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The map label for this gene is ubiE [C]

Identifier: 158317951

GI number: 158317951

Start: 7546745

End: 7547353

Strand: Reverse

Name: ubiE [C]

Synonym: Franean1_6211

Alternate gene names: 158317951

Gene position: 7547353-7546745 (Counterclockwise)

Preceding gene: 158317952

Following gene: 158317950

Centisome position: 84.03

GC content: 69.46

Gene sequence:

>609_bases
ATGGGCTTCTACGACGACCAGATGCTGCCCCGGTTCATCGACCTTGCCCTCGGGAGGCCGATGGAGCCCACCCGGGCCCG
CGTCACCACCGGCCTGTCCGGCGAGGTCCTGGAGATCGGGTTCGGTTCCGGGCGTAACCTGCCCCACCTTCCACCTGAAG
TCACCCGGCTCCTGGCTGTGGAACCCGCGGCCGTCGGCCGCAGGCTGGCGGCCCGCCGCATCGCCGCCGCCCCCATCCCG
GTCGAGTTCGTCGGCGACGACAGCCAGCGGCTACCCGTCCCGGACGGATCGGTGGACCACGTGCTGGTCACGTGGACCCT
GTGCACCATCCCGGACGTCGACCGGGCGCTGCGTGAGGCGCGCCGGGTGTTGCGACCCGGCGGCACGGTGCACTTCGTCG
AGCATGGCCGTTCACCCAACCACCGTGTCGCCCGGCGGCAAGAGCGCCTCACGCCCCTGTGGGGAAAGGTGTTCGGTGGC
TGCCACCTCAACCGGCCTGTCGATAAGTTGATCGAAAACGCCGGGTTCACGCTCGACACCGTCCAGACGTACCGGATGGG
CGGGCCGGAGCTCTTCAGCTTCGCCTACGAGGGCATCGCGTCGAAGTAA

Upstream 100 bases:

>100_bases
CATGGAATGCGACCCGGCCTGACACAACAGAGCCGGACAGGTTATTCCGACCGCCGTGGAGCTGACCTGCGTCGATATCA
AAGAGAACCAGGGAGAAGTG

Downstream 100 bases:

>100_bases
GACTGACCTATAGGGCGACGGAAATTAGTCTGGGTCTGTGCCTGGAATGAATGTGACGGCGCGGCCCCTGCCGCGCTGGT
CGCTAACCGTGCGAAGCTGC

Product: type 11 methyltransferase

Products: S-Adenosyl-L-Homocysteine; @OCTA02.txt*2- Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol!; Menaquinol. [C]

Alternate protein names: Methyltransferase; Ubiquinone/Menaquinone Biosynthesis Methyltransferase; SAM-Dependent Methyltransferase; UbiE/COQ5 Family Methlytransferase; Methyltransferase UbiE/COQ5 Family; Phosphatidylethanolamine N-Methyltransferase; Methylase Involved In Ubiquinone/Menaquinone Biosynthesis; Methyltransferase Domain Family; Phospholipid Methyltransferase; Sam Dependent Methyltransferase; Ubiquinone/Menaquinone Biosynthesis Methyltransferase UbiE; UbiE Ubiquinone/Menaquinone Biosynthesis Methyltransferase; Generic Methyltransferase; SAM-Dependent Methyltransferase UbiE/COQ5 Family; Ubiquinone/Menaquinone Biosynthesis Methyl Transferase; Methyltransferase Domain Family Protein; UbiE/COQ5 Methyltransferase; Response Regulator Receiver Protein

Number of amino acids: Translated: 202; Mature: 201

Protein sequence:

>202_residues
MGFYDDQMLPRFIDLALGRPMEPTRARVTTGLSGEVLEIGFGSGRNLPHLPPEVTRLLAVEPAAVGRRLAARRIAAAPIP
VEFVGDDSQRLPVPDGSVDHVLVTWTLCTIPDVDRALREARRVLRPGGTVHFVEHGRSPNHRVARRQERLTPLWGKVFGG
CHLNRPVDKLIENAGFTLDTVQTYRMGGPELFSFAYEGIASK

Sequences:

>Translated_202_residues
MGFYDDQMLPRFIDLALGRPMEPTRARVTTGLSGEVLEIGFGSGRNLPHLPPEVTRLLAVEPAAVGRRLAARRIAAAPIP
VEFVGDDSQRLPVPDGSVDHVLVTWTLCTIPDVDRALREARRVLRPGGTVHFVEHGRSPNHRVARRQERLTPLWGKVFGG
CHLNRPVDKLIENAGFTLDTVQTYRMGGPELFSFAYEGIASK
>Mature_201_residues
GFYDDQMLPRFIDLALGRPMEPTRARVTTGLSGEVLEIGFGSGRNLPHLPPEVTRLLAVEPAAVGRRLAARRIAAAPIPV
EFVGDDSQRLPVPDGSVDHVLVTWTLCTIPDVDRALREARRVLRPGGTVHFVEHGRSPNHRVARRQERLTPLWGKVFGGC
HLNRPVDKLIENAGFTLDTVQTYRMGGPELFSFAYEGIASK

Specific function: Methyltransferase Required For The Conversion Of Dimethylmenaquinone (Dmkh2) To Menaquinone (Mkh2) And The Conversion Of 2-Polyprenyl-6-Methoxy-1,4-Benzoquinol (Ddmqh2) To 2-Polyprenyl-3-Methyl-6-Methoxy-1,4-Benzoquinol (Dmqh2). [C]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI164663805, Length=168, Percent_Identity=35.1190476190476, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI89145417, Length=170, Percent_Identity=32.3529411764706, Blast_Score=82, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.1.1.- [C]

Molecular weight: Translated: 22324; Mature: 22193

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: PS01184 UBIE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGFYDDQMLPRFIDLALGRPMEPTRARVTTGLSGEVLEIGFGSGRNLPHLPPEVTRLLAV
CCCCCHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHC
EPAAVGRRLAARRIAAAPIPVEFVGDDSQRLPVPDGSVDHVLVTWTLCTIPDVDRALREA
CHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCEEEEEEEEECCCCHHHHHHHH
RRVLRPGGTVHFVEHGRSPNHRVARRQERLTPLWGKVFGGCHLNRPVDKLIENAGFTLDT
HHHHCCCCEEEEEECCCCCCHHHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHHCCCEEEH
VQTYRMGGPELFSFAYEGIASK
HHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure 
GFYDDQMLPRFIDLALGRPMEPTRARVTTGLSGEVLEIGFGSGRNLPHLPPEVTRLLAV
CCCCHHHHHHHHHHHCCCCCCCCHHHHCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHC
EPAAVGRRLAARRIAAAPIPVEFVGDDSQRLPVPDGSVDHVLVTWTLCTIPDVDRALREA
CHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCCEEEEEEEEECCCCHHHHHHHH
RRVLRPGGTVHFVEHGRSPNHRVARRQERLTPLWGKVFGGCHLNRPVDKLIENAGFTLDT
HHHHCCCCEEEEEECCCCCCHHHHHHHHHCCHHHHHHHCCCCCCCCHHHHHHHCCCEEEH
VQTYRMGGPELFSFAYEGIASK
HHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: S-Adenosyl-L-Methionine; 2-Polyprenyl-6- Methoxy-1,4-Benzoquinol; Demethylmenaquinol [C]

Specific reaction: S-Adenosyl-L-Methionine + @OCTA02.txt*2-Polyprenyl-6- Methoxy-1,4-Benzoquinol! = S-Adenosyl-L-Homocysteine + 2- Polyprenyl-3-Methyl-6-Methoxy -1,4-Benzoquinol S-Adenosyl-L-Methionine + Demethylmenaquinol = S-Adenosyl-L-Homocysteine + Menaquinol. [C]

General reaction: Transferring one-carbon groups; Methyltransferases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA