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The map label for this gene is phoP [H]

Identifier: 158318716

GI number: 158318716

Start: 8507177

End: 8507866

Strand: Direct

Name: phoP [H]

Synonym: Franean1_6985

Alternate gene names: 158318716

Gene position: 8507177-8507866 (Clockwise)

Preceding gene: 158318714

Following gene: 158318717

Centisome position: 94.71

GC content: 74.64

Gene sequence:

>690_bases
GTGGCGACGATCCTGGTTGTCGAGGACGACCCGTACGTGCGTGCCGCGCTGGTGCGGCACCTGTCCAGCGCCGGGCACGC
GGTGCGCAGTGTCGGCGCGGCGCTCGACGCGCTGCGCGAGGTGACGCAGGTCGGCTGCGACCTCGTCGTGCTCGACCTGG
GCCTGCCCGATCTGGACGGCGCGGCCGCACTGCGGATGCTGCGCGGCGTCAGCGACGTCCCGGTGGTGGTCGCGACGGCG
CGCGGGGACGAGCCGGCGATGGTCCGGCTGCTGCACAGCGGTGCCGACGACTACCTGGTGAAACCGTTCTCGCCGGAGCA
TCTCGACGCGCGCGTCACCGCCGTGCTGCGCCGTACGAGTCCGGCCGCCGCCACCGGCCGGGTACCGGCGTTCCGGGTGG
GTGAGCTGGTGGTCGACCCCCGGCAGCGCACGGCGGTGCTGGACGGGCGGGATCTCGACCTCACCCGGCGCGAGTTCGAC
CTGCTGGCCTACCTGGCCGCCCGCCCCGGCGACGTGGTGCCGCGCCGGGAGCTGCTGGCCGCCGTGTGGCAGCAGGCGTA
CGGCGGCGACCAGACGATCGACGTCCATCTGTCGTGGCTGCGCCGCAAGCTCGGGGAGACCGCCGCCCGGCCGAAGTACC
TCCACACGGTGCGTGGCGTCGGGGTCAAGCTCGAGGCGCCTCGGCCGTGA

Upstream 100 bases:

>100_bases
ATCGTCAGGTACCGACACGTCGTCAGGTACCGACACGTCGTACCGCCGCCGCCCGAGAGGAGCCACGCCGATGACTCCGC
AGGCGACCGGGTAGCCGGGC

Downstream 100 bases:

>100_bases
GTCGGCCGACGGCACGATGCGGGCTCGGCAATGCCCAGGCGAGGGCGCGATGAGGGCACGGGTGAGAGCGCGATGAGGTG
GGCGCTCGCCAAGGTGTCGA

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 229; Mature: 228

Protein sequence:

>229_residues
MATILVVEDDPYVRAALVRHLSSAGHAVRSVGAALDALREVTQVGCDLVVLDLGLPDLDGAAALRMLRGVSDVPVVVATA
RGDEPAMVRLLHSGADDYLVKPFSPEHLDARVTAVLRRTSPAAATGRVPAFRVGELVVDPRQRTAVLDGRDLDLTRREFD
LLAYLAARPGDVVPRRELLAAVWQQAYGGDQTIDVHLSWLRRKLGETAARPKYLHTVRGVGVKLEAPRP

Sequences:

>Translated_229_residues
MATILVVEDDPYVRAALVRHLSSAGHAVRSVGAALDALREVTQVGCDLVVLDLGLPDLDGAAALRMLRGVSDVPVVVATA
RGDEPAMVRLLHSGADDYLVKPFSPEHLDARVTAVLRRTSPAAATGRVPAFRVGELVVDPRQRTAVLDGRDLDLTRREFD
LLAYLAARPGDVVPRRELLAAVWQQAYGGDQTIDVHLSWLRRKLGETAARPKYLHTVRGVGVKLEAPRP
>Mature_228_residues
ATILVVEDDPYVRAALVRHLSSAGHAVRSVGAALDALREVTQVGCDLVVLDLGLPDLDGAAALRMLRGVSDVPVVVATAR
GDEPAMVRLLHSGADDYLVKPFSPEHLDARVTAVLRRTSPAAATGRVPAFRVGELVVDPRQRTAVLDGRDLDLTRREFDL
LAYLAARPGDVVPRRELLAAVWQQAYGGDQTIDVHLSWLRRKLGETAARPKYLHTVRGVGVKLEAPRP

Specific function: Member of the two-component regulatory system phoP/phoR involved in the regulation of alkaline phosphatase genes phoA and phoB and of phosphodiesterase [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=37.9464285714286, Blast_Score=131, Evalue=5e-32,
Organism=Escherichia coli, GI1789809, Length=224, Percent_Identity=37.5, Blast_Score=127, Evalue=7e-31,
Organism=Escherichia coli, GI1786784, Length=226, Percent_Identity=37.1681415929204, Blast_Score=126, Evalue=1e-30,
Organism=Escherichia coli, GI1786599, Length=225, Percent_Identity=36, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI1786911, Length=225, Percent_Identity=36.8888888888889, Blast_Score=120, Evalue=6e-29,
Organism=Escherichia coli, GI87082012, Length=227, Percent_Identity=34.3612334801762, Blast_Score=118, Evalue=3e-28,
Organism=Escherichia coli, GI1790860, Length=225, Percent_Identity=35.5555555555556, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI1790552, Length=229, Percent_Identity=37.117903930131, Blast_Score=106, Evalue=1e-24,
Organism=Escherichia coli, GI1789402, Length=224, Percent_Identity=34.375, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI2367329, Length=172, Percent_Identity=38.953488372093, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI1787375, Length=227, Percent_Identity=34.3612334801762, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1790863, Length=227, Percent_Identity=27.3127753303965, Blast_Score=94, Evalue=6e-21,
Organism=Escherichia coli, GI1787229, Length=208, Percent_Identity=32.2115384615385, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=30.7692307692308, Blast_Score=89, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 24795; Mature: 24664

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATILVVEDDPYVRAALVRHLSSAGHAVRSVGAALDALREVTQVGCDLVVLDLGLPDLDG
CEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCH
AAALRMLRGVSDVPVVVATARGDEPAMVRLLHSGADDYLVKPFSPEHLDARVTAVLRRTS
HHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHHHHCC
PAAATGRVPAFRVGELVVDPRQRTAVLDGRDLDLTRREFDLLAYLAARPGDVVPRRELLA
CCCCCCCCCCEECCCEEECCCHHEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHH
AVWQQAYGGDQTIDVHLSWLRRKLGETAARPKYLHTVRGVGVKLEAPRP
HHHHHHCCCCCEEEHHHHHHHHHHHHHHCCCHHHHHHHCCCEEECCCCC
>Mature Secondary Structure 
ATILVVEDDPYVRAALVRHLSSAGHAVRSVGAALDALREVTQVGCDLVVLDLGLPDLDG
EEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCH
AAALRMLRGVSDVPVVVATARGDEPAMVRLLHSGADDYLVKPFSPEHLDARVTAVLRRTS
HHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHCCCCCCEECCCCCCHHHHHHHHHHHHCC
PAAATGRVPAFRVGELVVDPRQRTAVLDGRDLDLTRREFDLLAYLAARPGDVVPRRELLA
CCCCCCCCCCEECCCEEECCCHHEEEECCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHHH
AVWQQAYGGDQTIDVHLSWLRRKLGETAARPKYLHTVRGVGVKLEAPRP
HHHHHHCCCCCEEEHHHHHHHHHHHHHHCCCHHHHHHHCCCEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1454550; 3036763; 9387221; 9384377; 8045898; 3142862 [H]