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The map label for this gene is caiD [H]

Identifier: 158318644

GI number: 158318644

Start: 8420851

End: 8421708

Strand: Direct

Name: caiD [H]

Synonym: Franean1_6912

Alternate gene names: 158318644

Gene position: 8420851-8421708 (Clockwise)

Preceding gene: 158318642

Following gene: 158318645

Centisome position: 93.75

GC content: 67.6

Gene sequence:

>858_bases
ATGGTCAAGCGGACGAGGTTCAAGGAGTACGAGGACCGGTACGCCAACTACCGGTTCGAGTTAGACGAGGACGGCATCCT
GCTCATGCAGTGCCACACCAACGGCGGCAGCCTGGTGTGGGACTGGAAGTCCCACGACGACATGGCCGACGCGTTCGCCG
ACGTCGCGGGCGACCGCGAGATCAAGGTGCTGATCCACACCGGCACCGGCGAGAACTACAACGCCAACTGGGGCACCCTC
CCCAACGGCGAGCCCCCCGAGAAGCCGGAGTACCGGCTGATGCCGGGCGACCGCGGGCTACGCAAGCTCGACGAGAAGGC
CTGGTACAACCGCAACCTGATCAACAACGTCCTCGACGTCGGCGTCCCCATGATCAGCGCGGTCAACGGCCCCTGCAACA
TCCACTCCGAGGTTCCCCTGATGGGGGACATCGTGCTCGCGTCCGAGGACGCGTACTTCCAGGACGTGTCGCACTTCCCC
CGCGGGCAGGTACCCGGCGACGGCCAGCACGTCATCTGGCCCTTCCTCGTCGGCCACAACCGCGCCCGCTACCTGCTGCT
CACCGGGAAGAAGCTCGGCGCCCAGGAGGCGCTCTCGTGGGGCGCCGTCGCCGAGGTGCTCCCGAAGGACCAGCTCCTCG
ACCGTGCCTGGGAGCTCGCGCGGGAGCTGGTGCGCAAGCCACCGCTCGTGCTGCGCTACACCCGCGACCTGTTCACCCAG
GACCTCAAGCGGGCCTTCCTGAACGAGCTCGGCCACGGCCTGGGCCGCGAGACCTACGCCCAGCGGGAGTTCTTCCCGTT
CGGCGGCGGCATGGAGCCACTGGACAGACCGTGGGACGCACAGCCCTGGTCGGATTAA

Upstream 100 bases:

>100_bases
AACATGCCCGTCCGACTATAGGACGACCTTGGATATGTGGTAACGTCACTTCCGCGAGGGAAGATCGACGTTCTCCCGGC
CGCGCCGAAGGGACATGGGG

Downstream 100 bases:

>100_bases
GAATCGACCTCGACGTCGAATCGCCGACCACTGGAGGCTGACGACATGCACGCACTGCAGGGCGTTCGAGTTCTCGACCT
GGGCACCTACCTCGCGGGGC

Product: enoyl-CoA hydratase/isomerase

Products: L-Carnitine.; L-carnitinyl-CoA [C]

Alternate protein names: Crotonobetainyl-CoA hydratase [H]

Number of amino acids: Translated: 285; Mature: 285

Protein sequence:

>285_residues
MVKRTRFKEYEDRYANYRFELDEDGILLMQCHTNGGSLVWDWKSHDDMADAFADVAGDREIKVLIHTGTGENYNANWGTL
PNGEPPEKPEYRLMPGDRGLRKLDEKAWYNRNLINNVLDVGVPMISAVNGPCNIHSEVPLMGDIVLASEDAYFQDVSHFP
RGQVPGDGQHVIWPFLVGHNRARYLLLTGKKLGAQEALSWGAVAEVLPKDQLLDRAWELARELVRKPPLVLRYTRDLFTQ
DLKRAFLNELGHGLGRETYAQREFFPFGGGMEPLDRPWDAQPWSD

Sequences:

>Translated_285_residues
MVKRTRFKEYEDRYANYRFELDEDGILLMQCHTNGGSLVWDWKSHDDMADAFADVAGDREIKVLIHTGTGENYNANWGTL
PNGEPPEKPEYRLMPGDRGLRKLDEKAWYNRNLINNVLDVGVPMISAVNGPCNIHSEVPLMGDIVLASEDAYFQDVSHFP
RGQVPGDGQHVIWPFLVGHNRARYLLLTGKKLGAQEALSWGAVAEVLPKDQLLDRAWELARELVRKPPLVLRYTRDLFTQ
DLKRAFLNELGHGLGRETYAQREFFPFGGGMEPLDRPWDAQPWSD
>Mature_285_residues
MVKRTRFKEYEDRYANYRFELDEDGILLMQCHTNGGSLVWDWKSHDDMADAFADVAGDREIKVLIHTGTGENYNANWGTL
PNGEPPEKPEYRLMPGDRGLRKLDEKAWYNRNLINNVLDVGVPMISAVNGPCNIHSEVPLMGDIVLASEDAYFQDVSHFP
RGQVPGDGQHVIWPFLVGHNRARYLLLTGKKLGAQEALSWGAVAEVLPKDQLLDRAWELARELVRKPPLVLRYTRDLFTQ
DLKRAFLNELGHGLGRETYAQREFFPFGGGMEPLDRPWDAQPWSD

Specific function: Catalyzes the reversible dehydration of L-carnitinyl-CoA to crotonobetainyl-CoA [H]

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Escherichia coli, GI221142681, Length=200, Percent_Identity=29, Blast_Score=79, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI25145438, Length=136, Percent_Identity=36.0294117647059, Blast_Score=74, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022852
- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: 4.2.1.- [C]

Molecular weight: Translated: 32535; Mature: 32535

Theoretical pI: Translated: 5.23; Mature: 5.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVKRTRFKEYEDRYANYRFELDEDGILLMQCHTNGGSLVWDWKSHDDMADAFADVAGDRE
CCCCCHHHHHHHHHCCEEEEECCCCEEEEEEECCCCCEEEECCCCCHHHHHHHHHCCCCE
IKVLIHTGTGENYNANWGTLPNGEPPEKPEYRLMPGDRGLRKLDEKAWYNRNLINNVLDV
EEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
GVPMISAVNGPCNIHSEVPLMGDIVLASEDAYFQDVSHFPRGQVPGDGQHVIWPFLVGHN
CCHHHHHCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHCCCCCCCCCCCEEEEEEEECCC
RARYLLLTGKKLGAQEALSWGAVAEVLPKDQLLDRAWELARELVRKPPLVLRYTRDLFTQ
CEEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHH
DLKRAFLNELGHGLGRETYAQREFFPFGGGMEPLDRPWDAQPWSD
HHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MVKRTRFKEYEDRYANYRFELDEDGILLMQCHTNGGSLVWDWKSHDDMADAFADVAGDRE
CCCCCHHHHHHHHHCCEEEEECCCCEEEEEEECCCCCEEEECCCCCHHHHHHHHHCCCCE
IKVLIHTGTGENYNANWGTLPNGEPPEKPEYRLMPGDRGLRKLDEKAWYNRNLINNVLDV
EEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHH
GVPMISAVNGPCNIHSEVPLMGDIVLASEDAYFQDVSHFPRGQVPGDGQHVIWPFLVGHN
CCHHHHHCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHCCCCCCCCCCCEEEEEEEECCC
RARYLLLTGKKLGAQEALSWGAVAEVLPKDQLLDRAWELARELVRKPPLVLRYTRDLFTQ
CEEEEEEECCCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEHHHHHHHH
DLKRAFLNELGHGLGRETYAQREFFPFGGGMEPLDRPWDAQPWSD
HHHHHHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: D-Carnitine; D-carnitinyl-CoA [C]

Specific reaction: D-Carnitine = L-Carnitine. D-carnitinyl-CoA = L-carnitinyl-CoA [C]

General reaction: Isomerases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA