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The map label for this gene is cutR [H]

Identifier: 158318852

GI number: 158318852

Start: 8713946

End: 8714677

Strand: Direct

Name: cutR [H]

Synonym: Franean1_7133

Alternate gene names: 158318852

Gene position: 8713946-8714677 (Clockwise)

Preceding gene: 158318851

Following gene: 158318853

Centisome position: 97.02

GC content: 65.03

Gene sequence:

>732_bases
ATGCCGACGATATGCGCAGGTCGTACCATCGAGAGTGTGCGTGTGTTGGTCGTCGAAGATGAGCCGTACATGGCAGAGGC
CATCCGCGATGGGCTGCGTCTGGAAGCGATCGCGGCCGATATCGCCGGTGACGGTGACACCGCTCTGGAGCTGTTGAGCA
TCAACGCCTACGACATCGCCGTCCTCGACCGCGACATTCCCGGGCCTTCCGGTGACGAGATCGCCGAAAGCATCGTCGCC
TCCGGCTGCGGCATGCCGATCCTGATGCTCACCGCTGCGGACCGGCTTGACGACAAGGCCTCCGGGTTCGAGCTCGGAGC
CGACGACTACCTCACCAAGCCGTTCGAGCTGCGAGAGCTCGTGCTCAGGCTCAGGGCACTCGACCGCAGGCGCGCGCACA
TCAGGCCGCCCGTGTGGGAGATCGCAGGTCTGCGTCTGGATCCGTTTCGCCGCGAGGTCTACCGGGACGGCCGATATGTC
GCGCTGACCAGGAAGCAGTTCGCCGTGCTCGAAGTTCTCGTCGCTGCCGAAGGCGGTGTCATTAGCACCGAAGAGCTGCT
GGAACGGGCGTGGGATGAGAATGCCGACCCGTTCACCAACGCCGTGCGTATAACGGTCTCGGCCCTGCGCAAACGCCTCG
GCGAACCCTGGATCATCGCCACCGTGCCCAGCGTTGGGTACCGCATCGACACAGCACCCGGCACCGGGCGTGAGGGAGGG
GACCGTGGATAG

Upstream 100 bases:

>100_bases
CGCCCGGAGGCCGGGGAGCCGCCCGGCGCCGGCCCGACCGGGGTCACGAGGTGAACATCCGGACCGGCGCGGTGCTGCCA
ACACGCATGTAATTTTCGAT

Downstream 100 bases:

>100_bases
GGCGCCCGGTTTGAGCGTTCGCCTCAAACTCACCCTCAGCTACGCCGGCTTCCTCATGCTTGCGGGTGTCTTGCTGCTCG
CGGTCGTGTGGGTGTTCCTG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: Defective melC1 suppressor protein [H]

Number of amino acids: Translated: 243; Mature: 242

Protein sequence:

>243_residues
MPTICAGRTIESVRVLVVEDEPYMAEAIRDGLRLEAIAADIAGDGDTALELLSINAYDIAVLDRDIPGPSGDEIAESIVA
SGCGMPILMLTAADRLDDKASGFELGADDYLTKPFELRELVLRLRALDRRRAHIRPPVWEIAGLRLDPFRREVYRDGRYV
ALTRKQFAVLEVLVAAEGGVISTEELLERAWDENADPFTNAVRITVSALRKRLGEPWIIATVPSVGYRIDTAPGTGREGG
DRG

Sequences:

>Translated_243_residues
MPTICAGRTIESVRVLVVEDEPYMAEAIRDGLRLEAIAADIAGDGDTALELLSINAYDIAVLDRDIPGPSGDEIAESIVA
SGCGMPILMLTAADRLDDKASGFELGADDYLTKPFELRELVLRLRALDRRRAHIRPPVWEIAGLRLDPFRREVYRDGRYV
ALTRKQFAVLEVLVAAEGGVISTEELLERAWDENADPFTNAVRITVSALRKRLGEPWIIATVPSVGYRIDTAPGTGREGG
DRG
>Mature_242_residues
PTICAGRTIESVRVLVVEDEPYMAEAIRDGLRLEAIAADIAGDGDTALELLSINAYDIAVLDRDIPGPSGDEIAESIVAS
GCGMPILMLTAADRLDDKASGFELGADDYLTKPFELRELVLRLRALDRRRAHIRPPVWEIAGLRLDPFRREVYRDGRYVA
LTRKQFAVLEVLVAAEGGVISTEELLERAWDENADPFTNAVRITVSALRKRLGEPWIIATVPSVGYRIDTAPGTGREGGD
RG

Specific function: Member of the two-component regulatory system CutS/CutR, involved in the regulation of copper metabolism. CutR suppresses a defective melC1 gene, encoding a putative copper-transfer gene, probably by altering copper metabolism [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786784, Length=226, Percent_Identity=36.283185840708, Blast_Score=139, Evalue=2e-34,
Organism=Escherichia coli, GI87082012, Length=218, Percent_Identity=33.4862385321101, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1789402, Length=217, Percent_Identity=34.5622119815668, Blast_Score=114, Evalue=4e-27,
Organism=Escherichia coli, GI1790552, Length=217, Percent_Identity=32.258064516129, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=33.4801762114537, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1789809, Length=228, Percent_Identity=30.7017543859649, Blast_Score=99, Evalue=3e-22,
Organism=Escherichia coli, GI2367329, Length=233, Percent_Identity=32.1888412017167, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1790860, Length=201, Percent_Identity=31.3432835820896, Blast_Score=97, Evalue=8e-22,
Organism=Escherichia coli, GI1787375, Length=218, Percent_Identity=28.4403669724771, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1788394, Length=221, Percent_Identity=31.6742081447964, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1787229, Length=215, Percent_Identity=27.906976744186, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1790863, Length=233, Percent_Identity=29.1845493562232, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1786911, Length=230, Percent_Identity=31.7391304347826, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI1788550, Length=216, Percent_Identity=24.0740740740741, Blast_Score=63, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26615; Mature: 26483

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS01319 RBFA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTICAGRTIESVRVLVVEDEPYMAEAIRDGLRLEAIAADIAGDGDTALELLSINAYDIA
CCCCCCCCCCCCEEEEEEECCCHHHHHHHCCCEEEEHHHHHCCCCCCEEEEEECCCEEEE
VLDRDIPGPSGDEIAESIVASGCGMPILMLTAADRLDDKASGFELGADDYLTKPFELREL
EEECCCCCCCHHHHHHHHHHCCCCCCEEEEEHHHHCCCCCCCCCCCCHHHCCCCHHHHHH
VLRLRALDRRRAHIRPPVWEIAGLRLDPFRREVYRDGRYVALTRKQFAVLEVLVAAEGGV
HHHHHHHHHHHHCCCCCHHHHCCCCCCHHHHHHHCCCCEEEEEHHHHHHHHHHHHCCCCE
ISTEELLERAWDENADPFTNAVRITVSALRKRLGEPWIIATVPSVGYRIDTAPGTGREGG
ECHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEECCCCCCCCCC
DRG
CCC
>Mature Secondary Structure 
PTICAGRTIESVRVLVVEDEPYMAEAIRDGLRLEAIAADIAGDGDTALELLSINAYDIA
CCCCCCCCCCCEEEEEEECCCHHHHHHHCCCEEEEHHHHHCCCCCCEEEEEECCCEEEE
VLDRDIPGPSGDEIAESIVASGCGMPILMLTAADRLDDKASGFELGADDYLTKPFELREL
EEECCCCCCCHHHHHHHHHHCCCCCCEEEEEHHHHCCCCCCCCCCCCHHHCCCCHHHHHH
VLRLRALDRRRAHIRPPVWEIAGLRLDPFRREVYRDGRYVALTRKQFAVLEVLVAAEGGV
HHHHHHHHHHHHCCCCCHHHHCCCCCCHHHHHHHCCCCEEEEEHHHHHHHHHHHHCCCCE
ISTEELLERAWDENADPFTNAVRITVSALRKRLGEPWIIATVPSVGYRIDTAPGTGREGG
ECHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCEEEEECCCCCEEEECCCCCCCCCC
DRG
CCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]