| Definition | Frankia sp. EAN1pec chromosome, complete genome. |
|---|---|
| Accession | NC_009921 |
| Length | 8,982,042 |
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The map label for this gene is aceE [H]
Identifier: 158318746
GI number: 158318746
Start: 8556315
End: 8559128
Strand: Direct
Name: aceE [H]
Synonym: Franean1_7017
Alternate gene names: 158318746
Gene position: 8556315-8559128 (Clockwise)
Preceding gene: 158318743
Following gene: 158318747
Centisome position: 95.26
GC content: 68.27
Gene sequence:
>2814_bases ATGCGAACGGTCATCACCGACGGGCTCCCGAGCCAGTTGCCGGACATCGATCCGTCCGAAACCAGCGAATGGCTCGAGTC GCTCGACGCGGTGATCGAGGAGTCCGGGCGAGGCCGGGCACGGTTCCTCATGCTCAAACTCCTCGAACGGGCACGCGAGA AGGCGGTCGGGGTACCGGGCCTGACCAGCACCGACTTCATCAACACGATCCCCCCCGAGCAGGAACCCTGGTTCCCGGGC GACGAGCACGTCGAACGGCGGATCCGGGCGTACATCCGGTGGAACGCCGCCATCATGGTCAGCCGCGCGAACCGTCCGGA ATATAATGTCGGCGGCCATATCGCCACATATGCCTCGAGCGCGAGCCTGTACGAGGTCGGCTTCAATCATTTCTTCCGGG GCAAGGACCACCTGACCTCCTCCCCCGGCAGCGATTCCGGGGACCAGATCTTCATCCAGGGGCACGCCTCCCCCGGCATC TACGCCCGCGCGTTCCTCGAGGGCCGTCTCACCGAGGCACAGCTGGACGCGTTCCGCCGCGAGGGCGAGCCGGGCGGCCT GTCGTCCTACCCGCACCCCCGGCTGATGCCGGACTTCTGGGAGTTCCCGACAGTGTCGATGGGCCTCGGCCCGATCGACG CCATCTACCAGGCGCGGTTCAACCGCTACCTGCTCAACCGCCAGATCAAGGACACCTCCCGCAGCAAGGTGTGGGCGTTC CTCGGCGACGGCGAGATGGACGAGCCGGAGTCGATCGGCGCCCTCGGGGTCGCCGCCCGCGAGGAGCTCGACAACCTCAT CTTCGTGGTGAACTGCAACCTGCAGCGCCTCGACGGGCCGGTCCGCGGCAACGGCAAGATCATGCAGGAGCTGGAGTCGC TGTTCCGCGGCGCCGGCTGGAACGTCATCAAAGTCGTCTGGGGCCGTGACTGGGACCCGCTGCTCGCCAAGGACACCGAC GGCGTCCTCGTCCACCGGATGAACACCACACCCGACGGCCAGTTCCAGACCTACTCGACCTCGTCAGGCGACTACATCCG GGAGCACTTCTTCGGCGCCGACGCCCGGCTACGCCGGATGGTCACCGACCTGGCCGACGAGGATCTCAGCAAGCTCTCCC GCGGCGGGCACGACTACCGCAAGCTGTACGCGGCCTACAAGGCGGCCACGGAGCATGCCGGTCAGCCCACCGTGATCCTC GCCCACACGATCAAGGGCTGGACGCTGGGCAAGGACTTCGAGGGCCGCAACGCCACGCACCAGATGAAGAAGCTCACCAA GACCGAGCTCAAGGAGCTGCGCGACCGGCTCTACCTGGAAATCCCCGACTCGGCGCTGGACGGCAACCTCCCGCCGTACT ACCGCCCGGGGCCGGACTCCGAGGAGATCCAGTACATGCGGGAACGCCGGGCGGGGCTCGGCGGATCGATCCCGCGCCGC GTGGTGCACGCCCGCACCCTCCCCCAGCCACCAAAGTCGATCTTCGACGAGCTGCGGCGGGGCTCGGGCAAGCAGCCGGT GGCCACGACAATGGCCATCGTCCGCCTACTCAAGGACCTGATGAAGACCAAGGAGATGGGCGCCCGGTTCGTGCCCGTCA TCCCGGACGAGGCGCGCACGTTCGGCATGGACGCGATGTTCCCCACAGCGAAGATCTACTCGCCGCACGGGCAGCGCTAC GAGGCCGTCGACCGGGAGCTGCTGCTCTCCTACCGGGAGTCCGAGTCCGGCCAGATGCTGCACGAGGGCATCAGCGAGGC CGGTTCGATGGGCTCGGTGATCGCCGCCGCGACGGCGTACTCCACCCACGGCCAGCACATGATCCCGGTGTACGTCTTCT