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The map label for this gene is yciK [C]

Identifier: 158318547

GI number: 158318547

Start: 8304291

End: 8305229

Strand: Direct

Name: yciK [C]

Synonym: Franean1_6815

Alternate gene names: 158318547

Gene position: 8304291-8305229 (Clockwise)

Preceding gene: 158318546

Following gene: 158318548

Centisome position: 92.45

GC content: 67.63

Gene sequence:

>939_bases
ATGGCGGAAGCGCCTGAGCGGCGGCGTTGGAGTGCGGCCGACGTTCCCGACCTGAACGGGCGGACGGCCGTCGTCACCGG
CGCGAACTCCGGAATCGGCTTCGAGGCCGCCAAGCTGCTCGCCGGGCGCGGCGCGACAGTGGTGATGGCCTGCCGTAACC
CGGTCAAGGCACAGGACGCCCTGGACACCATCCGGATCGCCGTACCCGAGGCGGACGTCTCAGTACTGCAGATGGATCTC
AGCTCGCTCACCTCGGTCCGCAAGGCCGCAGACGCGCTGGTCACGGAGCGCCCCGTCATCGACCTGCTCATCAACAACGC
GGGCGTCATGTTACTGCCCCAGGGCAAGACCGAGGACGGCTTCGAACAGCACTTCGGTATCAACCACCTCGGCCACTTCG
CCTTTACCGGGCTCGTCCTGGAAGCCGTGACGGCCTCCGACGCCGGCCGCATAGTGACGGTCAGCAGCAACGGGCACCGG
ATGGGAAAGATCGACTTCGACGACCTCGACCTGGCCCAGAAGTACCGGCCGTTCCGGGCCTACGCCCGGTCGAAACTCGC
GAACCTGCTGTTCACCTATGAGCTGCAGCGCCGGCTGACGGCGGCGGGAGGATCGGCACGGTCCGTCGCCGCGCATCCTG
GTGGCGCGAACACGGAGGTCGGGGGCAACCCCAGCCCGGTCCAGCGGAAACTCAAGAAGGTCGTCGACCACATCCCCAAC
CCCATCGTCCACTCGGCGTTCAAAGGCTCCCTGCCCCTTCTGCGCGCGGCGGTTGATCCATCGACGAGGGGTGGCGAGTA
CTACGGGCCGTCCGGGCTGCTGAAGATGACCGGCCACCCGGTGCTGGTCACCTCCAACGCCGCGTCGCGGGACACCGGGA
CCGCCGAACGTCTGTGGGAACTGTCCGAGCGGCTGACCATGGTGACCTACCCGCTCTGA

Upstream 100 bases:

>100_bases
GACCAGCGCCTGTAGTGTGCTGTCAGTGGTCTCGATATGGCCACGGGTTTCACATCAGATGGGCGGAGATCCTCGCCCTG
TATCGATCGCGGAGGTCGTC

Downstream 100 bases:

>100_bases
GCGGCGCCGCGGCACCCACCGGCAGCGGGCGACGGCGCGGCGGGCCCACTTCGCCAGGTTGCGACGTTTTTATACTTGGT
ATAAATTCGTAGCAGCCTAC

Product: short-chain dehydrogenase/reductase SDR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 312; Mature: 311

Protein sequence:

>312_residues
MAEAPERRRWSAADVPDLNGRTAVVTGANSGIGFEAAKLLAGRGATVVMACRNPVKAQDALDTIRIAVPEADVSVLQMDL
SSLTSVRKAADALVTERPVIDLLINNAGVMLLPQGKTEDGFEQHFGINHLGHFAFTGLVLEAVTASDAGRIVTVSSNGHR
MGKIDFDDLDLAQKYRPFRAYARSKLANLLFTYELQRRLTAAGGSARSVAAHPGGANTEVGGNPSPVQRKLKKVVDHIPN
PIVHSAFKGSLPLLRAAVDPSTRGGEYYGPSGLLKMTGHPVLVTSNAASRDTGTAERLWELSERLTMVTYPL

Sequences:

