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The map label for this gene is aphA [H]

Identifier: 158318257

GI number: 158318257

Start: 7929300

End: 7930970

Strand: Reverse

Name: aphA [H]

Synonym: Franean1_6522

Alternate gene names: 158318257

Gene position: 7930970-7929300 (Counterclockwise)

Preceding gene: 158318258

Following gene: 158318256

Centisome position: 88.3

GC content: 71.63

Gene sequence:

>1671_bases
ATGCGCGGCTGGCGGCTGCGCCGGCGGCTCGCCGCGGTGTACATCGCGTTGTCCATGGTGCTGCTGCTGGCCGCCGGGAT
CGTCGCCTGGTCGCTGGTCCGGCTCGACGACGCCATCCATGTGCGCAGCGACGTCCTGGCGCCCGCGCAGACAGTCACGG
TCCGGTTGACGTCCAGCCTGGTCGACCAGGAGACCGGCATGCGCGGGTATCTCCTGCAGGGCGACCCCGCGTTCCTGACC
CCGTACGAGACCGGGCGGCAGTCCGAGGCGAGGCTGAGCTCCGTCCTCGTCGGCCGGGTGGCCGCCCGCCCGGAGCTCGA
GCGGCTGCTCGGGGTCCTCCAGGCGCGGATCGCGGACTGGCACCGCGACTACGCCGACCCGTCCATCGCGGCGGTCCGCC
GGGGGGGCACCGACTCGCCGGGAATCCTCGACCCGGTTCTCGGCAAGACCCGGTTCGACGCGGTGCGCGCCGCGGCCGCG
GACTTCGACGACGCCGTCCGGATCGCCGCGCTGGCGGCCCGTGAGGACGTCACCAACGCACTGCGGACGCTCATCATCTC
GCTCGTCGTGGCCGCGCTGGCGCTCATCGTGCTGCTGGCACTCATCTTCCGAGCGCTGCGGGTGTGGGTGACGCGGCCGC
TGGAGGCCGTCGGCACGGACGTCCGCGAGGTCGCCGCCGGGCACCTGGAGCACGCGGTGGAGTCGGTGGGGCCGCCCGAC
ATCGTCACCCTGGCACGGGACGTCGAATCGATGCGCCTGCAGCTCATCGGTGAGCTCGAGGCCGCGCGCAGGGCGCGGCT
GTCCACCGAGGCGCAGGCGGAGATCCTGCGCCGGTCCAACCGCGACCTGGAGCAGTTCGCCTACGTCGCCTCGCACGACC
TGCAGGAGCCGTTGCGCAAGGTGGCCAGCTTCTGCCAGCTTCTGTCCCGGCGCTACGGCGACCAGCTCGACGAGCGCGGG
ACCCAGTACATCCACTTCGCCGTCGACGGCGCGAAGCGCATGCAGCAGCTCATCAACGACCTGCTCGCCTTCTCCAGGGT
CGGCCGCACCACCGACAGTTTCGTCGACGTCCCGTTGGGCGAGGTCTTCGAGCGGGTGGTGGGGACGCTGTCGCTCGCCC
TGGAGAGCTCCGGCGGCGAGGTGACCGCCAGCGATCTCCCGGCGGTGCCCGGCGACCCCGTTCTGCTGGCCCAGCTCCTG
CAGAACCTGATCGGCAACGCGCTGAAGTTCCGTGGCGACGAGGCCCCGCGGGTGCGGATCGGGGCGATCGACCGCGACGT
CGAGTGGGAGCTGTTCTGCGCGGACAACGGCATCGGCATCGAGCCGGAGTACGCCGAGAAGATCTTCGTGATCTTCCAGC
GCCTGCACGCGCGGGACGTCTACGAGGGCACCGGCATCGGTCTGGCGCTGTGCCGCAAGATCGTCGAGTTCCACGGTGGC
CGGATCTGGCTCGACGGTACGGTGGAGTCCGGGACCGCCTTCCGCTGGACGCTCCCGAAACGCCCGGCCGTGGTCCTGCC
CGCCGACCTTGAGGCGGACGGGGCGCCGCCGGCCTCGGTCACCGGTCCTGTCTCGTCCGCCGGTCCCGGTCCCGGTTCGG
TTGCTGGTCCTGTCGTGGTTGCTGGTCCCGTCGTGGCCGCCGTTCCGCCGAAGTCAGGAGATCGTTCGTGA

Upstream 100 bases:

>100_bases
AACGTAACGGCGGCCCGCTGACCGACGACGTGGCGCTGCTGCTGCTCATCCGTGGGCAGGTCCCGTGAGCGACCAGGCCG
CACCGGCGGTGCTGCGCAGG

Downstream 100 bases:

