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The map label for this gene is mer [H]

Identifier: 158318683

GI number: 158318683

Start: 8469594

End: 8470562

Strand: Direct

Name: mer [H]

Synonym: Franean1_6951

Alternate gene names: 158318683

Gene position: 8469594-8470562 (Clockwise)

Preceding gene: 158318681

Following gene: 158318685

Centisome position: 94.29

GC content: 72.76

Gene sequence:

>969_bases
ATGGCCGCACAGGACGGCGTGATCTCGGTCGGGTTCGTCGCCGGGGCCGATCTGAAACGGGCCGCCGTGTTGGAGGACCT
GCCGATCGACTCACTGTGGACGGGCGGGCACGTCGCCTCCCGGAACCCGTCGGGCGAGGCGATGATGAGCCTGGCCCGCC
TGTCAGCGGTGACCGAACGGGTACGCATCGGGACGTCGATCCTGCTCCTGCCGCTGTACGCACCGGCGATCGTGGCCAAG
CAGGTCGCCGACCTGGACCGGGCCACCGGCGGGCGGCTCGTCCTCGGCGTGGGCATCGGCGGCGAGTACCCGCAGGAGTT
CAGCGCCTGCCAGGTTCCGGTCCGGGAACGCGGGCGACGCACCGACGAGGCCATCGGCCTGCTCCGGCGGCTCTGGACAG
CCCAGACGATCTCCCACGACGGGCCGTTCTACCCGATGACGGACGTCCGGATCCACCCGGCGCCGGCCCAGCCCGGCGGC
CCGCCCGTCGTCGTCGCCGGCCGGAAGGAGCCGGCGATGCGCCGCGCCGCGCTGCTCGGTGACGGCTGGATGCCCTACCT
GTACTCGCCCCGCCGCTACGCGGCCTCGGCGCGGACCATCCGCCAGGCCGCGGCCGACGCCGGACGTGATCTGAGCGGAT
TCGAGTGGTACGCGTTCGTGTTCGTCAACGTCGACCCCGACGGCGACCGAGCACGCGAGGAGGCCGCGCGCACGATGGGC
GGCACCTACAACCAGGACTTCAAGACCATGGTCGACAGCGTGGCGGCGGCCGGGACGGCGGAGGAGGTCACCAGCAAGCT
CCGCGACTTCGTCGACGCCGGCGCCCGGCACTTCATCTTCATGCCCGCGCCAGGCACCGGCGACCCCGACCGCATAGTCC
ACCGTCTGCTCGACGAGGTGATCCCCCCGCTACGCGCGCACGGGAACGAGCAGGCGGCCGCCCGGGCTGGGGATGAGGCC
GCGCGCTGA

Upstream 100 bases:

>100_bases
TCGGGTCGGTTGCCTGCGGGGGGCGGTCTGCTGCACGCTCGGCCAGCCGACTCCCGCCAGTGCGCACGGCGGGGGCGGCG
CGAGCCGCGGAGGTGTTCGG

Downstream 100 bases:

>100_bases
GGCCGCACACCGCGGTGCGGTGAAAGGACGTTCCGGACGTCACCCGGCGCGGCGGGCGGAGAGGGCCGCGCGGATCATCG
GGATCTGCAGCGGCATACGC

Product: luciferase family protein

Products: NA

Alternate protein names: Coenzyme F420-dependent N(5),N(10)-methylenetetrahydromethanopterin reductase; Methylene-H(4)MPT reductase [H]

Number of amino acids: Translated: 322; Mature: 321

Protein sequence:

>322_residues
MAAQDGVISVGFVAGADLKRAAVLEDLPIDSLWTGGHVASRNPSGEAMMSLARLSAVTERVRIGTSILLLPLYAPAIVAK
QVADLDRATGGRLVLGVGIGGEYPQEFSACQVPVRERGRRTDEAIGLLRRLWTAQTISHDGPFYPMTDVRIHPAPAQPGG
PPVVVAGRKEPAMRRAALLGDGWMPYLYSPRRYAASARTIRQAAADAGRDLSGFEWYAFVFVNVDPDGDRAREEAARTMG
GTYNQDFKTMVDSVAAAGTAEEVTSKLRDFVDAGARHFIFMPAPGTGDPDRIVHRLLDEVIPPLRAHGNEQAAARAGDEA
AR

Sequences:

>Translated_322_residues
MAAQDGVISVGFVAGADLKRAAVLEDLPIDSLWTGGHVASRNPSGEAMMSLARLSAVTERVRIGTSILLLPLYAPAIVAK
QVADLDRATGGRLVLGVGIGGEYPQEFSACQVPVRERGRRTDEAIGLLRRLWTAQTISHDGPFYPMTDVRIHPAPAQPGG
PPVVVAGRKEPAMRRAALLGDGWMPYLYSPRRYAASARTIRQAAADAGRDLSGFEWYAFVFVNVDPDGDRAREEAARTMG
GTYNQDFKTMVDSVAAAGTAEEVTSKLRDFVDAGARHFIFMPAPGTGDPDRIVHRLLDEVIPPLRAHGNEQAAARAGDEA
AR
>Mature_321_residues
AAQDGVISVGFVAGADLKRAAVLEDLPIDSLWTGGHVASRNPSGEAMMSLARLSAVTERVRIGTSILLLPLYAPAIVAKQ
VADLDRATGGRLVLGVGIGGEYPQEFSACQVPVRERGRRTDEAIGLLRRLWTAQTISHDGPFYPMTDVRIHPAPAQPGGP
PVVVAGRKEPAMRRAALLGDGWMPYLYSPRRYAASARTIRQAAADAGRDLSGFEWYAFVFVNVDPDGDRAREEAARTMGG
TYNQDFKTMVDSVAAAGTAEEVTSKLRDFVDAGARHFIFMPAPGTGDPDRIVHRLLDEVIPPLRAHGNEQAAARAGDEAA
R

Specific function: Catalyzes the reversible reduction of methylene-H(4)MPT to methyl-H(4)MPT [H]

COG id: COG2141

COG function: function code C; Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mer family [H]

Homologues:

Organism=Escherichia coli, GI1787247, Length=250, Percent_Identity=27.6, Blast_Score=76, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011251
- InterPro:   IPR016048
- InterPro:   IPR019946 [H]

Pfam domain/function: PF00296 Bac_luciferase [H]

EC number: =1.5.99.11 [H]

Molecular weight: Translated: 34554; Mature: 34422

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAAQDGVISVGFVAGADLKRAAVLEDLPIDSLWTGGHVASRNPSGEAMMSLARLSAVTER
CCCCCCCEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
VRIGTSILLLPLYAPAIVAKQVADLDRATGGRLVLGVGIGGEYPQEFSACQVPVRERGRR
HHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHCCCCHHHCCCC
TDEAIGLLRRLWTAQTISHDGPFYPMTDVRIHPAPAQPGGPPVVVAGRKEPAMRRAALLG
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCEEEEECCCCHHHHHHHHHC
DGWMPYLYSPRRYAASARTIRQAAADAGRDLSGFEWYAFVFVNVDPDGDRAREEAARTMG
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHC
GTYNQDFKTMVDSVAAAGTAEEVTSKLRDFVDAGARHFIFMPAPGTGDPDRIVHRLLDEV
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHH
IPPLRAHGNEQAAARAGDEAAR
CCHHHHCCCHHHHHHCCCCCCC
>Mature Secondary Structure 
AAQDGVISVGFVAGADLKRAAVLEDLPIDSLWTGGHVASRNPSGEAMMSLARLSAVTER
CCCCCCEEEEEECCCCHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
VRIGTSILLLPLYAPAIVAKQVADLDRATGGRLVLGVGIGGEYPQEFSACQVPVRERGRR
HHHCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHCCCCHHHCCCC
TDEAIGLLRRLWTAQTISHDGPFYPMTDVRIHPAPAQPGGPPVVVAGRKEPAMRRAALLG
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEECCCCCCCCCEEEEECCCCHHHHHHHHHC
DGWMPYLYSPRRYAASARTIRQAAADAGRDLSGFEWYAFVFVNVDPDGDRAREEAARTMG
CCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHC
GTYNQDFKTMVDSVAAAGTAEEVTSKLRDFVDAGARHFIFMPAPGTGDPDRIVHRLLDEV
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHHHHHHHHH
IPPLRAHGNEQAAARAGDEAAR
CCHHHHCCCHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]