>Translated_312_residues
MAEAPERRRWSAADVPDLNGRTAVVTGANSGIGFEAAKLLAGRGATVVMACRNPVKAQDALDTIRIAVPEADVSVLQMDL
SSLTSVRKAADALVTERPVIDLLINNAGVMLLPQGKTEDGFEQHFGINHLGHFAFTGLVLEAVTASDAGRIVTVSSNGHR
MGKIDFDDLDLAQKYRPFRAYARSKLANLLFTYELQRRLTAAGGSARSVAAHPGGANTEVGGNPSPVQRKLKKVVDHIPN
PIVHSAFKGSLPLLRAAVDPSTRGGEYYGPSGLLKMTGHPVLVTSNAASRDTGTAERLWELSERLTMVTYPL
>Mature_311_residues
AEAPERRRWSAADVPDLNGRTAVVTGANSGIGFEAAKLLAGRGATVVMACRNPVKAQDALDTIRIAVPEADVSVLQMDLS
SLTSVRKAADALVTERPVIDLLINNAGVMLLPQGKTEDGFEQHFGINHLGHFAFTGLVLEAVTASDAGRIVTVSSNGHRM
GKIDFDDLDLAQKYRPFRAYARSKLANLLFTYELQRRLTAAGGSARSVAAHPGGANTEVGGNPSPVQRKLKKVVDHIPNP
IVHSAFKGSLPLLRAAVDPSTRGGEYYGPSGLLKMTGHPVLVTSNAASRDTGTAERLWELSERLTMVTYPL

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI186928839, Length=313, Percent_Identity=39.297124600639, Blast_Score=186, Evalue=3e-47,
Organism=Homo sapiens, GI225579078, Length=212, Percent_Identity=46.6981132075472, Blast_Score=173, Evalue=2e-43,
Organism=Homo sapiens, GI166795268, Length=303, Percent_Identity=39.6039603960396, Blast_Score=169, Evalue=2e-42,
Organism=Homo sapiens, GI10190746, Length=301, Percent_Identity=36.5448504983389, Blast_Score=168, Evalue=7e-42,
Organism=Homo sapiens, GI193804850, Length=258, Percent_Identity=39.5348837209302, Blast_Score=162, Evalue=4e-40,
Organism=Homo sapiens, GI7706523, Length=299, Percent_Identity=35.4515050167224, Blast_Score=156, Evalue=2e-38,
Organism=Homo sapiens, GI146231950, Length=296, Percent_Identity=37.1621621621622, Blast_Score=148, Evalue=7e-36,
Organism=Homo sapiens, GI19923931, Length=167, Percent_Identity=47.3053892215569, Blast_Score=135, Evalue=3e-32,
Organism=Escherichia coli, GI1787526, Length=233, Percent_Identity=29.1845493562232, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17532805, Length=305, Percent_Identity=35.0819672131148, Blast_Score=146, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI193207620, Length=301, Percent_Identity=31.8936877076412, Blast_Score=136, Evalue=1e-32,
Organism=Caenorhabditis elegans, GI17558006, Length=208, Percent_Identity=38.4615384615385, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI17532791, Length=210, Percent_Identity=37.6190476190476, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI71992402, Length=264, Percent_Identity=31.4393939393939, Blast_Score=111, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI32565532, Length=207, Percent_Identity=34.2995169082126, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17535059, Length=301, Percent_Identity=28.5714285714286, Blast_Score=100, Evalue=7e-22,
Organism=Caenorhabditis elegans, GI72001364, Length=258, Percent_Identity=33.3333333333333, Blast_Score=99, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI17505416, Length=230, Percent_Identity=29.5652173913043, Blast_Score=99, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI115533174, Length=291, Percent_Identity=24.7422680412371, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI115533172, Length=291, Percent_Identity=24.7422680412371, Blast_Score=69, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6324820, Length=295, Percent_Identity=27.4576271186441, Blast_Score=86, Evalue=7e-18,
Organism=Drosophila melanogaster, GI28573296, Length=290, Percent_Identity=39.3103448275862, Blast_Score=173, Evalue=1e-43,
Organism=Drosophila melanogaster, GI22024069, Length=291, Percent_Identity=39.1752577319588, Blast_Score=170, Evalue=1e-42,
Organism=Drosophila melanogaster, GI161076371, Length=298, Percent_Identity=37.9194630872483, Blast_Score=170, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24586328, Length=290, Percent_Identity=37.9310344827586, Blast_Score=168, Evalue=4e-42,
Organism=Drosophila melanogaster, GI19921754, Length=296, Percent_Identity=38.1756756756757, Blast_Score=162, Evalue=2e-40,
Organism=Drosophila melanogaster, GI45554248, Length=293, Percent_Identity=37.8839590443686, Blast_Score=159, Evalue=3e-39,
Organism=Drosophila melanogaster, GI24640117, Length=293, Percent_Identity=37.8839590443686, Blast_Score=159, Evalue=3e-39,
Organism=Drosophila melanogaster, GI20129347, Length=297, Percent_Identity=34.006734006734, Blast_Score=137, Evalue=9e-33,
Organism=Drosophila melanogaster, GI24656154, Length=318, Percent_Identity=32.7044025157233, Blast_Score=135, Evalue=4e-32,
Organism=Drosophila melanogaster, GI19922628, Length=318, Percent_Identity=32.7044025157233, Blast_Score=135, Evalue=4e-32,
Organism=Drosophila melanogaster, GI45553409, Length=294, Percent_Identity=33.3333333333333, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24647948, Length=294, Percent_Identity=33.3333333333333, Blast_Score=133, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24647946, Length=294, Percent_Identity=33.3333333333333, Blast_Score=132, Evalue=2e-31,
Organism=Drosophila melanogaster, GI24647931, Length=319, Percent_Identity=34.4827586206897, Blast_Score=125, Evalue=3e-29,
Organism=Drosophila melanogaster, GI24643142, Length=142, Percent_Identity=35.9154929577465, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 33300; Mature: 33169

