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The map label for this gene is katA [H]

Identifier: 158318523

GI number: 158318523

Start: 8272731

End: 8274254

Strand: Direct

Name: katA [H]

Synonym: Franean1_6791

Alternate gene names: 158318523

Gene position: 8272731-8274254 (Clockwise)

Preceding gene: 158318521

Following gene: 158318530

Centisome position: 92.1

GC content: 66.08

Gene sequence:

>1524_bases
GTGACCGTTCAGAAGCCTCGTCCGACGACGACCGATGCCGGAATACCCGTCGCCAGCGATGAGCACTCGCTGTCCGTGGG
GCCGGACGGCCCGCTGCTGCTGCAGGATCACTACCTGATCGAGCAGATGGCGAACTTCAACCGGGAACGCATCCCGGAGC
GTCAGCCGCACGCGAAGGGCGGTGGCGCGTTCGGCACCTTCCAGGTCACCCAGGACATGAGCGCGTTCACCCGGGCCGCG
GTGTTCCAGCCCGGTACCGAGACGGATGTGATCATTCGGTTCTCGACGGTGGCCGGGGAGCGCGGCAGCCCCGACACCTG
GCGCGACCCACGCGGTTTCGCGGTCAAGTTCTACACCAGCGAGGGCAATCTCGACATCGTCGGGAACAACACGCCGGTCT
TCTTCATCAGGGATCCGCTGAAGTTCCAGCACTTCATCCGGTCCCAGAAGCGCCGGGCCGACAACAACCTGCGTGACCAC
GACATGCAGTGGGACTTCTGGACGCTGTCACCGGAGTCCGCGCACCAGGTCACGTGGCTGATGGGTGACCGCGGCATTCC
GCGCACCTGGCGACACATGAACGGATACTCCAGCCACACGTACATGTGGATCAACGCCGCCGGCGAGCGGTTCTGGGTGA
AGTACCACTTCAAGACCGATCAGGGCATCGAGTTCTTCACCCAGGACGAGGGTGACCAGATGGCCTCGGTAGACACCGAC
TACCACCAGCGCGACCTCTTCGAGCACATCGCCGCCGGGGACTTCCCGAGCTGGACGCTGAAGATGCAGATCATGCCGTT
CGAGGAGGCCAAGACCTACCGGTTCAACCCCTTCGACCTGACCAAGGTCTGGCCGCACGGCGACTACCCGCTGCACGAGG
TCGGCCGGCTGACACTCAACCGCAACATCACCGATTTTCACACGGAGATGGAGCAGGCCGCGTTCGAGCCGAACAACATC
GTCGCGGGCACCGGGCTGTCGCCGGACAAGATGCTGCTCGCTCGCGGGTTCAGCTACGCCGACGCCCACCGGGCCCGCCT
TGGTGTGAACTACAAGCAGATCCCGGTGAACTCCGCGAAGGTGCCCGTCCACAGCTACTCCAAGGACGGCGCGATGCGGG
TGCAGAACGTCACCGACCCGGTGTACGCGCCGAACTCCTACAGCGGCCCGGTGGCCCAGCCGGAGCTGACCGACGACGGC
GGCCACTGGTACTCCGACGGCGAGATGGTTCGCGCCGCTTACACCTCGCGCCCGGAGGACGACGACTGGGGGCAGGCCGG
GACGATGGTCCGCGATGTCCTCGACGACGCCGCGCGGCAGCGGCTGGTCGACAACGTCGTCGGGCACCTGCTCGACGGTG
TCAGCGAACCCGTGCTGGTCCGCGCCTTCGAGTACTGGCGCAATGTCGACAAGGACCTCGGCACCCGGATCGAGGCAGAC
GTACGGGCCAAGCAGGACGAGACCGATCCGAAGGCCGCGCAGCAGGCCAACCCGGCCCGGTCCAGCGCGCAGGCCAAGGC
CTGA

Upstream 100 bases:

>100_bases
ATCGCCGAGGCCGGGATCGCGGTCCGGGACGGGTGCCGCGGCTGTCGACCGGGTGGGCAAGTCCCGCGATGTCAAATCCC
GCGATGTTATGGAGTGAGTC

Downstream 100 bases:

>100_bases
CCGTCCGCCGGCCGTGGCCCGGGGCCCGCCCTCCCAGCCGGGCCCGAACCACGGCCGGCGGCGCCACCTCCGCCACTACC
GCGAGTCCGCCACTACCGCG

Product: catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 507; Mature: 506

Protein sequence:

