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The map label for this gene is dnaX [H]

Identifier: 158318299

GI number: 158318299

Start: 7985102

End: 7987669

Strand: Direct

Name: dnaX [H]

Synonym: Franean1_6564

Alternate gene names: 158318299

Gene position: 7985102-7987669 (Clockwise)

Preceding gene: 158318298

Following gene: 158318300

Centisome position: 88.9

GC content: 76.09

Gene sequence:

>2568_bases
GTGAGCACAGCGCTGTACAACAGGTACCGCCCCGCGACGTTCGCCCAGGTTGTCGGCCAGGAGCACGTCACGGAGGCACT
GGGGCACGCGCTGCGCTCCGGGCGGCTGCACCACGCCTACCTGTTCAGCGGCCCGCGAGGCTGCGGGAAGACCTCGTCCG
CCCGGATCCTGGCGGCCTCCCTGAACTGCGAGAAGGGGCCGACCCCGGAGCCGTGCGGGGTGTGCGATCAGTGCGTCTCC
ATCCGCACCGGCTCCTCGATGGACGTCACCGAGATCGACGCCGCTTCGCACGGCCTCGTCGACGATGCCCGTGACCTGCG
GGAACGCGCCTTCTTCGCGCCGGCGTCCGCCCGGTTCAAGGTGTTCGTGGTCGACGAGGCGCACATGGTCACGGCGGCGG
CGTTCAACGCGCTGCTGAAGGTCGTCGAGGAGCCGCCGTCCTACCTGAAGTTCGTCTTCGCCACCACCGAGCCGGACAAG
GTCATCGCGACGATCCGGTCCCGGACGCACCACTACGCCTTCCGTCTGGTGCCTCCTGGTGTGCTCCGCAAGCACCTGGA
GTCGATCTGCGCGCAGGAAGGCGTGGTCGTTGAGCCGTCGGTGCTCCCGCTGGTGGTGCGGGCGGGCGCGGGCTCCGTCC
GGGATTCGCTCTCCGTTCTCGACCAGCTTCTGGCCGGCGCCGGCGACGGCGGGCTCAGCTACGAGCGCGCGGTGGCGCTG
TTGGGCATGACGGACGGCATCCTGCTCGACGAGACTGTGGACGCCCTCGCCGAACGCGACGGCGCCGCGCTGTTCACCGT
GGTCGACAGTGTGGTCTCCTCCGGTCACGATCCACGCCGGTTCGCGACCGACCTGCTCGATCGGCTCCGTGATCTCATCG
TGGTCGCCGCGGTGCCGGACGCGGTGGAACGCGGCCTGCTCGAGGCGTTCTCCACCGACCAGGTGGACCGGATGCGCGCC
CAGGCCGGCCGGATCGGGCCGGTCGAGCTCTCCCGGACGGCCGACGTCCTGCATGCGGGTCTGGTCGAGATGCGCGGGAC
GGCGAGCCCACGGCTGTTGCTGGAGCTGATCCTCGCCCGCGCCCTCCTCCCGGGCGCCGCCGGGGATCCGGCCGCGCTCG
CCGTCCGGCTCGAGCGGCTGGAGCGCCGAGCGGTGGTCGGCGGCGGAGCCGGTGCCGGCACGACCCCGACTGGCGGCGCC
GAGGTCGGTGGTGCGACGCACGCCGACGCGAGGTTCGGTGGCGCCCGGCCCGCTGACGGGGGGCCCGGGTTCGGTGGCGC
CGCTGACAGTGCTCACGGGCAGGCCGCGGCACACGCCCCGGCGCCGGCGGCGCATACCCAGACGGCCCGGCCGGCTTCGC
CCGCACGGCCCGCGATGCCGGCTGCCGCGGCCCCCGGCGGGGGCGGGCTCGACGCGGCGGCCCTGAACGCCCGCTGGGAC
GAGGTGCTCGCGCTCGCCGTCCAGCGCAGCCGGCGCACCCACGCGATCCTCAAGGACTACGCCTCGGTCGCCGAGGTCCG
CGGGGACGAGGTCGTCCTCGCCTTCTCCGCACCGGCCATGGCGAAGATGTTCGGCCAGGGGAACAACGTCGAGATCCTCG
CAACCCTGCTGGCTGAGAAGTTCGGTGGGACATGGCGGGTCACGATCGGCGGTGGCCCCGGGTCCTCGGGAGGCCGTCCC
CAGGCACCGCGCGGGGGGCCCGGCAACGGCCGGCCCGACAACGGCAACGGCGGCGGGCCAGGCGGCTACAGCGGTCCCGG
TGGCCCAGGCGGCCCGGGTGGTCCGGGTGGCGGCCAGCGGGGGCCGACCGAGCAGGCCGGCGGCGGCCGGCCCGCGGAGG
CGGTGGCCCCGCAGCGGCCCAATGGTTACGGCGGTCCCGCCGGGCAGGCGAGCCCGGGCGGCCCGTCCTCGCCGGGGGCG
GTCGACCCGAGCGGCGGGCATCCGGGCGGGTACTCCGACGCCCACGGCGGCCCGGCGGTTCCGGTGAACGCGGGCGCTCC
CGGCGGCTGGTCCGCGGCGGGAGCCGGCGCGAGCCGTGGCTCGGGAGCACCAGGGGCCACCCTCCCGGCTCCCTCCGGTG
TCTCCGCCGCGCCGGCGTCCATGGCGCACGCCGGGTCCTCCGGCCCGGCCGCGCAGGACGGGCTCCCCCGCCCGCCGGCC
GGCCTCCACTCGGCGACGGCCACAGCCAGCCTGGGAAACGCGAGCGTGAGCGGCGCGGCCGCGGGGTCCGGTGTGGGCTC
CACCGCCGTCGCCGTCCCCCGCCTGGGCACCGCGGAGGCCGGGCTTGCCGCGGCGCGGGCGGCGGTGAGCGCAAGAACCG
GCCTCAACGGCTCCACTCGGACGCCGACCGGTCCCGGAGGGGGACCGAGAGCGGCGGGCGCGGCACGGCCGGGGGGTGCC
TCCGTGGCGGCGGCGTCGATGTCCGCCACGGACACCGCGCCGGACGAGGTCTCGCTCGACGACGAGGACGCGCCGACCCA
GCTGGGCGGGGCCCGGGGCGGCGAGGACGCGGCCGTGGCCCTGCTCCGCACGAGTCTGGGCGCGACGGTGATCGAGCAGT
CCGGCTGA

Upstream 100 bases:

>100_bases
TCCCCCAGGGCCGGAAGGCAGCAAGGGTAAGCGGGCTCTGGCGGGTGTGCGGGGGGTCCTCCTCGTTCGGACGATCATCT
CGAGCATCCGGAGCAGGCGA

Downstream 100 bases:

>100_bases
CGGACGAGCGCCGGTGGGTGACCGAGCGGGCTGGGTGGGCGGTTCGGGTGGGCAGTACGGGTGGCTGACACCGGTTCGGC
GCCCGGCGGCACGTAGGCTC

Product: DNA polymerase III subunits gamma and tau

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 855; Mature: 854

Protein sequence:

>855_residues
MSTALYNRYRPATFAQVVGQEHVTEALGHALRSGRLHHAYLFSGPRGCGKTSSARILAASLNCEKGPTPEPCGVCDQCVS
IRTGSSMDVTEIDAASHGLVDDARDLRERAFFAPASARFKVFVVDEAHMVTAAAFNALLKVVEEPPSYLKFVFATTEPDK
VIATIRSRTHHYAFRLVPPGVLRKHLESICAQEGVVVEPSVLPLVVRAGAGSVRDSLSVLDQLLAGAGDGGLSYERAVAL
LGMTDGILLDETVDALAERDGAALFTVVDSVVSSGHDPRRFATDLLDRLRDLIVVAAVPDAVERGLLEAFSTDQVDRMRA
QAGRIGPVELSRTADVLHAGLVEMRGTASPRLLLELILARALLPGAAGDPAALAVRLERLERRAVVGGGAGAGTTPTGGA
EVGGATHADARFGGARPADGGPGFGGAADSAHGQAAAHAPAPAAHTQTARPASPARPAMPAAAAPGGGGLDAAALNARWD
EVLALAVQRSRRTHAILKDYASVAEVRGDEVVLAFSAPAMAKMFGQGNNVEILATLLAEKFGGTWRVTIGGGPGSSGGRP
QAPRGGPGNGRPDNGNGGGPGGYSGPGGPGGPGGPGGGQRGPTEQAGGGRPAEAVAPQRPNGYGGPAGQASPGGPSSPGA
VDPSGGHPGGYSDAHGGPAVPVNAGAPGGWSAAGAGASRGSGAPGATLPAPSGVSAAPASMAHAGSSGPAAQDGLPRPPA
GLHSATATASLGNASVSGAAAGSGVGSTAVAVPRLGTAEAGLAAARAAVSARTGLNGSTRTPTGPGGGPRAAGAARPGGA
SVAAASMSATDTAPDEVSLDDEDAPTQLGGARGGEDAAVALLRTSLGATVIEQSG

Sequences:

>Translated_855_residues
MSTALYNRYRPATFAQVVGQEHVTEALGHALRSGRLHHAYLFSGPRGCGKTSSARILAASLNCEKGPTPEPCGVCDQCVS
IRTGSSMDVTEIDAASHGLVDDARDLRERAFFAPASARFKVFVVDEAHMVTAAAFNALLKVVEEPPSYLKFVFATTEPDK
VIATIRSRTHHYAFRLVPPGVLRKHLESICAQEGVVVEPSVLPLVVRAGAGSVRDSLSVLDQLLAGAGDGGLSYERAVAL
LGMTDGILLDETVDALAERDGAALFTVVDSVVSSGHDPRRFATDLLDRLRDLIVVAAVPDAVERGLLEAFSTDQVDRMRA
QAGRIGPVELSRTADVLHAGLVEMRGTASPRLLLELILARALLPGAAGDPAALAVRLERLERRAVVGGGAGAGTTPTGGA
EVGGATHADARFGGARPADGGPGFGGAADSAHGQAAAHAPAPAAHTQTARPASPARPAMPAAAAPGGGGLDAAALNARWD
EVLALAVQRSRRTHAILKDYASVAEVRGDEVVLAFSAPAMAKMFGQGNNVEILATLLAEKFGGTWRVTIGGGPGSSGGRP
QAPRGGPGNGRPDNGNGGGPGGYSGPGGPGGPGGPGGGQRGPTEQAGGGRPAEAVAPQRPNGYGGPAGQASPGGPSSPGA
VDPSGGHPGGYSDAHGGPAVPVNAGAPGGWSAAGAGASRGSGAPGATLPAPSGVSAAPASMAHAGSSGPAAQDGLPRPPA
GLHSATATASLGNASVSGAAAGSGVGSTAVAVPRLGTAEAGLAAARAAVSARTGLNGSTRTPTGPGGGPRAAGAARPGGA
SVAAASMSATDTAPDEVSLDDEDAPTQLGGARGGEDAAVALLRTSLGATVIEQSG
>Mature_854_residues
STALYNRYRPATFAQVVGQEHVTEALGHALRSGRLHHAYLFSGPRGCGKTSSARILAASLNCEKGPTPEPCGVCDQCVSI
RTGSSMDVTEIDAASHGLVDDARDLRERAFFAPASARFKVFVVDEAHMVTAAAFNALLKVVEEPPSYLKFVFATTEPDKV
IATIRSRTHHYAFRLVPPGVLRKHLESICAQEGVVVEPSVLPLVVRAGAGSVRDSLSVLDQLLAGAGDGGLSYERAVALL
GMTDGILLDETVDALAERDGAALFTVVDSVVSSGHDPRRFATDLLDRLRDLIVVAAVPDAVERGLLEAFSTDQVDRMRAQ
AGRIGPVELSRTADVLHAGLVEMRGTASPRLLLELILARALLPGAAGDPAALAVRLERLERRAVVGGGAGAGTTPTGGAE
VGGATHADARFGGARPADGGPGFGGAADSAHGQAAAHAPAPAAHTQTARPASPARPAMPAAAAPGGGGLDAAALNARWDE
VLALAVQRSRRTHAILKDYASVAEVRGDEVVLAFSAPAMAKMFGQGNNVEILATLLAEKFGGTWRVTIGGGPGSSGGRPQ
APRGGPGNGRPDNGNGGGPGGYSGPGGPGGPGGPGGGQRGPTEQAGGGRPAEAVAPQRPNGYGGPAGQASPGGPSSPGAV
DPSGGHPGGYSDAHGGPAVPVNAGAPGGWSAAGAGASRGSGAPGATLPAPSGVSAAPASMAHAGSSGPAAQDGLPRPPAG
LHSATATASLGNASVSGAAAGSGVGSTAVAVPRLGTAEAGLAAARAAVSARTGLNGSTRTPTGPGGGPRAAGAARPGGAS
VAAASMSATDTAPDEVSLDDEDAPTQLGGARGGEDAAVALLRTSLGATVIEQSG

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786676, Length=361, Percent_Identity=41.2742382271468, Blast_Score=262, Evalue=5e-71,
Organism=Saccharomyces cerevisiae, GI6324039, Length=218, Percent_Identity=27.0642201834862, Blast_Score=68, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 84406; Mature: 84275

Theoretical pI: Translated: 6.77; Mature: 6.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTALYNRYRPATFAQVVGQEHVTEALGHALRSGRLHHAYLFSGPRGCGKTSSARILAAS
CCCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCEEEEEE
LNCEKGPTPEPCGVCDQCVSIRTGSSMDVTEIDAASHGLVDDARDLRERAFFAPASARFK
CCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHCCCCCCCHHHHHHHHHHHCCCCCCCCEE
VFVVDEAHMVTAAAFNALLKVVEEPPSYLKFVFATTEPDKVIATIRSRTHHYAFRLVPPG
EEEECCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCEEEEEECCHH
VLRKHLESICAQEGVVVEPSVLPLVVRAGAGSVRDSLSVLDQLLAGAGDGGLSYERAVAL
HHHHHHHHHHHCCCEEECCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
LGMTDGILLDETVDALAERDGAALFTVVDSVVSSGHDPRRFATDLLDRLRDLIVVAAVPD
HCCCCCEEHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEEECCH
AVERGLLEAFSTDQVDRMRAQAGRIGPVELSRTADVLHAGLVEMRGTASPRLLLELILAR
HHHHHHHHHHCCHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
ALLPGAAGDPAALAVRLERLERRAVVGGGAGAGTTPTGGAEVGGATHADARFGGARPADG
HHCCCCCCCHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GPGFGGAADSAHGQAAAHAPAPAAHTQTARPASPARPAMPAAAAPGGGGLDAAALNARWD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
EVLALAVQRSRRTHAILKDYASVAEVRGDEVVLAFSAPAMAKMFGQGNNVEILATLLAEK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHCCCCCHHHHHHHHHHH
FGGTWRVTIGGGPGSSGGRPQAPRGGPGNGRPDNGNGGGPGGYSGPGGPGGPGGPGGGQR
HCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GPTEQAGGGRPAEAVAPQRPNGYGGPAGQASPGGPSSPGAVDPSGGHPGGYSDAHGGPAV
CCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PVNAGAPGGWSAAGAGASRGSGAPGATLPAPSGVSAAPASMAHAGSSGPAAQDGLPRPPA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCC
GLHSATATASLGNASVSGAAAGSGVGSTAVAVPRLGTAEAGLAAARAAVSARTGLNGSTR
CCCHHHHHHCCCCCCCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHCCCCCCCC
TPTGPGGGPRAAGAARPGGASVAAASMSATDTAPDEVSLDDEDAPTQLGGARGGEDAAVA
CCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCHHHCCCCCCHHHHHH
LLRTSLGATVIEQSG
HHHHHHCCHHHCCCC
>Mature Secondary Structure 
STALYNRYRPATFAQVVGQEHVTEALGHALRSGRLHHAYLFSGPRGCGKTSSARILAAS
CCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCEEEEEE
LNCEKGPTPEPCGVCDQCVSIRTGSSMDVTEIDAASHGLVDDARDLRERAFFAPASARFK
CCCCCCCCCCCCCHHHHHHHHCCCCCCCCHHHCCCCCCCHHHHHHHHHHHCCCCCCCCEE
VFVVDEAHMVTAAAFNALLKVVEEPPSYLKFVFATTEPDKVIATIRSRTHHYAFRLVPPG
EEEECCCHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHCCCEEEEEECCHH
VLRKHLESICAQEGVVVEPSVLPLVVRAGAGSVRDSLSVLDQLLAGAGDGGLSYERAVAL
HHHHHHHHHHHCCCEEECCCCEEEEEECCCCHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
LGMTDGILLDETVDALAERDGAALFTVVDSVVSSGHDPRRFATDLLDRLRDLIVVAAVPD
HCCCCCEEHHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHEEEEECCH
AVERGLLEAFSTDQVDRMRAQAGRIGPVELSRTADVLHAGLVEMRGTASPRLLLELILAR
HHHHHHHHHHCCHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
ALLPGAAGDPAALAVRLERLERRAVVGGGAGAGTTPTGGAEVGGATHADARFGGARPADG
HHCCCCCCCHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GPGFGGAADSAHGQAAAHAPAPAAHTQTARPASPARPAMPAAAAPGGGGLDAAALNARWD
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
EVLALAVQRSRRTHAILKDYASVAEVRGDEVVLAFSAPAMAKMFGQGNNVEILATLLAEK
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCHHHHHHHCCCCCHHHHHHHHHHH
FGGTWRVTIGGGPGSSGGRPQAPRGGPGNGRPDNGNGGGPGGYSGPGGPGGPGGPGGGQR
HCCEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
GPTEQAGGGRPAEAVAPQRPNGYGGPAGQASPGGPSSPGAVDPSGGHPGGYSDAHGGPAV
CCCCCCCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
PVNAGAPGGWSAAGAGASRGSGAPGATLPAPSGVSAAPASMAHAGSSGPAAQDGLPRPPA
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCC
GLHSATATASLGNASVSGAAAGSGVGSTAVAVPRLGTAEAGLAAARAAVSARTGLNGSTR
CCCHHHHHHCCCCCCCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHHHHCCCCCCCC
TPTGPGGGPRAAGAARPGGASVAAASMSATDTAPDEVSLDDEDAPTQLGGARGGEDAAVA
CCCCCCCCCCCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCCCCHHHCCCCCCHHHHHH
LLRTSLGATVIEQSG
HHHHHHCCHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]