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEAPERRRWSAADVPDLNGRTAVVTGANSGIGFEAAKLLAGRGATVVMACRNPVKAQDA
CCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCEEEEECCCCCCHHHH
LDTIRIAVPEADVSVLQMDLSSLTSVRKAADALVTERPVIDLLINNAGVMLLPQGKTEDG
HHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEECCCCCCC
FEQHFGINHLGHFAFTGLVLEAVTASDAGRIVTVSSNGHRMGKIDFDDLDLAQKYRPFRA
HHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEECCCCCCHHHHHHHCCHHHH
YARSKLANLLFTYELQRRLTAAGGSARSVAAHPGGANTEVGGNPSPVQRKLKKVVDHIPN
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCC
PIVHSAFKGSLPLLRAAVDPSTRGGEYYGPSGLLKMTGHPVLVTSNAASRDTGTAERLWE
HHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCEEEECCCEEEEECCCCCCCCCHHHHHHH
LSERLTMVTYPL
HHHCEEEEEECC
>Mature Secondary Structure 
AEAPERRRWSAADVPDLNGRTAVVTGANSGIGFEAAKLLAGRGATVVMACRNPVKAQDA
CCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHCCCCEEEEECCCCCCHHHH
LDTIRIAVPEADVSVLQMDLSSLTSVRKAADALVTERPVIDLLINNAGVMLLPQGKTEDG
HHEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCCEEEEECCCCCCC
FEQHFGINHLGHFAFTGLVLEAVTASDAGRIVTVSSNGHRMGKIDFDDLDLAQKYRPFRA
HHHHCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCEECCCCCCHHHHHHHCCHHHH
YARSKLANLLFTYELQRRLTAAGGSARSVAAHPGGANTEVGGNPSPVQRKLKKVVDHIPN
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCC
PIVHSAFKGSLPLLRAAVDPSTRGGEYYGPSGLLKMTGHPVLVTSNAASRDTGTAERLWE
HHHHHHHCCCCHHHHHHCCCCCCCCCCCCCCCEEEECCCEEEEECCCCCCCCCHHHHHHH
LSERLTMVTYPL
HHHCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on the CH-OH group of donors; With NAD or NADP as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8383668 [H]