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The map label for this gene is algD [H]

Identifier: 158318412

GI number: 158318412

Start: 8111878

End: 8112963

Strand: Reverse

Name: algD [H]

Synonym: Franean1_6677

Alternate gene names: 158318412

Gene position: 8112963-8111878 (Counterclockwise)

Preceding gene: 158318413

Following gene: 158318411

Centisome position: 90.32

GC content: 70.26

Gene sequence:

>1086_bases
ATGCGAATCTTTGTCGTCGGATCCGGAGTCGTGGGAACAGCCACCGGGAGGGGGCTGCTCGACGCCGGGCACCGGGTCAC
GTTCATCGACGTCTCACCGGAGCGAGTCGCATTCCTGAACGAGATCGGCCTGGACGCGCGGCCCGAGATCGACCTGAGAT
CGGAGGGCGACTCCCTCGTCTTTCTCACCCTGCCGACACCGAACGCCGGCAGCCGCTACGACCTCGCGGCGTTCGTGGCC
GGTACCCGCGGCCTCGGCCGCGCCCTGTGCGAGACGTCCGCCGTGCACACCGTGGTTGTTCGCAGCACCGTCGATCCGGG
CACGACCGAGGGGCTGGTGGGCCCGCTGCTGGAGCAGGAGTCCGGGCTGCGTCAGGGCAGCGGGTTCCTGCTGGCCAGCA
ATCCGGAGTTCCTGCGCGCCTCGTCGGCCGCCGAGGACTTCCGCTGGCCGTGGATGACCGTCATCGGGGCTCGTAACCGG
CGGGTCCAGGAGCGCCTCGCGGAGCTTTTCGCGCCTTTCGGGGGGACCATGAGGATCTTCGGTGACCCGACGACCGCCGA
GTTCGTCAAGTGTGCGCACAACATCTTCAACGCCACGAAGATCTCGTTCTGGAACGAGATGCACGTCGTCGCAGAGCGTC
TTCAGATCGACCTCGGGGCGGTGTCCGAGACGGTCTCGCGGTCGGCCGAGGCGTCCTTCAACCCCGCCTACGGGACCAGG
GGCGGCGCGCCGTACGGGGGTGTCTGCCTGCCGAAGGACACCATGGCCTTCCTCGGGTTCGCCGCTGGTGTCGGCGTGGA
CATGCCGATTCTGCGGTCGGTCATCGAGATGAACAGCCGCTTCGTCGACCGCGTGGCCGCCGACGGCGCCGTGAGCGGCG
AGCGGGTCGCCGAGCTGGTTGGCGGGCGAGCCGCTGACTCGCTCGGGGACAGGTCCGGCAACGGGTTCGGTGACGGGTTC
GGTGGCGGCGCCACCGAACCGGGGGCGGGGCTGGCCTCCGCCCGCGCGCTCTGGTCGCCCGACCGGCTTCCACGGCAGCC
GCGGGACTCCCGTGGCGTCGAGGCGACGGAAGGCGCGCCCCGATGA

Upstream 100 bases:

>100_bases
CCGCCGCCCTACGCGCGGATTCTCGGACGTCATCGTCCGCGCCCGCTCGACGCCGCCCGGGCCGACCATGCCCTGAGCGC
GCCCCAAGGAGCTGAAGAAG

Downstream 100 bases:

>100_bases
GCACCCTGCTGCCCTGGCTGTTGCTTGTGGCCTTCCTCCGGCCAATGATCGAGATCTTCATTCTTGCCGCGGGTGAGTGG
TGGTTCCACACGACCTTCCG

Product: UDP-glucose 6-dehydrogenase

Products: NA

Alternate protein names: GMD [H]

Number of amino acids: Translated: 361; Mature: 361

Protein sequence:

>361_residues
MRIFVVGSGVVGTATGRGLLDAGHRVTFIDVSPERVAFLNEIGLDARPEIDLRSEGDSLVFLTLPTPNAGSRYDLAAFVA
GTRGLGRALCETSAVHTVVVRSTVDPGTTEGLVGPLLEQESGLRQGSGFLLASNPEFLRASSAAEDFRWPWMTVIGARNR
RVQERLAELFAPFGGTMRIFGDPTTAEFVKCAHNIFNATKISFWNEMHVVAERLQIDLGAVSETVSRSAEASFNPAYGTR
GGAPYGGVCLPKDTMAFLGFAAGVGVDMPILRSVIEMNSRFVDRVAADGAVSGERVAELVGGRAADSLGDRSGNGFGDGF
GGGATEPGAGLASARALWSPDRLPRQPRDSRGVEATEGAPR

Sequences:

>Translated_361_residues
MRIFVVGSGVVGTATGRGLLDAGHRVTFIDVSPERVAFLNEIGLDARPEIDLRSEGDSLVFLTLPTPNAGSRYDLAAFVA
GTRGLGRALCETSAVHTVVVRSTVDPGTTEGLVGPLLEQESGLRQGSGFLLASNPEFLRASSAAEDFRWPWMTVIGARNR
RVQERLAELFAPFGGTMRIFGDPTTAEFVKCAHNIFNATKISFWNEMHVVAERLQIDLGAVSETVSRSAEASFNPAYGTR
GGAPYGGVCLPKDTMAFLGFAAGVGVDMPILRSVIEMNSRFVDRVAADGAVSGERVAELVGGRAADSLGDRSGNGFGDGF
GGGATEPGAGLASARALWSPDRLPRQPRDSRGVEATEGAPR
>Mature_361_residues
MRIFVVGSGVVGTATGRGLLDAGHRVTFIDVSPERVAFLNEIGLDARPEIDLRSEGDSLVFLTLPTPNAGSRYDLAAFVA
GTRGLGRALCETSAVHTVVVRSTVDPGTTEGLVGPLLEQESGLRQGSGFLLASNPEFLRASSAAEDFRWPWMTVIGARNR
RVQERLAELFAPFGGTMRIFGDPTTAEFVKCAHNIFNATKISFWNEMHVVAERLQIDLGAVSETVSRSAEASFNPAYGTR
GGAPYGGVCLPKDTMAFLGFAAGVGVDMPILRSVIEMNSRFVDRVAADGAVSGERVAELVGGRAADSLGDRSGNGFGDGF
GGGATEPGAGLASARALWSPDRLPRQPRDSRGVEATEGAPR

Specific function: Catalyzes the oxidation of guanosine diphospho-D-mannose (GDP-D-mannose) to GDP-D-mannuronic acid, a precursor for alginate polymerization. The alginate layer causes a mucoid phenotype and provides a protective barrier against host immune defenses and ant

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1788340, Length=281, Percent_Identity=28.8256227758007, Blast_Score=85, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.132 [H]

Molecular weight: Translated: 38073; Mature: 38073

Theoretical pI: Translated: 5.27; Mature: 5.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIFVVGSGVVGTATGRGLLDAGHRVTFIDVSPERVAFLNEIGLDARPEIDLRSEGDSLV
CEEEEEECCEEECCCCCCHHCCCCEEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCEE
FLTLPTPNAGSRYDLAAFVAGTRGLGRALCETSAVHTVVVRSTVDPGTTEGLVGPLLEQE
EEEECCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHEEEEEEECCCCCCCCHHHHHHHHHH
SGLRQGSGFLLASNPEFLRASSAAEDFRWPWMTVIGARNRRVQERLAELFAPFGGTMRIF
CCCCCCCCEEEECCCHHHHHCCCHHHCCCCCEEECCCCCHHHHHHHHHHHCCCCCEEEEE
GDPTTAEFVKCAHNIFNATKISFWNEMHVVAERLQIDLGAVSETVSRSAEASFNPAYGTR
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
GGAPYGGVCLPKDTMAFLGFAAGVGVDMPILRSVIEMNSRFVDRVAADGAVSGERVAELV
CCCCCCCEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
GGRAADSLGDRSGNGFGDGFGGGATEPGAGLASARALWSPDRLPRQPRDSRGVEATEGAP
CCCHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
R
C
>Mature Secondary Structure
MRIFVVGSGVVGTATGRGLLDAGHRVTFIDVSPERVAFLNEIGLDARPEIDLRSEGDSLV
CEEEEEECCEEECCCCCCHHCCCCEEEEEECCHHHHHHHHHHCCCCCCCCCCCCCCCCEE
FLTLPTPNAGSRYDLAAFVAGTRGLGRALCETSAVHTVVVRSTVDPGTTEGLVGPLLEQE
EEEECCCCCCCCCCHHHHHHCCCHHHHHHHHHHHHEEEEEEECCCCCCCCHHHHHHHHHH
SGLRQGSGFLLASNPEFLRASSAAEDFRWPWMTVIGARNRRVQERLAELFAPFGGTMRIF
CCCCCCCCEEEECCCHHHHHCCCHHHCCCCCEEECCCCCHHHHHHHHHHHCCCCCEEEEE
GDPTTAEFVKCAHNIFNATKISFWNEMHVVAERLQIDLGAVSETVSRSAEASFNPAYGTR
CCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCC
GGAPYGGVCLPKDTMAFLGFAAGVGVDMPILRSVIEMNSRFVDRVAADGAVSGERVAELV
CCCCCCCEECCHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
GGRAADSLGDRSGNGFGDGFGGGATEPGAGLASARALWSPDRLPRQPRDSRGVEATEGAP
CCCHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCCCCCCCCC
R
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3108855; 10984043; 2470755; 1370473; 8294014; 12135385; 12705829 [H]