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The map label for this gene is mmgC [H]

Identifier: 158318579

GI number: 158318579

Start: 8347358

End: 8348554

Strand: Reverse

Name: mmgC [H]

Synonym: Franean1_6847

Alternate gene names: 158318579

Gene position: 8348554-8347358 (Counterclockwise)

Preceding gene: 158318580

Following gene: 158318578

Centisome position: 92.95

GC content: 76.69

Gene sequence:

>1197_bases
ATGAGCGCCGGTCCGGGCACCGCGGGCGCGCCGCAGGACGCGAGCACGCCGCAGGATGTGGACGACCTGCGCGAGCTGCA
CCGCGAGCTGCGTGACGTGGCGCGCGACATGCTCCGCAAGACCACCGGCCGCACCGGCGACGACGAGGCGCCCGTCCCGG
TGGACTGGTCGCTGCTGGCCGGCTCCGGCTGGCTGGGGCTGGAGGTGCCCGAGGAGCTCGACGGCGCCGGCGCGACCTTC
GCCGAGGTCGCGGTCGTGCTGCACGAGATCGGCCGGGCCGCCGCCAGCAGCGGTTACCTCGGCTCGGCCGTGCTCGGGGT
CGGCGCGCTGCGCCTGCTCGAGCCCGGCGCCGGCCGGGACGAACTGCTGGCCGCGGTGGCCGCCGGCGAGCAGCGCCTCG
CCGTCGCGCTGCCGGCCGGTGACGACGTCACCATCCCGTTCCACGTCCGCCCGGCGACGCCCGGCGACGCACCCGGTGCC
GGCGGGGGCGCGCGGGTCGACGGCGCCGCCGGCTTCGTGCTCGACGCGGCCGAGGCCGACCAGCTGCTCCTGGTGGCCCT
CGACCCGGCGGGCGTGCCCGTGGTGGTGCGGGTCCGCCCGGACGACCCCGGGGTCACCGTCACCGGGCAGCCGGTCGTCG
ACGAGACCCGCAGCCTGGGCATTGTCACCGTGGACGGCGCGGTGGTCGACGCCGGGTCAGTGTGGCAGTTCGGAACGGAT
CCGCAGGAGTCCGTCCGTCGCCTGCTGGACCGCGCGGCGCTGGCCGTGGCCTGCGACTGCCTAGGCCTGGCCGAGGCGAT
GCTCGAGGCCACCGTCGACTACGCCGGCACCCGGCGGCAGTTCGGACGTCCGATCGGGTCGTTCCAGGCGGTGAAGCACG
CCTGCGCCGACATGTTCGTGCGGATCTCGGTGGGCCGGGAGCTGCTGGCGGCGGGGGTGGCCGCGGTGGCGTCCGACGAC
CCGCAGGCCGGGGTGGCCGTGTCGCGGGCGAAGTCCTACGTCTGTGTCGCGGCCGTCGACGTCGCCGGCCGGGCCATGCA
GCTTCACGGCGGCATCGGGTACACCTGGGAGGGCGGCGTCCACGTATACCTCAAGCGGGCGCTGCTGGGCCGGGCGCTGT
TCGGCGCGCCCGCCGCGCACCGTGCCCGCCTCGCCGCGCGGTTCGCCGAGTCGGCGGACGACCCGCTCACCGAGTAG

Upstream 100 bases:

>100_bases
GTTCCTGGGAGTGGACGATCCCCGGCGGCACGAGCGAGATCCAGCGCACGATCATCGGTGAGCGCGGGCTCGGCCTGCCC
CGTGAGCCGGTGGTGCCGGC

Downstream 100 bases:

>100_bases
ACCGCTCACCGCGTAGGCGGACTGGCGGGCCTGGCGGCCCGGCCGGCGGGCTGGTCCCCGCGCCGGCCGGGCTCGCCGCC
AGGTCCGCCCGCGGCGTTGG

Product: acyl-CoA dehydrogenase domain-containing protein

Products: gamma-butyrobetaine; Acceptor; gamma-butyrobetainyl-CoA [C]

Alternate protein names: NA

Number of amino acids: Translated: 398; Mature: 397

Protein sequence:

>398_residues
MSAGPGTAGAPQDASTPQDVDDLRELHRELRDVARDMLRKTTGRTGDDEAPVPVDWSLLAGSGWLGLEVPEELDGAGATF
AEVAVVLHEIGRAAASSGYLGSAVLGVGALRLLEPGAGRDELLAAVAAGEQRLAVALPAGDDVTIPFHVRPATPGDAPGA
GGGARVDGAAGFVLDAAEADQLLLVALDPAGVPVVVRVRPDDPGVTVTGQPVVDETRSLGIVTVDGAVVDAGSVWQFGTD
PQESVRRLLDRAALAVACDCLGLAEAMLEATVDYAGTRRQFGRPIGSFQAVKHACADMFVRISVGRELLAAGVAAVASDD
PQAGVAVSRAKSYVCVAAVDVAGRAMQLHGGIGYTWEGGVHVYLKRALLGRALFGAPAAHRARLAARFAESADDPLTE

Sequences:

>Translated_398_residues
MSAGPGTAGAPQDASTPQDVDDLRELHRELRDVARDMLRKTTGRTGDDEAPVPVDWSLLAGSGWLGLEVPEELDGAGATF
AEVAVVLHEIGRAAASSGYLGSAVLGVGALRLLEPGAGRDELLAAVAAGEQRLAVALPAGDDVTIPFHVRPATPGDAPGA
GGGARVDGAAGFVLDAAEADQLLLVALDPAGVPVVVRVRPDDPGVTVTGQPVVDETRSLGIVTVDGAVVDAGSVWQFGTD
PQESVRRLLDRAALAVACDCLGLAEAMLEATVDYAGTRRQFGRPIGSFQAVKHACADMFVRISVGRELLAAGVAAVASDD
PQAGVAVSRAKSYVCVAAVDVAGRAMQLHGGIGYTWEGGVHVYLKRALLGRALFGAPAAHRARLAARFAESADDPLTE
>Mature_397_residues
SAGPGTAGAPQDASTPQDVDDLRELHRELRDVARDMLRKTTGRTGDDEAPVPVDWSLLAGSGWLGLEVPEELDGAGATFA
EVAVVLHEIGRAAASSGYLGSAVLGVGALRLLEPGAGRDELLAAVAAGEQRLAVALPAGDDVTIPFHVRPATPGDAPGAG
GGARVDGAAGFVLDAAEADQLLLVALDPAGVPVVVRVRPDDPGVTVTGQPVVDETRSLGIVTVDGAVVDAGSVWQFGTDP
QESVRRLLDRAALAVACDCLGLAEAMLEATVDYAGTRRQFGRPIGSFQAVKHACADMFVRISVGRELLAAGVAAVASDDP
QAGVAVSRAKSYVCVAAVDVAGRAMQLHGGIGYTWEGGVHVYLKRALLGRALFGAPAAHRARLAARFAESADDPLTE

Specific function: Catalyzes the reduction of crotonobetainyl-CoA to gamma-butyrobetainyl-CoA. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=366, Percent_Identity=25.6830601092896, Blast_Score=80, Evalue=3e-15,
Organism=Homo sapiens, GI226958412, Length=362, Percent_Identity=25.1381215469613, Blast_Score=70, Evalue=5e-12,
Organism=Homo sapiens, GI226958414, Length=320, Percent_Identity=26.5625, Blast_Score=68, Evalue=1e-11,
Organism=Escherichia coli, GI1786223, Length=306, Percent_Identity=26.797385620915, Blast_Score=68, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17538396, Length=319, Percent_Identity=27.2727272727273, Blast_Score=73, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: 1.3.99.- [C]

Molecular weight: Translated: 40747; Mature: 40616

Theoretical pI: Translated: 4.52; Mature: 4.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAGPGTAGAPQDASTPQDVDDLRELHRELRDVARDMLRKTTGRTGDDEAPVPVDWSLLA
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEE
GSGWLGLEVPEELDGAGATFAEVAVVLHEIGRAAASSGYLGSAVLGVGALRLLEPGAGRD
CCCEECCCCCHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHH
ELLAAVAAGEQRLAVALPAGDDVTIPFHVRPATPGDAPGAGGGARVDGAAGFVLDAAEAD
HHHHHHHCCCCEEEEEECCCCCEEEEEEEECCCCCCCCCCCCCCEECCCCCEEEECCCCC
QLLLVALDPAGVPVVVRVRPDDPGVTVTGQPVVDETRSLGIVTVDGAVVDAGSVWQFGTD
CEEEEEECCCCCEEEEEEECCCCCEEEECCCHHHHHHCCCEEEECCEEECCCCCCCCCCC
PQESVRRLLDRAALAVACDCLGLAEAMLEATVDYAGTRRQFGRPIGSFQAVKHACADMFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHHHHHH
RISVGRELLAAGVAAVASDDPQAGVAVSRAKSYVCVAAVDVAGRAMQLHGGIGYTWEGGV
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCEEEEEEECCCCCEEEECCCCCEEECCCH
HVYLKRALLGRALFGAPAAHRARLAARFAESADDPLTE
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SAGPGTAGAPQDASTPQDVDDLRELHRELRDVARDMLRKTTGRTGDDEAPVPVDWSLLA
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEE
GSGWLGLEVPEELDGAGATFAEVAVVLHEIGRAAASSGYLGSAVLGVGALRLLEPGAGRD
CCCEECCCCCHHCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCHH
ELLAAVAAGEQRLAVALPAGDDVTIPFHVRPATPGDAPGAGGGARVDGAAGFVLDAAEAD
HHHHHHHCCCCEEEEEECCCCCEEEEEEEECCCCCCCCCCCCCCEECCCCCEEEECCCCC
QLLLVALDPAGVPVVVRVRPDDPGVTVTGQPVVDETRSLGIVTVDGAVVDAGSVWQFGTD
CEEEEEECCCCCEEEEEEECCCCCEEEECCCHHHHHHCCCEEEECCEEECCCCCCCCCCC
PQESVRRLLDRAALAVACDCLGLAEAMLEATVDYAGTRRQFGRPIGSFQAVKHACADMFV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHCCCCHHHHHHHHHHHHHHH
RISVGRELLAAGVAAVASDDPQAGVAVSRAKSYVCVAAVDVAGRAMQLHGGIGYTWEGGV
HHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCCEEEEEEECCCCCEEEECCCCCEEECCCH
HVYLKRALLGRALFGAPAAHRARLAARFAESADDPLTE
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: crotono-betaine; reduced acceptor; crotonobetainyl-CoA [C]

Specific reaction: reduced acceptor + crotono-betaine = Acceptor + gamma-butyrobetaine reduced acceptor + crotonobetainyl-CoA = Acceptor + gamma-butyrobetainyl-CoA [C]

General reaction: Oxidoreductases; Acting on the CH-CH group of donors; With other acceptors [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8759838; 8969508; 9384377 [H]