>100_bases
CCGAGCCCGTTGTCCCGGTCGAGGTCCTGCTGGTCGAGGACGACCCCGGCGACGTCCTGATGACCCGCGAGGCGTTCGAG
GACCACAAGCTCAAGAACAA

Product: multi-sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 556; Mature: 556

Protein sequence:

>556_residues
MRGWRLRRRLAAVYIALSMVLLLAAGIVAWSLVRLDDAIHVRSDVLAPAQTVTVRLTSSLVDQETGMRGYLLQGDPAFLT
PYETGRQSEARLSSVLVGRVAARPELERLLGVLQARIADWHRDYADPSIAAVRRGGTDSPGILDPVLGKTRFDAVRAAAA
DFDDAVRIAALAAREDVTNALRTLIISLVVAALALIVLLALIFRALRVWVTRPLEAVGTDVREVAAGHLEHAVESVGPPD
IVTLARDVESMRLQLIGELEAARRARLSTEAQAEILRRSNRDLEQFAYVASHDLQEPLRKVASFCQLLSRRYGDQLDERG
TQYIHFAVDGAKRMQQLINDLLAFSRVGRTTDSFVDVPLGEVFERVVGTLSLALESSGGEVTASDLPAVPGDPVLLAQLL
QNLIGNALKFRGDEAPRVRIGAIDRDVEWELFCADNGIGIEPEYAEKIFVIFQRLHARDVYEGTGIGLALCRKIVEFHGG
RIWLDGTVESGTAFRWTLPKRPAVVLPADLEADGAPPASVTGPVSSAGPGPGSVAGPVVVAGPVVAAVPPKSGDRS

Sequences:

>Translated_556_residues
MRGWRLRRRLAAVYIALSMVLLLAAGIVAWSLVRLDDAIHVRSDVLAPAQTVTVRLTSSLVDQETGMRGYLLQGDPAFLT
PYETGRQSEARLSSVLVGRVAARPELERLLGVLQARIADWHRDYADPSIAAVRRGGTDSPGILDPVLGKTRFDAVRAAAA
DFDDAVRIAALAAREDVTNALRTLIISLVVAALALIVLLALIFRALRVWVTRPLEAVGTDVREVAAGHLEHAVESVGPPD
IVTLARDVESMRLQLIGELEAARRARLSTEAQAEILRRSNRDLEQFAYVASHDLQEPLRKVASFCQLLSRRYGDQLDERG
TQYIHFAVDGAKRMQQLINDLLAFSRVGRTTDSFVDVPLGEVFERVVGTLSLALESSGGEVTASDLPAVPGDPVLLAQLL
QNLIGNALKFRGDEAPRVRIGAIDRDVEWELFCADNGIGIEPEYAEKIFVIFQRLHARDVYEGTGIGLALCRKIVEFHGG
RIWLDGTVESGTAFRWTLPKRPAVVLPADLEADGAPPASVTGPVSSAGPGPGSVAGPVVVAGPVVAAVPPKSGDRS
>Mature_556_residues
MRGWRLRRRLAAVYIALSMVLLLAAGIVAWSLVRLDDAIHVRSDVLAPAQTVTVRLTSSLVDQETGMRGYLLQGDPAFLT
PYETGRQSEARLSSVLVGRVAARPELERLLGVLQARIADWHRDYADPSIAAVRRGGTDSPGILDPVLGKTRFDAVRAAAA
DFDDAVRIAALAAREDVTNALRTLIISLVVAALALIVLLALIFRALRVWVTRPLEAVGTDVREVAAGHLEHAVESVGPPD
IVTLARDVESMRLQLIGELEAARRARLSTEAQAEILRRSNRDLEQFAYVASHDLQEPLRKVASFCQLLSRRYGDQLDERG
TQYIHFAVDGAKRMQQLINDLLAFSRVGRTTDSFVDVPLGEVFERVVGTLSLALESSGGEVTASDLPAVPGDPVLLAQLL
QNLIGNALKFRGDEAPRVRIGAIDRDVEWELFCADNGIGIEPEYAEKIFVIFQRLHARDVYEGTGIGLALCRKIVEFHGG
RIWLDGTVESGTAFRWTLPKRPAVVLPADLEADGAPPASVTGPVSSAGPGPGSVAGPVVVAGPVVAAVPPKSGDRS

