| Definition | Frankia sp. EAN1pec chromosome, complete genome. |
|---|---|
| Accession | NC_009921 |
| Length | 8,982,042 |
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The map label for this gene is gno [H]
Identifier: 158318178
GI number: 158318178
Start: 7834192
End: 7834953
Strand: Direct
Name: gno [H]
Synonym: Franean1_6443
Alternate gene names: 158318178
Gene position: 7834192-7834953 (Clockwise)
Preceding gene: 158318176
Following gene: 158318180
Centisome position: 87.22
GC content: 72.44
Gene sequence:
>762_bases ATGTCGGTATTGGACAGATTCCGCCTCGACGGCAGGGTCGCCATCGTCACCGGGGCCTCGTCGGGGATCGGCGTCGGCTT CGCCCGCGGGCTCGCCCAGGCCGGCGCGGACGTCACTCTCGGTGCCCGGCGCACCGACCGGCTCGCCGCGACCGCCGCGC TGGTCGAGGCGGAAGGCCGCCGGGCCGCCGCCGTCGGCACCGACGTGGCCGACCCGGAGTCGTGCCGGAACCTCGTCACG GCCGCCATGGACACCTTCGGGCGGGTCGACATCCTGGTCAACAACGCCGGGGTCGGTTCGGCCCACCCGGCGCTGCGGGA GACCCCGGAGCAGTTCCGCTCGGTCATCGACGTCAACCTCAACGGCTGCTACTGGATGGCCCAGGCCGCCGCGGCCGTCA TGCAGCCGGGCAGCAGCATCATCAACATCTCCAGCGTGCTCGGCCTGACGACGGCCGGCCTCCCGCAGGCCGCCTATTCG GCCAGTAAGGCGGCCCTGCTCGGGCTGACCCGCGACCTCGCCCAGCAGTGGACGGGCCGGCGCGGGATCCGCGTGAACGC CCTGGCCCCCGGGTTCTTCGAGTCCGAGATGACCGACCAGTACCTGCCCGGGTACCTGGAGAGCCAGTCGGCACGGATCC TCGCCGGCCGCTTCGGCGACCTTGAGGAGCTGACCGCCGCGCTGGTCTTCCTCGCCTCCGACGCCGGCGGCTACGTCACC GGACAGACCCTCGTCGTCGACGGCGGTGTCTCCATCACCTGA
Upstream 100 bases:
>100_bases GAGAATCCTGAGATCCGGGACGCGTGCGCCGAGCTCACCCAGCGGGCACGCGCCGTCCGTCCGGGTATGTCATCGCCGGT CACACGAAGGCGGAGAACAG
Downstream 100 bases:
>100_bases CCGCGCTGCTCAGGGAGCCGGTCAGGTCTCCAACGGCATGAGCTCGCGGGCGAACCCCTCGAGGAACTCCGGCCAGCCGG CGGAGTCGATCAGCGGGTAC
Product: short-chain dehydrogenase/reductase SDR
Products: NA
Alternate protein names: 5-keto-D-gluconate 5-reductase [H]
Number of amino acids: Translated: 253; Mature: 252
Protein sequence:
>253_residues MSVLDRFRLDGRVAIVTGASSGIGVGFARGLAQAGADVTLGARRTDRLAATAALVEAEGRRAAAVGTDVADPESCRNLVT AAMDTFGRVDILVNNAGVGSAHPALRETPEQFRSVIDVNLNGCYWMAQAAAAVMQPGSSIINISSVLGLTTAGLPQAAYS ASKAALLGLTRDLAQQWTGRRGIRVNALAPGFFESEMTDQYLPGYLESQSARILAGRFGDLEELTAALVFLASDAGGYVT GQTLVVDGGVSIT
Sequences:
>Translated_253_residues MSVLDRFRLDGRVAIVTGASSGIGVGFARGLAQAGADVTLGARRTDRLAATAALVEAEGRRAAAVGTDVADPESCRNLVT AAMDTFGRVDILVNNAGVGSAHPALRETPEQFRSVIDVNLNGCYWMAQAAAAVMQPGSSIINISSVLGLTTAGLPQAAYS ASKAALLGLTRDLAQQWTGRRGIRVNALAPGFFESEMTDQYLPGYLESQSARILAGRFGDLEELTAALVFLASDAGGYVT GQTLVVDGGVSIT >Mature_252_residues SVLDRFRLDGRVAIVTGASSGIGVGFARGLAQAGADVTLGARRTDRLAATAALVEAEGRRAAAVGTDVADPESCRNLVTA AMDTFGRVDILVNNAGVGSAHPALRETPEQFRSVIDVNLNGCYWMAQAAAAVMQPGSSIINISSVLGLTTAGLPQAAYSA SKAALLGLTRDLAQQWTGRRGIRVNALAPGFFESEMTDQYLPGYLESQSARILAGRFGDLEELTAALVFLASDAGGYVTG QTLVVDGGVSIT
Specific function: Involved in the non-phosphorylative, ketogenic oxidation of glucose and oxidizes gluconate to 5-ketogluconate. Dependent on NADP, almost inactive with NAD [H]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI19923817, Length=256, Percent_Identity=33.984375, Blast_Score=142, Evalue=3e-34, Organism=Homo sapiens, GI40254992, Length=252, Percent_Identity=36.9047619047619, Blast_Score=119, Evalue=2e-27, Organism=Homo sapiens, GI15277342, Length=256, Percent_Identity=36.328125, Blast_Score=115, Evalue=3e-26, Organism=Homo sapiens, GI32483357, Length=250, Percent_Identity=32.4, Blast_Score=113, Evalue=1e-25, Organism=Homo sapiens, GI10190704, Length=251, Percent_Identity=33.8645418326693, Blast_Score=112, Evalue=5e-25, Organism=Homo sapiens, GI4503301, Length=251, Percent_Identity=29.4820717131474, Blast_Score=102, Evalue=3e-22, Organism=Homo sapiens, GI5031737, Length=248, Percent_Identity=30.241935483871, Blast_Score=96, Evalue=4e-20, Organism=Homo sapiens, GI31542939, Length=212, Percent_Identity=34.9056603773585, Blast_Score=94, Evalue=1e-19, Organism=Homo sapiens, GI7705925, Length=247, Percent_Identity=34.412955465587, Blast_Score=93, Evalue=2e-19, Organism=Homo sapiens, GI126723750, Length=250, Percent_Identity=30.4, Blast_Score=89, Evalue=3e-18, Organism=Homo sapiens, GI66933014, Length=253, Percent_Identity=30.0395256916996, Blast_Score=87, Evalue=1e-17, Organism=Homo sapiens, GI33667109, Length=200, Percent_Identity=32, Blast_Score=85, Evalue=8e-17, Organism=Homo sapiens, GI224922801, Length=177, Percent_Identity=36.1581920903955, Blast_Score=83, Evalue=2e-16, Organism=Homo sapiens, GI4504505, Length=207, Percent_Identity=35.2657004830918, Blast_Score=83, Evalue=3e-16, Organism=Homo sapiens, GI59889578, Length=237, Percent_Identity=31.6455696202532, Blast_Score=82, Evalue=3e-16, Organism=Homo sapiens, GI7706318, Length=204, Percent_Identity=29.4117647058824, Blast_Score=80, Evalue=2e-15, Organism=Homo sapiens, GI209862901, Length=203, Percent_Identity=31.0344827586207, Blast_Score=78, Evalue=1e-14, Organism=Homo sapiens, GI19923983, Length=203, Percent_Identity=31.0344827586207, Blast_Score=78, Evalue=1e-14, Organism=Homo sapiens, GI126723191, Length=184, Percent_Identity=33.1521739130435, Blast_Score=77, Evalue=1e-14, Organism=Homo sapiens, GI4758504, Length=268, Percent_Identity=27.9850746268657, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI40254986, Length=193, Percent_Identity=31.6062176165803, Blast_Score=74, Evalue=2e-13, Organism=Homo sapiens, GI225579078, Length=205, Percent_Identity=30.7317073170732, Blast_Score=71, Evalue=7e-13, Organism=Homo sapiens, GI109715829, Length=238, Percent_Identity=26.890756302521, Blast_Score=68, Evalue=8e-12, Organism=Escherichia coli, GI1789208, Length=254, Percent_Identity=39.3700787401575, Blast_Score=148, Evalue=3e-37, Organism=Escherichia coli, GI87082160, Length=250, Percent_Identity=36.8, Blast_Score=142, Evalue=3e-35, Organism=Escherichia coli, GI1787335, Length=250, Percent_Identity=37.6, Blast_Score=140, Evalue=1e-34, Organism=Escherichia coli, GI1790717, Length=259, Percent_Identity=34.7490347490347, Blast_Score=125, Evalue=3e-30, Organism=Escherichia coli, GI87082100, Length=255, Percent_Identity=35.2941176470588, Blast_Score=120, Evalue=6e-29, Organism=Escherichia coli, GI1788459, Length=244, Percent_Identity=37.2950819672131, Blast_Score=114, Evalue=7e-27, Organism=Escherichia coli, GI1789378, Length=252, Percent_Identity=33.3333333333333, Blast_Score=108, Evalue=3e-25, Organism=Escherichia coli, GI1787905, Length=253, Percent_Identity=32.8063241106719, Blast_Score=96, Evalue=2e-21, Organism=Escherichia coli, GI2367365, Length=241, Percent_Identity=32.7800829875519, Blast_Score=87, Evalue=8e-19, Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=31.4285714285714, Blast_Score=84, Evalue=7e-18, Organism=Escherichia