ACTCGATGTTCGGCTTCCAGCGGACCGGCGACCAGATGTGGGCGCTCGGCGACCAGCTCGGCCGGGCCTTCCTACTCGGC GCCACCGCGGGGCGCACGACCCTGAACGGCGAGGGCCTACAGCACCAGGACGGCCACTCGCTACTGCTGGCATCCACGAA CCCGGCGTGCGTGTCGTACGACCCGGCGTTCGCGTTCGAGATCTCCCACATCGTCCGCGACGCCCTCGACCGGATGTACG GCGAGCGGAACGAGAACGTCTTCTACTACCTGACCGTCTACAACGAGCCGGTCCCGCAGCCAGCCGAGCCGACCGGGGTC GACCCGACCCAGATCATCGCCGGCATGTACCGGTTCCGTACCGCCGACGCGCTCACCGGCGGCGAGGAGACACCCACCGG GCCGGTCGAGGACGGGGCCACCGAGAGCTCCACCACGACGCAGGCACAGCTCCTGGCCAGCGGTACCGGCATGCGCTGGG CGCTGGCCGCCCAGGAGATGCTGGCGGCCGACTACGGCATCGCCGCCGACGTGTGGTCAGTGACCTCGTGGAACGAACTG CGCCGGGAAGCACTGGTATGCGAGCGGCGCAACCTGCTCAACCCCGAGCAGCCGCCAGCCGTGCCCTACATCAGCCAGAT CCTGAACGGCGCACCAGGCCCGGTCATCGCGGTCTCGGACTGGATGCGCGCCGTCCCCGACCAGATCTCACGGTGGGTGC CACAGCCGTACACCTCGCTGGGCACCGACGGCTTCGGCCGCTCCGACACCCGGGCGGCCCTACGGCGCCACTTCAACGTC GACGCCGAGTCCGTGGTCGTGGCGACCCTGGAGGCACTGACACGAACAGGTGACGTCGAGCAGGCCACCGTGGACGACGC CATCCGCCGGTACGGGCTACGCAAGGACGGCGCCAACGAGGCCGCTCTCGGCAACGGCGCCACGGAAGAGAACGACCAGC CAGTCTCCGGCTGA
Upstream 100 bases:
>100_bases GCAATAACGGACTATCCACACTCCCCGATGCAAGTGGGGCGTCACGAATCTCCATGGAAATCTCGACAAACCTCCGCCGA GCGAGAAGGTTCGGATACTA
Downstream 100 bases:
>100_bases CCAGGCGCGGCCGGTCAGCCATGTCACCGAAGCCACTCGCACGGGAAACCTGCCTACCCCCGAACTCTTCGAGAGTAGGC AGGCTGCTGGGTCGACCAGA
Product: pyruvate dehydrogenase subunit E1
Products: NA
Alternate protein names: NA
Number of amino acids: Translated: 937; Mature: 937
Protein sequence:
>937_residues MRTVITDGLPSQLPDIDPSETSEWLESLDAVIEESGRGRARFLMLKLLERAREKAVGVPGLTSTDFINTIPPEQEPWFPG DEHVERRIRAYIRWNAAIMVSRANRPEYNVGGHIATYASSASLYEVGFNHFFRGKDHLTSSPGSDSGDQIFIQGHASPGI YARAFLEGRLTEAQLDAFRREGEPGGLSSYPHPRLMPDFWEFPTVSMGLGPIDAIYQARFNRYLLNRQIKDTSRSKVWAF LGDGEMDEPESIGALGVAAREELDNLIFVVNCNLQRLDGPVRGNGKIMQELESLFRGAGWNVIKVVWGRDWDPLLAKDTD GVLVHRMNTTPDGQFQTYSTSSGDYIREHFFGADARLRRMVTDLADEDLSKLSRGGHDYRKLYAAYKAATEHAGQPTVIL AHTIKGWTLGKDFEGRNATHQMKKLTKTELKELRDRLYLEIPDSALDGNLPPYYRPGPDSEEIQYMRERRAGLGGSIPRR VVHARTLPQPPKSIFDELRRGSGKQPVATTMAIVRLLKDLMKTKEMGARFVPVIPDEARTFGMDAMFPTAKIYSPHGQRY EAVDRELLLSYRESESGQMLHEGISEAGSMGSVIAAATAYSTHGQHMIPVYVFYSMFGFQRTGDQMWALGDQLGRAFLLG ATAGRTTLNGEGLQHQDGHSLLLASTNPACVSYDPAFAFEISHIVRDALDRMYGERNENVFYYLTVYNEPVPQPAEPTGV DPTQIIAGMYRFRTADALTGGEETPTGPVEDGATESSTTTQAQLLASGTGMRWALAAQEMLAADYGIAADVWSVTSWNEL RREALVCERRNLLNPEQPPAVPYISQILNGAPGPVIAVSDWMRAVPDQISRWVPQPYTSLGTDGFGRSDTRAALRRHFNV DAESVVVATLEALTRTGDVEQATVDDAIRRYGLRKDGANEAALGNGATEENDQPVSG
Sequences:
>Translated_937_residues MRTVITDGLPSQLPDIDPSETSEWLESLDAVIEESGRGRARFLMLKLLERAREKAVGVPGLTSTDFINTIPPEQEPWFPG DEHVERRIRAYIRWNAAIMVSRANRPEYNVGGHIATYASSASLYEVGFNHFFRGKDHLTSSPGSDSGDQIFIQGHASPGI YARAFLEGRLTEAQLDAFRREGEPGGLSSYPHPRLMPDFWEFPTVSMGLGPIDAIYQARFNRYLLNRQIKDTSRSKVWAF LGDGEMDEPESIGALGVAAREELDNLIFVVNCNLQRLDGPVRGNGKIMQELESLFRGAGWNVIKVVWGRDWDPLLAKDTD GVLVHRMNTTPDGQFQTYSTSSGDYIREHFFGADARLRRMVTDLADEDLSKLSRGGHDYRKLYAAYKAATEHAGQPTVIL AHTIKGWTLGKDFEGRNATHQMKKLTKTELKELRDRLYLEIPDSALDGNLPPYYRPGPDSEEIQYMRERRAGLGGSIPRR VVHARTLPQPPKSIFDELRRGSGKQPVATTMAIVRLLKDLMKTKEMGARFVPVIPDEARTFGMDAMFPTAKIYSPHGQRY EAVDRELLLSYRESESGQMLHEGISEAGSMGSVIAAATAYSTHGQHMIPVYVFYSMFGFQRTGDQMWALGDQLGRAFLLG ATAGRTTLNGEGLQHQDGHSLLLASTNPACVSYDPAFAFEISHIVRDALDRMYGERNENVFYYLTVYNEPVPQPAEPTGV DPTQIIAGMYRFRTADALTGGEETPTGPVEDGATESSTTTQAQLLASGTGMRWALAAQEMLAADYGIAADVWSVTSWNEL RREALVCERRNLLNPEQPPAVPYISQILNGAPGPVIAVSDWMRAVPDQISRWVPQPYTSLGTDGFGRSDTRAALRRHFNV DAESVVVATLEALTRTGDVEQATVDDAIRRYGLRKDGANEAALGNGATEENDQPVSG >Mature_937_residues MRTVITDGLPSQLPDIDPSETSEWLESLDAVIEESGRGRARFLMLKLLERAREKAVGVPGLTSTDFINTIPPEQEPWFPG DEHVERRIRAYIRWNAAIMVSRANRPEYNVGGHIATYASSASLYEVGFNHFFRGKDHLTSSPGSDSGDQIFIQGHASPGI YARAFLEGRLTEAQLDAFRREGEPGGLSSYPHPRLMPDFWEFPTVSMGLGPIDAIYQARFNRYLLNRQIKDTSRSKVWAF LGDGEMDEPESIGALGVAAREELDNLIFVVNCNLQRLDGPVRGNGKIMQELESLFRGAGWNVIKVVWGRDWDPLLAKDTD GVLVHRMNTTPDGQFQTYSTSSGDYIREHFFGADARLRRMVTDLADEDLSKLSRGGHDYRKLYAAYKAATEHAGQPTVIL AHTIKGWTLGKDFEGRNATHQMKKLTKTELKELRDRLYLEIPDSALDGNLPPYYRPGPDSEEIQYMRERRAGLGGSIPRR VVHARTLPQPPKSIFDELRRGSGKQPVATTMAIVRLLKDLMKTKEMGARFVPVIPDEARTFGMDAMFPTAKIYSPHGQRY EAVDRELLLSYRESESGQMLHEGISEAGSMGSVIAAATAYSTHGQHMIPVYVFYSMFGFQRTGDQMWALGDQLGRAFLLG ATAGRTTLNGEGLQHQDGHSLLLASTNPACVSYDPAFAFEISHIVRDALDRMYGERNENVFYYLTVYNEPVPQPAEPTGV DPTQIIAGMYRFRTADALTGGEETPTGPVEDGATESSTTTQAQLLASGTGMRWALAAQEMLAADYGIAADVWSVTSWNEL RREALVCERRNLLNPEQPPAVPYISQILNGAPGPVIAVSDWMRAVPDQISRWVPQPYTSLGTDGFGRSDTRAALRRHFNV DAESVVVATLEALTRTGDVEQATVDDAIRRYGLRKDGANEAALGNGATEENDQPVSG
Specific function: The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components:pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydroge
COG id: COG2609
COG function: function code C; Pyruvate dehydrogenase complex, dehydrogenase (E1) component
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: NA
Homologues:
Organism=Escherichia coli, GI1786304, Length=908, Percent_Identity=50.5506607929515, Blast_Score=917, Evalue=0.0,
Paralogues:
None
Copy number: 1140 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 400 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 6,000 Molecules/Cell In: Glucose minimal media [C]
