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The map label for this gene is pcm [H]

Identifier: 158318489

GI number: 158318489

Start: 8218955

End: 8220208

Strand: Reverse

Name: pcm [H]

Synonym: Franean1_6757

Alternate gene names: 158318489

Gene position: 8220208-8218955 (Counterclockwise)

Preceding gene: 158318490

Following gene: 158318488

Centisome position: 91.52

GC content: 70.26

Gene sequence:

>1254_bases
ATGAGCGTCGGCACCATGAGTAGCGAGAGTGAGCGCTTCCGTCACGCGATGGTCGACCAGTTCGTTGCCGATCAGGCGGC
GGAAGGCTGCTCGCCGCGCCCGGAAGTGGAGGCGGCGATGCGGGCTGTTCCTCGTGAGCTGTTCACGCCGGGCCTTCCGC
TGGAACAGGCGTATGAGAACGAAGCTGTCCTGAAGAAGATGCGCGGGGACGAAGCGATCAGTTCGGTGTCGGCCCCGTTC
CTGATCGGGCGGATGCTGGGTCAGGCGGCAGACGCGCTCGATGGGCTGGATGGCCGGCACGTGCTGGAGATCGGCAGCGG
TGGCTACAACGCCTCGCTGCTGCGGGAACTCGTCGGCTCGTCAGGATCGGTCACGACGGTCGACATCGACCCCGAGGTGA
CCGACCGGGCGGTTTCCTGCCTGGCAGCGGCCGGCTACGACGACGTCACCGTGGTCTGCGCGGACGCCGAACACCCGATC
GCGCCCGGCCGCCGCTGGGATTTGATCATTGTCACGGTCGGGGCGTGGGACATCCCGCCGGCGTGGCGTGATCAGCTCAC
CGACGGGGGCGTGCTGGTGGTGCCGCTGCGTACGTTCGGGATGACTCGGTCGTGGGCGTTGCGGCGCCGCGAGGGCCGCC
TGGTCAGCGTGAGCCAGCGGTTGTGCGGGTTCGTCTCGATGCAGGGCGCCGGCGCCAGCGAGGTGCGCTACGCCGACATC
GCGGACGGTGTGCACCTGCGGCTGGATGAGGGTCAACACGTCGATTCGGCCGCGGTCGCTGATCTCCTCACGACGCCACG
CGAGCAGGTGTGGGCCGAGGTGAGCCTGCCGCCCCGCACCGATCTGTCCGACCTCGACCTGTGGCTGGCGACTCGACCGC
AGGTCGAGGCGGAGCAGTTCGTCGTCCTCGCCGCGCAGGAGGAAGCGGTCACGGCCGGCATCGTCACGCCCTCGTGGCGG
TTCGCCGTCCCGGCCACGCTGGCGGCCGGCACGCTGGCCTACCGGTCGGCGCTGCGCTGGACCGACCGGCGGTTCGATCT
CGGCGCATGTGCCCACGGGACTGGGGCCGCCGCGGCGGCCGGGCGGATGGTCGAGCACATGCGTGCGTGGGTGGATGCGG
GCTGCCCGCCTCCGGTGCTGCACATCCTGCCCGCGCACACCCCCGATGGCGACGTGCCGGAGGGGGCGGTCCTGGACAAG
CGGCACAGCCGCCTCGTCCTGACCTTCACCACAGAGAAGAAGGGAACCACCTGA

Upstream 100 bases:

>100_bases
GAGTACGAGGCAGAACCGGTAGCTGATTACCGGCCTGTTGGAATGCCGGGGGCCGCCCGGACCGCGGCGGCTCGCACGCA
TCGAGAGAGGAATCTCAAGG

Downstream 100 bases:

>100_bases
TGGACAACGAGCACGACCTGGACCTGAACCTGGTCGACGCCGGGCCCGTCGCGAGTCCGCACGCCACCGGCACCGACGAC
AACTGCGGCTCGGGCAACAC

Product: protein-L-isoaspartate(D-aspartate) O-methyltransferase

Products: NA

Alternate protein names: L-isoaspartyl protein carboxyl methyltransferase; Protein L-isoaspartyl methyltransferase; Protein-beta-aspartate methyltransferase; PIMT [H]

Number of amino acids: Translated: 417; Mature: 416

Protein sequence:

>417_residues
MSVGTMSSESERFRHAMVDQFVADQAAEGCSPRPEVEAAMRAVPRELFTPGLPLEQAYENEAVLKKMRGDEAISSVSAPF
LIGRMLGQAADALDGLDGRHVLEIGSGGYNASLLRELVGSSGSVTTVDIDPEVTDRAVSCLAAAGYDDVTVVCADAEHPI
APGRRWDLIIVTVGAWDIPPAWRDQLTDGGVLVVPLRTFGMTRSWALRRREGRLVSVSQRLCGFVSMQGAGASEVRYADI
ADGVHLRLDEGQHVDSAAVADLLTTPREQVWAEVSLPPRTDLSDLDLWLATRPQVEAEQFVVLAAQEEAVTAGIVTPSWR
FAVPATLAAGTLAYRSALRWTDRRFDLGACAHGTGAAAAAGRMVEHMRAWVDAGCPPPVLHILPAHTPDGDVPEGAVLDK
RHSRLVLTFTTEKKGTT

Sequences:

>Translated_417_residues
MSVGTMSSESERFRHAMVDQFVADQAAEGCSPRPEVEAAMRAVPRELFTPGLPLEQAYENEAVLKKMRGDEAISSVSAPF
LIGRMLGQAADALDGLDGRHVLEIGSGGYNASLLRELVGSSGSVTTVDIDPEVTDRAVSCLAAAGYDDVTVVCADAEHPI
APGRRWDLIIVTVGAWDIPPAWRDQLTDGGVLVVPLRTFGMTRSWALRRREGRLVSVSQRLCGFVSMQGAGASEVRYADI
ADGVHLRLDEGQHVDSAAVADLLTTPREQVWAEVSLPPRTDLSDLDLWLATRPQVEAEQFVVLAAQEEAVTAGIVTPSWR
FAVPATLAAGTLAYRSALRWTDRRFDLGACAHGTGAAAAAGRMVEHMRAWVDAGCPPPVLHILPAHTPDGDVPEGAVLDK
RHSRLVLTFTTEKKGTT
>Mature_416_residues
SVGTMSSESERFRHAMVDQFVADQAAEGCSPRPEVEAAMRAVPRELFTPGLPLEQAYENEAVLKKMRGDEAISSVSAPFL
IGRMLGQAADALDGLDGRHVLEIGSGGYNASLLRELVGSSGSVTTVDIDPEVTDRAVSCLAAAGYDDVTVVCADAEHPIA
PGRRWDLIIVTVGAWDIPPAWRDQLTDGGVLVVPLRTFGMTRSWALRRREGRLVSVSQRLCGFVSMQGAGASEVRYADIA
DGVHLRLDEGQHVDSAAVADLLTTPREQVWAEVSLPPRTDLSDLDLWLATRPQVEAEQFVVLAAQEEAVTAGIVTPSWRF
AVPATLAAGTLAYRSALRWTDRRFDLGACAHGTGAAAAAGRMVEHMRAWVDAGCPPPVLHILPAHTPDGDVPEGAVLDKR
HSRLVLTFTTEKKGTT

Specific function: Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins [H]

COG id: COG2518

COG function: function code O; Protein-L-isoaspartate carboxylmethyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily. L- isoaspartyl/D-aspartyl protein methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000682 [H]

Pfam domain/function: PF01135 PCMT [H]

EC number: =2.1.1.77 [H]

Molecular weight: Translated: 44746; Mature: 44615

Theoretical pI: Translated: 4.84; Mature: 4.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSVGTMSSESERFRHAMVDQFVADQAAEGCSPRPEVEAAMRAVPRELFTPGLPLEQAYEN
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHCH
EAVLKKMRGDEAISSVSAPFLIGRMLGQAADALDGLDGRHVLEIGSGGYNASLLRELVGS
HHHHHHHCCHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHCC
SGSVTTVDIDPEVTDRAVSCLAAAGYDDVTVVCADAEHPIAPGRRWDLIIVTVGAWDIPP
CCCEEEEECCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEEEEEEEECCCCCCH
AWRDQLTDGGVLVVPLRTFGMTRSWALRRREGRLVSVSQRLCGFVSMQGAGASEVRYADI
HHHHHCCCCCEEEEEHHHHCCCHHHHHHHHCCCEEEHHHHHHHHHEECCCCCCCEEEEEC
ADGVHLRLDEGQHVDSAAVADLLTTPREQVWAEVSLPPRTDLSDLDLWLATRPQVEAEQF
CCCEEEEECCCCCCCHHHHHHHHHCCHHHHEEEECCCCCCCCCCCEEEEECCCCCCCCEE
VVLAAQEEAVTAGIVTPSWRFAVPATLAAGTLAYRSALRWTDRRFDLGACAHGTGAAAAA
EEEEECCCCEEEEECCCCCCEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHH
GRMVEHMRAWVDAGCPPPVLHILPAHTPDGDVPEGAVLDKRHSRLVLTFTTEKKGTT
HHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCEECCCCCEEEEEEECCCCCCC
>Mature Secondary Structure 
SVGTMSSESERFRHAMVDQFVADQAAEGCSPRPEVEAAMRAVPRELFTPGLPLEQAYEN
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHCH
EAVLKKMRGDEAISSVSAPFLIGRMLGQAADALDGLDGRHVLEIGSGGYNASLLRELVGS
HHHHHHHCCHHHHHHHCHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCCHHHHHHHHCC
SGSVTTVDIDPEVTDRAVSCLAAAGYDDVTVVCADAEHPIAPGRRWDLIIVTVGAWDIPP
CCCEEEEECCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCCEEEEEEEECCCCCCH
AWRDQLTDGGVLVVPLRTFGMTRSWALRRREGRLVSVSQRLCGFVSMQGAGASEVRYADI
HHHHHCCCCCEEEEEHHHHCCCHHHHHHHHCCCEEEHHHHHHHHHEECCCCCCCEEEEEC
ADGVHLRLDEGQHVDSAAVADLLTTPREQVWAEVSLPPRTDLSDLDLWLATRPQVEAEQF
CCCEEEEECCCCCCCHHHHHHHHHCCHHHHEEEECCCCCCCCCCCEEEEECCCCCCCCEE
VVLAAQEEAVTAGIVTPSWRFAVPATLAAGTLAYRSALRWTDRRFDLGACAHGTGAAAAA
EEEEECCCCEEEEECCCCCCEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHH
GRMVEHMRAWVDAGCPPPVLHILPAHTPDGDVPEGAVLDKRHSRLVLTFTTEKKGTT
HHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCCCEECCCCCEEEEEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA