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The map label for this gene is idnD [H]

Identifier: 158318102

GI number: 158318102

Start: 7727496

End: 7728119

Strand: Reverse

Name: idnD [H]

Synonym: Franean1_6366

Alternate gene names: 158318102

Gene position: 7728119-7727496 (Counterclockwise)

Preceding gene: 158318103

Following gene: 158318100

Centisome position: 86.04

GC content: 73.4

Gene sequence:

>624_bases
GTGCCGACCCACAAGGTCCTCGAGATACCGGCCGGGCTTGACGTCTCGAACGCCTCGCTGGCCGAGCCCGCCGCGGTCGC
CTGGCACGGCGCCCGCGTCGGCGGGACCGCGCCGGGCCGGACCGTTGCCGTCGTCGGCGGCGGTTCGATCGGCCAGCTGG
CGGCCGTCGCGGCCCAGACCCAGGGCGCTGCCGAGGTCGTCATGGAAGCCCGCTACCCCCACCAGCACGCGATCCGCGAG
CGGATGGGCGTCGGGGAGCCCAGGGCGGGCGAGCGCTACGACGTGGTGATCGAGGCCGCGGGGTCACCCAGCTCCCTGCG
GCGCAGCGTCGAGCTGGTGAAGCCAGGCGGCACCGTCTCGCTCCTGGGCGTCCATCAGGGCGGTATCGACGTGCCGTACT
CGTCGTTGTTGACCAAGGAGGTCACGCTGGTCGCGTCGATGGGGTACTGCGGGCACGCCGGCCGGCGGGAGATGCTTCAG
GCCGCCGAGATGCTCGCGGCGCGCCCTGAGATCCCGGACTCGCTCATCACCCATCGCTTCCCGCTCGAGGACGCGGCCGA
GGCCTTCCGGGTGGCGGGCGACCGCGAGTCGGGCGCGGTCAAGGTCGTCGTCGAGGTTGGCTGA

Upstream 100 bases:

>100_bases
GTGCGACTTCTGCCGGGAGGGCCGGAACAACCTCTGCGACCAGTCCACGAGGAAGGCTCTCGGCATCATGTAGAACGGCG
GCATGGTGGAGCAGTTCCGG

Downstream 100 bases:

>100_bases
GCTGGTCCCGGCCGTCCGTGGTGATGGCCGGGTCTCCGTCTGTCGCCGCGGCACGCGCAGGAAAGGCCCCGGGGGAGAGT
CCCTTCAGGAGGAACACCTT

Product: alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 207; Mature: 206

Protein sequence:

>207_residues
MPTHKVLEIPAGLDVSNASLAEPAAVAWHGARVGGTAPGRTVAVVGGGSIGQLAAVAAQTQGAAEVVMEARYPHQHAIRE
RMGVGEPRAGERYDVVIEAAGSPSSLRRSVELVKPGGTVSLLGVHQGGIDVPYSSLLTKEVTLVASMGYCGHAGRREMLQ
AAEMLAARPEIPDSLITHRFPLEDAAEAFRVAGDRESGAVKVVVEVG

Sequences:

>Translated_207_residues
MPTHKVLEIPAGLDVSNASLAEPAAVAWHGARVGGTAPGRTVAVVGGGSIGQLAAVAAQTQGAAEVVMEARYPHQHAIRE
RMGVGEPRAGERYDVVIEAAGSPSSLRRSVELVKPGGTVSLLGVHQGGIDVPYSSLLTKEVTLVASMGYCGHAGRREMLQ
AAEMLAARPEIPDSLITHRFPLEDAAEAFRVAGDRESGAVKVVVEVG
>Mature_206_residues
PTHKVLEIPAGLDVSNASLAEPAAVAWHGARVGGTAPGRTVAVVGGGSIGQLAAVAAQTQGAAEVVMEARYPHQHAIRER
MGVGEPRAGERYDVVIEAAGSPSSLRRSVELVKPGGTVSLLGVHQGGIDVPYSSLLTKEVTLVASMGYCGHAGRREMLQA
AEMLAARPEIPDSLITHRFPLEDAAEAFRVAGDRESGAVKVVVEVG

Specific function: Catalyzes the NADH/NADPH-dependent oxidation of L- idonate to 5-ketogluconate (5KG) [H]

COG id: COG1063

COG function: function code ER; Threonine dehydrogenase and related Zn-dependent dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI156627571, Length=199, Percent_Identity=28.1407035175879, Blast_Score=73, Evalue=2e-13,
Organism=Escherichia coli, GI1790718, Length=209, Percent_Identity=29.6650717703349, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI226510992, Length=207, Percent_Identity=30.4347826086957, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1788073, Length=220, Percent_Identity=23.1818181818182, Blast_Score=69, Evalue=2e-13,
Organism=Escherichia coli, GI1788075, Length=225, Percent_Identity=24.4444444444444, Blast_Score=65, Evalue=2e-12,
Organism=Escherichia coli, GI1790045, Length=218, Percent_Identity=24.7706422018349, Blast_Score=65, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6323099, Length=219, Percent_Identity=27.3972602739726, Blast_Score=83, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6322619, Length=210, Percent_Identity=25.2380952380952, Blast_Score=69, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6319955, Length=210, Percent_Identity=25.2380952380952, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.1.1.264 [H]

Molecular weight: Translated: 21429; Mature: 21297

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTHKVLEIPAGLDVSNASLAEPAAVAWHGARVGGTAPGRTVAVVGGGSIGQLAAVAAQT
CCCCCEEECCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCEEEEEECCCHHHHHHHHHHC
QGAAEVVMEARYPHQHAIRERMGVGEPRAGERYDVVIEAAGSPSSLRRSVELVKPGGTVS
CCHHHHHHHCCCCHHHHHHHHHCCCCCCCCCEEEEEEEECCCHHHHHHHHEEECCCCCEE
LLGVHQGGIDVPYSSLLTKEVTLVASMGYCGHAGRREMLQAAEMLAARPEIPDSLITHRF
EEEEECCCCCCCHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHCCC
PLEDAAEAFRVAGDRESGAVKVVVEVG
CHHHHHHHHHHCCCCCCCEEEEEEEEC
>Mature Secondary Structure 
PTHKVLEIPAGLDVSNASLAEPAAVAWHGARVGGTAPGRTVAVVGGGSIGQLAAVAAQT
CCCCEEECCCCCCCCCCCCCCCCCEEECCCCCCCCCCCCEEEEEECCCHHHHHHHHHHC
QGAAEVVMEARYPHQHAIRERMGVGEPRAGERYDVVIEAAGSPSSLRRSVELVKPGGTVS
CCHHHHHHHCCCCHHHHHHHHHCCCCCCCCCEEEEEEEECCCHHHHHHHHEEECCCCCEE
LLGVHQGGIDVPYSSLLTKEVTLVASMGYCGHAGRREMLQAAEMLAARPEIPDSLITHRF
EEEEECCCCCCCHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHCCC
PLEDAAEAFRVAGDRESGAVKVVVEVG
CHHHHHHHHHHCCCCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 9658018 [H]