>507_residues
MTVQKPRPTTTDAGIPVASDEHSLSVGPDGPLLLQDHYLIEQMANFNRERIPERQPHAKGGGAFGTFQVTQDMSAFTRAA
VFQPGTETDVIIRFSTVAGERGSPDTWRDPRGFAVKFYTSEGNLDIVGNNTPVFFIRDPLKFQHFIRSQKRRADNNLRDH
DMQWDFWTLSPESAHQVTWLMGDRGIPRTWRHMNGYSSHTYMWINAAGERFWVKYHFKTDQGIEFFTQDEGDQMASVDTD
YHQRDLFEHIAAGDFPSWTLKMQIMPFEEAKTYRFNPFDLTKVWPHGDYPLHEVGRLTLNRNITDFHTEMEQAAFEPNNI
VAGTGLSPDKMLLARGFSYADAHRARLGVNYKQIPVNSAKVPVHSYSKDGAMRVQNVTDPVYAPNSYSGPVAQPELTDDG
GHWYSDGEMVRAAYTSRPEDDDWGQAGTMVRDVLDDAARQRLVDNVVGHLLDGVSEPVLVRAFEYWRNVDKDLGTRIEAD
VRAKQDETDPKAAQQANPARSSAQAKA

Sequences:

>Translated_507_residues
MTVQKPRPTTTDAGIPVASDEHSLSVGPDGPLLLQDHYLIEQMANFNRERIPERQPHAKGGGAFGTFQVTQDMSAFTRAA
VFQPGTETDVIIRFSTVAGERGSPDTWRDPRGFAVKFYTSEGNLDIVGNNTPVFFIRDPLKFQHFIRSQKRRADNNLRDH
DMQWDFWTLSPESAHQVTWLMGDRGIPRTWRHMNGYSSHTYMWINAAGERFWVKYHFKTDQGIEFFTQDEGDQMASVDTD
YHQRDLFEHIAAGDFPSWTLKMQIMPFEEAKTYRFNPFDLTKVWPHGDYPLHEVGRLTLNRNITDFHTEMEQAAFEPNNI
VAGTGLSPDKMLLARGFSYADAHRARLGVNYKQIPVNSAKVPVHSYSKDGAMRVQNVTDPVYAPNSYSGPVAQPELTDDG
GHWYSDGEMVRAAYTSRPEDDDWGQAGTMVRDVLDDAARQRLVDNVVGHLLDGVSEPVLVRAFEYWRNVDKDLGTRIEAD
VRAKQDETDPKAAQQANPARSSAQAKA
>Mature_506_residues
TVQKPRPTTTDAGIPVASDEHSLSVGPDGPLLLQDHYLIEQMANFNRERIPERQPHAKGGGAFGTFQVTQDMSAFTRAAV
FQPGTETDVIIRFSTVAGERGSPDTWRDPRGFAVKFYTSEGNLDIVGNNTPVFFIRDPLKFQHFIRSQKRRADNNLRDHD
MQWDFWTLSPESAHQVTWLMGDRGIPRTWRHMNGYSSHTYMWINAAGERFWVKYHFKTDQGIEFFTQDEGDQMASVDTDY
HQRDLFEHIAAGDFPSWTLKMQIMPFEEAKTYRFNPFDLTKVWPHGDYPLHEVGRLTLNRNITDFHTEMEQAAFEPNNIV
AGTGLSPDKMLLARGFSYADAHRARLGVNYKQIPVNSAKVPVHSYSKDGAMRVQNVTDPVYAPNSYSGPVAQPELTDDGG
HWYSDGEMVRAAYTSRPEDDDWGQAGTMVRDVLDDAARQRLVDNVVGHLLDGVSEPVLVRAFEYWRNVDKDLGTRIEADV
RAKQDETDPKAAQQANPARSSAQAKA

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=494, Percent_Identity=49.1902834008097, Blast_Score=466, Evalue=1e-131,
Organism=Escherichia coli, GI48994891, Length=386, Percent_Identity=43.5233160621762, Blast_Score=317, Evalue=2e-87,
Organism=Caenorhabditis elegans, GI71998444, Length=487, Percent_Identity=46.8172484599589, Blast_Score=440, Evalue=1e-124,
Organism=Caenorhabditis elegans, GI25151141, Length=485, Percent_Identity=44.3298969072165, Blast_Score=410, Evalue=1e-115,
Organism=Caenorhabditis elegans, GI25147792, Length=487, Percent_Identity=44.1478439425051, Blast_Score=409, Evalue=1e-114,
Organism=Saccharomyces cerevisiae, GI6320462, Length=490, Percent_Identity=44.6938775510204, Blast_Score=392, Evalue=1e-110,
Organism=Saccharomyces cerevisiae, GI6321525, Length=503, Percent_Identity=37.7733598409543, Blast_Score=324, Evalue=2e-89,
Organism=Drosophila melanogaster, GI17981717, Length=480, Percent_Identity=48.75, Blast_Score=456, Evalue=1e-128,
Organism=Drosophila melanogaster, GI19920968, Length=472, Percent_Identity=45.1271186440678, Blast_Score=407, Evalue=1e-114,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 57432; Mature: 57301

Theoretical pI: Translated: 5.81; Mature: 5.81

Prosite motif: PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVQKPRPTTTDAGIPVASDEHSLSVGPDGPLLLQDHYLIEQMANFNRERIPERQPHAKG
CCCCCCCCCCCCCCCCCCCCCCCEEECCCCCEEEEHHHHHHHHHCCCHHHCCCCCCCCCC
GGAFGTFQVTQDMSAFTRAAVFQPGTETDVIIRFSTVAGERGSPDTWRDPRGFAVKFYTS
CCCEEEEEEHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCEEEEEEC
EGNLDIVGNNTPVFFIRDPLKFQHFIRSQKRRADNNLRDHDMQWDFWTLSPESAHQVTWL
CCCEEEEECCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCEEEEE
MGDRGIPRTWRHMNGYSSHTYMWINAAGERFWVKYHFKTDQGIEFFTQDEGDQMASVDTD
ECCCCCCHHHHHCCCCCCCEEEEEEECCCEEEEEEEEECCCCCEEEECCCCCCEECCCCC
YHQRDLFEHIAAGDFPSWTLKMQIMPFEEAKTYRFNPFDLTKVWPHGDYPLHEVGRLTLN
HHHHHHHHHHHCCCCCCEEEEEEEEEHHCCCCEECCCCCCEEECCCCCCCHHHHCEEEEC
RNITDFHTEMEQAAFEPNNIVAGTGLSPDKMLLARGFSYADAHRARLGVNYKQIPVNSAK
CCCHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHCCCCHHHHHHHHHCCCEEECCCCCCC
VPVHSYSKDGAMRVQNVTDPVYAPNSYSGPVAQPELTDDGGHWYSDGEMVRAAYTSRPED
CCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCEEEEECCCCCCC
DDWGQAGTMVRDVLDDAARQRLVDNVVGHLLDGVSEPVLVRAFEYWRNVDKDLGTRIEAD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEHH
VRAKQDETDPKAAQQANPARSSAQAKA
HHCCCCCCCCHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TVQKPRPTTTDAGIPVASDEHSLSVGPDGPLLLQDHYLIEQMANFNRERIPERQPHAKG
CCCCCCCCCCCCCCCCCCCCCCEEECCCCCEEEEHHHHHHHHHCCCHHHCCCCCCCCCC
GGAFGTFQVTQDMSAFTRAAVFQPGTETDVIIRFSTVAGERGSPDTWRDPRGFAVKFYTS
CCCEEEEEEHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCCCCCCCCCEEEEEEC
EGNLDIVGNNTPVFFIRDPLKFQHFIRSQKRRADNNLRDHDMQWDFWTLSPESAHQVTWL
CCCEEEEECCCCEEEEECCHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCCCCCCEEEEE
MGDRGIPRTWRHMNGYSSHTYMWINAAGERFWVKYHFKTDQGIEFFTQDEGDQMASVDTD
ECCCCCCHHHHHCCCCCCCEEEEEEECCCEEEEEEEEECCCCCEEEECCCCCCEECCCCC
YHQRDLFEHIAAGDFPSWTLKMQIMPFEEAKTYRFNPFDLTKVWPHGDYPLHEVGRLTLN
HHHHHHHHHHHCCCCCCEEEEEEEEEHHCCCCEECCCCCCEEECCCCCCCHHHHCEEEEC
RNITDFHTEMEQAAFEPNNIVAGTGLSPDKMLLARGFSYADAHRARLGVNYKQIPVNSAK
CCCHHHHHHHHHHHCCCCCEEEECCCCCHHHHHHCCCCHHHHHHHHHCCCEEECCCCCCC
VPVHSYSKDGAMRVQNVTDPVYAPNSYSGPVAQPELTDDGGHWYSDGEMVRAAYTSRPED
CCCCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCCEEEEECCCCCCC
DDWGQAGTMVRDVLDDAARQRLVDNVVGHLLDGVSEPVLVRAFEYWRNVDKDLGTRIEAD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCEEHH
VRAKQDETDPKAAQQANPARSSAQAKA
HHCCCCCCCCHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1426241; 12454454 [H]