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR004660 - InterPro: IPR009014 - InterPro: IPR015941 - InterPro: IPR005474 [H]
Pfam domain/function: PF00456 Transketolase_N [H]
EC number: =1.2.4.1 [H]
Molecular weight: Translated: 103850; Mature: 103850
Theoretical pI: Translated: 5.36; Mature: 5.36
Prosite motif: NA
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.3 %Cys (Translated Protein) 2.8 %Met (Translated Protein) 3.1 %Cys+Met (Translated Protein) 0.3 %Cys (Mature Protein) 2.8 %Met (Mature Protein) 3.1 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MRTVITDGLPSQLPDIDPSETSEWLESLDAVIEESGRGRARFLMLKLLERAREKAVGVPG CCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCC LTSTDFINTIPPEQEPWFPGDEHVERRIRAYIRWNAAIMVSRANRPEYNVGGHIATYASS CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHEECEEEEEEECCCCCCCCCCCCEECCCC ASLYEVGFNHFFRGKDHLTSSPGSDSGDQIFIQGHASPGIYARAFLEGRLTEAQLDAFRR CHHHHHHHHHHHCCCHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHH EGEPGGLSSYPHPRLMPDFWEFPTVSMGLGPIDAIYQARFNRYLLNRQIKDTSRSKVWAF CCCCCCCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE LGDGEMDEPESIGALGVAAREELDNLIFVVNCNLQRLDGPVRGNGKIMQELESLFRGAGW ECCCCCCCCHHCCHHHHHHHHHHCCEEEEEECCHHHCCCCCCCCCHHHHHHHHHHCCCCC NVIKVVWGRDWDPLLAKDTDGVLVHRMNTTPDGQFQTYSTSSGDYIREHFFGADARLRRM CEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCEEEECCCCCHHHHHHHCCCHHHHHHH VTDLADEDLSKLSRGGHDYRKLYAAYKAATEHAGQPTVILAHTIKGWTLGKDFEGRNATH HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCHHH QMKKLTKTELKELRDRLYLEIPDSALDGNLPPYYRPGPDSEEIQYMRERRAGLGGSIPRR HHHHHHHHHHHHHHHHEEEECCCHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHH VVHARTLPQPPKSIFDELRRGSGKQPVATTMAIVRLLKDLMKTKEMGARFVPVIPDEART HHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHH FGMDAMFPTAKIYSPHGQRYEAVDRELLLSYRESESGQMLHEGISEAGSMGSVIAAATAY CCCHHCCCCCEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHH STHGQHMIPVYVFYSMFGFQRTGDQMWALGDQLGRAFLLGATAGRTTLNGEGLQHQDGHS CCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCE LLLASTNPACVSYDPAFAFEISHIVRDALDRMYGERNENVFYYLTVYNEPVPQPAEPTGV EEEEECCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCC DPTQIIAGMYRFRTADALTGGEETPTGPVEDGATESSTTTQAQLLASGTGMRWALAAQEM CHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHH LAADYGIAADVWSVTSWNELRREALVCERRNLLNPEQPPAVPYISQILNGAPGPVIAVSD HHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCEEEHHH WMRAVPDQISRWVPQPYTSLGTDGFGRSDTRAALRRHFNVDAESVVVATLEALTRTGDVE HHHHHHHHHHHHCCCCHHHCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCH QATVDDAIRRYGLRKDGANEAALGNGATEENDQPVSG HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC >Mature Secondary Structure MRTVITDGLPSQLPDIDPSETSEWLESLDAVIEESGRGRARFLMLKLLERAREKAVGVPG CCCEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCC LTSTDFINTIPPEQEPWFPGDEHVERRIRAYIRWNAAIMVSRANRPEYNVGGHIATYASS CCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHEECEEEEEEECCCCCCCCCCCCEECCCC ASLYEVGFNHFFRGKDHLTSSPGSDSGDQIFIQGHASPGIYARAFLEGRLTEAQLDAFRR CHHHHHHHHHHHCCCHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHCCCHHHHHHHHHH EGEPGGLSSYPHPRLMPDFWEFPTVSMGLGPIDAIYQARFNRYLLNRQIKDTSRSKVWAF CCCCCCCCCCCCCCCCCHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEE LGDGEMDEPESIGALGVAAREELDNLIFVVNCNLQRLDGPVRGNGKIMQELESLFRGAGW ECCCCCCCCHHCCHHHHHHHHHHCCEEEEEECCHHHCCCCCCCCCHHHHHHHHHHCCCCC NVIKVVWGRDWDPLLAKDTDGVLVHRMNTTPDGQFQTYSTSSGDYIREHFFGADARLRRM CEEEEEECCCCCCCCCCCCCCEEEEEECCCCCCCEEEECCCCCHHHHHHHCCCHHHHHHH VTDLADEDLSKLSRGGHDYRKLYAAYKAATEHAGQPTVILAHTIKGWTLGKDFEGRNATH HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCCCCHHH QMKKLTKTELKELRDRLYLEIPDSALDGNLPPYYRPGPDSEEIQYMRERRAGLGGSIPRR HHHHHHHHHHHHHHHHEEEECCCHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHH VVHARTLPQPPKSIFDELRRGSGKQPVATTMAIVRLLKDLMKTKEMGARFVPVIPDEART HHHHCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCHHH FGMDAMFPTAKIYSPHGQRYEAVDRELLLSYRESESGQMLHEGISEAGSMGSVIAAATAY CCCHHCCCCCEEECCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHH STHGQHMIPVYVFYSMFGFQRTGDQMWALGDQLGRAFLLGATAGRTTLNGEGLQHQDGHS CCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHCCEEEEECCCCCCCCCCCCCCCCCCCE LLLASTNPACVSYDPAFAFEISHIVRDALDRMYGERNENVFYYLTVYNEPVPQPAEPTGV EEEEECCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEEECCCCCCCCCCCCC DPTQIIAGMYRFRTADALTGGEETPTGPVEDGATESSTTTQAQLLASGTGMRWALAAQEM CHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCCCHHHHHHHH LAADYGIAADVWSVTSWNELRREALVCERRNLLNPEQPPAVPYISQILNGAPGPVIAVSD HHHHCCCHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHCCCCCCEEEHHH WMRAVPDQISRWVPQPYTSLGTDGFGRSDTRAALRRHFNVDAESVVVATLEALTRTGDVE HHHHHHHHHHHHCCCCHHHCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCH QATVDDAIRRYGLRKDGANEAALGNGATEENDQPVSG HHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
PDB accession: NA
Resolution: NA
Structure class: Unstructured
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: NA