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The map label for this gene is tynA [H]

Identifier: 158318964

GI number: 158318964

Start: 8849522

End: 8851549

Strand: Direct

Name: tynA [H]

Synonym: Franean1_7247

Alternate gene names: 158318964

Gene position: 8849522-8851549 (Clockwise)

Preceding gene: 158318963

Following gene: 158318965

Centisome position: 98.52

GC content: 72.34

Gene sequence:

>2028_bases
ATGACGGTCAGTGCGTCCCCGGAGCCCGGGACGATCCCGGCGCGACCGGCGCATCCCCTCGAACCGCTGTCGGCCGCCGA
GATCGGCCGGGCCACCGCGATCCTGCGGGCGAGCGAGAAGCTCGGGCCGGAGTTTCGTTTCGTTTCCATCGAACTGAACG
AGCCACCAAAAGCCGCCCTGGTGTCGCGCGAGGCCGAGCGGGACGTCGGCGACGAGCTGGCCGCGCCGGACCGGCAGGCG
TTCTGCGTCCTGCACGAGCGCGGGGCGCGGCTGACCCACGAGGCCGTCGTGTCGCTGTCCGCCGGGACGGTGGTGGAGAT
GTACGTGGTCCCCGGCGTGCAGGCGGCGATGATGATGGAGGAGTTCCTGGCCTGCGAGGACGTCGTCCGTGCCGACCCGC
ACTGGCAGGCGGCGATGCGCAGGCGCGGGGTCACCGACTTCTCCCTCGCGATGATCGACCCGTGGTCCGCGGGCTACACC
GGGCGTGAGGACGACCCTGCCCGGCGGCGCATCGCGCGCCCGGTGACGTTCGTCCGCTCCGGGCCCGGCGAGAACGGCTA
CGCCCGGCCCGCGGAGGGACTGCAGGTCGTCGTCGACCTCGAGGCGATGGCCGTCGTCGACGTGACCGACCACGGCCAGG
GCCCGGACGGCCCTGTGCCGCTGCCGCCGCGCCCCGGCAACTACGCACCGGCGCTGATGACGGCCGCCCCGGAGAACGTC
CCCGCGTTCGACCGGCTGCGCGACGACCTGCGCCCGATCGAGGTCACCCAACCGCGCGGCGCCAGCTTCACCGTGGACGG
GTACGCCGTCCGGTGGCAGAAGTGGGACCTGCGCATCGGTTTCACCCCGCGCGAGGGCCTCATCCTGCACCAGGTCGCGT
ACACCGACCGGGGCCGGCGGCGGCCGATCCTGCAACGCGCGTCGGTGTCGGAGATGTTCGTCCCGTACGGCGACCCGGCG
CCGACGCACCGGGTGAAGAACGTCTTCGACATGGGCGAGTACGGGGTCGGGGTGACGGCCAACTCGCTGCGGCTCGGCTG
CGACTGCCTCGGCGACATCCGGTACTTCGACGGGGTCGTGAACGACTCCGACGGCAACCCGGTGACGATCCCGAACGCGG
TGTGCCTGCACGAGGAGGACACCGGAATCGCCTGGAAGCACACCGACTTCCGGACCGGCCAGGTCGAGGTCCGGCGGATG
CGCCGGCTGGTGATCTCGATGATCTGCACGGTCGGCAACTACGAGTACGGCTACTTCTGGTACCTCTATCTGGACGGCAC
CATCGAGTTCGAGGTGAAGCTGACCGGGGTCATCTCCACCGGGGCGGTGCGGCCGGGCGAGTCGCCGTCGCACGGGGTGC
TCGTGGCGCCCGGCCTGTACGGGCCGCATCACCAGCACTTCTTCAACGTGCGCCTGGACCTGGAGCTCGACGGCGGCCCG
AACTCGGTGCACGAGATCGACTCGGTGCCCGACCCCATCGGCCCGGACAACCCGACGGGCGTCGCCTGGCGGACCCAGGA
CACGCTGCTGGACTCGGAGCGCCACGCCCAGCGCAGGGTCGACCCGTCCGTCGCGCGGTTCTGGCGGATCACCAACCCGC
GCGTCGAGGGCCCGCTCGGCCGCCCGGTGGCCTACCGGCTCGTCCCGGGACACACGGCGCCGTTGCTGGCGCATCCCGAC
TCGCACCAGGCGGCGCGCGGGCGGTTCGCGTCCCGCAACCTGTGGGTGACCGCGTACGACGAGCGGGAGCGGTACGCCGC
CGGCCGCTACCCGAACCAGAACGCGGGCAACGAGGGCCTGCCGCAGTACGCGGCCGCGGACCGGCCGGTCGCCGACACCG
ACATCGTCGTCTGGTACAGCTTCGGGGCGCACCACGTCGTGCGCCCGGAGGACTGGCCGGTGATGCCGGTCAGCCGGATC
GGCTTCGAGCTGCGCCCGGACGGCTTCTTCGACGGCAACCCGGCCCTCGACCTGCCCCCGTCCGGGCACGTCGGTGGGGC
CGCGGACAGGCCCGGTCGTGCTGTTTAG

Upstream 100 bases:

>100_bases
GAACGGGCCGCCGATGGCCCGCGTTCGGCGACCTCTACTTTTGGGTGGCCCAGTCCCTTGCGTGCCGGGTCACGCACCCG
AGATGTTGGTGGAGTTCGCC

Downstream 100 bases:

>100_bases
CCGGGGCGTCGGCGGGCGGGCGCGCACGCGACACGCCCCGGCTGGAAGGGACGGCTTGCCCCGGAACGGGGGTAGCTGCC
CTAGGCTCCCGGAGTTGTGA

Product: tyramine oxidase

Products: NA

Alternate protein names: Copper amine oxidase; MAOXI [H]

Number of amino acids: Translated: 675; Mature: 674

Protein sequence:

>675_residues
MTVSASPEPGTIPARPAHPLEPLSAAEIGRATAILRASEKLGPEFRFVSIELNEPPKAALVSREAERDVGDELAAPDRQA
FCVLHERGARLTHEAVVSLSAGTVVEMYVVPGVQAAMMMEEFLACEDVVRADPHWQAAMRRRGVTDFSLAMIDPWSAGYT
GREDDPARRRIARPVTFVRSGPGENGYARPAEGLQVVVDLEAMAVVDVTDHGQGPDGPVPLPPRPGNYAPALMTAAPENV
PAFDRLRDDLRPIEVTQPRGASFTVDGYAVRWQKWDLRIGFTPREGLILHQVAYTDRGRRRPILQRASVSEMFVPYGDPA
PTHRVKNVFDMGEYGVGVTANSLRLGCDCLGDIRYFDGVVNDSDGNPVTIPNAVCLHEEDTGIAWKHTDFRTGQVEVRRM
RRLVISMICTVGNYEYGYFWYLYLDGTIEFEVKLTGVISTGAVRPGESPSHGVLVAPGLYGPHHQHFFNVRLDLELDGGP
NSVHEIDSVPDPIGPDNPTGVAWRTQDTLLDSERHAQRRVDPSVARFWRITNPRVEGPLGRPVAYRLVPGHTAPLLAHPD
SHQAARGRFASRNLWVTAYDERERYAAGRYPNQNAGNEGLPQYAAADRPVADTDIVVWYSFGAHHVVRPEDWPVMPVSRI
GFELRPDGFFDGNPALDLPPSGHVGGAADRPGRAV

Sequences:

>Translated_675_residues
MTVSASPEPGTIPARPAHPLEPLSAAEIGRATAILRASEKLGPEFRFVSIELNEPPKAALVSREAERDVGDELAAPDRQA
FCVLHERGARLTHEAVVSLSAGTVVEMYVVPGVQAAMMMEEFLACEDVVRADPHWQAAMRRRGVTDFSLAMIDPWSAGYT
GREDDPARRRIARPVTFVRSGPGENGYARPAEGLQVVVDLEAMAVVDVTDHGQGPDGPVPLPPRPGNYAPALMTAAPENV
PAFDRLRDDLRPIEVTQPRGASFTVDGYAVRWQKWDLRIGFTPREGLILHQVAYTDRGRRRPILQRASVSEMFVPYGDPA
PTHRVKNVFDMGEYGVGVTANSLRLGCDCLGDIRYFDGVVNDSDGNPVTIPNAVCLHEEDTGIAWKHTDFRTGQVEVRRM
RRLVISMICTVGNYEYGYFWYLYLDGTIEFEVKLTGVISTGAVRPGESPSHGVLVAPGLYGPHHQHFFNVRLDLELDGGP
NSVHEIDSVPDPIGPDNPTGVAWRTQDTLLDSERHAQRRVDPSVARFWRITNPRVEGPLGRPVAYRLVPGHTAPLLAHPD
SHQAARGRFASRNLWVTAYDERERYAAGRYPNQNAGNEGLPQYAAADRPVADTDIVVWYSFGAHHVVRPEDWPVMPVSRI
GFELRPDGFFDGNPALDLPPSGHVGGAADRPGRAV
>Mature_674_residues
TVSASPEPGTIPARPAHPLEPLSAAEIGRATAILRASEKLGPEFRFVSIELNEPPKAALVSREAERDVGDELAAPDRQAF
CVLHERGARLTHEAVVSLSAGTVVEMYVVPGVQAAMMMEEFLACEDVVRADPHWQAAMRRRGVTDFSLAMIDPWSAGYTG
REDDPARRRIARPVTFVRSGPGENGYARPAEGLQVVVDLEAMAVVDVTDHGQGPDGPVPLPPRPGNYAPALMTAAPENVP
AFDRLRDDLRPIEVTQPRGASFTVDGYAVRWQKWDLRIGFTPREGLILHQVAYTDRGRRRPILQRASVSEMFVPYGDPAP
THRVKNVFDMGEYGVGVTANSLRLGCDCLGDIRYFDGVVNDSDGNPVTIPNAVCLHEEDTGIAWKHTDFRTGQVEVRRMR
RLVISMICTVGNYEYGYFWYLYLDGTIEFEVKLTGVISTGAVRPGESPSHGVLVAPGLYGPHHQHFFNVRLDLELDGGPN
SVHEIDSVPDPIGPDNPTGVAWRTQDTLLDSERHAQRRVDPSVARFWRITNPRVEGPLGRPVAYRLVPGHTAPLLAHPDS
HQAARGRFASRNLWVTAYDERERYAAGRYPNQNAGNEGLPQYAAADRPVADTDIVVWYSFGAHHVVRPEDWPVMPVSRIG
FELRPDGFFDGNPALDLPPSGHVGGAADRPGRAV

Specific function: The exact function of maoXI is not known [H]

COG id: COG3733

COG function: function code Q; Cu2+-containing amine oxidase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the copper/topaquinone oxidase family [H]

Homologues:

Organism=Homo sapiens, GI73486661, Length=415, Percent_Identity=26.9879518072289, Blast_Score=124, Evalue=2e-28,
Organism=Homo sapiens, GI60498984, Length=434, Percent_Identity=28.110599078341, Blast_Score=105, Evalue=1e-22,
Organism=Homo sapiens, GI60498982, Length=430, Percent_Identity=27.6744186046512, Blast_Score=102, Evalue=2e-21,
Organism=Homo sapiens, GI4502119, Length=426, Percent_Identity=27.9342723004695, Blast_Score=100, Evalue=9e-21,
Organism=Escherichia coli, GI1787651, Length=660, Percent_Identity=30.1515151515152, Blast_Score=329, Evalue=4e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000269
- InterPro:   IPR015798
- InterPro:   IPR016182
- InterPro:   IPR015800
- InterPro:   IPR015801
- InterPro:   IPR015802 [H]

Pfam domain/function: PF01179 Cu_amine_oxid; PF02727 Cu_amine_oxidN2; PF02728 Cu_amine_oxidN3 [H]

EC number: =1.4.3.21 [H]

Molecular weight: Translated: 74231; Mature: 74100

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS01164 COPPER_AMINE_OXID_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVSASPEPGTIPARPAHPLEPLSAAEIGRATAILRASEKLGPEFRFVSIELNEPPKAAL
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHEEEHHHHCCCCEEEEEEEECCCCCHHH
VSREAERDVGDELAAPDRQAFCVLHERGARLTHEAVVSLSAGTVVEMYVVPGVQAAMMME
HHCHHHHCCCHHHCCCCCCEEEEEECCCCCEEEHHHEEECCCCEEEEEEECCCHHHHHHH
EFLACEDVVRADPHWQAAMRRRGVTDFSLAMIDPWSAGYTGREDDPARRRIARPVTFVRS
HHHHHHHHHHCCCCHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHCCEEEEEC
GPGENGYARPAEGLQVVVDLEAMAVVDVTDHGQGPDGPVPLPPRPGNYAPALMTAAPENV
CCCCCCCCCCCCCCEEEEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEECCCCCC
PAFDRLRDDLRPIEVTQPRGASFTVDGYAVRWQKWDLRIGFTPREGLILHQVAYTDRGRR
CHHHHHHHCCCCEEEECCCCCEEEECCEEEEEEEEEEEEECCCCCCEEEEEEECCCCCCC
RPILQRASVSEMFVPYGDPAPTHRVKNVFDMGEYGVGVTANSLRLGCDCLGDIRYFDGVV
CCHHHHCCHHHEEECCCCCCCHHHHHHHHHCCCCCCCEECCCEEECCHHHHCHHHHCCEE
NDSDGNPVTIPNAVCLHEEDTGIAWKHTDFRTGQVEVRRMRRLVISMICTVGNYEYGYFW
ECCCCCEEECCCEEEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEE
YLYLDGTIEFEVKLTGVISTGAVRPGESPSHGVLVAPGLYGPHHQHFFNVRLDLELDGGP
EEEECCEEEEEEEEEEEEEECCCCCCCCCCCCEEECCCCCCCCCCEEEEEEEEEEECCCC
NSVHEIDSVPDPIGPDNPTGVAWRTQDTLLDSERHAQRRVDPSVARFWRITNPRVEGPLG
CCHHHHHCCCCCCCCCCCCCEEEECHHHHHCCHHHHHHCCCHHHHHHEEECCCCCCCCCC
RPVAYRLVPGHTAPLLAHPDSHQAARGRFASRNLWVTAYDERERYAAGRYPNQNAGNEGL
CCEEEEEECCCCCCEEECCCCCHHHHCCCCCCCEEEEEECCCHHHHCCCCCCCCCCCCCC
PQYAAADRPVADTDIVVWYSFGAHHVVRPEDWPVMPVSRIGFELRPDGFFDGNPALDLPP
CCHHCCCCCCCCCCEEEEEECCCCEEECCCCCCCCCHHHCCEEECCCCCCCCCCCCCCCC
SGHVGGAADRPGRAV
CCCCCCCCCCCCCCC
>Mature Secondary Structure 
TVSASPEPGTIPARPAHPLEPLSAAEIGRATAILRASEKLGPEFRFVSIELNEPPKAAL
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHEEEHHHHCCCCEEEEEEEECCCCCHHH
VSREAERDVGDELAAPDRQAFCVLHERGARLTHEAVVSLSAGTVVEMYVVPGVQAAMMME
HHCHHHHCCCHHHCCCCCCEEEEEECCCCCEEEHHHEEECCCCEEEEEEECCCHHHHHHH
EFLACEDVVRADPHWQAAMRRRGVTDFSLAMIDPWSAGYTGREDDPARRRIARPVTFVRS
HHHHHHHHHHCCCCHHHHHHHCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHCCEEEEEC
GPGENGYARPAEGLQVVVDLEAMAVVDVTDHGQGPDGPVPLPPRPGNYAPALMTAAPENV
CCCCCCCCCCCCCCEEEEEEEEEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEECCCCCC
PAFDRLRDDLRPIEVTQPRGASFTVDGYAVRWQKWDLRIGFTPREGLILHQVAYTDRGRR
CHHHHHHHCCCCEEEECCCCCEEEECCEEEEEEEEEEEEECCCCCCEEEEEEECCCCCCC
RPILQRASVSEMFVPYGDPAPTHRVKNVFDMGEYGVGVTANSLRLGCDCLGDIRYFDGVV
CCHHHHCCHHHEEECCCCCCCHHHHHHHHHCCCCCCCEECCCEEECCHHHHCHHHHCCEE
NDSDGNPVTIPNAVCLHEEDTGIAWKHTDFRTGQVEVRRMRRLVISMICTVGNYEYGYFW
ECCCCCEEECCCEEEEECCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEE
YLYLDGTIEFEVKLTGVISTGAVRPGESPSHGVLVAPGLYGPHHQHFFNVRLDLELDGGP
EEEECCEEEEEEEEEEEEEECCCCCCCCCCCCEEECCCCCCCCCCEEEEEEEEEEECCCC
NSVHEIDSVPDPIGPDNPTGVAWRTQDTLLDSERHAQRRVDPSVARFWRITNPRVEGPLG
CCHHHHHCCCCCCCCCCCCCEEEECHHHHHCCHHHHHHCCCHHHHHHEEECCCCCCCCCC
RPVAYRLVPGHTAPLLAHPDSHQAARGRFASRNLWVTAYDERERYAAGRYPNQNAGNEGL
CCEEEEEECCCCCCEEECCCCCHHHHCCCCCCCEEEEEECCCHHHHCCCCCCCCCCCCCC
PQYAAADRPVADTDIVVWYSFGAHHVVRPEDWPVMPVSRIGFELRPDGFFDGNPALDLPP
CCHHCCCCCCCCCCEEEEEECCCCEEECCCCCCCCCHHHCCEEECCCCCCCCCCCCCCCC
SGHVGGAADRPGRAV
CCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8366046 [H]