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Integral Membrane Protein. Inner Membrane [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=420, Percent_Identity=25.4761904761905, Blast_Score=86, Evalue=8e-18,
Organism=Escherichia coli, GI1786912, Length=306, Percent_Identity=29.7385620915033, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1790346, Length=199, Percent_Identity=29.6482412060301, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI87081816, Length=345, Percent_Identity=25.7971014492754, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1788713, Length=228, Percent_Identity=26.3157894736842, Blast_Score=69, Evalue=6e-13,
Organism=Escherichia coli, GI1786600, Length=305, Percent_Identity=26.8852459016393, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI48994928, Length=234, Percent_Identity=26.4957264957265, Blast_Score=67, Evalue=4e-12,
Organism=Escherichia coli, GI1790861, Length=315, Percent_Identity=26.031746031746, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1788549, Length=223, Percent_Identity=26.9058295964126, Blast_Score=62, Evalue=7e-11,
Organism=Escherichia coli, GI1790300, Length=273, Percent_Identity=27.4725274725275, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003018
- InterPro:   IPR013654
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01590 GAF; PF02518 HATPase_c; PF00512 HisKA; PF08446 PAS_2; PF00360 Phytochrome [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 60034; Mature: 60034

Theoretical pI: Translated: 5.95; Mature: 5.95

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRGWRLRRRLAAVYIALSMVLLLAAGIVAWSLVRLDDAIHVRSDVLAPAQTVTVRLTSSL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEHHHHH
VDQETGMRGYLLQGDPAFLTPYETGRQSEARLSSVLVGRVAARPELERLLGVLQARIADW
HHHHCCCCCEEEECCCCEECCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
HRDYADPSIAAVRRGGTDSPGILDPVLGKTRFDAVRAAAADFDDAVRIAALAAREDVTNA
HHHHCCCHHHHHHCCCCCCCCCCHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
LRTLIISLVVAALALIVLLALIFRALRVWVTRPLEAVGTDVREVAAGHLEHAVESVGPPD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHCCCCH
IVTLARDVESMRLQLIGELEAARRARLSTEAQAEILRRSNRDLEQFAYVASHDLQEPLRK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
VASFCQLLSRRYGDQLDERGTQYIHFAVDGAKRMQQLINDLLAFSRVGRTTDSFVDVPLG
HHHHHHHHHHHHCCHHHHCCCEEEEEEECHHHHHHHHHHHHHHHHHCCCCCCHHHCCCHH
EVFERVVGTLSLALESSGGEVTASDLPAVPGDPVLLAQLLQNLIGNALKFRGDEAPRVRI
HHHHHHHHHHHHHEECCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEE
GAIDRDVEWELFCADNGIGIEPEYAEKIFVIFQRLHARDVYEGTGIGLALCRKIVEFHGG
ECCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC
RIWLDGTVESGTAFRWTLPKRPAVVLPADLEADGAPPASVTGPVSSAGPGPGSVAGPVVV
EEEEECEECCCCEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEE
AGPVVAAVPPKSGDRS
ECCEEEECCCCCCCCC
>Mature Secondary Structure
MRGWRLRRRLAAVYIALSMVLLLAAGIVAWSLVRLDDAIHVRSDVLAPAQTVTVRLTSSL
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEEEEHHHHH
VDQETGMRGYLLQGDPAFLTPYETGRQSEARLSSVLVGRVAARPELERLLGVLQARIADW
HHHHCCCCCEEEECCCCEECCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
HRDYADPSIAAVRRGGTDSPGILDPVLGKTRFDAVRAAAADFDDAVRIAALAAREDVTNA
HHHHCCCHHHHHHCCCCCCCCCCHHHHCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHH
LRTLIISLVVAALALIVLLALIFRALRVWVTRPLEAVGTDVREVAAGHLEHAVESVGPPD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHCCCCH
IVTLARDVESMRLQLIGELEAARRARLSTEAQAEILRRSNRDLEQFAYVASHDLQEPLRK
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
VASFCQLLSRRYGDQLDERGTQYIHFAVDGAKRMQQLINDLLAFSRVGRTTDSFVDVPLG
HHHHHHHHHHHHCCHHHHCCCEEEEEEECHHHHHHHHHHHHHHHHHCCCCCCHHHCCCHH
EVFERVVGTLSLALESSGGEVTASDLPAVPGDPVLLAQLLQNLIGNALKFRGDEAPRVRI
HHHHHHHHHHHHHEECCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEE
GAIDRDVEWELFCADNGIGIEPEYAEKIFVIFQRLHARDVYEGTGIGLALCRKIVEFHGG
ECCCCCCCEEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHCCC
RIWLDGTVESGTAFRWTLPKRPAVVLPADLEADGAPPASVTGPVSSAGPGPGSVAGPVVV
EEEEECEECCCCEEEEECCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEE
AGPVVAAVPPKSGDRS
ECCEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11759840 [H]