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The map label for this gene is tcmA [H]

Identifier: 158318591

GI number: 158318591

Start: 8361685

End: 8362854

Strand: Reverse

Name: tcmA [H]

Synonym: Franean1_6859

Alternate gene names: 158318591

Gene position: 8362854-8361685 (Counterclockwise)

Preceding gene: 158318594

Following gene: 158318585

Centisome position: 93.11

GC content: 71.28

Gene sequence:

>1170_bases
GTGGGCGATGTCCCTGATGGGCGCGCTCGCCGTCGGCCCGCTGATCGCGGGCGTGCTGCTCGATCACGTCGGCTGGCGCT
GGATCACCTGCCGTCGATCCCCGTCGCGCTGCTGGCGCTCGTGGTCGGGGCGACGACGCTGTCCGACTCACGGGCCGCGG
CGCACGGTCGCCACCTGGACTGGCCCGGCCAGATCACGGCCGCCGTGGCGATCATCGGACTGGTGTACGGAGTCATCGAG
GGCGGAGCCGGGTCCTTCACCGAGGCGCGGGTCGTCGTTGCGCTTGCCGTGGCCGTTGTCGCCGGTGCCGCCTTCGTCAT
GGTCGAACGGCGCAGCACCAGCCCGATGCTCGACCTGCGGCTTTTCCGCAGCCCGGGGTTCACCGCCACAACGCTCGTCG
CGATGATCAGCTTCCTGGGTCTGATCGGCTTCTTCTTCGTGCTCAGCCTCTATTTCGGCATGGTGCAGCAGCTCGACACG
CTCCAGGCAGGCTGGCGGCTGCTGATGGTGACGCTGCCGGCGCTTCTCGTCGGCGGCCCGGTCGGACACCTCCTCCACAG
AACGTCCGCCCGGATCCTGATCACCGGTGGGCTGCTCGTGGTAACCGGTTCGTTGGCGTCGCTCCTCACGGTGGACGCGG
ACACCTCGTTCGTCTCGATCGCCTGGCGGCTGGTCCTGATGGGGCTGGGTATGGGCACGGTCATCACGCCGATGACGGCC
ACCGCCGTCGCCTCCGTGCCCTACCCGCTGGCGGGGATGGCGGCGGCGGGTAACAACGCCTTCCGACAGGTCGGTGGCGC
ACTCGGCCCCGCGGTCCTCGGCACGCTGCTCACCACCCGCGCGTTGGACACCCTCCCGGGCCATCTCGCCGACGCCGGTC
TCCCGACCGCGGATCAGCAGCGAGCGGTCGCCCTGGCCGAGGCGGGCGGACTGAACGCCGTTGCCGCGAATGTCGATGCG
GGCTCCGCCCGGGTCATGGCCGCGCTGGGAGACTCCTTCCTCGACGGCCTGCACCTGTGCCTGCTGGTGGCCGCGGTGCT
CACCCTGATCGCGGCCGTGGTCGCCCTCGTAATGCTGGGTCGCCCGAGCCCCGCGTCGATCGGCACGGCGCAGCGGACAG
GCCCCGGCAGCGAACCCGTCCGGGAGACCGTGCGGAGCGCGCGTCCCTGA

Upstream 100 bases:

>100_bases
CGTTCTCGGGCGTGGGTGCGGCGGCGCTGCTGCCCACCACGCTGGCACTGATCAGCGACGCGGTCCCGGACTTCCGGGAG
CGGGGCAGGTTCATCGGCAT

Downstream 100 bases:

>100_bases
TCAACCGGCCGGCGGCTCCGGTGCCCGGGGTCAGCCGACCGGCGCGGAACGGGGGCCGGGGGTGAAGGTGATGGGGACGT
GCAGGGGCGCCCGGGTGAGG

Product: putative transmembrane efflux protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 388

Protein sequence:

>389_residues
MGDVPDGRARRRPADRGRAARSRRLALDHLPSIPVALLALVVGATTLSDSRAAAHGRHLDWPGQITAAVAIIGLVYGVIE
GGAGSFTEARVVVALAVAVVAGAAFVMVERRSTSPMLDLRLFRSPGFTATTLVAMISFLGLIGFFFVLSLYFGMVQQLDT
LQAGWRLLMVTLPALLVGGPVGHLLHRTSARILITGGLLVVTGSLASLLTVDADTSFVSIAWRLVLMGLGMGTVITPMTA
TAVASVPYPLAGMAAAGNNAFRQVGGALGPAVLGTLLTTRALDTLPGHLADAGLPTADQQRAVALAEAGGLNAVAANVDA
GSARVMAALGDSFLDGLHLCLLVAAVLTLIAAVVALVMLGRPSPASIGTAQRTGPGSEPVRETVRSARP

Sequences:

>Translated_389_residues
MGDVPDGRARRRPADRGRAARSRRLALDHLPSIPVALLALVVGATTLSDSRAAAHGRHLDWPGQITAAVAIIGLVYGVIE
GGAGSFTEARVVVALAVAVVAGAAFVMVERRSTSPMLDLRLFRSPGFTATTLVAMISFLGLIGFFFVLSLYFGMVQQLDT
LQAGWRLLMVTLPALLVGGPVGHLLHRTSARILITGGLLVVTGSLASLLTVDADTSFVSIAWRLVLMGLGMGTVITPMTA
TAVASVPYPLAGMAAAGNNAFRQVGGALGPAVLGTLLTTRALDTLPGHLADAGLPTADQQRAVALAEAGGLNAVAANVDA
GSARVMAALGDSFLDGLHLCLLVAAVLTLIAAVVALVMLGRPSPASIGTAQRTGPGSEPVRETVRSARP
>Mature_388_residues
GDVPDGRARRRPADRGRAARSRRLALDHLPSIPVALLALVVGATTLSDSRAAAHGRHLDWPGQITAAVAIIGLVYGVIEG
GAGSFTEARVVVALAVAVVAGAAFVMVERRSTSPMLDLRLFRSPGFTATTLVAMISFLGLIGFFFVLSLYFGMVQQLDTL
QAGWRLLMVTLPALLVGGPVGHLLHRTSARILITGGLLVVTGSLASLLTVDADTSFVSIAWRLVLMGLGMGTVITPMTAT
AVASVPYPLAGMAAAGNNAFRQVGGALGPAVLGTLLTTRALDTLPGHLADAGLPTADQQRAVALAEAGGLNAVAANVDAG
SARVMAALGDSFLDGLHLCLLVAAVLTLIAAVVALVMLGRPSPASIGTAQRTGPGSEPVRETVRSARP

Specific function: Resistance to tetracenomycin C by an active tetracenomycin C efflux system which is probably energized by transmembrane electrochemical gradients [H]

COG id: COG0477

COG function: function code GEPR; Permeases of the major facilitator superfamily

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. EmrB family [H]

Homologues:

Organism=Escherichia coli, GI87081983, Length=252, Percent_Identity=25.7936507936508, Blast_Score=63, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004638
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 39802; Mature: 39671

Theoretical pI: Translated: 11.40; Mature: 11.40

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDVPDGRARRRPADRGRAARSRRLALDHLPSIPVALLALVVGATTLSDSRAAAHGRHLD
CCCCCCCHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCCCCC
WPGQITAAVAIIGLVYGVIEGGAGSFTEARVVVALAVAVVAGAAFVMVERRSTSPMLDLR
CCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHH
LFRSPGFTATTLVAMISFLGLIGFFFVLSLYFGMVQQLDTLQAGWRLLMVTLPALLVGGP
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
VGHLLHRTSARILITGGLLVVTGSLASLLTVDADTSFVSIAWRLVLMGLGMGTVITPMTA
HHHHHHHCCCEEEEECCHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHCCCCHHHHHHHH
TAVASVPYPLAGMAAAGNNAFRQVGGALGPAVLGTLLTTRALDTLPGHLADAGLPTADQQ
HHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCHH
RAVALAEAGGLNAVAANVDAGSARVMAALGDSFLDGLHLCLLVAAVLTLIAAVVALVMLG
HHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RPSPASIGTAQRTGPGSEPVRETVRSARP
CCCCCCCCCCCCCCCCCHHHHHHHHCCCC
>Mature Secondary Structure 
GDVPDGRARRRPADRGRAARSRRLALDHLPSIPVALLALVVGATTLSDSRAAAHGRHLD
CCCCCCHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCCCCC
WPGQITAAVAIIGLVYGVIEGGAGSFTEARVVVALAVAVVAGAAFVMVERRSTSPMLDLR
CCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHH
LFRSPGFTATTLVAMISFLGLIGFFFVLSLYFGMVQQLDTLQAGWRLLMVTLPALLVGGP
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCH
VGHLLHRTSARILITGGLLVVTGSLASLLTVDADTSFVSIAWRLVLMGLGMGTVITPMTA
HHHHHHHCCCEEEEECCHHHHHHHHHHHHEECCCCHHHHHHHHHHHHHCCCCHHHHHHHH
TAVASVPYPLAGMAAAGNNAFRQVGGALGPAVLGTLLTTRALDTLPGHLADAGLPTADQQ
HHHHCCCCCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCCCCCCCHH
RAVALAEAGGLNAVAANVDAGSARVMAALGDSFLDGLHLCLLVAAVLTLIAAVVALVMLG
HHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
RPSPASIGTAQRTGPGSEPVRETVRSARP
CCCCCCCCCCCCCCCCCHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1592819 [H]