HHHHHHHEEEECCCEEEECCCCCHHHHCHHHHHHHHHCEEEEECCCCCHHHHHHHHHHHH
IHSNLSVLGTVINGILNKNELYSYYSRYGHNSNQEKTAIKRNLLKQVISK
HHCCHHHHHHHHHHHHCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SNYWLMLKRRGLPAGFTFLTVLSLALLQAFQEKPIYEAVGQLKFEESQRSSKLIGLDSA
CCEEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHCCCEEECCCC
VDDESRQQSSLRWQRSLDTEILTMKSPRRLSMLALAIESQGLFSRPSVEQIKSGLDISQF
CCCHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHCCCCCCCCCHHHHHCCCCCCCC
DETNVVQIRFKSYNREFPKNIVNLLMQQYVDNTPKSKQASTQSAISFIEKQLPQVKQRVN
CCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
SAETALRKFKETYQIADLEIAKSANATNLSQLQTALDEIDRELVEVQTQQLSLQNMLKVN
HHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PQQAILGISTAHKNISTSLEEIDKDLAEAKSNFREDHPAVLELLERQAQLKQLLSQKIEK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHH
FAQSDAQLNFDSNQEDDLRSQLIQLDIRRNGLSKQQLKLRQQLSSYRQQARNLPQLEQRQ
HHHCCCEECCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHH
NELERTAKASASTYRNLLEQIQELKVTENQSPLTVSILESATDPEPSKTTFISAAMRGGL
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCHHHHHHHHHHCCH
AGILLASGVVYVLERIDRKLKSKDEIRQVYPYRVLGEIPLFDESEAESLKLPTLSDPASH
HHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCHHHHCCCCCCCCCCCCCCCCCCCCCHHHH
LSEAYRMLQSSLKFHGLEHSPRVLMMTSAINQEGKSTTCANLAVSLAQMNHRVLLIDADI
HHHHHHHHHHHHHHCCCCCCCCEEEEEHHHCCCCCCHHHHHHHHHHHHCCCEEEEEECCC
RLASQHQIWELGNQEGLTHILLNKHFNYHQELPTHKVADNLEIITAGRISSNPLPMLESE
EECCCHHHHHCCCCCCCHHHHHHCCCCHHHCCCCHHHHCCCEEEEECCCCCCCCCCCCHH
QFANFVQVQIEHYDYILIDAPPLVSVADPLIIGKVVDGILLVARPGHLEREYAQKAHELL
HHHHHHHEEEECCCEEEECCCCCHHHHCHHHHHHHHHCEEEEECCCCCHHHHHHHHHHHH
IHSNLSVLGTVINGILNKNELYSYYSRYGHNSNQEKTAIKRNLLKQVISK
HHCCHHHHHHHHHHHHCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; a protein tyrosine [C]

Specific reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]