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The map label for this gene is htrA [H]

Identifier: 158318071

GI number: 158318071

Start: 7690396

End: 7691514

Strand: Reverse

Name: htrA [H]

Synonym: Franean1_6331

Alternate gene names: 158318071

Gene position: 7691514-7690396 (Counterclockwise)

Preceding gene: 158318075

Following gene: 158318062

Centisome position: 85.63

GC content: 70.51

Gene sequence:

>1119_bases
ATGGACATGGGTCATCTCTCAAGGAGCAGGAGATTGCGGCGGTGGCTCGCCCTGCCGGAGACTCCCAGACCGTCGATCCG
GCACAGGTCGGAGTTTTCGGCCTGGATCGTGGCCGCTGGCCTGGCGGCTGGCGTCCTGTTCGGGACGGCGGCGTGCGGTA
CCGCGACCGACGACGCATCCATGTCCCGGGCCGAGACCACGAACTCGCAGCCCGCCGGACTCCCCGCCGTGGTACGCGAC
GCCGAGTCGTCCGTGGTCACGATCTTCGTCGGAAACGGGCTGGGCAGTGGCGTCGTCTACCGAGCCGACGGCGTCATCGT
CACCAACGAGCATGTCGTACGGTCCGCGGCCGACCGCAGGGTCGAGGTGGCCTTCGCCGACGGCCGCCGAGCCCCGGGCC
GAGTGCAGGCCGCCGACCGGATCAGCGACATCGCGGTCGTCAAGGTCGATCGGAGCGGCCTGCCCACCCTGACGTTCCGT
AGCGAGCTTCCCCAGGTGGGCGAGCTGGCCGTGGCGATCGGTAGCCCGCTTGGGTTCGAGAACAGCGCCACCGCCGGCAT
CGTCTCCGGGCTGAATCGCACCCTGCCGGCATCCGGCCAGCCCGGCCGCCTAGGCCAGCCGCTGGTCGACCTGATCCAGA
CCGACGCGGCGATCTCCCCCGGCAACTCCGGTGGGGCGCTCCTGGACGGGCAGGGCCGCGTCCTGGGCATCAACGAGGCC
TACGTGCCCCCGTCGGAGGGGGCTGTCTCCCTGGGCTTCGCGATCCCGTCAGCCACCGTTGTCGACGCTGCCGATCAACT
GCTGCGCACTGGCGAGGTGCAGCACGCCTTCCTCGGCGTCCAGGTCACCAGCCTCACGCCCGAAGTCGCCCGGCAGCTCG
ACATCCAGGTCGACAGCGGCGTCCTGGTGCTCTTTGTCGCCGACCAAGGTCCGGCCGACCGTGCCGGTGTCCGGCTCGGC
GATGTGATCCGCACCTTCAACGGCGAGCCGGTGAGATCCCCCACCGACTTCCTGGCCCAACTCCGCAGTGTCGACCCCGG
CCGGCAGGTGACGCTCGGTATCCGCCGCAACGGCGACGACCTCGAGGTGAAGGCCACCGTCGCAGACCGGCCCGCCTGA

Upstream 100 bases:

>100_bases
ACCTTCTACGCAACTCCAGCCGCCGTCACCCCGTTACCGTTACCGCATCCCCGCAAACGTCTCGCAGCGGCGCGTTTACG
CAAGGAAGCGCGGGTATGGC

Downstream 100 bases:

>100_bases
CCAGGGCCGGAGGAGGGCGGTGTTGCATTGCGAGGATGCGGCGCATGCCAGGACCTCGGGCAGTCTCGGCCAGACGGCCT
GGGTGAGCTCGGTGAACGCC

Product: 2-alkenal reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MDMGHLSRSRRLRRWLALPETPRPSIRHRSEFSAWIVAAGLAAGVLFGTAACGTATDDASMSRAETTNSQPAGLPAVVRD
AESSVVTIFVGNGLGSGVVYRADGVIVTNEHVVRSAADRRVEVAFADGRRAPGRVQAADRISDIAVVKVDRSGLPTLTFR
SELPQVGELAVAIGSPLGFENSATAGIVSGLNRTLPASGQPGRLGQPLVDLIQTDAAISPGNSGGALLDGQGRVLGINEA
YVPPSEGAVSLGFAIPSATVVDAADQLLRTGEVQHAFLGVQVTSLTPEVARQLDIQVDSGVLVLFVADQGPADRAGVRLG
DVIRTFNGEPVRSPTDFLAQLRSVDPGRQVTLGIRRNGDDLEVKATVADRPA

Sequences:

>Translated_372_residues
MDMGHLSRSRRLRRWLALPETPRPSIRHRSEFSAWIVAAGLAAGVLFGTAACGTATDDASMSRAETTNSQPAGLPAVVRD
AESSVVTIFVGNGLGSGVVYRADGVIVTNEHVVRSAADRRVEVAFADGRRAPGRVQAADRISDIAVVKVDRSGLPTLTFR
SELPQVGELAVAIGSPLGFENSATAGIVSGLNRTLPASGQPGRLGQPLVDLIQTDAAISPGNSGGALLDGQGRVLGINEA
YVPPSEGAVSLGFAIPSATVVDAADQLLRTGEVQHAFLGVQVTSLTPEVARQLDIQVDSGVLVLFVADQGPADRAGVRLG
DVIRTFNGEPVRSPTDFLAQLRSVDPGRQVTLGIRRNGDDLEVKATVADRPA
>Mature_372_residues
MDMGHLSRSRRLRRWLALPETPRPSIRHRSEFSAWIVAAGLAAGVLFGTAACGTATDDASMSRAETTNSQPAGLPAVVRD
AESSVVTIFVGNGLGSGVVYRADGVIVTNEHVVRSAADRRVEVAFADGRRAPGRVQAADRISDIAVVKVDRSGLPTLTFR
SELPQVGELAVAIGSPLGFENSATAGIVSGLNRTLPASGQPGRLGQPLVDLIQTDAAISPGNSGGALLDGQGRVLGINEA
YVPPSEGAVSLGFAIPSATVVDAADQLLRTGEVQHAFLGVQVTSLTPEVARQLDIQVDSGVLVLFVADQGPADRAGVRLG
DVIRTFNGEPVRSPTDFLAQLRSVDPGRQVTLGIRRNGDDLEVKATVADRPA

Specific function: A putative protease, its function overlaps that of the related putative proteases HhoA and HhoB [H]

COG id: COG0265

COG function: function code O; Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential). Cell outer membrane (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Homo sapiens, GI4506141, Length=284, Percent_Identity=34.1549295774648, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI24308541, Length=280, Percent_Identity=34.6428571428571, Blast_Score=127, Evalue=2e-29,
Organism=Homo sapiens, GI22129776, Length=283, Percent_Identity=32.5088339222615, Blast_Score=122, Evalue=4e-28,
Organism=Homo sapiens, GI7019477, Length=290, Percent_Identity=35.8620689655172, Blast_Score=120, Evalue=3e-27,
Organism=Escherichia coli, GI1789629, Length=278, Percent_Identity=37.7697841726619, Blast_Score=177, Evalue=9e-46,
Organism=Escherichia coli, GI1786356, Length=274, Percent_Identity=37.2262773722628, Blast_Score=165, Evalue=4e-42,
Organism=Escherichia coli, GI1789630, Length=355, Percent_Identity=30.1408450704225, Blast_Score=141, Evalue=8e-35,
Organism=Drosophila melanogaster, GI24646839, Length=292, Percent_Identity=30.1369863013699, Blast_Score=118, Evalue=6e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR009003
- InterPro:   IPR001254
- InterPro:   IPR001940 [H]

Pfam domain/function: PF00595 PDZ; PF00089 Trypsin [H]

EC number: 3.4.21.- [C]

Molecular weight: Translated: 38768; Mature: 38768

Theoretical pI: Translated: 5.78; Mature: 5.78

Prosite motif: PS50106 PDZ

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDMGHLSRSRRLRRWLALPETPRPSIRHRSEFSAWIVAAGLAAGVLFGTAACGTATDDAS
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
MSRAETTNSQPAGLPAVVRDAESSVVTIFVGNGLGSGVVYRADGVIVTNEHVVRSAADRR
CCHHHCCCCCCCCCCHHEECCCCCEEEEEEECCCCCCEEEECCCEEEECCHHHHHHCCCE
VEVAFADGRRAPGRVQAADRISDIAVVKVDRSGLPTLTFRSELPQVGELAVAIGSPLGFE
EEEEEECCCCCCCCCCHHHCCCCEEEEEECCCCCCEEEEHHCCCCHHHEEEEECCCCCCC
NSATAGIVSGLNRTLPASGQPGRLGQPLVDLIQTDAAISPGNSGGALLDGQGRVLGINEA
CCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCEEECCCCCEEECCCC
YVPPSEGAVSLGFAIPSATVVDAADQLLRTGEVQHAFLGVQVTSLTPEVARQLDIQVDSG
CCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCEEEEEEEEEECCCHHHHHHEEEEECCC
VLVLFVADQGPADRAGVRLGDVIRTFNGEPVRSPTDFLAQLRSVDPGRQVTLGIRRNGDD
EEEEEEECCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCC
LEVKATVADRPA
EEEEEEECCCCC
>Mature Secondary Structure
MDMGHLSRSRRLRRWLALPETPRPSIRHRSEFSAWIVAAGLAAGVLFGTAACGTATDDAS
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCC
MSRAETTNSQPAGLPAVVRDAESSVVTIFVGNGLGSGVVYRADGVIVTNEHVVRSAADRR
CCHHHCCCCCCCCCCHHEECCCCCEEEEEEECCCCCCEEEECCCEEEECCHHHHHHCCCE
VEVAFADGRRAPGRVQAADRISDIAVVKVDRSGLPTLTFRSELPQVGELAVAIGSPLGFE
EEEEEECCCCCCCCCCHHHCCCCEEEEEECCCCCCEEEEHHCCCCHHHEEEEECCCCCCC
NSATAGIVSGLNRTLPASGQPGRLGQPLVDLIQTDAAISPGNSGGALLDGQGRVLGINEA
CCCHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCEEECCCCCEEECCCC
YVPPSEGAVSLGFAIPSATVVDAADQLLRTGEVQHAFLGVQVTSLTPEVARQLDIQVDSG
CCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCEEEEEEEEEECCCHHHHHHEEEEECCC
VLVLFVADQGPADRAGVRLGDVIRTFNGEPVRSPTDFLAQLRSVDPGRQVTLGIRRNGDD
EEEEEEECCCCCCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCCEEEEEEECCCCC
LEVKATVADRPA
EEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]