coli, GI1787526, Length=190, Percent_Identity=32.1052631578947, Blast_Score=74, Evalue=7e-15, Organism=Escherichia coli, GI1786812, Length=256, Percent_Identity=28.125, Blast_Score=74, Evalue=8e-15, Organism=Escherichia coli, GI1789057, Length=255, Percent_Identity=29.4117647058824, Blast_Score=69, Evalue=2e-13, Organism=Caenorhabditis elegans, GI25147288, Length=248, Percent_Identity=37.0967741935484, Blast_Score=132, Evalue=2e-31, Organism=Caenorhabditis elegans, GI17555706, Length=245, Percent_Identity=34.6938775510204, Blast_Score=130, Evalue=8e-31, Organism=Caenorhabditis elegans, GI17560676, Length=247, Percent_Identity=30.3643724696356, Blast_Score=118, Evalue=3e-27, Organism=Caenorhabditis elegans, GI17560332, Length=265, Percent_Identity=32.8301886792453, Blast_Score=114, Evalue=7e-26, Organism=Caenorhabditis elegans, GI71994600, Length=249, Percent_Identity=32.9317269076305, Blast_Score=112, Evalue=2e-25, Organism=Caenorhabditis elegans, GI17561402, Length=253, Percent_Identity=30.0395256916996, Blast_Score=111, Evalue=3e-25, Organism=Caenorhabditis elegans, GI193204405, Length=263, Percent_Identity=31.9391634980989, Blast_Score=111, Evalue=3e-25, Organism=Caenorhabditis elegans, GI72000259, Length=261, Percent_Identity=31.8007662835249, Blast_Score=110, Evalue=5e-25, Organism=Caenorhabditis elegans, GI17562906, Length=269, Percent_Identity=33.8289962825279, Blast_Score=107, Evalue=5e-24, Organism=Caenorhabditis elegans, GI17562910, Length=263, Percent_Identity=29.6577946768061, Blast_Score=106, Evalue=9e-24, Organism=Caenorhabditis elegans, GI17560150, Length=265, Percent_Identity=30.9433962264151, Blast_Score=104, Evalue=4e-23, Organism=Caenorhabditis elegans, GI71994604, Length=248, Percent_Identity=31.8548387096774, Blast_Score=102, Evalue=1e-22, Organism=Caenorhabditis elegans, GI17562990, Length=265, Percent_Identity=30.188679245283, Blast_Score=101, Evalue=3e-22, Organism=Caenorhabditis elegans, GI17562904, Length=270, Percent_Identity=30, Blast_Score=100, Evalue=7e-22, Organism=Caenorhabditis elegans, GI17538480, Length=265, Percent_Identity=32.4528301886792, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17531453, Length=267, Percent_Identity=31.8352059925094, Blast_Score=100, Evalue=1e-21, Organism=Caenorhabditis elegans, GI17562908, Length=267, Percent_Identity=31.0861423220974, Blast_Score=97, Evalue=6e-21, Organism=Caenorhabditis elegans, GI17563726, Length=266, Percent_Identity=28.9473684210526, Blast_Score=97, Evalue=8e-21, Organism=Caenorhabditis elegans, GI17559104, Length=263, Percent_Identity=29.6577946768061, Blast_Score=96, Evalue=1e-20, Organism=Caenorhabditis elegans, GI17538486, Length=265, Percent_Identity=31.3207547169811, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI17544670, Length=264, Percent_Identity=27.2727272727273, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI17560220, Length=264, Percent_Identity=31.0606060606061, Blast_Score=94, Evalue=5e-20, Organism=Caenorhabditis elegans, GI17551412, Length=264, Percent_Identity=30.3030303030303, Blast_Score=94, Evalue=7e-20, Organism=Caenorhabditis elegans, GI115534694, Length=250, Percent_Identity=34.4, Blast_Score=92, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17536025, Length=257, Percent_Identity=30.3501945525292, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17568967, Length=208, Percent_Identity=33.6538461538462, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17565030, Length=264, Percent_Identity=31.0606060606061, Blast_Score=87, Evalue=1e-17, Organism=Caenorhabditis elegans, GI17561272, Length=257, Percent_Identity=30.3501945525292, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17538182, Length=258, Percent_Identity=31.0077519379845, Blast_Score=81, Evalue=5e-16, Organism=Caenorhabditis elegans, GI17536651, Length=256, Percent_Identity=28.90625, Blast_Score=80, Evalue=1e-15, Organism=Caenorhabditis elegans, GI17508651, Length=255, Percent_Identity=28.2352941176471, Blast_Score=70, Evalue=1e-12, Organism=Caenorhabditis elegans, GI17555612, Length=212, Percent_Identity=30.6603773584906, Blast_Score=69, Evalue=3e-12, Organism=Caenorhabditis elegans, GI17570069, Length=170, Percent_Identity=28.8235294117647, Blast_Score=68, Evalue=4e-12, Organism=Caenorhabditis elegans, GI71982365, Length=194, Percent_Identity=29.8969072164948, Blast_Score=67, Evalue=1e-11, Organism=Caenorhabditis elegans, GI17564282, Length=200, Percent_Identity=25.5, Blast_Score=65, Evalue=3e-11, Organism=Caenorhabditis elegans, GI17508895, Length=203, Percent_Identity=24.6305418719212, Blast_Score=65, Evalue=4e-11, Organism=Caenorhabditis elegans, GI17567345, Length=195, Percent_Identity=27.6923076923077, Blast_Score=64, Evalue=8e-11, Organism=Saccharomyces cerevisiae, GI6322861, Length=207, Percent_Identity=35.2657004830918, Blast_Score=99, Evalue=5e-22, Organism=Saccharomyces cerevisiae, GI6324126, Length=254, Percent_Identity=29.5275590551181, Blast_Score=87, Evalue=3e-18, Organism=Saccharomyces cerevisiae, GI6323882, Length=201, Percent_Identity=29.3532338308458, Blast_Score=67, Evalue=2e-12, Organism=Drosophila melanogaster, GI21355319, Length=249, Percent_Identity=33.3333333333333, Blast_Score=130, Evalue=1e-30, Organism=Drosophila melanogaster, GI21357041, Length=248, Percent_Identity=36.2903225806452, Blast_Score=124, Evalue=6e-29, Organism=Drosophila melanogaster, GI28571526, Length=247, Percent_Identity=34.412955465587, Blast_Score=116, Evalue=1e-26, Organism=Drosophila melanogaster, GI24644339, Length=249, Percent_Identity=32.5301204819277, Blast_Score=112, Evalue=2e-25, Organism=Drosophila melanogaster, GI23397609, Length=251, Percent_Identity=33.4661354581673, Blast_Score=111, Evalue=6e-25, Organism=Drosophila melanogaster, GI24639444, Length=248, Percent_Identity=33.4677419354839, Blast_Score=108, Evalue=5e-24, Organism=Drosophila melanogaster, GI24643142, Length=247, Percent_Identity=32.3886639676113, Blast_Score=103, Evalue=1e-22, Organism=Drosophila melanogaster, GI24644337, Length=253, Percent_Identity=32.0158102766798, Blast_Score=95, Evalue=5e-20, Organism=Drosophila melanogaster, GI18859837, Length=214, Percent_Identity=34.5794392523364, Blast_Score=84, Evalue=1e-16, Organism=Drosophila melanogaster, GI17737361, Length=200, Percent_Identity=33, Blast_Score=80, Evalue=1e-15, Organism=Drosophila melanogaster, GI116007236, Length=201, Percent_Identity=31.3432835820896, Blast_Score=79, Evalue=4e-15, Organism=Drosophila melanogaster, GI24641232, Length=201, Percent_Identity=30.3482587064677, Blast_Score=76, Evalue=2e-14, Organism=Drosophila melanogaster, GI24641388, Length=211, Percent_Identity=30.3317535545024, Blast_Score=75, Evalue=4e-14, Organism=Drosophila melanogaster, GI116007234, Length=205, Percent_Identity=35.1219512195122, Blast_Score=75, Evalue=4e-14, Organism=Drosophila melanogaster, GI21358495, Length=206, Percent_Identity=31.5533980582524, Blast_Score=75, Evalue=5e-14, Organism=Drosophila melanogaster, GI21357673, Length=197, Percent_Identity=29.4416243654822, Blast_Score=71, Evalue=8e-13, Organism=Drosophila melanogaster, GI116007238, Length=179, Percent_Identity=32.9608938547486, Blast_Score=69, Evalue=2e-12, Organism=Drosophila melanogaster, GI28571387, Length=204, Percent_Identity=29.4117647058824, Blast_Score=68, Evalue=5e-12, Organism=Drosophila melanogaster, GI116007232, Length=186, Percent_Identity=36.0215053763441, Blast_Score=67, Evalue=2e-11, Organism=Drosophila melanogaster, GI221331218, Length=197, Percent_Identity=29.4416243654822, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI24665243, Length=198, Percent_Identity=28.2828282828283, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI24663911, Length=213, Percent_Identity=26.7605633802817, Blast_Score=66, Evalue=2e-11, Organism=Drosophila melanogaster, GI221331216, Length=197, Percent_Identity=28.9340101522843, Blast_Score=65, Evalue=3e-11, Organism=Drosophila melanogaster, GI24586328, Length=202, Percent_Identity=29.2079207920792, Blast_Score=65, Evalue=3e-11, Organism=Drosophila melanogaster, GI24665247, Length=198, Percent_Identity=27.7777777777778, Blast_Score=65, Evalue=4e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.69 [H]
Molecular weight: Translated: 26164; Mature: 26033
Theoretical pI: Translated: 4.84; Mature: 4.84
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
0.8 %Cys (Translated Protein) 2.0 %Met (Translated Protein) 2.8 %Cys+Met (Translated Protein) 0.8 %Cys (Mature Protein) 1.6 %Met (Mature Protein) 2.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MSVLDRFRLDGRVAIVTGASSGIGVGFARGLAQAGADVTLGARRTDRLAATAALVEAEGR CCHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHCCCC RAAAVGTDVADPESCRNLVTAAMDTFGRVDILVNNAGVGSAHPALRETPEQFRSVIDVNL EEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHCCHHHHHHHEECCC NGCYWMAQAAAAVMQPGSSIINISSVLGLTTAGLPQAAYSASKAALLGLTRDLAQQWTGR CCCHHHHHHHHHHHCCCCCEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC RGIRVNALAPGFFESEMTDQYLPGYLESQSARILAGRFGDLEELTAALVFLASDAGGYVT CCEEEEEECCCCHHHHCCHHHCCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCEEE GQTLVVDGGVSIT CCEEEEECCCCCC >Mature Secondary Structure SVLDRFRLDGRVAIVTGASSGIGVGFARGLAQAGADVTLGARRTDRLAATAALVEAEGR CHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHCCCCEEECCCCHHHHHHHHHHHHCCCC RAAAVGTDVADPESCRNLVTAAMDTFGRVDILVNNAGVGSAHPALRETPEQFRSVIDVNL EEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCHHHCCHHHHHHHEECCC NGCYWMAQAAAAVMQPGSSIINISSVLGLTTAGLPQAAYSASKAALLGLTRDLAQQWTGR CCCHHHHHHHHHHHCCCCCEEEHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCC RGIRVNALAPGFFESEMTDQYLPGYLESQSARILAGRFGDLEELTAALVFLASDAGGYVT CCEEEEEECCCCHHHHCCHHHCCCCCCCCCCEEEECCCCCHHHHHHHHHHHCCCCCCEEE GQTLVVDGGVSIT CCEEEEECCCCCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 7751271 [H]