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The map label for this gene is acdA [H]

Identifier: 158318151

GI number: 158318151

Start: 7790747

End: 7791892

Strand: Direct

Name: acdA [H]

Synonym: Franean1_6416

Alternate gene names: 158318151

Gene position: 7790747-7791892 (Clockwise)

Preceding gene: 158318145

Following gene: 158318152

Centisome position: 86.74

GC content: 71.64

Gene sequence:

>1146_bases
ATGCCCGCCGAACGGCAGCTCCCCTCATCGGAAGCGCGGGAGCTGATCGAGCTCACCGCCACCATGTGCGACCGCGAGCT
TGCTCCGAGAGTCACGGAGTACGAGGCCGCCAGCCGCTTCCCGCGCGAGGAGTTCGCGGTGCTCGGCAAGGCCGGGCTGC
TGAGCCTGCCGTACCCGGAGAGCTTCGGCGGCGGCGAGCAGCCGTACGAGGTGTACCTACAGGTGCTGGAGGAGATCTCC
TACCGCTGGGCGGCCGTGGCGGTCGGGGTGAGCGTGCACGCGCTGTCCTGCTACCCGCTGGCGACCTTCGGCACCCCGGA
GCAGCAGGAGGAGCACCTTCCCCGGCTGCTGTCCGGTGACCTGCTCGGCGCCTACTGCCTGTCCGAGGCGCACGCGGGGT
CGGACCCGGCGGCGATGCGCGTGACGGCCACCGCCACCGACGACGGCTACCTGCTCAACGGCACGAAGGCGTGGGTGACC
CACGGCGGCGCCGCCGACTTCTACACGGTCTTCGCGCGGACGTCGTCCGACACCCGCGGCGGGATCTCCTGCTTCCTCGT
CGACGCGGGCACGCCCAACATCAGGTTCCACCCGCCCGAGAAGAAGATGGGGCTGACCGCGTCACCGACGACGCAGATCA
GTTTCGACGACGTCGCGGTCCCGGCGTCGCGCCTGATCGGCAAGGTGGGGCAGGGCCTGTCGATCGCGCTGTCGGCCCTC
GACTCGGGCCGGCTCGGGATCGCCGCCACCGCCGTCGGGCTCGGGCAGCGCGCGCTGGACGACGCCGTCGCGTACGCGAA
GGAGCGGGAGGCGTTCGGGAAGGCGATCATCGACCATCAGGGGCTCGGCTTCCTGCTGGCCGACATGGCGGCCGCCGTCG
AGTCCGCGCGGGCCACCACCCTGGCCGCCGCCCGGCGCCGGGACGCCGGACTGCAGTACGGGCGCGCCGCGTCCGTCGCA
AAGCTCGTCGCAACGGACGCGGCCATGAAGGTCACCGAGGACGCCGTGCAGGTCCTCGGCGGCGCCGGCTACACCAAGGA
CTTCCCGGTGGAGCGGTACATGCGCGAGGCGAAGGTGATGCAGATCTTCGAGGGAACCAACCAGATCCAGCGCCTCGTCA
TCAGCCGCCACCTCGCCCGCGGCTGA

Upstream 100 bases:

>100_bases
CCGAGACGGACGGATCCGGCACCGACGGAGACGATCGCGCGCGGGGGTTCCGGCTCCACGCGGCGCGAGGGCGATGACCG
ACGAAGCACGGGAGGACACC

Downstream 100 bases:

>100_bases
CCAGCCGGGCGCGGTGGCGGAGGTCAGGGCAGGACGGAACCCGCCCGGGACGGAGGTCTCACAGACCTCATATCTGGTGC
CCATACGGTGCATCCTCGCC

Product: acyl-CoA dehydrogenase domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 381; Mature: 380

Protein sequence:

>381_residues
MPAERQLPSSEARELIELTATMCDRELAPRVTEYEAASRFPREEFAVLGKAGLLSLPYPESFGGGEQPYEVYLQVLEEIS
YRWAAVAVGVSVHALSCYPLATFGTPEQQEEHLPRLLSGDLLGAYCLSEAHAGSDPAAMRVTATATDDGYLLNGTKAWVT
HGGAADFYTVFARTSSDTRGGISCFLVDAGTPNIRFHPPEKKMGLTASPTTQISFDDVAVPASRLIGKVGQGLSIALSAL
DSGRLGIAATAVGLGQRALDDAVAYAKEREAFGKAIIDHQGLGFLLADMAAAVESARATTLAAARRRDAGLQYGRAASVA
KLVATDAAMKVTEDAVQVLGGAGYTKDFPVERYMREAKVMQIFEGTNQIQRLVISRHLARG

Sequences:

>Translated_381_residues
MPAERQLPSSEARELIELTATMCDRELAPRVTEYEAASRFPREEFAVLGKAGLLSLPYPESFGGGEQPYEVYLQVLEEIS
YRWAAVAVGVSVHALSCYPLATFGTPEQQEEHLPRLLSGDLLGAYCLSEAHAGSDPAAMRVTATATDDGYLLNGTKAWVT
HGGAADFYTVFARTSSDTRGGISCFLVDAGTPNIRFHPPEKKMGLTASPTTQISFDDVAVPASRLIGKVGQGLSIALSAL
DSGRLGIAATAVGLGQRALDDAVAYAKEREAFGKAIIDHQGLGFLLADMAAAVESARATTLAAARRRDAGLQYGRAASVA
KLVATDAAMKVTEDAVQVLGGAGYTKDFPVERYMREAKVMQIFEGTNQIQRLVISRHLARG
>Mature_380_residues
PAERQLPSSEARELIELTATMCDRELAPRVTEYEAASRFPREEFAVLGKAGLLSLPYPESFGGGEQPYEVYLQVLEEISY
RWAAVAVGVSVHALSCYPLATFGTPEQQEEHLPRLLSGDLLGAYCLSEAHAGSDPAAMRVTATATDDGYLLNGTKAWVTH
GGAADFYTVFARTSSDTRGGISCFLVDAGTPNIRFHPPEKKMGLTASPTTQISFDDVAVPASRLIGKVGQGLSIALSALD
SGRLGIAATAVGLGQRALDDAVAYAKEREAFGKAIIDHQGLGFLLADMAAAVESARATTLAAARRRDAGLQYGRAASVAK
LVATDAAMKVTEDAVQVLGGAGYTKDFPVERYMREAKVMQIFEGTNQIQRLVISRHLARG

Specific function: Involved in the degradation of long-chain fatty acids [H]

COG id: COG1960

COG function: function code I; Acyl-CoA dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl-CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4557233, Length=377, Percent_Identity=39.7877984084881, Blast_Score=265, Evalue=5e-71,
Organism=Homo sapiens, GI187960098, Length=357, Percent_Identity=38.655462184874, Blast_Score=254, Evalue=8e-68,
Organism=Homo sapiens, GI4557231, Length=357, Percent_Identity=38.655462184874, Blast_Score=254, Evalue=1e-67,
Organism=Homo sapiens, GI4501859, Length=356, Percent_Identity=36.7977528089888, Blast_Score=238, Evalue=1e-62,
Organism=Homo sapiens, GI226958412, Length=374, Percent_Identity=33.9572192513369, Blast_Score=222, Evalue=4e-58,
Organism=Homo sapiens, GI7656849, Length=390, Percent_Identity=33.3333333333333, Blast_Score=221, Evalue=7e-58,
Organism=Homo sapiens, GI226958414, Length=340, Percent_Identity=34.7058823529412, Blast_Score=207, Evalue=9e-54,
Organism=Homo sapiens, GI21361497, Length=349, Percent_Identity=34.0974212034384, Blast_Score=204, Evalue=2e-52,
Organism=Homo sapiens, GI76496475, Length=341, Percent_Identity=33.7243401759531, Blast_Score=203, Evalue=2e-52,
Organism=Homo sapiens, GI4557235, Length=341, Percent_Identity=33.7243401759531, Blast_Score=203, Evalue=3e-52,
Organism=Homo sapiens, GI4501857, Length=363, Percent_Identity=30.5785123966942, Blast_Score=162, Evalue=5e-40,
Organism=Homo sapiens, GI4503943, Length=377, Percent_Identity=29.1777188328912, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI7669494, Length=369, Percent_Identity=29.5392953929539, Blast_Score=134, Evalue=1e-31,
Organism=Homo sapiens, GI38505218, Length=282, Percent_Identity=29.4326241134752, Blast_Score=121, Evalue=8e-28,
Organism=Homo sapiens, GI48976061, Length=291, Percent_Identity=28.5223367697594, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI211971008, Length=291, Percent_Identity=28.5223367697594, Blast_Score=107, Evalue=3e-23,
Organism=Escherichia coli, GI87081958, Length=347, Percent_Identity=30.5475504322767, Blast_Score=148, Evalue=6e-37,
Organism=Escherichia coli, GI1786223, Length=384, Percent_Identity=27.6041666666667, Blast_Score=127, Evalue=9e-31,
Organism=Escherichia coli, GI87082384, Length=298, Percent_Identity=28.5234899328859, Blast_Score=93, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI17569725, Length=375, Percent_Identity=37.6, Blast_Score=256, Evalue=2e-68,
Organism=Caenorhabditis elegans, GI17534899, Length=357, Percent_Identity=37.5350140056022, Blast_Score=247, Evalue=9e-66,
Organism=Caenorhabditis elegans, GI17570075, Length=357, Percent_Identity=36.1344537815126, Blast_Score=238, Evalue=3e-63,
Organism=Caenorhabditis elegans, GI17508101, Length=378, Percent_Identity=33.8624338624339, Blast_Score=235, Evalue=3e-62,
Organism=Caenorhabditis elegans, GI17506239, Length=327, Percent_Identity=37.0030581039755, Blast_Score=233, Evalue=2e-61,
Organism=Caenorhabditis elegans, GI17533517, Length=374, Percent_Identity=34.2245989304813, Blast_Score=228, Evalue=3e-60,
Organism=Caenorhabditis elegans, GI17538396, Length=361, Percent_Identity=34.9030470914127, Blast_Score=226, Evalue=2e-59,
Organism=Caenorhabditis elegans, GI71985184, Length=393, Percent_Identity=30.5343511450382, Blast_Score=184, Evalue=5e-47,
Organism=Caenorhabditis elegans, GI71990804, Length=277, Percent_Identity=36.8231046931408, Blast_Score=181, Evalue=7e-46,
Organism=Caenorhabditis elegans, GI17551932, Length=362, Percent_Identity=28.7292817679558, Blast_Score=168, Evalue=5e-42,
Organism=Caenorhabditis elegans, GI17505929, Length=364, Percent_Identity=29.3956043956044, Blast_Score=163, Evalue=1e-40,
Organism=Caenorhabditis elegans, GI17534353, Length=371, Percent_Identity=28.5714285714286, Blast_Score=161, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI32563615, Length=240, Percent_Identity=35.4166666666667, Blast_Score=157, Evalue=7e-39,
Organism=Caenorhabditis elegans, GI71985192, Length=328, Percent_Identity=29.2682926829268, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI71982178, Length=273, Percent_Identity=29.3040293040293, Blast_Score=129, Evalue=3e-30,
Organism=Caenorhabditis elegans, GI17531909, Length=242, Percent_Identity=28.099173553719, Blast_Score=117, Evalue=8e-27,
Organism=Caenorhabditis elegans, GI17531913, Length=176, Percent_Identity=28.4090909090909, Blast_Score=88, Evalue=8e-18,
Organism=Caenorhabditis elegans, GI17562446, Length=287, Percent_Identity=24.390243902439, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI21356377, Length=378, Percent_Identity=37.3015873015873, Blast_Score=250, Evalue=9e-67,
Organism=Drosophila melanogaster, GI24660351, Length=371, Percent_Identity=37.466307277628, Blast_Score=249, Evalue=2e-66,
Organism=Drosophila melanogaster, GI24646207, Length=373, Percent_Identity=38.0697050938338, Blast_Score=245, Evalue=3e-65,
Organism=Drosophila melanogaster, GI24666513, Length=382, Percent_Identity=31.6753926701571, Blast_Score=219, Evalue=2e-57,
Organism=Drosophila melanogaster, GI21355753, Length=376, Percent_Identity=34.3085106382979, Blast_Score=210, Evalue=1e-54,
Organism=Drosophila melanogaster, GI281363737, Length=351, Percent_Identity=30.7692307692308, Blast_Score=201, Evalue=5e-52,
Organism=Drosophila melanogaster, GI19920834, Length=359, Percent_Identity=29.2479108635098, Blast_Score=142, Evalue=5e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006089
- InterPro:   IPR006092
- InterPro:   IPR006090
- InterPro:   IPR006091
- InterPro:   IPR009075
- InterPro:   IPR013786
- InterPro:   IPR009100 [H]

Pfam domain/function: PF00441 Acyl-CoA_dh_1; PF02770 Acyl-CoA_dh_M; PF02771 Acyl-CoA_dh_N [H]

EC number: NA

Molecular weight: Translated: 40617; Mature: 40486

Theoretical pI: Translated: 5.46; Mature: 5.46

Prosite motif: PS00072 ACYL_COA_DH_1 ; PS00073 ACYL_COA_DH_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAERQLPSSEARELIELTATMCDRELAPRVTEYEAASRFPREEFAVLGKAGLLSLPYPE
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHCCCCEEECCCCC
SFGGGEQPYEVYLQVLEEISYRWAAVAVGVSVHALSCYPLATFGTPEQQEEHLPRLLSGD
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCCHHHHHHHHHHCCH
LLGAYCLSEAHAGSDPAAMRVTATATDDGYLLNGTKAWVTHGGAADFYTVFARTSSDTRG
HHHHHHHHHHCCCCCCCEEEEEEEECCCCEEECCCEEEEECCCCCCEEEEEEECCCCCCC
GISCFLVDAGTPNIRFHPPEKKMGLTASPTTQISFDDVAVPASRLIGKVGQGLSIALSAL
CEEEEEEECCCCCCEECCCHHHCCCCCCCCCEEECCHHHCCHHHHHHHHCCCHHHHHHHH
DSGRLGIAATAVGLGQRALDDAVAYAKEREAFGKAIIDHQGLGFLLADMAAAVESARATT
CCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
LAAARRRDAGLQYGRAASVAKLVATDAAMKVTEDAVQVLGGAGYTKDFPVERYMREAKVM
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
QIFEGTNQIQRLVISRHLARG
HHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
PAERQLPSSEARELIELTATMCDRELAPRVTEYEAASRFPREEFAVLGKAGLLSLPYPE
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHCCCCEEECCCCC
SFGGGEQPYEVYLQVLEEISYRWAAVAVGVSVHALSCYPLATFGTPEQQEEHLPRLLSGD
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCCHHHHHHHHHHCCH
LLGAYCLSEAHAGSDPAAMRVTATATDDGYLLNGTKAWVTHGGAADFYTVFARTSSDTRG
HHHHHHHHHHCCCCCCCEEEEEEEECCCCEEECCCEEEEECCCCCCEEEEEEECCCCCCC
GISCFLVDAGTPNIRFHPPEKKMGLTASPTTQISFDDVAVPASRLIGKVGQGLSIALSAL
CEEEEEEECCCCCCEECCCHHHCCCCCCCCCEEECCHHHCCHHHHHHHHCCCHHHHHHHH
DSGRLGIAATAVGLGQRALDDAVAYAKEREAFGKAIIDHQGLGFLLADMAAAVESARATT
CCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
LAAARRRDAGLQYGRAASVAKLVATDAAMKVTEDAVQVLGGAGYTKDFPVERYMREAKVM
HHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHH
QIFEGTNQIQRLVISRHLARG
HHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]