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The map label for this gene is selA [H]

Identifier: 158317925

GI number: 158317925

Start: 7512527

End: 7513894

Strand: Direct

Name: selA [H]

Synonym: Franean1_6183

Alternate gene names: 158317925

Gene position: 7512527-7513894 (Clockwise)

Preceding gene: 158317921

Following gene: 158317926

Centisome position: 83.64

GC content: 76.32

Gene sequence:

>1368_bases
GTGATCAACGCCACCGGCATTCTCCTGCACGACGGCCTCGGCCGCGCGCCGCTGTCCCCGGCGGCCCGCACCGCGCTCGA
CGCCGCGGCCGGGACCTGCGACGTCGAGGTCGACCTGGCCACGGGTCGCCGCGGCCGGCGCGGCCGCACGACGATGACCG
CGCTGGCCGCGGCCGTGCCAATGGCCCGTTCCGTGCACGTGGTCAACAACAACGCGGCCGCGCTCATCCTGTCGGCCGCG
GCGCTCGCGGGCCGCCGGGAGATAGTCGTCAGCCGCGGCGAGCTCATCGAGACAGCCGACGGGCTCCGCCTGCCCGAGCT
GCTGACGTCGACCGGAGCCCGGCTGCGCGAGGTTGGGACCACAAATCGGACCACACTCGGCGACTACGCCGACGCCATCG
GGCCAGGCACCGGTTTCGTACTTCGTATACATCCGCCCAGCTACCGGGTCGTCGGGCTGACGGCGGCCCCGGCGCTCGCC
GATCTCGCCGAGCTGTGCGCCGGCCGCGGTGTGCCACTCGTCGGCGATCCCGGATCCGGACTGCTGCACCCCGAGCCCGC
CCTGCCCGACGAACCGGACGCCTCGACCTGGCTGAGCTGCGGGGTCAGCCTGGTCATCACCTGCGGCGACAAGCTTCTCG
GCGGGCCGCAGTGCGGCCTCGTCCTGGGCCGCGCGGACCTGGTCGACCGGCTGCGCCGGCATCCGCTCGCCCGCGCCCTG
CGAGTGGGCAAACTGACGTTGGCCGCGCTGGAGGCCACGCTGGGCACCGGGGACAACCCCGTCCGCAGGTCGCTGCGCGC
CGAGCCCGCCGAGCTGCGGCACCGGGCCGAGCGGCTGGCGTCCTGGCTGCGGCAGTCCGGGGTCCCTGCCTCCGCCGTGA
CCAGCCGGGCGGTCGTCGGCTCGGACGGCATCGACGACACCGCCCGGGCCGGGGCCGCCGTGCGCCGCGGCGCCGTCGGA
GTCGGAGCGGGCCACGGCGGCCACACAGTCTACGGGTCGGGGCCGGACGTGTGGGAGAGCGGCCTGCCGAGTGCGGCCGT
CGCGCTGGACGCGGCCCTGGCCGCCTTCCTGCGCCGCGGCCGCCCGTCCGTCCTCGGACGGGTCGAGCAGGGCTGCTGCC
TGCTGGATCTGCGGTCGGTTCCACCGGACCTGGACCCCGTCCTCGCCGCGACGGTGCTCGCCGCCGCGGCCGAGTCGGGT
ACCGCCACCGCCGGCGACATCCACGCGCTCTCCGCGGACGCGCCCGCCTCCGCCGTCCCTTCGGCGGCCACCGGCTGGAC
GGATCCGGCACGCCGGGAGGATCCGGCGGGCTGGGAAGGGCCGGGCGCCGACGCCGGGTCCGACGTCGACGCGGTCACCT
TGCAGTGA

Upstream 100 bases:

>100_bases
TCCAGGTCGACCTCTTACCGAGCCGACGCGGTTCCTCACCACGCCCGCGCCGACCGCCGTGCTGGTGGCGCCCGCCCGGC
AGGCCGGAGGCCCACGCCCG

Downstream 100 bases:

>100_bases
GCGAACCGGCGTGAGCGTGGCCCGGTGACCCTCGGCCCGGTCAGCGAGGGCTCGGTAAGCCGTGGCCCCGTCAGCCGAGA
CTCGGTCGGCCGCGGCGCGG

Product: selenocysteine synthase

Products: NA

Alternate protein names: Selenocysteine synthase; Sec synthase; Selenocysteinyl-tRNA(Sec) synthase [H]

Number of amino acids: Translated: 455; Mature: 455

Protein sequence:

>455_residues
MINATGILLHDGLGRAPLSPAARTALDAAAGTCDVEVDLATGRRGRRGRTTMTALAAAVPMARSVHVVNNNAAALILSAA
ALAGRREIVVSRGELIETADGLRLPELLTSTGARLREVGTTNRTTLGDYADAIGPGTGFVLRIHPPSYRVVGLTAAPALA
DLAELCAGRGVPLVGDPGSGLLHPEPALPDEPDASTWLSCGVSLVITCGDKLLGGPQCGLVLGRADLVDRLRRHPLARAL
RVGKLTLAALEATLGTGDNPVRRSLRAEPAELRHRAERLASWLRQSGVPASAVTSRAVVGSDGIDDTARAGAAVRRGAVG
VGAGHGGHTVYGSGPDVWESGLPSAAVALDAALAAFLRRGRPSVLGRVEQGCCLLDLRSVPPDLDPVLAATVLAAAAESG
TATAGDIHALSADAPASAVPSAATGWTDPARREDPAGWEGPGADAGSDVDAVTLQ

Sequences:

>Translated_455_residues
MINATGILLHDGLGRAPLSPAARTALDAAAGTCDVEVDLATGRRGRRGRTTMTALAAAVPMARSVHVVNNNAAALILSAA
ALAGRREIVVSRGELIETADGLRLPELLTSTGARLREVGTTNRTTLGDYADAIGPGTGFVLRIHPPSYRVVGLTAAPALA
DLAELCAGRGVPLVGDPGSGLLHPEPALPDEPDASTWLSCGVSLVITCGDKLLGGPQCGLVLGRADLVDRLRRHPLARAL
RVGKLTLAALEATLGTGDNPVRRSLRAEPAELRHRAERLASWLRQSGVPASAVTSRAVVGSDGIDDTARAGAAVRRGAVG
VGAGHGGHTVYGSGPDVWESGLPSAAVALDAALAAFLRRGRPSVLGRVEQGCCLLDLRSVPPDLDPVLAATVLAAAAESG
TATAGDIHALSADAPASAVPSAATGWTDPARREDPAGWEGPGADAGSDVDAVTLQ
>Mature_455_residues
MINATGILLHDGLGRAPLSPAARTALDAAAGTCDVEVDLATGRRGRRGRTTMTALAAAVPMARSVHVVNNNAAALILSAA
ALAGRREIVVSRGELIETADGLRLPELLTSTGARLREVGTTNRTTLGDYADAIGPGTGFVLRIHPPSYRVVGLTAAPALA
DLAELCAGRGVPLVGDPGSGLLHPEPALPDEPDASTWLSCGVSLVITCGDKLLGGPQCGLVLGRADLVDRLRRHPLARAL
RVGKLTLAALEATLGTGDNPVRRSLRAEPAELRHRAERLASWLRQSGVPASAVTSRAVVGSDGIDDTARAGAAVRRGAVG
VGAGHGGHTVYGSGPDVWESGLPSAAVALDAALAAFLRRGRPSVLGRVEQGCCLLDLRSVPPDLDPVLAATVLAAAAESG
TATAGDIHALSADAPASAVPSAATGWTDPARREDPAGWEGPGADAGSDVDAVTLQ

Specific function: Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis [H]

COG id: COG1921

COG function: function code E; Selenocysteine synthase [seryl-tRNASer selenium transferase]

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the selA family [H]

Homologues:

Organism=Escherichia coli, GI2367248, Length=263, Percent_Identity=43.7262357414449, Blast_Score=172, Evalue=4e-44,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR018319
- InterPro:   IPR004534 [H]

Pfam domain/function: PF03841 SelA [H]

EC number: =2.9.1.1 [H]

Molecular weight: Translated: 46129; Mature: 46129

Theoretical pI: Translated: 6.60; Mature: 6.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MINATGILLHDGLGRAPLSPAARTALDAAAGTCDVEVDLATGRRGRRGRTTMTALAAAVP
CCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHH
MARSVHVVNNNAAALILSAAALAGRREIVVSRGELIETADGLRLPELLTSTGARLREVGT
HHCEEEEECCCCHHHHHHHHHHCCCCEEEEECCCHHHCCCCCCHHHHHHHCCHHHHHCCC
TNRTTLGDYADAIGPGTGFVLRIHPPSYRVVGLTAAPALADLAELCAGRGVPLVGDPGSG
CCCCCCHHHHHHCCCCCCEEEEECCCCEEEEEEECCHHHHHHHHHHCCCCCCEECCCCCC
LLHPEPALPDEPDASTWLSCGVSLVITCGDKLLGGPQCGLVLGRADLVDRLRRHPLARAL
CCCCCCCCCCCCCHHHHHHCCEEEEEEECHHHCCCCCCCEEECHHHHHHHHHHCHHHHHH
RVGKLTLAALEATLGTGDNPVRRSLRAEPAELRHRAERLASWLRQSGVPASAVTSRAVVG
HHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEEC
SDGIDDTARAGAAVRRGAVGVGAGHGGHTVYGSGPDVWESGLPSAAVALDAALAAFLRRG
CCCCCHHHHHHHHHHCCCCEECCCCCCCEEECCCCHHHHCCCCHHHHHHHHHHHHHHHCC
RPSVLGRVEQGCCLLDLRSVPPDLDPVLAATVLAAAAESGTATAGDIHALSADAPASAVP
CHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHCC
SAATGWTDPARREDPAGWEGPGADAGSDVDAVTLQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEC
>Mature Secondary Structure
MINATGILLHDGLGRAPLSPAARTALDAAAGTCDVEVDLATGRRGRRGRTTMTALAAAVP
CCCCCEEEEECCCCCCCCCHHHHHHHHHHCCCCEEEEEECCCCCCCCCCHHHHHHHHHHH
MARSVHVVNNNAAALILSAAALAGRREIVVSRGELIETADGLRLPELLTSTGARLREVGT
HHCEEEEECCCCHHHHHHHHHHCCCCEEEEECCCHHHCCCCCCHHHHHHHCCHHHHHCCC
TNRTTLGDYADAIGPGTGFVLRIHPPSYRVVGLTAAPALADLAELCAGRGVPLVGDPGSG
CCCCCCHHHHHHCCCCCCEEEEECCCCEEEEEEECCHHHHHHHHHHCCCCCCEECCCCCC
LLHPEPALPDEPDASTWLSCGVSLVITCGDKLLGGPQCGLVLGRADLVDRLRRHPLARAL
CCCCCCCCCCCCCHHHHHHCCEEEEEEECHHHCCCCCCCEEECHHHHHHHHHHCHHHHHH
RVGKLTLAALEATLGTGDNPVRRSLRAEPAELRHRAERLASWLRQSGVPASAVTSRAVVG
HHHHHHHHHHHHHHCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHEEC
SDGIDDTARAGAAVRRGAVGVGAGHGGHTVYGSGPDVWESGLPSAAVALDAALAAFLRRG
CCCCCHHHHHHHHHHCCCCEECCCCCCCEEECCCCHHHHCCCCHHHHHHHHHHHHHHHCC
RPSVLGRVEQGCCLLDLRSVPPDLDPVLAATVLAAAAESGTATAGDIHALSADAPASAVP
CHHHHHHHHCCEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCHHCC
SAATGWTDPARREDPAGWEGPGADAGSDVDAVTLQ
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA