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The map label for this gene is moaC [H]

Identifier: 158333341

GI number: 158333341

Start: 119142

End: 119639

Strand: Direct

Name: moaC [H]

Synonym: AM1_0112

Alternate gene names: 158333341

Gene position: 119142-119639 (Clockwise)

Preceding gene: 158333340

Following gene: 158333342

Centisome position: 1.83

GC content: 50.8

Gene sequence:

>498_bases
ATGACGAATCAAAATCCAGCCCTGACTCACCTTGATCACCAGGGGGAAGCCCAAATGGTGGATGTTTCAGAAAAGGTTGC
AACGGTAAGGATGGCAACTGCCACGGGCCAGGTAAAGATGACCGGCAAAACCTTCGAAGCCATTCAAGCAGGGAATGCCC
CTAAAGGGGACGTTCTGGGGACTGCTCGACTCGCCGGAATCATGGCAGCAAAGCAAACCTCACAACTGATTCCCCTCTGT
CATCCTCTGCCGCTGAGTAAGGTTGAGGTTTCAATTCAGCCTCATCCAGACTTGCCCGGATATGAAATTCAAGTCCAGGT
AAAAACGAAGGCTGAAACGGGTGTGGAGATGGAGGCTCTCACAGCCGTTTCCATTGCGGCTTTAACGCTTTATGACATGG
CTAAAGCTCTGGATAAATCCATGCAGATCGTCAATGTCCATTTGCTGGAAAAGATTGGGGGGAAGTCTGGGCACTGGCGA
GTAGGTTCTACCGATTAG

Upstream 100 bases:

>100_bases
CTGAGCTACAAGCCCCTAAGGGATTATCATCTTACCACAGCCTAACATTATAGCAAGAACAACTTGTGAAAGCTGTCCAC
ATCAGGAGTTCCTCATCATC

Downstream 100 bases:

>100_bases
CAATGGTGGGTTGCGATCGCATTCCACCCGATCGGTTAAAACCCCAATTAGTCCTCTCATGCAAAGTTCATCTCCACTTC
AGGAGCCTTTCTGTTAGGGC

Product: molybdenum cofactor biosynthesis protein MoaC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 165; Mature: 164

Protein sequence:

>165_residues
MTNQNPALTHLDHQGEAQMVDVSEKVATVRMATATGQVKMTGKTFEAIQAGNAPKGDVLGTARLAGIMAAKQTSQLIPLC
HPLPLSKVEVSIQPHPDLPGYEIQVQVKTKAETGVEMEALTAVSIAALTLYDMAKALDKSMQIVNVHLLEKIGGKSGHWR
VGSTD

Sequences:

>Translated_165_residues
MTNQNPALTHLDHQGEAQMVDVSEKVATVRMATATGQVKMTGKTFEAIQAGNAPKGDVLGTARLAGIMAAKQTSQLIPLC
HPLPLSKVEVSIQPHPDLPGYEIQVQVKTKAETGVEMEALTAVSIAALTLYDMAKALDKSMQIVNVHLLEKIGGKSGHWR
VGSTD
>Mature_164_residues
TNQNPALTHLDHQGEAQMVDVSEKVATVRMATATGQVKMTGKTFEAIQAGNAPKGDVLGTARLAGIMAAKQTSQLIPLCH
PLPLSKVEVSIQPHPDLPGYEIQVQVKTKAETGVEMEALTAVSIAALTLYDMAKALDKSMQIVNVHLLEKIGGKSGHWRV
GSTD

Specific function: Together with moaA, is involved in the conversion of a guanosine derivative (5'-GTP) into molybdopterin precursor Z [H]

COG id: COG0315

COG function: function code H; Molybdenum cofactor biosynthesis enzyme

Gene ontology:
GO:0006777: Molybdenum cofactor biosynthesis protein C

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the moaC family [H]

Homologues:

Organism=Escherichia coli, GI1787001, Length=158, Percent_Identity=55.0632911392405, Blast_Score=159, Evalue=8e-41,
Organism=Caenorhabditis elegans, GI32566331, Length=151, Percent_Identity=41.7218543046358, Blast_Score=124, Evalue=3e-29,
Organism=Drosophila melanogaster, GI28574490, Length=153, Percent_Identity=49.0196078431373, Blast_Score=136, Evalue=6e-33,
Organism=Drosophila melanogaster, GI28574492, Length=142, Percent_Identity=47.1830985915493, Blast_Score=122, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023045
- InterPro:   IPR023046
- InterPro:   IPR002820 [H]

Pfam domain/function: PF01967 MoaC [H]

EC number: NA

Molecular weight: Translated: 17565; Mature: 17433

Theoretical pI: Translated: 7.16; Mature: 7.16

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNQNPALTHLDHQGEAQMVDVSEKVATVRMATATGQVKMTGKTFEAIQAGNAPKGDVLG
CCCCCCCEEECCCCCCEEEEECCHHHEEEEEEECCCEEEECCCHHHHHHCCCCCCCCCCH
TARLAGIMAAKQTSQLIPLCHPLPLSKVEVSIQPHPDLPGYEIQVQVKTKAETGVEMEAL
HHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEEEEECCCCCCCHHHH
TAVSIAALTLYDMAKALDKSMQIVNVHLLEKIGGKSGHWRVGSTD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCC
>Mature Secondary Structure 
TNQNPALTHLDHQGEAQMVDVSEKVATVRMATATGQVKMTGKTFEAIQAGNAPKGDVLG
CCCCCCEEECCCCCCEEEEECCHHHEEEEEEECCCEEEECCCHHHHHHCCCCCCCCCCH
TARLAGIMAAKQTSQLIPLCHPLPLSKVEVSIQPHPDLPGYEIQVQVKTKAETGVEMEAL
HHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCEEEEEEEEECCCCCCCHHHH
TAVSIAALTLYDMAKALDKSMQIVNVHLLEKIGGKSGHWRVGSTD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Involved in molybdopterin biosynthesis [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA